PERSONALIS INC PSNL
COM · Common Stock · CUSIP 71535D106
Company in Menlo Park, United States
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersFremont, CA
- Founded2011
- Websitepersonalis.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.9m this quarter). Holder counts are more reliable. Shares outstanding: 88.8m as of 2025-10-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.52. Options: 3 managers hold calls ($487.5k notional), 5 hold puts ($942.1k).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 81 |
| Q4 2022 | 81 |
| Q1 2023 | 64 |
| Q2 2023 | 67 |
| Q3 2023 | 64 |
| Q4 2023 | 70 |
| Q1 2024 | 72 |
| Q2 2024 | 70 |
| Q3 2024 | 84 |
| Q4 2024 | 108 |
| Q1 2025 | 105 |
| Q2 2025 | 106 |
| Q3 2025 | 109 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 32 | 26 |
| Q1 2024 | 35 | 29 |
| Q2 2024 | 18 | 39 |
| Q3 2024 | 40 | 36 |
| Q4 2024 | 48 | 42 |
| Q1 2025 | 62 | 46 |
| Q2 2025 | 68 | 55 |
| Q3 2025 | 51 | 51 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $481.9k | $510.6k | 1.06 |
| Q1 2025 | $461.6k | $404.3k | 0.88 |
| Q2 2025 | $753.0k | $799.3k | 1.06 |
| Q3 2025 | $487.5k | $942.1k | 1.93 |
Biggest buyers
| T. Rowe Price Investment Management, Inc. | Added | +1.6m |
| KENNEDY CAPITAL MANAGEMENT LLC | Added | +1.3m |
| ARK Investment Management LLC | Added | +802.3k |
| Aberdeen Group plc | Added | +628.5k |
| BlackRock, Inc. | Added | +440.8k |
| GOLDMAN SACHS GROUP INC | Added | +364.3k |
| STATE STREET CORP | Added | +238.8k |
| ORACLE INVESTMENT MANAGEMENT INC | New | +229.4k |
| DIMENSIONAL FUND ADVISORS LP | Added | +188.8k |
| UBS Group AG | Added | +175.8k |
Biggest sellers
| ExodusPoint Capital Management, LP | Sold out | -437.4k |
| Nuveen, LLC | Reduced | -326.9k |
| MORGAN STANLEY | Reduced | -284.4k |
| BANK OF AMERICA CORP /DE/ | Reduced | -188.1k |
| CITIGROUP INC | Reduced | -181.9k |
| ROYAL BANK OF CANADA | Reduced | -145.4k |
| Wellington Shields Capital Management, LLC | Reduced | -134.2k |
| VANGUARD GROUP INC | Reduced | -130.7k |
| Informed Momentum Co LLC | Sold out | -116.2k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -110.2k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $397.7k61.0k shares |
| GROUP ONE TRADING LLC | Reduced | $52.8k8.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $37.0k5.8k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $221.7k34.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $219.0k33.7k shares |
| JANE STREET GROUP, LLC | New | $218.4k33.5k shares |
| CITADEL ADVISORS LLC | Added | $162.3k24.9k shares |
| GROUP ONE TRADING LLC | Added | $120.6k18.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Merck & Co., Inc. 13G · passive investor new · filed 2024-12-23 | 16.5% |
Tempus AI, Inc.
13D · may seek influence
-1.9 pts · filed 2026-07-21
Stated purposeMerger Agreement Following conclusion of confidential preliminary discussions between the Issuer and Tempus, and in response to the Issuer's request for Tempus to submit a proposal, on July 19, 2026, Tempus submitted a non-binding proposal to acquire all of the outstanding Common Stock of the Issuer. On July 20, 2026, Tempus entered into an Agreement and Plan of Merger (the "Merger Agreement") with the Issuer, Aviary Development, Inc., a Delaware corporation and a direct, wholly owned subsidiary of Tempus ("Merger Sub I") and Toucan Development, LLC, a Nevada limited liability company and a direct, wholly owned subsidiary of Tempus ("Merger Sub II" and, together with Merger Sub I, the "Merger Subs"). Pursuant to the Merger Agreement, and upon the terms and subject to the conditions therei… Full filing |
12.6% |
| ARK Investment Management LLC 13G · institution -1.4 pts · filed 2025-05-14 | 8.1% |
| BlackRock, Inc. 13G · institution +2.4 pts · filed 2026-07-29 | 5.9% |
| AMERIPRISE FINANCIAL INC 13G · institution -1.3 pts · filed 2026-08-14 | 5.8% |
Fell to 5% or below in the last year: KEYWELL BRADLEY A (3.5%, 2026-10-28), Deep Track Capital, LP (3.8%, 2026-08-14), Lightspeed Venture Partners Select IV, L.P. (2.0%, 2026-06-10), T. Rowe Price Investment Management, Inc. (4.5%, 2026-04-08), HIRSCHMAN ORIN (3.8%, 2026-01-29)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 4 | $42.2k | — |
| Q1 2024 | 1 | $16.7k | 2 | $1.7k | — |
| Q2 2024 | 0 | — | 3 | $29.5k | — |
| Q3 2024 | 0 | — | 2 | $3.8k | — |
| Q4 2024 | 0 | — | 4 | $207.6k | — |
| Q1 2025 | 0 | — | 2 | $7.1k | — |
| Q2 2025 | 0 | — | 3 | $19.2k | — |
| Q3 2025 | 0 | — | 2 | $7.2k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-07-28 | Tachibana Aaron CFO AND COO | Sold | $4.2k641 shares |
| 2025-07-28 | Chen Richard CHIEF MEDICAL OFFICER AND EVP | Sold | $3.0k452 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| Merck & Co., Inc. 42.02% of their portfolio | 14.0m $91.6m | Unchanged |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 16.53% of their portfolio | 8.2m $53.2m | Unchanged |
| ARK Investment Management LLC 0.31% of their portfolio | 7.9m $51.6m | Added +802.3k |
| BlackRock, Inc. 0.00% of their portfolio | 5.6m $36.8m | Added +440.8k |
| AIGH Capital Management LLC 8.89% of their portfolio | 3.9m $25.4m | Added +168.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.0m $19.6m | Reduced -130.7k |
| T. Rowe Price Investment Management, Inc. 0.01% of their portfolio | 2.9m $18.8m | Added +1.6m |
| Aberdeen Group plc 0.02% of their portfolio | 2.4m $15.6m | Added +628.5k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.28% of their portfolio | 1.9m $12.6m | Added +1.3m |
| Blue Water Life Science Advisors, LP 9.97% of their portfolio | 1.7m $10.9m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $8.7m | Reduced -32.1k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.2m $7.9m | Added +120.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 973.7k $6.3m | Added +188.8k |
| STATE STREET CORP 0.00% of their portfolio | 926.3k $6.0m | Added +238.8k |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 591.0k $3.9m | Reduced -49.4k |
| Amova Asset Management Americas, Inc. 0.04% of their portfolio | 591.0k $3.9m | Reduced -43.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 574.0k $3.7m | Added +364.3k |
| STATE OF MICHIGAN RETIREMENT SYSTEM 0.02% of their portfolio | 493.8k $3.2m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 453.0k $3.0m | Reduced -110.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 393.8k $2.6m | Reduced -6.2k |
| MORGAN STANLEY 0.00% of their portfolio | 342.1k $2.2m | Reduced -284.4k |
| HOWLAND CAPITAL MANAGEMENT LLC 0.08% of their portfolio | 330.7k $2.2m | Added +45.4k |
| Nuveen, LLC 0.00% of their portfolio | 308.7k $2.0m | Reduced -326.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 299.0k $1.9m | Reduced -30.8k |
| UBS Group AG 0.00% of their portfolio | 295.6k $1.9m | Added +175.8k |
| Wellington Shields & Co., LLC 0.50% of their portfolio | 292.5k $1.9m | Unchanged |
| Wellington Shields Capital Management, LLC 0.29% of their portfolio | 292.1k $1.9m | Reduced -134.2k |
| Bruce & Co., Inc. 0.51% of their portfolio | 253.0k $1.6m | Unchanged |
| PERKINS CAPITAL MANAGEMENT INC 1.45% of their portfolio | 252.5k $1.6m | Unchanged |
| ORACLE INVESTMENT MANAGEMENT INC 1.04% of their portfolio | 229.4k $1.5m | New |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.08% of their portfolio | 185.0k $1.2m | Added +92.2k |
| JBF Capital, Inc. 0.15% of their portfolio | 166.1k $1.1m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 158.1k $1.0m | Reduced -1.0k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 154.4k $1.0m | Reduced -145.4k |
| LPL Financial LLC 0.00% of their portfolio | 134.1k $874.3k | Reduced -5.3k |
| Williams Jones Wealth Management, LLC. 0.01% of their portfolio | 134.1k $874.1k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 125.3k $817.0k | Added +6.4k |
| BARCLAYS PLC 0.00% of their portfolio | 114.8k $748.5k | Reduced -25.6k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 112.0k $730.3k | Added +22.3k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.03% of their portfolio | 109.0k $710.4k | Reduced -37.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 101.1k $660.0k | Unchanged |
| XTX Topco Ltd 0.03% of their portfolio | 82.7k $539.3k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 74.1k $483.2k | Reduced -5.2k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 64.7k $421.6k | Reduced -5.3k |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 61.8k $403.2k | Added +13.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 56.8k $370.1k | Reduced -135 |
| TD Asset Management Inc 0.00% of their portfolio | 54.6k $355.9k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 51.4k $320.0k | Reduced -3.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 49.7k $323.8k | Added +20.2k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 48.0k $313.0k | Reduced -2.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 46.9k $306.0k | Added +8.5k |
| GSA CAPITAL PARTNERS LLP 0.03% of their portfolio | 46.2k $301.0k | Reduced -77.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 43.5k $283.9k | Reduced -20.2k |
| Invesco Ltd. 0.00% of their portfolio | 40.2k $262.2k | Added +3.1k |
| Sanctuary Advisors, LLC 0.00% of their portfolio | 40.0k $260.6k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 37.2k $242.4k | Added +4.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 33.9k $221.0k | Reduced -188.1k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 29.8k $194.2k | Reduced -678 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 28.7k $187.1k | Unchanged |
| Green Alpha Advisors, LLC 0.18% of their portfolio | 28.4k $185.1k | Reduced -3.4k |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 25.0k $163.0k | New |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 22.0k $143.4k | Unchanged |
| Squarepoint Ops LLC 0.00% of their portfolio | 18.9k $123.1k | New |
| Atom Investors LP 0.01% of their portfolio | 18.0k $117.6k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.4k $113.8k | Reduced -1.3k |
| Parallel Advisors, LLC 0.00% of their portfolio | 16.5k $107.7k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 16.5k $107.5k | Reduced -9.8k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 15.8k $103.0k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 15.5k $101.3k | Reduced -2.2k |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 14.9k $96.9k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 14.8k $96.5k | Added +8.3k |
| Focus Partners Wealth 0.00% of their portfolio | 13.5k $88.2k | Unchanged |
| FourThought Financial Partners, LLC 0.01% of their portfolio | 13.1k $85.7k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 13.0k $84.6k | Added +1.5k |
| Creative Planning 0.00% of their portfolio | 12.6k $81.9k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 11.7k $76.5k | Reduced -1.8k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 11.6k $75.6k | Added +1.0k |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 10.1k $65.7k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 6.1k $39.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 5.1k $33.4k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 5.0k $26.3k | Added +1.2k |
| Legal & General Group Plc 0.00% of their portfolio | 4.6k $29.8k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 4.2k $27.1k | Reduced -4.3k |
| Sterling Capital Management LLC 0.00% of their portfolio | 3.5k $22.6k | Added +2.1k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.4k $22.4k | Added +16 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.1k $20.4k | Added +3 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.6k $16.9k | Reduced -3.8k |
| FMR LLC 0.00% of their portfolio | 2.4k $15.3k | Added +2.1k |
| CITIGROUP INC 0.00% of their portfolio | 2.3k $14.9k | Reduced -181.9k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 2.1k $14.0k | Added +931 |
| Caitong International Asset Management Co., Ltd 0.01% of their portfolio | 1.9k $12.7k | Reduced -256 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.9k $12.4k | Added +99 |
| AMALGAMATED BANK 0.00% of their portfolio | 1.7k $11.0k | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 1.3k $8.2k | Reduced -562 |
| GPS Wealth Strategies Group, LLC 0.00% of their portfolio | 1.0k $6.5k | Unchanged |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 700 $4.6k | New |
| Ancora Advisors LLC 0.00% of their portfolio | 690 $4.5k | New |
| Physician Wealth Advisors, Inc. 0.00% of their portfolio | 437 $2.9k | Unchanged |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 400 $3.0k | Unchanged |
| Berbice Capital Management LLC 0.02% of their portfolio | 320 $25.8k | New |