RANI THERAPEUTICS HLDGS INC RANI
COM CL A · Common Stock · CUSIP 753018100
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Jose, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.50. Options: 2 managers hold calls ($8.3k notional), 0 hold puts (—).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 33 |
| Q4 2022 | 35 |
| Q1 2023 | 37 |
| Q2 2023 | 36 |
| Q3 2023 | 35 |
| Q4 2023 | 35 |
| Q1 2024 | 38 |
| Q2 2024 | 36 |
| Q3 2024 | 32 |
| Q4 2024 | 44 |
| Q1 2025 | 39 |
| Q2 2025 | 40 |
| Q3 2025 | 38 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 6 | 8 |
| Q1 2024 | 12 | 6 |
| Q2 2024 | 12 | 14 |
| Q3 2024 | 12 | 12 |
| Q4 2024 | 19 | 11 |
| Q1 2025 | 14 | 13 |
| Q2 2025 | 11 | 13 |
| Q3 2025 | 15 | 14 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $157.1k | $279.4k | 1.78 |
| Q1 2025 | $147.0k | $141.7k | 0.96 |
| Q2 2025 | $51.3k | $0 | 0.00 |
| Q3 2025 | $8.3k | $0 | 0.00 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +315.2k |
| HRT FINANCIAL LP | New | +113.2k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +106.4k |
| VANGUARD GROUP INC | Added | +84.9k |
| KESTRA PRIVATE WEALTH SERVICES, LLC | Added | +70.0k |
| CWA Asset Management Group, LLC | Added | +66.7k |
| XTX Topco Ltd | New | +44.1k |
| RENAISSANCE TECHNOLOGIES LLC | New | +24.9k |
| ACT Advisors, LLC. | New | +14.8k |
| UBS Group AG | Added | +7.1k |
Biggest sellers
| ARMISTICE CAPITAL, LLC | Sold out | -3.2m |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Sold out | -46.5k |
| GSA CAPITAL PARTNERS LLP | Sold out | -25.4k |
| Vanguard Personalized Indexing Management, LLC | Sold out | -15.4k |
| BANK OF AMERICA CORP /DE/ | Reduced | -13.4k |
| Janney Montgomery Scott LLC | Reduced | -6.0k |
| NORTHERN TRUST CORP | Reduced | -5.9k |
| OSAIC HOLDINGS, INC. | Reduced | -5.7k |
| Tower Research Capital LLC (TRC) | Reduced | -3.1k |
| RAYMOND JAMES FINANCIAL INC | Sold out | -3.0k |
Biggest calls
| SIMPLEX TRADING, LLC | Reduced | $5.0k11.4k shares |
| GROUP ONE TRADING LLC | Reduced | $3.3k6.7k shares |
Biggest puts
| None |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
InCube Labs, L.L.C.
13D · may seek influence
filed 2025-10-27
Stated purposeThe information set forth in Item 1 and Item 3 of this Amendment No. 1 is incorporate herein by reference. Item 4 of the Statement is hereby amended and supplemented as follows: In connection with a private placement, as promptly as possible following the closing, but in no event later than ninety (90) days following the closing date, the Issuer has agreed to use reasonable best efforts to: (a) amend the Issuer's Amended and Restated Certificate of Incorporation to, among other things, effect the following: (i) reduce the number of votes to which each share of Class B Common Stock is entitled from ten (10) votes to one (1) vote, (ii) eliminate the ability of the Issuer's stockholders to act by written consent, and (iii) include additional stockholder protective provisions (not including … Full filing |
22.1% |
| Invus Global Management, LLC 13G · passive investor new · filed 2025-10-23 | 10.0% |
| ARMISTICE CAPITAL, LLC 13G · institution filed 2025-08-15 | 9.9% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor no change · filed 2026-08-14 | 9.9% |
| Samsara BioCapital, L.P. 13D · may seek influence no change · filed 2026-05-28 | 9.9% |
| AWM Investment Company, Inc. 13G · institution new · filed 2026-02-13 | 9.9% |
Fell to 5% or below in the last year: VANGUARD CAPITAL MANAGEMENT LLC (4.5%, 2026-07-31), SymBiosis Capital Partners, LLC (4.4%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 3 | $190.0k | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 2 | $50.0k | 1 | $11.3k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
None reported in Q3 2025.
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.00% of their portfolio | 884.6k $442.3k | Added +84.9k |
| Nan Fung Group Holdings Ltd 0.41% of their portfolio | 493.6k $246.7k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 452.5k $226.2k | Added +315.2k |
| UNITED SERVICES AUTOMOBILE ASSOCIATION 0.01% of their portfolio | 302.7k $151.3k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 296.9k $148.4k | Added +106.4k |
| KESTRA PRIVATE WEALTH SERVICES, LLC 0.00% of their portfolio | 226.1k $113.0k | Added +70.0k |
| TAKEDA PHARMACEUTICAL CO LTD 0.62% of their portfolio | 203.2k $101.6k | Unchanged |
| CWA Asset Management Group, LLC 0.00% of their portfolio | 150.0k $75.0k | Added +66.7k |
| BlackRock, Inc. 0.00% of their portfolio | 120.2k $60.1k | Added +1.6k |
| HRT FINANCIAL LP 0.00% of their portfolio | 113.2k $56.0k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 97.0k $48.5k | Reduced -5.9k |
| UBS Group AG 0.00% of their portfolio | 69.1k $34.6k | Added +7.1k |
| LASRY MARC 0.21% of their portfolio | 62.9k $31.4k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 62.4k $31.2k | Unchanged |
| KING LUTHER CAPITAL MANAGEMENT CORP 0.00% of their portfolio | 58.0k $29.0k | Unchanged |
| Well Done, LLC 0.00% of their portfolio | 52.0k $26.0k | Unchanged |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 49.2k $25.0k | Reduced -6.0k |
| MOTCO 0.00% of their portfolio | 48.1k $24.1k | Unchanged |
| INSIGNEO ADVISORY SERVICES, LLC 0.00% of their portfolio | 47.5k $23.7k | Unchanged |
| XTX Topco Ltd 0.00% of their portfolio | 44.1k $22.0k | New |
| BROWN ADVISORY INC 0.00% of their portfolio | 32.9k $16.4k | Unchanged |
| Prime Capital Investment Advisors, LLC 0.00% of their portfolio | 27.2k $13.6k | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 24.9k $12.4k | New |
| Lafayette Investments, Inc. 0.00% of their portfolio | 19.9k $9.9k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 17.8k $8.9k | Reduced -13.4k |
| ACT Advisors, LLC. 0.00% of their portfolio | 14.8k $7.4k | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 12.6k $6.3k | Added +3.0k |
| CHOREO, LLC 0.00% of their portfolio | 11.8k $5.9k | Unchanged |
| Cerity Partners LLC 0.00% of their portfolio | 10.0k $5.0k | Unchanged |
| ISLAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 9.6k $4.8k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 6.8k $3.4k | Reduced -270 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.2k $3.1k | Reduced -3.1k |
| Allworth Financial LP 0.00% of their portfolio | 3.1k $1.6k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 1.0k $490 | Reduced -5.7k |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 980 $490 | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 819 $0 | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 142 $70 | Added +71 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 39 $0 | Reduced -23 |