Vault-13

PYXIS ONCOLOGY INC PYXS

COMMON STOCK · Common Stock · CUSIP 747324101

55 institutional holders +6 vs Q2 2023
7,812,2927.8m shares reported held*
17.6% of all shares outstanding*
$15.4mreported value*
14 new 15 added 13 reduced 7 sold out net sold ≈ $2.2m (-1.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 44.3m as of 2023-11-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.98. Options: 4 managers hold calls ($47.4k notional), 2 hold puts ($0).

Trends to Q3 2023

Institutional holders

Managers reporting a position, each quarter

0204060Q3 22: 38Q4 22: 32Q1 23: 48Q2 23: 49Q3 23: 5555Q3 22Q4 22Q1 23Q2 23Q3 23
Numbers
QuarterHolders
Q3 202238
Q4 202232
Q1 202348
Q2 202349
Q3 202355

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 13 bought or addedQ4 22: 15 cut or sold outQ4 22Q1 23: 32 bought or addedQ1 23: 15 cut or sold outQ1 23Q2 23: 35 bought or addedQ2 23: 23 cut or sold outQ2 23Q3 23: 29 bought or addedQ3 23: 20 cut or sold outQ3 23
Numbers
QuarterBought or addedCut or sold out
Q4 20221315
Q1 20233215
Q2 20233523
Q3 20232920

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25k$50k$75k$100kQ4 22 calls: $0Q4 22 puts: $0Q4 22P/C —Q1 23 calls: $0Q1 23 puts: $0Q1 23P/C —Q2 23 calls: $80.8kQ2 23 puts: $0Q2 23P/C 0.00Q3 23 calls: $47.4kQ3 23 puts: $0Q3 23P/C 0.00
Numbers
QuarterCallsPutsP/C
Q4 2022$0$0—
Q1 2023$0$0—
Q2 2023$80.8k$00.00
Q3 2023$47.4k$00.00

Biggest buyers

Decheng Capital Management III (Cayman), LLC New +326,810+326.8k
ExodusPoint Capital Management, LP Added +155,511+155.5k
DIMENSIONAL FUND ADVISORS LP Added +136,281+136.3k
Yu Fan New +69,303+69.3k
TWO SIGMA ADVISERS, LP Added +55,700+55.7k
Radcliffe Capital Management, L.P. New +53,288+53.3k
GEODE CAPITAL MANAGEMENT, LLC Added +45,512+45.5k
VANGUARD GROUP INC Added +43,794+43.8k
BlackRock Inc. Added +33,077+33.1k
Squarepoint Ops LLC New +22,556+22.6k

Biggest sellers

TANG CAPITAL MANAGEMENT LLC Sold out -1,787,775-1.8m
BRIDGEWAY CAPITAL MANAGEMENT, LLC Reduced -50,000-50.0k
GOLDMAN SACHS GROUP INC Sold out -45,974-46.0k
Cubist Systematic Strategies, LLC Reduced -38,205-38.2k
RENAISSANCE TECHNOLOGIES LLC Reduced -36,978-37.0k
ROYAL BANK OF CANADA Reduced -34,402-34.4k
Jump Financial, LLC Sold out -31,026-31.0k
MILLENNIUM MANAGEMENT LLC Sold out -30,878-30.9k
BANK OF AMERICA CORP /DE/ Reduced -29,829-29.8k
XTX Topco Ltd Sold out -15,236-15.2k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $47.0k23.6k shares
GROUP ONE TRADING LLC Reduced $398200 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
SIMPLEX TRADING, LLC Reduced $0100 shares

Biggest puts

CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
SIMPLEX TRADING, LLC Added $0200 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GordonMD Global Investments LP 13G · passive investor -1.1 pts · filed 2026-10-09 16.4% -1.1 pts 20.4m≈ $45.3m 2026-10-09
Sullivan Lara 13D · may seek influence +0.9 pts · filed 2025-04-02
Stated purposeItem 4 of the Schedule 13D is hereby amended and supplemented as follows: The response to Item 3 of this Amendment No. 5 is incorporated by reference herein. Full filing
11.2% +0.9 pts 7.5m≈ $22.7m 2025-04-02
BIOTECHNOLOGY VALUE FUND L P 13G · passive investor new · filed 2026-07-10 10.0% new 8.3m≈ $25.1m 2026-07-10
Laurion Capital Management LP 13G · institution filed 2026-02-09 7.7% 4.8m≈ $14.4m 2026-02-09
Coastlands Capital LP 13G · institution new · filed 2026-10-05 5.4% new 6.4m≈ $15.0m 2026-10-05

Insider purchases and sales in Q3 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q4 21: 4 buyingQ4 21: 0 sellingQ1 22: 0 buyingQ1 22: 0 sellingQ1 22Q2 22: 0 buyingQ2 22: 0 sellingQ3 22: 0 buyingQ3 22: 0 sellingQ3 22Q4 22: 0 buyingQ4 22: 0 sellingQ1 23: 0 buyingQ1 23: 0 sellingQ1 23Q2 23: 0 buyingQ2 23: 0 sellingQ3 23: 2 buyingQ3 23: 1 sellingQ3 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20214$12.5m0——
Q1 20220—0——
Q2 20220—0——
Q3 20220—0——
Q4 20220—0——
Q1 20230—0——
Q2 20230—0——
Q3 20232$73.5k1$81.4k—
DateInsiderTradeSharesPrice ValueTheir holding
2023-09-28 Connealy Pamela Ann CFO and COO Bought 8,000 $1.87 $15.0k8.0k shares +1%
2023-09-27 Connealy Pamela Ann CFO and COO Bought 6,426 $1.85 $11.9k6.4k shares +1%
2023-09-27 Wadhane Jitendra Chief Accounting Officer Bought 2,500 $1.87 $4.7k2.5k shares +1%
2023-09-25 Connealy Pamela Ann CFO and COO Bought 12,000 $1.67 $20.0k12.0k shares +2%
2023-09-25 Wadhane Jitendra Chief Accounting Officer Bought 5,000 $1.77 $8.8k5.0k shares +2%
2023-09-22 Connealy Pamela Ann CFO and COO Bought 5,000 $1.74 $8.7k5.0k shares +1%
2023-09-22 Wadhane Jitendra Chief Accounting Officer Bought 2,500 $1.74 $4.3k2.5k shares +1%
2023-09-18 Sullivan Lara President and CEO, director Sold 8,541 $2.10 $17.9k8.5k shares -<1%
2023-09-14 Sullivan Lara President and CEO, director Sold 100 $2.25 $225100 shares -<1%
2023-09-13 Sullivan Lara President and CEO, director Sold 3,000 $2.27 $6.8k3.0k shares -<1%
2023-09-12 Sullivan Lara President and CEO, director Sold 4,917 $2.25 $11.1k4.9k shares -<1%
2023-09-11 Sullivan Lara President and CEO, director Sold 20,000 $2.27 $45.4k20.0k shares -1%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q3 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Laurion Capital Management LP 0.16% of their portfolio NEW YORK, NY 3,170,8033.2m $6.3m $6.3m 0.16% Unchanged
2 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,140,2431.1m $2.3m $2.3m 0.00% Added +43.8k +43,794
3 ExodusPoint Capital Management, LP 0.01% of their portfolio NEW YORK, NY 415,072415.1k $826.0k $826.0k 0.01% Added +155.5k +155,511
4 HHLR ADVISORS, LTD. 0.02% of their portfolio GRAND CAYMAN, E9 382,606382.6k $761.4k $761.4k 0.02% Unchanged
5 Decheng Capital Management III (Cayman), LLC 0.22% of their portfolio Grand Cayman, E9 326,810326.8k $650.4k $650.4k 0.22% New
6 BlackRock Inc. 0.00% of their portfolio New York, NY 301,514301.5k $600.0k $600.0k 0.00% Added +33.1k +33,077
7 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 288,299288.3k $573.9k $573.9k 0.00% Added +45.5k +45,512
8 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 236,195236.2k $470.0k $470.0k 0.01% Reduced -50.0k -50,000
9 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 216,251216.3k $430.0k $430.0k 0.00% Reduced -37.0k -36,978
10 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 153,771153.8k $306.0k $306.0k 0.00% Added +136.3k +136,281
11 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 125,000125.0k $248.8k $248.8k 0.00% Unchanged
12 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 119,813119.8k $238.4k $238.4k 0.00% Added +11.4k +11,406
13 Harvest Investment Services, LLC 0.15% of their portfolio Oakbrook Terrace, IL 113,894113.9k $226.6k $226.6k 0.15% Reduced -2.5k -2,534
14 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 100,854100.9k $200.7k $200.7k 0.00% Reduced -29.8k -29,829
15 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 83,05583.1k $165.3k $165.3k 0.00% Added +9.4k +9,366
16 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 80,50080.5k $160.2k $160.2k 0.00% Added +55.7k +55,700
17 CORNERCAP INVESTMENT COUNSEL INC 0.03% of their portfolio Atlanta, GA 74,90374.9k $149.1k $149.1k 0.03% Reduced -1.0k -1,002
18 Yu Fan 9.78% of their portfolio CENTRAL, HONG KONG, K3 69,30369.3k $137.9k $137.9k 9.78% New
19 Radcliffe Capital Management, L.P. 0.00% of their portfolio BALA CYNWYD, PA 53,28853.3k $0 $0 0.00% New
20 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 52,74652.7k $105.0k $105.0k 0.00% Added +5.4k +5,353
21 UNIVERSITY OF CHICAGO 0.06% of their portfolio CHICAGO, IL 48,73148.7k $97.0k $97.0k 0.06% Unchanged
22 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 32,55332.6k $64.8k $64.8k 0.00% Reduced -11.1k -11,052
23 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 22,55622.6k $44.9k $44.9k 0.00% New
24 SCHULHOFF & CO INC 0.02% of their portfolio CINCINNATI, OH 22,00022.0k $43.8k $43.8k 0.02% New
25 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 19,99620.0k $40.0k $40.0k 0.00% Reduced -501 -501
26 Cetera Investment Advisers 0.00% of their portfolio SCHAUMBURG, IL 19,26019.3k $38.3k $38.3k 0.00% Added +1.0k +1,000
27 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 16,13216.1k $32.1k $32.1k 0.00% Added +1.6k +1,649
28 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 13,77113.8k $27.4k $27.4k 0.00% New
29 Cubist Systematic Strategies, LLC 0.00% of their portfolio STAMFORD, CT 13,31213.3k $26.5k $26.5k 0.00% Reduced -38.2k -38,205
30 ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio Boston, MA 13,23313.2k $26.0k $26.0k 0.00% New
31 COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio WALTHAM, MA 12,95012.9k $26.0k $26.0k 0.00% New
32 Simplicity Solutions, LLC 0.00% of their portfolio MINNEAPOLIS, MN 11,23411.2k $22.4k $22.4k 0.00% New
33 Bleakley Financial Group, LLC 0.00% of their portfolio PARSIPPANY, NJ 11,23411.2k $22.4k $22.4k 0.00% New
34 Kingsview Wealth Management, LLC 0.00% of their portfolio GRANTS PASS, OR 10,70710.7k $21.3k $21.3k 0.00% Reduced -9.3k -9,293
35 PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 10,35210.4k $20.6k $20.6k 0.00% Unchanged
36 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 7,7867.8k $15.5k $15.5k 0.00% Unchanged
37 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 3,2733.3k $6.0k $6.0k 0.00% Reduced -34.4k -34,402
38 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 3,2003.2k $6.4k $6.4k 0.00% Added +2.7k +2,700
39 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 3,0703.1k $6.1k $6.1k 0.00% Added +3.0k +2,970
40 UBS Group AG 0.00% of their portfolio ZURICH, V8 2,9553.0k $5.9k $5.9k 0.00% Reduced -4.7k -4,695
41 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 2,5082.5k $5.0k $5.0k 0.00% Added +38 +38
42 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 1,9832.0k $3.9k $3.9k 0.00% New
43 NewEdge Advisors, LLC 0.00% of their portfolio NEW ORLEANS, LA 1,7921.8k $3.6k $3.6k 0.00% Unchanged
44 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 1,4021.4k $2.0k $2.0k 0.00% Reduced -940 -940
45 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 500500 $995 $995 0.00% Reduced -3.8k -3,813
46 FMR LLC 0.00% of their portfolio BOSTON, MA 346346 $688 $688 0.00% Added +175 +175
47 Allworth Financial LP 0.00% of their portfolio FOLSOM, CA 200200 $398 $398 0.00% Unchanged
48 Coston, McIsaac & Partners 0.00% of their portfolio BAR HARBOR, ME 144144 $0 $0 0.00% Unchanged
49 CWM, LLC 0.00% of their portfolio OMAHA, NE 9292 $0 $0 0.00% Unchanged
50 Cutler Group LLC / CA 0.00% of their portfolio SAN FRANCISCO, CA 5151 $0 $0 0.00% New
51 West Branch Capital LLC 0.00% of their portfolio AMHERST, MA 2525 $50 $50 0.00% Unchanged
52 Authentikos Wealth Advisory, LLC 0.00% of their portfolio MORGAN HILL, CA 2121 $42 $42 0.00% New
53 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 22 $4 $4 0.00% New
54 Gradient Investments LLC 0.00% of their portfolio ARDEN HILLS, MN 11 $2 $2 0.00% Unchanged
55 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged