PRECISION BIOSCIENCES INC DTIL
COM NEW · Common Stock · CUSIP 74019P207
American gene editing company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersDurham, NC
- Websiteprecisionbiosciences.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 27.6m as of 2026-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.86. Options: 2 managers hold calls ($92.0k notional), 1 hold puts ($98.2k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2024 | 44 |
| Q2 2024 | 48 |
| Q3 2024 | 52 |
| Q4 2024 | 56 |
| Q1 2025 | 49 |
| Q2 2025 | 53 |
| Q3 2025 | 56 |
| Q4 2025 | 69 |
| Q1 2026 | 78 |
| Q2 2026 | 95 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 15 | 12 |
| Q4 2024 | 31 | 19 |
| Q1 2025 | 15 | 21 |
| Q2 2025 | 25 | 15 |
| Q3 2025 | 26 | 17 |
| Q4 2025 | 41 | 16 |
| Q1 2026 | 42 | 24 |
| Q2 2026 | 62 | 27 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $0 | $832 | — |
| Q1 2026 | $112.2k | $0 | 0.00 |
| Q2 2026 | $92.0k | $98.2k | 1.07 |
Biggest buyers
| BlackRock, Inc. | Added | +973.1k |
| MACKENZIE FINANCIAL CORP | New | +481.0k |
| Bleichroeder LP | Added | +355.7k |
| STATE STREET CORP | Added | +354.4k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +333.9k |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | +280.0k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +261.0k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +205.5k |
| JPMORGAN CHASE & CO | Added | +180.4k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +161.8k |
Biggest sellers
| Empery Asset Management, LP | Reduced | -1.2m |
| Octagon Capital Advisors LP | Reduced | -886.7k |
| MARSHALL WACE, LLP | Sold out | -415.7k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -154.6k |
| Alyeska Investment Group, L.P. | Sold out | -138.8k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -69.9k |
| Driehaus Capital Management LLC | Reduced | -48.7k |
| CITADEL ADVISORS LLC | Reduced | -47.4k |
| Schonfeld Strategic Advisors LLC | Sold out | -40.6k |
| SPHERA FUNDS MANAGEMENT LTD. | Sold out | -40.0k |
Biggest calls
| JANE STREET GROUP, LLC | New | $81.7k10.4k shares |
| SIMPLEX TRADING, LLC | New | $10.2k1.3k shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $98.2k12.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Octagon Capital Advisors LP 13G · institution new · filed 2026-02-10 | 10.0% |
| Readout Capital, LP 13G · passive investor +0.5 pts · filed 2025-08-14 | 9.4% |
| Aberdeen Group plc 13G · institution new · filed 2026-01-27 | 8.9% |
| Bleichroeder LP 13G · institution -1.5 pts · filed 2026-02-13 | 8.2% |
| Lynx1 Capital Management LP 13G · passive investor +1.3 pts · filed 2026-07-20 | 5.4% |
| BlackRock, Inc. 13G · institution new · filed 2026-10-27 | 5.0% |
Fell to 5% or below in the last year: Weinstein Benjamin (4.0%, 2026-08-24), Empery Asset Management, LP (5.0%, 2026-07-29), TANG CAPITAL MANAGEMENT LLC (0.0%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 4 | $81.3k | 2 | $29.5k | $4.8k |
| Q1 2025 | 3 | $47.1k | 3 | $271.5k | $271.5k |
| Q2 2025 | 2 | $28.1k | 0 | — | — |
| Q3 2025 | 2 | $20.3k | 1 | $63.2k | $63.2k |
| Q4 2025 | 3 | $33.7k | 3 | $34.9k | $34.9k |
| Q1 2026 | 0 | — | 4 | $412.4k | $412.4k |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 3 | $29.5k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-28 | Frankel Stanley Director | Bought | $6.0k1.0k shares |
| 2026-09-25 | Germano Geno J Director | Bought | $16.4k2.6k shares |
| 2026-09-25 | Brown Melinda Director | Bought | $7.1k1.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Aberdeen Group plc 0.02% of their portfolio | 2.2m $17.5m | Unchanged |
| Bleichroeder LP 2.84% of their portfolio | 2.0m $15.9m | Added +355.7k |
| Octagon Capital Advisors LP 0.97% of their portfolio | 1.4m $10.6m | Reduced -886.7k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.20% of their portfolio | 1.3m $10.6m | Added +280.0k |
| BlackRock, Inc. 0.00% of their portfolio | 1.2m $9.2m | Added +973.1k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.1m $8.8m | Added +205.5k |
| Lynx1 Capital Management LP 0.86% of their portfolio | 950.5k $7.5m | Reduced -34.6k |
| Driehaus Capital Management LLC 0.04% of their portfolio | 946.7k $7.4m | Reduced -48.7k |
| Empery Asset Management, LP 7.05% of their portfolio | 776.1k $6.1m | Reduced -1.2m |
| Affinity Asset Advisors, LLC 0.25% of their portfolio | 646.6k $5.1m | Added +48.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 621.0k $4.9m | Added +333.9k |
| MACKENZIE FINANCIAL CORP 0.00% of their portfolio | 481.0k $3.8m | New |
| STATE STREET CORP 0.00% of their portfolio | 427.3k $3.4m | Added +354.4k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 305.8k $2.4m | Added +261.0k |
| ArrowMark Colorado Holdings LLC 0.09% of their portfolio | 274.1k $2.2m | Added +95.0k |
| Corient Private Wealth LP 0.00% of their portfolio | 245.1k $1.9m | Added +101.2k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 237.9k $1.9m | Reduced -69.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 190.2k $1.5m | Added +114.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 180.5k $1.4m | Added +180.4k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 166.5k $1.3m | Added +10.9k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 161.8k $1.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 139.8k $1.1m | Added +100.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 137.1k $1.1m | Added +93.3k |
| MORGAN STANLEY 0.00% of their portfolio | 130.5k $1.0m | Added +8.3k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 115.9k $911.2k | Added +3.3k |
| Quarry LP 0.12% of their portfolio | 97.9k $769.6k | Added +29.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 86.5k $679.7k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 78.3k $615.6k | Added +58.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 68.6k $539.0k | Reduced -154.6k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 68.6k $538.8k | Reduced -47.4k |
| Jump Financial, LLC 0.00% of their portfolio | 66.8k $525.0k | Added +15.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 59.4k $466.8k | New |
| UBS Group AG 0.00% of their portfolio | 58.7k $461.4k | Reduced -22.4k |
| Trexquant Investment LP 0.00% of their portfolio | 57.2k $449.3k | Added +31.1k |
| Velan Capital Investment Management LP 0.19% of their portfolio | 40.0k $314.4k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 33.3k $261.8k | Added +5.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 32.9k $258.6k | Reduced -31.6k |
| Nuveen, LLC 0.00% of their portfolio | 32.3k $253.8k | New |
| LPL Financial LLC 0.00% of their portfolio | 29.0k $228.0k | Added +16.0k |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 28.7k $225.8k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 27.9k $219.0k | Added +27.6k |
| Invesco Ltd. 0.00% of their portfolio | 27.6k $216.8k | New |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 24.4k $191.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 23.4k $184.0k | New |
| Graham Capital Management, L.P. 0.00% of their portfolio | 21.4k $168.3k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 20.9k $164.3k | New |
| Almanack Investment Partners, LLC. 0.02% of their portfolio | 20.4k $160.6k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 20.1k $158.2k | Added +20.0k |
| Quantinno Capital Management LP 0.00% of their portfolio | 20.1k $158.2k | Added +1.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 20.0k $157.0k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 19.4k $152.3k | New |
| Focus Partners Wealth 0.00% of their portfolio | 19.1k $150.2k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 16.0k $125.8k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 14.5k $114.3k | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 14.1k $110.9k | Reduced -21.5k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 14.1k $110.6k | New |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 14.0k $110.2k | New |
| Verdad Advisers, LP 0.10% of their portfolio | 13.5k $106.3k | New |
| XTX Topco Ltd 0.00% of their portfolio | 12.2k $96.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 12.1k $95.0k | Reduced -890 |
| BARCLAYS PLC 0.00% of their portfolio | 11.3k $89.0k | Added +5.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 11.0k $86.8k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 10.9k $85.5k | Unchanged |
| HBK Sorce Advisory LLC 0.00% of their portfolio | 10.2k $75.9k | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 8.5k $66.8k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 7.5k $59.3k | Reduced -18.2k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 7.1k $55.6k | New |
| Allworth Financial LP 0.00% of their portfolio | 4.8k $37.9k | Added +56 |
| Vivo Capital, LLC 0.00% of their portfolio | 4.7k $36.7k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 2.3k $18.4k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.2k $17.1k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 1.9k $15.3k | Reduced -1.6k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.9k $15.1k | Added +1.7k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 1.9k $15.1k | New |
| NFSG Corp 0.00% of their portfolio | 1.6k $12.6k | Unchanged |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 1.4k $11.0k | New |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 1.0k $7.9k | Unchanged |
| CrossGen Wealth, LLC 0.01% of their portfolio | 1.0k $7.9k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 775 $6.0k | Added +678 |
| Sterling Capital Management LLC 0.00% of their portfolio | 484 $3.8k | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 470 $3.7k | Reduced -8 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 330 $2.6k | New |
| Beacon Financial Strategies CORP 0.00% of their portfolio | 172 $1.4k | Unchanged |
| Fortitude Family Office, LLC 0.00% of their portfolio | 127 $998 | Unchanged |
| SouthState Bank Corp 0.00% of their portfolio | 95 $747 | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 93 $730 | Added +75 |
| FMR LLC 0.00% of their portfolio | 53 $417 | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 18 $141 | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 13 $95 | Unchanged |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 12 $94 | Unchanged |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 10 $79 | Unchanged |
| Investors Research Corp 0.00% of their portfolio | 8 $63 | Unchanged |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 3 $24 | Unchanged |
| TSFG, LLC 0.00% of their portfolio | 3 $0 | Unchanged |
| TD Waterhouse Canada Inc. 0.00% of their portfolio | 1 $8 | Unchanged |