PARABILIS MEDICINES INC PBLS
COM · Common Stock · CUSIP 698955101
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $27.39.
Biggest buyers
| RA CAPITAL MANAGEMENT, L.P. | New | +28.9m |
| FMR LLC | New | +10.3m |
| ARCH Venture Management, LLC | New | +6.4m |
| venBio Partners LLC | New | +5.3m |
| Alphabet Inc. | New | +4.9m |
| Nextech Invest Ltd. | New | +4.7m |
| Cormorant Asset Management, LP | New | +4.6m |
| REGENERON PHARMACEUTICALS, INC. | New | +4.2m |
| Siren, L.L.C. | New | +3.0m |
| Frazier Life Sciences Management, L.P. | New | +1.9m |
Biggest sellers
| None |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
new · filed 2026-06-18
Stated purposeThe Reporting Persons acquired the voting common stock reported herein for investment purposes and not with an intent, purpose or effect of changing control of the Issuer. The Reporting Persons may, from time to time, acquire additional equity securities or debt securities of the Issuer, which debt securities may be convertible or non-convertible, secured or unsecured, and could involve the monetization of potential revenue streams deriving from development-stage or commercial programs of the Issuer, or dispose of Issuer securities they beneficially own, on the open market or in private transactions or otherwise (including by means of 10b5-1 programs), consistent with their investment purposes and in amounts, on such terms and at such times as to be determined by the Reporting Persons base… Full filing |
23.8% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 8.5% |
| ARCH Venture Fund XII, L.P. 13G · exempt (held before listing) new · filed 2026-08-14 | 5.3% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 2 | $424.5m | 0 | — | — |
| Q3 2026 | 1 | $6.9m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-22 | RA Capital Healthcare Fund LP +4 Director · See footnotes | Bought | $1.4m47.2k shares |
| 2026-07-21 | RA Capital Healthcare Fund LP +4 Director · See footnotes | Bought | $1.9m65.9k shares |
| 2026-07-20 | RA Capital Healthcare Fund LP +4 Director · See footnotes | Bought | $3.6m131.4k shares |
| 2026-06-15 | SEBULSKY ALAN Director · By Apothecary Capital LLC | Bought | $240.2k9.1k shares |
| 2026-06-12 | SEBULSKY ALAN Director · By Apothecary Capital LLC | Bought | $233.4k8.4k shares |
| 2026-06-11 | RA Capital Healthcare Fund LP +4 Director · See footnotes | Bought | $423.8m21.2m shares |
| 2026-06-11 | Soleus Capital, LLC +8 10% owner · See footnote | Bought | $10.0m500.0k shares |
| 2026-06-11 | SEBULSKY ALAN Director · By Apothecary Capital LLC | Bought | $250.0k12.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 6.88% of their portfolio | 28.9m $791.9m | New |
| FMR LLC 0.01% of their portfolio | 10.3m $281.7m | New |
| ARCH Venture Management, LLC 15.95% of their portfolio | 6.4m $175.5m | New |
| venBio Partners LLC 27.75% of their portfolio | 5.3m $144.1m | New |
| Alphabet Inc. 0.14% of their portfolio | 4.9m $134.6m | New |
| Nextech Invest Ltd. 6.06% of their portfolio | 4.7m $127.6m | New |
| Cormorant Asset Management, LP 6.47% of their portfolio | 4.6m $126.3m | New |
| REGENERON PHARMACEUTICALS, INC. 64.35% of their portfolio | 4.2m $114.0m | New |
| Siren, L.L.C. 1.66% of their portfolio | 3.0m $81.9m | New |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.38% of their portfolio | 2.4m $64.8m | Not comparable |
| Jupiter Topco LLC 0.03% of their portfolio | 2.3m $62.7m | First filing |
| Frazier Life Sciences Management, L.P. 1.14% of their portfolio | 1.9m $52.6m | New |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.54% of their portfolio | 1.9m $51.5m | New |
| General Catalyst Group Management, LLC 23.24% of their portfolio | 1.6m $43.8m | New |
| GENERAL ATLANTIC, L.P. 1.45% of their portfolio | 1.5m $42.1m | New |
| Soleus Capital Management, L.P. 1.38% of their portfolio | 1.5m $40.1m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.3m $35.6m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.2m $31.7m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.0m $30.4m | New |
| Foresite Capital Management VI LLC 4.26% of their portfolio | 999.0k $27.3m | New |
| Catalio Capital Management, LP 4.24% of their portfolio | 824.0k $22.6m | New |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 810.3k $22.2m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 751.9k $20.6m | New |
| Casdin Capital, LLC 0.88% of their portfolio | 645.7k $17.7m | New |
| Venrock Adviser, LLC 0.52% of their portfolio | 625.0k $17.1m | New |
| Rock Springs Capital Management LP 0.77% of their portfolio | 578.0k $15.8m | New |
| SAMSARA BIOCAPITAL, LLC 1.25% of their portfolio | 556.0k $15.2m | New |
| Logos Global Management LP 0.62% of their portfolio | 525.0k $14.4m | New |
| BAKER BROS. ADVISORS LP 0.07% of their portfolio | 500.0k $13.7m | New |
| Bellevue Group AG 0.29% of their portfolio | 500.0k $13.7m | New |
| MARSHALL WACE, LLP 0.01% of their portfolio | 445.4k $12.2m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 381.5k $10.4m | New |
| ICONIQ Capital, LLC 0.28% of their portfolio | 350.0k $9.6m | New |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 296.0k $8.1m | New |
| Kynam Capital Management, LP 0.38% of their portfolio | 250.0k $6.8m | New |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 246.2k $6.7m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 174.8k $4.8m | New |
| Driehaus Capital Management LLC 0.02% of their portfolio | 100.0k $2.7m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 99.4k $2.7m | New |
| TD Asset Management Inc 0.00% of their portfolio | 77.0k $2.1m | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 48.5k $1.3m | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 44.0k $1.2m | New |
| UBS Group AG 0.00% of their portfolio | 38.7k $1.1m | New |
| WINTON GROUP Ltd 0.03% of their portfolio | 34.9k $955.2k | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 27.8k $760.9k | New |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 24.3k $664.1k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 22.7k $621.0k | New |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 22.6k $617.6k | New |
| Ghisallo Capital Management LLC 0.01% of their portfolio | 20.0k $547.4k | New |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 19.2k $525.5k | New |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 11.7k $321.0k | New |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 10.0k $273.7k | New |
| Burkehill Global Management, LP 0.01% of their portfolio | 10.0k $273.7k | New |
| SEVEN GRAND MANAGERS, LLC 0.01% of their portfolio | 10.0k $273.7k | New |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 9.7k $265.2k | New |
| Scientech Research LLC 0.21% of their portfolio | 9.6k $261.8k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 8.7k $239.2k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 8.3k $225.9k | New |
| Persistent Asset Partners Ltd 0.04% of their portfolio | 4.1k $113.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.1k $56.7k | New |
| CITIGROUP INC 0.00% of their portfolio | 1.9k $51.2k | New |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 1.6k $43.8k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.2k $31.5k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 920 $25.2k | New |
| Parallel Advisors, LLC 0.00% of their portfolio | 550 $15.1k | New |
| Rialto Wealth Management, LLC 0.00% of their portfolio | 508 $13.9k | New |
| Longaeva Partners L.P. 0.00% of their portfolio | 500 $13.7k | New |
| Bell Investment Advisors, Inc 0.00% of their portfolio | 451 $12.3k | New |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 261 $7.1k | New |
| MORGAN STANLEY 0.00% of their portfolio | 200 $5.5k | New |
| Atlantic Union Bankshares Corp 0.00% of their portfolio | 180 $4.9k | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 103 $3.0k | New |
| Allworth Financial LP 0.00% of their portfolio | 100 $2.7k | New |
| Avion Wealth 0.00% of their portfolio | 69 $1.0k | New |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 60 $1.6k | New |
| Physician Wealth Advisors, Inc. 0.00% of their portfolio | 59 $1.6k | New |
| North Star Investment Management Corp. 0.00% of their portfolio | 52 $1.4k | New |
| Cornerstone Financial Management LLC 0.00% of their portfolio | 29 $794 | New |
| Bogart Wealth, LLC 0.00% of their portfolio | 19 $520 | New |