PALVELLA THERAPEUTICS INC NE PVLA
COM · Common Stock · CUSIP 697947109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWayne, PA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($688.3k this quarter). Holder counts are more reliable. Shares outstanding: 14.4m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $152.32. Options: 6 managers hold calls ($37.9m notional), 5 hold puts ($37.0m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2024 | 34 |
| Q1 2025 | 42 |
| Q2 2025 | 66 |
| Q3 2025 | 100 |
| Q4 2025 | 140 |
| Q1 2026 | 180 |
| Q2 2026 | 197 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2025 | 23 | 11 |
| Q2 2025 | 45 | 11 |
| Q3 2025 | 66 | 27 |
| Q4 2025 | 91 | 42 |
| Q1 2026 | 123 | 52 |
| Q2 2026 | 124 | 62 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $984.2k | $319.7k | 0.32 |
| Q4 2025 | $20.2m | $10.2m | 0.51 |
| Q1 2026 | $53.5m | $14.2m | 0.27 |
| Q2 2026 | $37.9m | $37.0m | 0.98 |
Biggest buyers
| JENNISON ASSOCIATES LLC | Added | +320.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +236.3k |
| BlackRock, Inc. | Added | +231.5k |
| STATE STREET CORP | Added | +194.2k |
| ORBIMED ADVISORS LLC | Added | +157.8k |
| Bellevue Group AG | New | +155.0k |
| FRONTIER CAPITAL MANAGEMENT CO LLC | Added | +104.8k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +70.6k |
| EMERALD ADVISERS, LLC | Added | +68.0k |
| PRIMECAP MANAGEMENT CO/CA/ | Added | +61.2k |
Biggest sellers
| BVF INC/IL | Reduced | -288.2k |
| First Light Asset Management, LLC | Reduced | -208.9k |
| Artisan Partners Limited Partnership | Sold out | -193.8k |
| Alyeska Investment Group, L.P. | Reduced | -177.7k |
| Point72 Asset Management, L.P. | Sold out | -88.2k |
| Avidity Partners Management LP | Reduced | -70.0k |
| Ikarian Capital, LLC | Sold out | -64.6k |
| Balyasny Asset Management L.P. | Reduced | -52.2k |
| Apis Capital Advisors, LLC | Reduced | -50.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -41.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $18.4m120.6k shares |
| ORBIMED ADVISORS LLC | Reduced | $6.1m40.0k shares |
| CITADEL ADVISORS LLC | Added | $4.6m30.4k shares |
| Caption Management, LLC | Reduced | $4.6m30.0k shares |
| JANE STREET GROUP, LLC | Reduced | $4.1m26.8k shares |
| GROUP ONE TRADING LLC | Reduced | $15.3k100 shares |
Biggest puts
| Caption Management, LLC | Added | $21.4m140.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $11.7m76.6k shares |
| CITADEL ADVISORS LLC | Added | $2.0m13.3k shares |
| GROUP ONE TRADING LLC | New | $1.5m10.0k shares |
| JANE STREET GROUP, LLC | Reduced | $320.9k2.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Kaupinen Wes
13D · may seek influence
new · filed 2024-12-20
Stated purposeMr. Kaupinen serves as President and Chief Executive Officer of the Issuer and is a member of the board of directors of the Issuer, and, in such capacity, may have influence over the corporate activities of the Issuer, including activities which may relate to items described in subparagraphs (a) through (j) of Item 4 of Schedule 13D. Subject to the Lock-up Agreement described in Item 6 of this Schedule 13D and the Issuer's Insider Trading Policy, each Reporting Persons may from time to time purchase additional securities of the Issuer either in the open market or in privately negotiated transactions, depending upon such Reporting Person's evaluation of the Issuer's business, prospects and financial condition, the market for such securities, other opportunities available to such Reporting P… Full filing |
14.6% |
| JENNISON ASSOCIATES LLC 13G · institution +1.0 pts · filed 2026-10-28 | 7.7% |
| SUVRETTA CAPITAL MANAGEMENT, LLC 13G · passive investor -1.2 pts · filed 2025-11-13 | 7.4% |
| PRUDENTIAL FINANCIAL INC 13G · institution new · filed 2026-08-10 | 6.7% |
| Frazier Life Sciences Public Fund, L.P. 13G · passive investor +1.1 pts · filed 2026-02-13 | 6.0% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-29 | 5.7% |
| First Light Asset Management, LLC 13G · institution -2.2 pts · filed 2026-08-14 | 5.3% |
Fell to 5% or below in the last year: BIOTECHNOLOGY VALUE FUND L P (4.7%, 2026-08-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 1 | $51.7k | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $100.8k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $786.0k | $786.0k |
| Q1 2026 | 2 | $850.0k | 1 | $1.3m | $1.3m |
| Q2 2026 | 0 | — | 1 | $1.5m | $1.5m |
| Q3 2026 | 0 | — | 3 | $6.2m | $6.1m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-16 | Goin Kathleen Chief Operating Officer | Sold plan | $654.9k4.3k shares |
| 2026-09-15 | JENKINS GEORGE M Director | Sold plan | $266.8k1.8k shares |
| 2026-09-14 | JENKINS GEORGE M Director | Sold plan | $2.0m13.4k shares |
| 2026-09-11 | JENKINS GEORGE M Director | Sold plan | $1.9m12.4k shares |
| 2026-09-02 | KIRITSY CHRISTOPHER P Director | Sold | $49.1k313 shares |
| 2026-08-19 | Goin Kathleen Chief Operating Officer | Sold plan | $654.8k4.3k shares |
| 2026-07-15 | Goin Kathleen Chief Operating Officer | Sold plan | $642.2k4.3k shares |
| 2026-06-17 | Goin Kathleen Chief Operating Officer | Sold plan | $476.4k4.3k shares |
| 2026-05-20 | Goin Kathleen Chief Operating Officer | Sold plan | $475.6k4.3k shares |
| 2026-04-15 | Goin Kathleen Chief Operating Officer | Sold plan | $547.4k4.3k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| MONTANOVA CAPITAL, LLC 3.65% of their portfolio | 1.1m $173.5m | Reduced -18.1k |
| JENNISON ASSOCIATES LLC 0.09% of their portfolio | 960.6k $146.8m | Added +320.0k |
| BlackRock, Inc. 0.00% of their portfolio | 918.4k $140.3m | Added +231.5k |
| Frazier Life Sciences Management, L.P. 2.94% of their portfolio | 882.4k $134.8m | Unchanged |
| First Light Asset Management, LLC 7.17% of their portfolio | 771.9k $118.0m | Reduced -208.9k |
| BVF INC/IL 2.63% of their portfolio | 672.8k $102.8m | Reduced -288.2k |
| STATE STREET CORP 0.00% of their portfolio | 653.2k $99.8m | Added +194.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 638.9k $97.6m | Added +236.3k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 513.8k $78.5m | Added +36.5k |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.68% of their portfolio | 478.8k $73.2m | Added +104.8k |
| FEDERATED HERMES, INC. 0.10% of their portfolio | 433.0k $66.2m | Unchanged |
| Woodline Partners LP 0.15% of their portfolio | 317.5k $48.5m | Unchanged |
| ORBIMED ADVISORS LLC 0.85% of their portfolio | 292.4k $44.7m | Added +157.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 276.2k $42.2m | Added +70.6k |
| Siren, L.L.C. 0.80% of their portfolio | 257.5k $39.3m | Unchanged |
| PRIMECAP MANAGEMENT CO/CA/ 0.02% of their portfolio | 256.2k $39.1m | Added +61.2k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 253.2k $31.6m | Reduced -9.7k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.47% of their portfolio | 231.5k $35.4m | Reduced -1.8k |
| EMERALD ADVISERS, LLC 0.83% of their portfolio | 229.5k $35.1m | Added +68.0k |
| FMR LLC 0.00% of their portfolio | 214.8k $32.8m | Reduced -967 |
| MPM BIOIMPACT LLC 1.90% of their portfolio | 204.0k $31.2m | Reduced -2.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 201.5k $30.8m | Added +7.3k |
| MORGAN STANLEY 0.00% of their portfolio | 181.4k $27.7m | Added +53.4k |
| First Turn Management, LLC 2.56% of their portfolio | 156.4k $23.9m | Added +8.4k |
| Bellevue Group AG 0.50% of their portfolio | 155.0k $23.7m | New |
| EMERALD MUTUAL FUND ADVISERS TRUST 0.70% of their portfolio | 129.8k $19.8m | Added +24.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 129.0k $19.7m | Added +38.1k |
| Aberdeen Group plc 0.03% of their portfolio | 120.2k $18.4m | Added +39.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 97.2k $14.9m | Added +32.8k |
| NEXTBio Capital Management LP 6.32% of their portfolio | 89.9k $13.7m | Added +7.2k |
| Clio Asset Management LLC 10.49% of their portfolio | 86.3k $13.2m | Reduced -4.4k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 83.1k $12.7m | Added +34.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 74.0k $11.3m | Added +9.2k |
| UBS Group AG 0.00% of their portfolio | 72.5k $11.1m | Reduced -32.0k |
| Avidity Partners Management LP 1.71% of their portfolio | 70.0k $10.7m | Reduced -70.0k |
| AWM Investment Company, Inc. 0.92% of their portfolio | 69.4k $10.6m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 67.5k $10.3m | Reduced -2.4k |
| SEVEN GRAND MANAGERS, LLC 0.37% of their portfolio | 60.0k $9.2m | Unchanged |
| Clearbridge Investments, LLC 0.01% of their portfolio | 59.3k $9.1m | Reduced -69 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 54.6k $8.3m | Added +16.6k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 53.3k $8.1m | Added +35.3k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 52.2k $8.0m | Reduced -41.4k |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 51.7k $7.9m | Added +12.4k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 50.0k $7.6m | New |
| Nicholas Investment Partners, LP 0.43% of their portfolio | 49.7k $7.6m | Added +22.1k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 44.5k $6.8m | Reduced -52.2k |
| Lisanti Capital Growth, LLC 1.44% of their portfolio | 43.0k $6.6m | Added +1.5k |
| ROYCE & ASSOCIATES LP 0.05% of their portfolio | 40.5k $6.2m | Added +9.0k |
| WCM INVESTMENT MANAGEMENT, LLC 0.01% of their portfolio | 40.1k $6.2m | Added +176 |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.04% of their portfolio | 39.9k $6.1m | New |
| Jump Financial, LLC 0.05% of their portfolio | 39.4k $6.0m | Added +32.7k |
| Apis Capital Advisors, LLC 0.58% of their portfolio | 39.0k $6.0m | Reduced -50.0k |
| Blue Owl Capital Holdings LP 0.84% of their portfolio | 36.3k $5.5m | Added +5.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 35.6k $5.4m | Added +1.6k |
| FIFTH THIRD BANCORP 0.01% of their portfolio | 35.6k $5.4m | Added +15.6k |
| Invesco Ltd. 0.00% of their portfolio | 33.7k $5.1m | Reduced -14.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 32.6k $5.0m | Added +9.6k |
| FRED ALGER MANAGEMENT, LLC 0.02% of their portfolio | 31.4k $4.8m | Added +10.2k |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC 0.05% of their portfolio | 31.3k $4.8m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 30.6k $4.7m | Added +12.5k |
| Nuveen, LLC 0.00% of their portfolio | 25.2k $3.9m | Added +4.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 25.0k $3.8m | Unchanged |
| NOMURA HOLDINGS INC 0.02% of their portfolio | 24.0k $3.7m | Reduced -45 |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 23.7k $3.6m | Reduced -1.8k |
| Legato Capital Management LLC 0.30% of their portfolio | 23.5k $3.6m | Added +7.5k |
| TD Asset Management Inc 0.00% of their portfolio | 22.7k $3.5m | Unchanged |
| ACT CAPITAL MANAGEMENT, LLC 2.25% of their portfolio | 22.5k $3.4m | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 22.3k $3.4m | Added +8.8k |
| Swiss National Bank 0.00% of their portfolio | 19.4k $3.0m | Unchanged |
| Informed Momentum Co LLC 0.26% of their portfolio | 18.8k $2.9m | Reduced -10.5k |
| F/m Investments LLC 0.14% of their portfolio | 17.4k $2.7m | Added +3.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 17.4k $2.7m | Reduced -1.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 15.5k $2.4m | Reduced -2.4k |
| CITIGROUP INC 0.00% of their portfolio | 15.5k $2.4m | Added +13.0k |
| ALPS ADVISORS INC 0.01% of their portfolio | 14.4k $2.2m | Added +3.2k |
| Capricorn Fund Managers Ltd 0.17% of their portfolio | 14.1k $2.2m | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 13.5k $2.1m | Added +4.4k |
| Trexquant Investment LP 0.01% of their portfolio | 13.5k $2.1m | Reduced -23.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 13.0k $2.0m | Added +7.2k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 12.8k $2.0m | Reduced -3.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 12.3k $1.9m | Added +7.4k |
| OAK RIDGE INVESTMENTS LLC 0.10% of their portfolio | 12.0k $1.8m | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 11.8k $1.8m | Added +4.1k |
| Cresset Asset Management, LLC 0.01% of their portfolio | 11.6k $1.8m | Reduced -231 |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 11.5k $1.8m | Added +128 |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 11.4k $1.7m | Reduced -3.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 11.2k $1.7m | Added +4.3k |
| Calamos Advisors LLC 0.01% of their portfolio | 10.5k $1.6m | Added +675 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 10.4k $1.6m | Reduced -10.7k |
| Mariner, LLC 0.00% of their portfolio | 10.4k $1.6m | Added +5.9k |
| Knights of Columbus Asset Advisors LLC 0.08% of their portfolio | 10.0k $1.5m | Added +2.3k |
| XTX Topco Ltd 0.02% of their portfolio | 8.9k $1.4m | Added +3.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 8.4k $1.3m | Added +2.9k |
| MARTINGALE ASSET MANAGEMENT L P 0.03% of their portfolio | 8.4k $1.3m | New |
| Legal & General Group Plc 0.00% of their portfolio | 8.0k $1.2m | Added +548 |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 7.9k $1.2m | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 6.4k $978.8k | Added +2.1k |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 6.4k $977.9k | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 6.4k $976.8k | Added +463 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 6.4k $976.4k | Added +1.7k |