PERSONALIS INC PSNL
COM · Common Stock · CUSIP 71535D106
Company in Menlo Park, United States
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersFremont, CA
- Founded2011
- Websitepersonalis.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.3m this quarter). Holder counts are more reliable. Shares outstanding: 88.7m as of 2025-07-29, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.56. Options: 4 managers hold calls ($753.0k notional), 5 hold puts ($799.3k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 81 |
| Q4 2022 | 81 |
| Q1 2023 | 64 |
| Q2 2023 | 67 |
| Q3 2023 | 64 |
| Q4 2023 | 70 |
| Q1 2024 | 72 |
| Q2 2024 | 70 |
| Q3 2024 | 84 |
| Q4 2024 | 108 |
| Q1 2025 | 105 |
| Q2 2025 | 106 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 18 | 34 |
| Q4 2023 | 32 | 26 |
| Q1 2024 | 35 | 29 |
| Q2 2024 | 18 | 39 |
| Q3 2024 | 40 | 36 |
| Q4 2024 | 48 | 42 |
| Q1 2025 | 62 | 46 |
| Q2 2025 | 68 | 55 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $182.6k | $459.5k | 2.52 |
| Q4 2024 | $481.9k | $510.6k | 1.06 |
| Q1 2025 | $461.6k | $404.3k | 0.88 |
| Q2 2025 | $753.0k | $799.3k | 1.06 |
Biggest buyers
| BlackRock, Inc. | Added | +2.2m |
| VANGUARD GROUP INC | Added | +1.8m |
| T. Rowe Price Investment Management, Inc. | New | +1.3m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +851.4k |
| Nuveen, LLC | New | +635.6k |
| Blue Water Life Science Advisors, LP | Added | +500.9k |
| STATE STREET CORP | Added | +492.3k |
| ExodusPoint Capital Management, LP | Added | +403.2k |
| AMERIPRISE FINANCIAL INC | Added | +303.9k |
| NORTHERN TRUST CORP | Added | +302.9k |
Biggest sellers
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -886.0k |
| MARSHALL WACE, LLP | Sold out | -696.3k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -470.7k |
| Qube Research & Technologies Ltd | Reduced | -383.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -327.3k |
| ACADIAN ASSET MANAGEMENT LLC | Reduced | -271.4k |
| JANE STREET GROUP, LLC | Sold out | -247.0k |
| AIGH Capital Management LLC | Reduced | -245.0k |
| Squarepoint Ops LLC | Sold out | -202.5k |
| HRT FINANCIAL LP | Sold out | -177.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $543.8k82.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $137.0k20.9k shares |
| GROUP ONE TRADING LLC | Reduced | $72.2k11.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $347.7k53.0k shares |
| SIMPLEX TRADING, LLC | Added | $266.0k40.6k shares |
| CITADEL ADVISORS LLC | Reduced | $138.4k21.1k shares |
| GROUP ONE TRADING LLC | Reduced | $47.2k7.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Merck & Co., Inc. 13G · passive investor new · filed 2024-12-23 | 16.5% |
Tempus AI, Inc.
13D · may seek influence
-1.9 pts · filed 2026-07-21
Stated purposeMerger Agreement Following conclusion of confidential preliminary discussions between the Issuer and Tempus, and in response to the Issuer's request for Tempus to submit a proposal, on July 19, 2026, Tempus submitted a non-binding proposal to acquire all of the outstanding Common Stock of the Issuer. On July 20, 2026, Tempus entered into an Agreement and Plan of Merger (the "Merger Agreement") with the Issuer, Aviary Development, Inc., a Delaware corporation and a direct, wholly owned subsidiary of Tempus ("Merger Sub I") and Toucan Development, LLC, a Nevada limited liability company and a direct, wholly owned subsidiary of Tempus ("Merger Sub II" and, together with Merger Sub I, the "Merger Subs"). Pursuant to the Merger Agreement, and upon the terms and subject to the conditions therei… Full filing |
12.6% |
| ARK Investment Management LLC 13G · institution -1.4 pts · filed 2025-05-14 | 8.1% |
| BlackRock, Inc. 13G · institution +2.4 pts · filed 2026-07-29 | 5.9% |
| AMERIPRISE FINANCIAL INC 13G · institution -1.3 pts · filed 2026-08-14 | 5.8% |
Fell to 5% or below in the last year: KEYWELL BRADLEY A (3.5%, 2026-10-28), Deep Track Capital, LP (3.8%, 2026-08-14), Lightspeed Venture Partners Select IV, L.P. (2.0%, 2026-06-10), T. Rowe Price Investment Management, Inc. (4.5%, 2026-04-08), HIRSCHMAN ORIN (3.8%, 2026-01-29), Red Sky Ventures LLC (4.7%, 2025-11-13)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 2 | $2.6k | — |
| Q4 2023 | 0 | — | 4 | $42.2k | — |
| Q1 2024 | 1 | $16.7k | 2 | $1.7k | — |
| Q2 2024 | 0 | — | 3 | $29.5k | — |
| Q3 2024 | 0 | — | 2 | $3.8k | — |
| Q4 2024 | 0 | — | 4 | $207.6k | — |
| Q1 2025 | 0 | — | 2 | $7.1k | — |
| Q2 2025 | 0 | — | 3 | $19.2k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-05-16 | Moore Stephen Michael SVP and Chief Legal Officer | Sold | $8.3k1.7k shares |
| 2025-05-16 | Tachibana Aaron CFO AND COO | Sold | $6.4k1.3k shares |
| 2025-05-16 | Chen Richard CHIEF MEDICAL OFFICER AND EVP | Sold | $4.5k910 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Merck & Co., Inc. 45.18% of their portfolio | 14.0m $92.1m | Unchanged |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 22.42% of their portfolio | 8.2m $53.5m | Unchanged |
| ARK Investment Management LLC 0.34% of their portfolio | 7.1m $46.6m | Reduced -80.3k |
| BlackRock, Inc. 0.00% of their portfolio | 5.2m $34.1m | Added +2.2m |
| AIGH Capital Management LLC 11.46% of their portfolio | 3.7m $24.4m | Reduced -245.0k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.1m $20.6m | Added +1.8m |
| Aberdeen Group plc 0.02% of their portfolio | 1.8m $11.5m | Added +54.7k |
| Blue Water Life Science Advisors, LP 8.70% of their portfolio | 1.7m $11.0m | Added +500.9k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.4m $9.0m | Added +851.4k |
| T. Rowe Price Investment Management, Inc. 0.01% of their portfolio | 1.3m $8.3m | New |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.1m $7.2m | Added +219.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 784.9k $5.1m | Added +149.8k |
| STATE STREET CORP 0.00% of their portfolio | 687.6k $4.5m | Added +492.3k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.10% of their portfolio | 653.4k $4.3m | Added +49.1k |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 640.4k $4.2m | Reduced -35.6k |
| Nuveen, LLC 0.00% of their portfolio | 635.6k $4.2m | New |
| Amova Asset Management Americas, Inc. 0.04% of their portfolio | 634.3k $4.2m | Reduced -41.7k |
| MORGAN STANLEY 0.00% of their portfolio | 626.5k $4.1m | Added +66.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 563.2k $3.7m | Reduced -470.7k |
| STATE OF MICHIGAN RETIREMENT SYSTEM 0.02% of their portfolio | 493.8k $3.2m | Unchanged |
| ExodusPoint Capital Management, LP 0.03% of their portfolio | 437.4k $2.9m | Added +403.2k |
| Wellington Shields Capital Management, LLC 0.47% of their portfolio | 426.3k $2.8m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 400.0k $2.6m | Added +302.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 329.9k $2.2m | Added +303.9k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 299.8k $2.0m | Added +221.4k |
| Wellington Shields & Co., LLC 0.54% of their portfolio | 292.5k $1.9m | Unchanged |
| HOWLAND CAPITAL MANAGEMENT LLC 0.08% of their portfolio | 285.3k $1.9m | Added +2.5k |
| Bruce & Co., Inc. 0.54% of their portfolio | 253.0k $1.7m | Unchanged |
| PERKINS CAPITAL MANAGEMENT INC 1.67% of their portfolio | 252.5k $1.7m | Reduced -4.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 222.0k $1.5m | Added +21.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 209.7k $1.4m | Reduced -74.8k |
| CITIGROUP INC 0.00% of their portfolio | 184.2k $1.2m | Added +183.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 159.1k $1.0m | Added +136.2k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.03% of their portfolio | 146.6k $961.8k | Reduced -7.5k |
| BARCLAYS PLC 0.00% of their portfolio | 140.4k $920.9k | Added +54.4k |
| LPL Financial LLC 0.00% of their portfolio | 139.4k $914.4k | Reduced -8.5k |
| Williams Jones Wealth Management, LLC. 0.01% of their portfolio | 134.1k $879.5k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.06% of their portfolio | 124.1k $814.0k | Reduced -20.6k |
| UBS Group AG 0.00% of their portfolio | 119.8k $786.0k | Added +73.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 118.9k $780.2k | New |
| Informed Momentum Co LLC 0.12% of their portfolio | 116.2k $762.0k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 101.1k $664.0k | Added +16.1k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.05% of their portfolio | 92.8k $609.0k | Added +37.3k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 89.7k $588.2k | Added +22.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 79.3k $520.0k | Added +75.6k |
| Polar Asset Management Partners Inc. 0.01% of their portfolio | 71.7k $470.4k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 69.9k $458.7k | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 68.7k $450.5k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 63.8k $418.5k | Reduced -886.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 56.9k $373.2k | Reduced -53.3k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 54.6k $373.1k | Added +15.4k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 50.0k $328.0k | Added +10.0k |
| Man Group plc 0.00% of their portfolio | 49.4k $323.9k | New |
| Mach-1 Financial Group, LLC 0.09% of their portfolio | 48.8k $320.3k | New |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 47.9k $314.5k | Added +26.5k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 39.6k $260.0k | Reduced -327.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 39.2k $256.0k | Reduced -271.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 38.5k $252.3k | Added +37.9k |
| Invesco Ltd. 0.00% of their portfolio | 37.1k $243.4k | Added +23.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 32.9k $215.6k | New |
| Green Alpha Advisors, LLC 0.20% of their portfolio | 31.8k $208.9k | Reduced -5.4k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 30.5k $199.9k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 29.5k $193.5k | Added +24.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 28.7k $188.3k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 26.3k $172.6k | New |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 25.2k $165.3k | New |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 22.0k $144.3k | Unchanged |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 19.2k $126.2k | Reduced -383.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 18.8k $123.0k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 17.7k $116.4k | Added +36 |
| Parallel Advisors, LLC 0.00% of their portfolio | 16.5k $108.4k | Unchanged |
| Mariner, LLC 0.00% of their portfolio | 16.4k $107.5k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 15.8k $103.6k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 14.0k $92.1k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 13.6k $89.1k | New |
| Focus Partners Wealth 0.00% of their portfolio | 13.5k $88.7k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 11.5k $75.3k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 10.6k $69.5k | Unchanged |
| Alpha Wealth Funds, LLC 0.06% of their portfolio | 10.0k $66.0k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 8.5k $55.6k | Reduced -7.0k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 6.5k $42.3k | Added +5.2k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.4k $42.1k | Reduced -40.6k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 5.1k $33.6k | New |
| Legal & General Group Plc 0.00% of their portfolio | 4.6k $30.0k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 3.8k $24.9k | Added +1.4k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.4k $22.4k | Added +459 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.1k $20.5k | New |
| Caitong International Asset Management Co., Ltd 0.01% of their portfolio | 2.2k $14.4k | Added +1.6k |
| Larson Financial Group LLC 0.00% of their portfolio | 1.9k $12.3k | Reduced -43 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 1.8k $12.0k | Reduced -203 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.8k $11.9k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 1.7k $11.0k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 1.4k $8.9k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 1.2k $7.9k | Reduced -4.9k |
| GPS Wealth Strategies Group, LLC 0.00% of their portfolio | 1.0k $6.6k | New |
| US BANCORP \DE\ 0.00% of their portfolio | 900 $5.9k | Reduced -100 |
| Physician Wealth Advisors, Inc. 0.00% of their portfolio | 437 $2.9k | New |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 400 $3.0k | Unchanged |
| FMR LLC 0.00% of their portfolio | 211 $1.4k | New |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 165 $1.1k | New |