PEPGEN INC PEPG
COM · Common Stock · CUSIP 713317105
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 69.3m as of 2026-08-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.80. Options: 2 managers hold calls ($57.1k notional), 2 hold puts ($42.7k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 43 |
| Q4 2022 | 47 |
| Q1 2023 | 46 |
| Q2 2023 | 45 |
| Q3 2023 | 44 |
| Q4 2023 | 43 |
| Q1 2024 | 57 |
| Q2 2024 | 62 |
| Q3 2024 | 63 |
| Q4 2024 | 62 |
| Q1 2025 | 73 |
| Q2 2025 | 53 |
| Q3 2025 | 73 |
| Q4 2025 | 88 |
| Q1 2026 | 94 |
| Q2 2026 | 72 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 31 | 26 |
| Q4 2024 | 29 | 27 |
| Q1 2025 | 38 | 28 |
| Q2 2025 | 22 | 44 |
| Q3 2025 | 52 | 31 |
| Q4 2025 | 57 | 28 |
| Q1 2026 | 51 | 47 |
| Q2 2026 | 28 | 54 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $5.9m | $846.0k | 0.14 |
| Q4 2025 | $5.3m | $1.8m | 0.33 |
| Q1 2026 | $1.9m | $209.0k | 0.11 |
| Q2 2026 | $57.1k | $42.7k | 0.75 |
Biggest buyers
| RENAISSANCE TECHNOLOGIES LLC | Added | +1.5m |
| ADAR1 Capital Management, LLC | Added | +983.4k |
| GSA CAPITAL PARTNERS LLP | Added | +814.6k |
| MARSHALL WACE, LLP | Added | +568.4k |
| CITADEL ADVISORS LLC | Added | +450.5k |
| Squarepoint Ops LLC | Added | +382.5k |
| Rosalind Advisors, Inc. | New | +350.0k |
| DIADEMA PARTNERS LP | Added | +222.4k |
| XTX Topco Ltd | Added | +114.2k |
| Persistent Asset Partners Ltd | Added | +56.9k |
Biggest sellers
| Kalehua Capital Management LLC | Sold out | -1.7m |
| Woodline Partners LP | Sold out | -1.3m |
| Pictet Asset Management Holding SA | Sold out | -1.3m |
| AWM Investment Company, Inc. | Reduced | -1.2m |
| MORGAN STANLEY | Reduced | -950.1k |
| Nantahala Capital Management, LLC | Sold out | -681.2k |
| Qube Research & Technologies Ltd | Reduced | -607.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -366.8k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -292.4k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -162.7k |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $38.7k21.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $18.4k10.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $23.6k13.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $19.1k10.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence filed 2025-09-30 | 29.2% |
| Oxford Science Enterprises plc 13G · passive investor filed 2025-10-01 | 7.2% |
| Commodore Capital LP 13G · passive investor +1.4 pts · filed 2026-05-15 | 6.5% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -0.1 pts · filed 2026-05-15 | 5.0% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (3.0%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 2 | $5.0k | — |
| Q2 2025 | 2 | $71.7k | 0 | — | — |
| Q3 2025 | 1 | $30.0m | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 3 | $57.6k | — |
| Q2 2026 | 0 | — | 1 | $1.7k | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-05-21 | Kasraian Kasra Chief Technical Officer | Sold | $1.7k1.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.31% of their portfolio | 20.1m $36.1m | Unchanged |
| Commodore Capital LP 0.48% of their portfolio | 4.5m $8.1m | Unchanged |
| VIKING GLOBAL INVESTORS LP 0.02% of their portfolio | 3.5m $6.3m | Unchanged |
| Laurion Capital Management LP 0.36% of their portfolio | 2.8m $5.0m | Unchanged |
| ADAR1 Capital Management, LLC 0.22% of their portfolio | 2.6m $4.7m | Added +983.4k |
| Vivo Capital, LLC 0.38% of their portfolio | 2.3m $4.2m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.9m $3.5m | Reduced -1.8k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.8m $3.2m | Reduced -292.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.5m $2.7m | Added +1.5m |
| BlackRock, Inc. 0.00% of their portfolio | 1.3m $2.3m | Added +26.5k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 867.0k $1.6m | Added +568.4k |
| GSA CAPITAL PARTNERS LLP 0.10% of their portfolio | 852.9k $1.5m | Added +814.6k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 658.4k $1.2m | Added +450.5k |
| AWM Investment Company, Inc. 0.09% of their portfolio | 600.0k $1.1m | Reduced -1.2m |
| MONIMUS CAPITAL MANAGEMENT, LP 0.27% of their portfolio | 587.7k $1.1m | Reduced -11.0k |
| Squarepoint Ops LLC 0.00% of their portfolio | 529.1k $952.3k | Added +382.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 523.5k $942.8k | Reduced -12.5k |
| Creek Drive Management Group LLC 0.50% of their portfolio | 450.0k $810.0k | Unchanged |
| Ikarian Capital, LLC 0.13% of their portfolio | 447.2k $804.9k | Unchanged |
| DIADEMA PARTNERS LP 0.24% of their portfolio | 373.3k $671.9k | Added +222.4k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.01% of their portfolio | 366.1k $659.1k | Added +14.8k |
| Rosalind Advisors, Inc. 0.24% of their portfolio | 350.0k $630.0k | New |
| Driehaus Capital Management LLC 0.00% of their portfolio | 279.9k $503.8k | Unchanged |
| Boxer Capital Management, LLC 0.04% of their portfolio | 272.9k $491.2k | Unchanged |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 261.5k $470.7k | Added +1.8k |
| XTX Topco Ltd 0.01% of their portfolio | 245.3k $441.6k | Added +114.2k |
| STATE STREET CORP 0.00% of their portfolio | 229.4k $412.9k | Unchanged |
| Artia Global Partners LP 0.07% of their portfolio | 205.3k $369.6k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 172.4k $310.3k | Reduced -25.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 168.1k $302.6k | Added +29.5k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 112.1k $201.7k | Added +42.9k |
| UBS Group AG 0.00% of their portfolio | 110.7k $199.2k | Added +16.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 98.7k $177.7k | Reduced -6.2k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 98.6k $177.4k | Reduced -607.9k |
| RBF Capital, LLC 0.01% of their portfolio | 95.0k $171.1k | Unchanged |
| Persistent Asset Partners Ltd 0.05% of their portfolio | 95.0k $171.0k | Added +56.9k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 93.7k $168.7k | Added +50.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 75.4k $135.7k | Reduced -366.8k |
| Rangeley Capital, LLC 0.12% of their portfolio | 70.0k $126.0k | Added +1.9k |
| Verdad Advisers, LP 0.12% of their portfolio | 66.9k $120.4k | Added +12.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 66.3k $119.3k | Reduced -115.4k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 54.1k $97.3k | Reduced -162.7k |
| MORGAN STANLEY 0.00% of their portfolio | 48.8k $87.9k | Reduced -950.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 42.6k $76.7k | Unchanged |
| Quadrature Capital Ltd 0.00% of their portfolio | 40.9k $73.7k | Reduced -117.9k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 39.7k $71.5k | Reduced -26.3k |
| Rathbones Group PLC 0.00% of their portfolio | 32.0k $57.6k | Reduced -32.0k |
| READYSTATE ASSET MANAGEMENT LP 0.00% of their portfolio | 28.4k $51.1k | Reduced -86.7k |
| Bronte Capital Management Pty Ltd. 0.00% of their portfolio | 17.8k $32.0k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 17.7k $31.9k | Unchanged |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 17.6k $31.7k | New |
| Aigen Investment Management, LP 0.01% of their portfolio | 12.9k $23.2k | New |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 11.0k $19.8k | Reduced -1.2k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 9.7k $17.5k | Reduced -33.8k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 5.6k $10.0k | Added +17 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 5.1k $9.0k | Reduced -129 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 4.5k $8.1k | Added +2.5k |
| BARCLAYS PLC 0.00% of their portfolio | 4.4k $7.9k | Reduced -40.7k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.1k $5.6k | Reduced -492 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 2.7k $4.9k | Reduced -61.0k |
| FMR LLC 0.00% of their portfolio | 1.7k $3.0k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 1.6k $2.9k | Reduced -879 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.4k $2.6k | Reduced -106 |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 869 $1.0k | Reduced -63.7k |
| Bare Financial Services, Inc 0.00% of their portfolio | 327 $589 | Added +225 |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 326 $554 | Unchanged |
| Rialto Wealth Management, LLC 0.00% of their portfolio | 318 $573 | New |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 195 $351 | Unchanged |
| Cornerstone Financial Management LLC 0.00% of their portfolio | 121 $218 | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 61 $0 | Reduced -921 |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 60 $108 | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 13 $23 | New |