Vault-13

PUMA BIOTECHNOLOGY INC PBYI

COM · Common Stock · CUSIP 74587V107 · ISIN US74587V1070

Pharmaceutical company

69 institutional holders -10 vs Q1 2023
26,568,13926.6m shares reported held*
55.9% of all shares outstanding*
$93.8mreported value*
2 new 14 added 29 reduced 13 sold out net sold ≈ $4.7m (-1.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($30.1k this quarter). Holder counts are more reliable. Shares outstanding: 47.5m as of 2023-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.53. Options: 8 managers hold calls ($1.4m notional), 5 hold puts ($230.4k).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

050100Q3 22: 83Q4 22: 89Q1 23: 79Q2 23: 6969Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 202283
Q4 202289
Q1 202379
Q2 202369

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q4 22: 42 bought or addedQ4 22: 39 cut or sold outQ4 22Q1 23: 40 bought or addedQ1 23: 40 cut or sold outQ1 23Q2 23: 16 bought or addedQ2 23: 42 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20224239
Q1 20234040
Q2 20231642

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5mQ3 22 calls: $1.1mQ3 22 puts: $134.0kQ3 22P/C 0.13Q4 22 calls: $870.0kQ4 22 puts: $213.5kQ4 22P/C 0.25Q1 23 calls: $1.1mQ1 23 puts: $229.2kQ1 23P/C 0.20Q2 23 calls: $1.4mQ2 23 puts: $230.4kQ2 23P/C 0.16
Numbers
QuarterCallsPutsP/C
Q3 2022$1.1m$134.0k0.13
Q4 2022$870.0k$213.5k0.25
Q1 2023$1.1m$229.2k0.20
Q2 2023$1.4m$230.4k0.16

Biggest buyers

GSA CAPITAL PARTNERS LLP New +114,698+114.7k
Squarepoint Ops LLC Added +74,137+74.1k
MARSHALL WACE, LLP Added +50,977+51.0k
Assenagon Asset Management S.A. Added +30,127+30.1k
Patriot Financial Group Insurance Agency, LLC Added +29,000+29.0k
Affinity Asset Advisors, LLC Added +25,000+25.0k
Connor, Clark & Lunn Investment Management Ltd. Added +15,822+15.8k
Prospera Financial Services Inc Added +8,376+8.4k
GEODE CAPITAL MANAGEMENT, LLC Added +4,774+4.8k
RICE HALL JAMES & ASSOCIATES, LLC Added +3,537+3.5k

Biggest sellers

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -361,586-361.6k
Eversept Partners, LP Reduced -279,893-279.9k
MILLENNIUM MANAGEMENT LLC Reduced -179,581-179.6k
Cubist Systematic Strategies, LLC Reduced -116,486-116.5k
TWO SIGMA INVESTMENTS, LP Reduced -102,076-102.1k
RENAISSANCE TECHNOLOGIES LLC Reduced -76,900-76.9k
Qube Research & Technologies Ltd Sold out -76,685-76.7k
FMR LLC Reduced -63,924-63.9k
Man Group plc Sold out -62,458-62.5k
683 Capital Management, LLC Sold out -36,500-36.5k

Biggest calls

MILLENNIUM MANAGEMENT LLC Added $931.2k263.8k shares
GROUP ONE TRADING LLC Added $180.0k51.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $113.7k32.2k shares
SIMPLEX TRADING, LLC Reduced $82.0k23.3k shares
CITADEL ADVISORS LLC Added $59.7k16.9k shares
WOLVERINE TRADING, LLC New $37.4k11.0k shares
Patriot Financial Group Insurance Agency, LLC New $2.7k7.7k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $117.2k33.2k shares
SIMPLEX TRADING, LLC Reduced $55.0k15.6k shares
CITADEL ADVISORS LLC Added $38.8k11.0k shares
GROUP ONE TRADING LLC Added $19.4k5.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
AUERBACH ALAN H 13D · may seek influence filed 2026-10-06
Stated purposeThe information set forth or incorporated in Item 3 above is incorporated herein by reference. From time to time, Mr. Auerbach may acquire beneficial ownership of additional shares of Common Stock or other securities of the Issuer by purchase, as compensation from the Issuer, or otherwise, including, but not limited to, awards of restricted Common Shares, options to purchase Common Shares, and restricted stock units for Common Shares, or dispose of some or all of the shares of Common Stock beneficially owned by Mr. Auerbach in the open market or in privately negotiated transactions (which may be with the Issuer or with third parties) on such terms and at such times as Mr. Auerbach may deem advisable. Mr. Auerbach is the President, Chief Executive Officer and a director of the Issuer. In … Full filing
16.0% 8.6m≈ $70.1m 2026-10-06
ACORN BIOVENTURES, L.P. 13G · passive investor +1.3 pts · filed 2025-02-14 8.0% +1.3 pts 3.9m≈ $32.0m 2025-02-14
BlackRock, Inc. 13G · institution filed 2025-04-17 5.6% 2.8m≈ $22.5m 2025-04-17

Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27)

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 0 buyingQ4 21: 4 sellingQ4 21Q1 22: 0 buyingQ1 22: 5 sellingQ2 22: 0 buyingQ2 22: 8 sellingQ2 22Q3 22: 0 buyingQ3 22: 6 sellingQ4 22: 0 buyingQ4 22: 4 sellingQ4 22Q1 23: 0 buyingQ1 23: 5 sellingQ2 23: 0 buyingQ2 23: 7 sellingQ2 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20210—0——
Q4 20210—4$38.9k—
Q1 20220—5$205.1k—
Q2 20220—8$255.0k—
Q3 20220—6$225.0k—
Q4 20220—4$19.1k—
Q1 20230—5$217.3k—
Q2 20230—7$285.3k$285.3k
DateInsiderTradeSharesPrice ValueTheir holding
2023-06-13 WILSON TROY EDWARD Director Sold plan 27,000 $3.45 $93.2k27.0k shares -99%
2023-06-13 Senderowicz Adrian Director Sold plan 27,000 $3.45 $93.2k27.0k shares -100%
2023-06-13 MOYES JAY M Director Sold plan 22,000 $3.45 $75.9k22.0k shares -57%
2023-06-13 MILLER MICHAEL PATRICK Director Sold plan 13,500 $3.45 $46.6k13.5k shares -25%
2023-06-13 Dorval Allison Director Sold plan 10,000 $3.45 $34.5k10.0k shares -37%
2023-06-13 Stuglik Brian M Director Sold plan 9,900 $3.46 $34.3k9.9k shares -24%
2023-06-02 Wong Alvin F Chief Scientific Officer Sold plan 269 $3.45 $928269 shares -<1%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Camber Capital Management LP 0.49% of their portfolio BOSTON, MA 4,235,0004.2m $14.9m $14.9m 0.49% Unchanged
2 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,764,1313.8m $13.3m $13.3m 0.00% Reduced -7.2k -7,214
3 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 2,806,2542.8m $9.9m $9.9m 0.01% Reduced -179.6k -179,581
4 ACADIAN ASSET MANAGEMENT LLC 0.03% of their portfolio Boston, MA 1,874,1231.9m $6.6m $6.6m 0.03% Reduced -736 -736
5 Athyrium Capital Management, LP 4.10% of their portfolio New York, NY 1,792,1141.8m $6.3m $6.3m 4.10% Unchanged
6 RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio NEW YORK, NY 1,758,0131.8m $6.2m $6.2m 0.01% Reduced -76.9k -76,900
7 Eversept Partners, LP 0.62% of their portfolio NEW YORK, NY 1,658,1951.7m $5.9m $5.9m 0.62% Reduced -279.9k -279,893
8 BlackRock Inc. 0.00% of their portfolio New York, NY 1,517,3051.5m $5.4m $5.4m 0.00% Reduced -1.6k -1,637
9 Hillsdale Investment Management Inc. 0.26% of their portfolio Toronto, A6 802,903802.9k $2.8m $2.8m 0.26% Reduced -31.2k -31,200
10 GLOBEFLEX CAPITAL L P 0.22% of their portfolio SAN DIEGO, CA 561,530561.5k $2.0m $2.0m 0.22% Unchanged
11 Kynam Capital Management, LP 0.26% of their portfolio PRINCETON, NJ 473,070473.1k $1.7m $1.7m 0.26% Unchanged
12 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 430,308430.3k $1.5m $1.5m 0.00% Reduced -22.8k -22,797
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 396,396396.4k $1.4m $1.4m 0.00% Added +4.8k +4,774
14 RICE HALL JAMES & ASSOCIATES, LLC 0.07% of their portfolio San Diego, CA 371,034371.0k $1.3m $1.3m 0.07% Added +3.5k +3,537
15 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 344,600344.6k $1.2m $1.2m 0.00% Reduced -36.0k -36,000
16 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 323,603323.6k $1.1m $1.1m 0.00% Reduced -16.3k -16,292
17 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 285,598285.6k $1.0m $1.0m 0.00% Reduced -462 -462
18 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 224,793224.8k $793.5k $793.5k 0.00% Added +51.0k +50,977
19 Assenagon Asset Management S.A. 0.00% of their portfolio SENNINGERBERG, N4 223,321223.3k $788.3k $788.3k 0.00% Added +30.1k +30,127
20 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 219,436219.4k $774.6k $774.6k 0.00% Reduced -16.9k -16,939
21 Affinity Asset Advisors, LLC 0.28% of their portfolio NEW YORK, NY 202,349202.3k $714.3k $714.3k 0.28% Added +25.0k +25,000
22 Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio VANCOUVER, A1 199,767199.8k $705.2k $705.2k 0.00% Added +15.8k +15,822
23 LSV ASSET MANAGEMENT 0.00% of their portfolio CHICAGO, IL 194,551194.6k $687.0k $687.0k 0.00% Unchanged
24 FEDERATED HERMES, INC. 0.00% of their portfolio PITTSBURGH, PA 181,941181.9k $642.3k $642.3k 0.00% Reduced -9.1k -9,122
25 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 166,578166.6k $588.0k $588.0k 0.00% Reduced -22.0k -22,021
26 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 148,400148.4k $523.9k $523.9k 0.01% Unchanged
27 CORNERCAP INVESTMENT COUNSEL INC 0.08% of their portfolio Atlanta, GA 126,963127.0k $448.2k $448.2k 0.08% Added +2.0k +2,044
28 GSA CAPITAL PARTNERS LLP 0.04% of their portfolio LONDON, X0 114,698114.7k $405.0k $405.0k 0.04% New
29 Prospera Financial Services Inc 0.01% of their portfolio Dallas, TX 108,448108.4k $382.8k $382.8k 0.01% Added +8.4k +8,376
30 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 106,073106.1k $374.4k $374.4k 0.00% Reduced -102.1k -102,076
31 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 100,610100.6k $355.2k $355.2k 0.00% Reduced -361.6k -361,586
32 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 90,98791.0k $321.2k $321.2k 0.00% Added +74.1k +74,137
33 XTX Topco Ltd 0.05% of their portfolio LONDON, X0 78,45078.5k $276.9k $276.9k 0.05% Reduced -3.2k -3,169
34 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 73,91473.9k $260.9k $260.9k 0.00% Reduced -90 -90
35 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 72,26872.3k $255.1k $255.1k 0.00% Reduced -1.1k -1,095
36 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 69,59569.6k $245.7k $245.7k 0.00% Reduced -246 -246
37 Patriot Financial Group Insurance Agency, LLC 0.04% of their portfolio Westborough, MA 65,00065.0k $229.4k $229.4k 0.04% Added +29.0k +29,000
38 FMR LLC 0.00% of their portfolio BOSTON, MA 63,91863.9k $225.6k $225.6k 0.00% Reduced -63.9k -63,924
39 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 61,25561.3k $216.0k $216.0k 0.00% Unchanged
40 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 32,90432.9k $116.2k $116.2k 0.00% Reduced -20.2k -20,249
41 Crestline Management, L.P. 0.01% of their portfolio FORT WORTH, TX 32,63932.6k $115.2k $115.2k 0.01% Added +755 +755
42 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 24,23424.2k $85.5k $85.5k 0.00% Unchanged
43 PDT Partners, LLC 0.01% of their portfolio New York, NY 21,94621.9k $77.5k $77.5k 0.01% Unchanged
44 Cubist Systematic Strategies, LLC 0.00% of their portfolio STAMFORD, CT 21,69221.7k $76.6k $76.6k 0.00% Reduced -116.5k -116,486
45 Jump Financial, LLC 0.00% of their portfolio Chicago, IL 19,50019.5k $68.8k $68.8k 0.00% Reduced -15.4k -15,400
46 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 19,45319.5k $68.7k $68.7k 0.00% Unchanged
47 Focus Partners Advisor Solutions, LLC 0.00% of their portfolio SAINT LOUIS, MO 19,22019.2k $67.8k $67.8k 0.00% Unchanged
48 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 17,34017.3k $61.2k $61.2k 0.00% Added +42 +42
49 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 16,40016.4k $57.9k $57.9k 0.00% Unchanged
50 CAXTON ASSOCIATES LP 0.01% of their portfolio NEW YORK, NY 16,24716.2k $57.4k $57.4k 0.01% Reduced -8.4k -8,363
51 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 16,21416.2k $51.9k $51.9k 0.00% Reduced -727 -727
52 COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio WALTHAM, MA 10,74910.7k $38.0k $38.0k 0.00% Unchanged
53 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 5,3505.3k $18.0k $18.0k 0.00% Reduced -5.0k -5,017
54 UBS Group AG 0.00% of their portfolio ZURICH, V8 4,0604.1k $14.3k $14.3k 0.00% Reduced -6.9k -6,865
55 Lindbrook Capital, LLC 0.00% of their portfolio CALABASAS, CA 2,7932.8k $9.9k $9.9k 0.00% Unchanged
56 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 2,0862.1k $7.4k $7.4k 0.00% New
57 GHP Investment Advisors, Inc. 0.00% of their portfolio Denver, CO 1,1701.2k $4.5k $4.5k 0.00% Unchanged
58 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,1031.1k $3.9k $3.9k 0.00% Unchanged
59 Geneos Wealth Management Inc. 0.00% of their portfolio ENGLEWOOD, CO 1,0001.0k $3.5k $3.5k 0.00% Unchanged
60 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 988988 $3.0k $3.0k 0.00% Added +603 +603
61 Aspire Private Capital, LLC 0.00% of their portfolio Cornelius, NC 700700 $2.5k $2.5k 0.00% Unchanged
62 Impact Partnership Wealth, LLC 0.00% of their portfolio MARIETTA, GA 308308 $1.1k $1.1k 0.00% First filing
63 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 289289 $1.0k $1.0k 0.00% Added +17 +17
64 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 242242 $854 $854 0.00% Unchanged
65 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 200200 $706 $706 0.00% Unchanged
66 Cutler Group LLC / CA 0.00% of their portfolio SAN FRANCISCO, CA 200200 $0 $0 0.00% Unchanged
67 TUCKER ASSET MANAGEMENT LLC 0.00% of their portfolio LITTLETON, CO 126126 $445 $445 0.00% Unchanged
68 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 3535 $124 $124 0.00% Reduced -4.8k -4,818
69 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged