PALISADE BIO INC PALI
COM · Common Stock · CUSIP 696389402
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCarlsbad, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($941.6k this quarter). Holder counts are more reliable. Shares outstanding: 174.3m as of 2026-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.09.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q2 2024 | 9 |
| Q3 2024 | 10 |
| Q4 2024 | 11 |
| Q1 2025 | 14 |
| Q2 2025 | 12 |
| Q3 2025 | 12 |
| Q4 2025 | 86 |
| Q1 2026 | 96 |
| Q2 2026 | 124 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 4 | 1 |
| Q4 2024 | 6 | 2 |
| Q1 2025 | 9 | 2 |
| Q2 2025 | 5 | 8 |
| Q3 2025 | 9 | 2 |
| Q4 2025 | 77 | 2 |
| Q1 2026 | 58 | 45 |
| Q2 2026 | 82 | 45 |
Biggest buyers
| Soleus Capital Management, L.P. | New | +13.1m |
| BlackRock, Inc. | Added | +8.6m |
| Point72 Asset Management, L.P. | Added | +4.8m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +2.2m |
| Siren, L.L.C. | New | +2.0m |
| STATE STREET CORP | Added | +1.8m |
| Propel Bio Management, LLC | Added | +1.5m |
| Aberdeen Group plc | Added | +1.2m |
| Ally Bridge Group (NY) LLC | New | +1.2m |
| CITADEL ADVISORS LLC | Added | +1.0m |
Biggest sellers
| Commodore Capital LP | Sold out | -7.2m |
| MARSHALL WACE, LLP | Reduced | -2.4m |
| MORGAN STANLEY | Reduced | -2.1m |
| GOLDMAN SACHS GROUP INC | Reduced | -1.8m |
| Balyasny Asset Management L.P. | Reduced | -1.4m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.2m |
| GREAT POINT PARTNERS LLC | Reduced | -1.1m |
| Eversept Partners, LP | Reduced | -804.7k |
| Exome Asset Management LLC | Sold out | -600.0k |
| ADAR1 Capital Management, LLC | Reduced | -538.2k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution new · filed 2025-12-08 | 10.0% |
| ARMISTICE CAPITAL, LLC 13G · institution no change · filed 2025-05-15 | 10.0% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor no change · filed 2026-05-15 | 9.9% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor -2.1 pts · filed 2026-05-15 | 7.9% |
| Soleus Capital Master Fund, L.P. 13G · passive investor +2.1 pts · filed 2026-08-13 | 7.5% |
| Octagon Capital Advisors LP 13G · institution new · filed 2026-02-10 | 6.4% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-29 | 6.0% |
| FRANKLIN RESOURCES INC 13G · institution new · filed 2026-01-29 | 6.0% |
| AMERIPRISE FINANCIAL INC 13G · institution new · filed 2026-05-15 | 5.3% |
Fell to 5% or below in the last year: Commodore Capital LP (0.0%, 2026-08-14), Point72 Asset Management, L.P. (0.2%, 2026-05-15), Squadron Capital Management LLC (3.0%, 2026-02-17), Deep Track Capital, LP (0.0%, 2026-02-13)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 1 | $17.8k | 2 | $10.3k | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 1 | $250.1k | 2 | $410.2k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-09 | Baltera Robert Jr. Director | Bought | $49.0k25.0k shares |
| 2026-07-08 | Baltera Robert Jr. Director | Bought | $39.8k20.0k shares |
| 2026-07-07 | Finley John David CEO, CFO, director | Sold | $303.9k146.8k shares |
| 2026-07-07 | Jones Mitchell Lawrence Chief Medical Officer | Sold | $106.4k51.9k shares |
| 2026-07-07 | Baltera Robert Jr. Director | Bought | $60.9k30.0k shares |
| 2026-07-06 | Baltera Robert Jr. Director | Bought | $41.0k20.0k shares |
| 2026-07-02 | Baltera Robert Jr. Director | Bought | $19.8k10.0k shares |
| 2026-07-01 | Baltera Robert Jr. Director | Bought | $39.6k20.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Soleus Capital Management, L.P. 0.94% of their portfolio | 13.1m $27.3m | New |
| B Group, Inc. 13.54% of their portfolio | 11.4m $23.9m | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 11.1m $23.2m | Reduced -428.9k |
| Jupiter Topco LLC 0.01% of their portfolio | 10.7m $22.4m | First filing |
| BlackRock, Inc. 0.00% of their portfolio | 10.4m $21.8m | Added +8.6m |
| Octagon Capital Advisors LP 1.97% of their portfolio | 10.3m $21.5m | Unchanged |
| PERCEPTIVE ADVISORS LLC 0.27% of their portfolio | 8.4m $17.6m | Reduced -503.1k |
| RA CAPITAL MANAGEMENT, L.P. 0.13% of their portfolio | 7.1m $14.9m | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 5.8m $12.1m | Unchanged |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 5.3m $11.0m | Added +4.8m |
| Boxer Capital Management, LLC 0.76% of their portfolio | 4.8m $10.0m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 4.5m $9.4m | Unchanged |
| Eversept Partners, LP 0.48% of their portfolio | 4.2m $8.7m | Reduced -804.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.8m $7.9m | Added +2.2m |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 3.7m $7.7m | Added +799.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.6m $7.5m | Reduced -1.8m |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 3.1m $6.6m | Unchanged |
| Squadron Capital Management LLC 2.15% of their portfolio | 3.0m $6.3m | Unchanged |
| Propel Bio Management, LLC 2.82% of their portfolio | 2.6m $5.4m | Added +1.5m |
| Vestal Point Capital, LP 0.12% of their portfolio | 2.5m $5.2m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 2.5m $5.2m | Added +1.8m |
| MORGAN STANLEY 0.00% of their portfolio | 2.5m $5.2m | Reduced -2.1m |
| ORBIMED ADVISORS LLC 0.09% of their portfolio | 2.3m $4.9m | Unchanged |
| GREAT POINT PARTNERS LLC 1.13% of their portfolio | 2.3m $4.8m | Reduced -1.1m |
| SPHERA FUNDS MANAGEMENT LTD. 0.68% of their portfolio | 2.3m $4.7m | Added +523.6k |
| HighVista Strategies LLC 0.97% of their portfolio | 2.0m $4.2m | Added +11.6k |
| Siren, L.L.C. 0.08% of their portfolio | 2.0m $4.2m | New |
| Artia Global Partners LP 0.79% of their portfolio | 2.0m $4.2m | Unchanged |
| Aberdeen Group plc 0.01% of their portfolio | 1.9m $4.0m | Added +1.2m |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 1.9m $3.9m | Reduced -1.4m |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.89% of their portfolio | 1.7m $3.6m | Added +499.5k |
| ADAR1 Capital Management, LLC 0.17% of their portfolio | 1.7m $3.6m | Reduced -538.2k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.7m $3.6m | Added +293.5k |
| Ally Bridge Group (NY) LLC 3.31% of their portfolio | 1.2m $2.6m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.2m $2.5m | Added +917.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.1m $2.4m | Reduced -329.6k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.0m $2.1m | Added +1.0m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 994.1k $2.1m | New |
| Nuveen, LLC 0.00% of their portfolio | 969.5k $2.0m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 934.2k $2.0m | Reduced -1.2m |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 885.9k $1.9m | Added +226.6k |
| Ikarian Capital, LLC 0.26% of their portfolio | 750.0k $1.6m | Added +475.0k |
| UBS Group AG 0.00% of their portfolio | 737.3k $1.5m | Reduced -429.6k |
| BIT Capital GmbH 0.04% of their portfolio | 574.0k $1.2m | Added +419.0k |
| Simplify Asset Management Inc. 0.01% of their portfolio | 450.5k $941.6k | Added +100.5k |
| Creek Drive Management Group LLC 0.57% of their portfolio | 440.0k $919.6k | Reduced -100.0k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.02% of their portfolio | 437.1k $913.6k | Added +267.5k |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 0.06% of their portfolio | 436.7k $912.8k | Added +111.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 435.0k $909.1k | Added +359.0k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 398.8k $833.5k | Reduced -2.4m |
| Bank of New York Mellon Corp 0.00% of their portfolio | 348.5k $728.3k | Added +335.6k |
| ACT CAPITAL MANAGEMENT, LLC 0.42% of their portfolio | 307.5k $642.7k | Added +50.0k |
| Seven Fleet Capital Management LP 0.09% of their portfolio | 272.2k $568.9k | Added +59.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 173.9k $363.4k | Reduced -23.2k |
| Virtu Financial LLC 0.01% of their portfolio | 167.2k $349.0k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 160.8k $336.0k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 144.0k $301.0k | New |
| LPL Financial LLC 0.00% of their portfolio | 142.2k $297.1k | Added +32.0k |
| XTX Topco Ltd 0.00% of their portfolio | 130.3k $272.2k | Reduced -74.3k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 126.6k $264.6k | Added +99.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 125.6k $262.4k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 124.7k $260.6k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 121.2k $254.0k | New |
| Pale Fire Capital SE 0.02% of their portfolio | 111.4k $232.8k | Unchanged |
| Verdad Advisers, LP 0.20% of their portfolio | 99.7k $208.3k | New |
| SECTORAL ASSET MANAGEMENT INC 0.13% of their portfolio | 88.0k $183.9k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 87.9k $183.7k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 86.0k $179.7k | Reduced -111.0k |
| EntryPoint Capital, LLC 0.04% of their portfolio | 78.5k $164.1k | Reduced -997 |
| Invesco Ltd. 0.00% of their portfolio | 77.4k $161.8k | New |
| CITIGROUP INC 0.00% of their portfolio | 68.5k $143.2k | Reduced -19.2k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 67.9k $141.9k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 67.7k $141.4k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 64.7k $144.3k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 58.4k $122.0k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 52.3k $109.3k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 52.0k $108.8k | New |
| Quinn Opportunity Partners LLC 0.00% of their portfolio | 50.0k $104.5k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 43.5k $91.0k | New |
| Persistent Asset Partners Ltd 0.03% of their portfolio | 41.5k $86.7k | Reduced -194.9k |
| PCG Wealth Advisors, LLC 0.02% of their portfolio | 41.1k $85.9k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 40.1k $83.9k | New |
| BARCLAYS PLC 0.00% of their portfolio | 36.3k $75.8k | Added +34.0k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 33.1k $69.2k | New |
| WINTON GROUP Ltd 0.00% of their portfolio | 32.2k $67.4k | Added +20.7k |
| Total Clarity Wealth Management, Inc. 0.01% of their portfolio | 31.8k $66.5k | Added +4.8k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 31.2k $65.1k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 30.9k $64.6k | New |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 29.2k $33.2k | New |
| STRS OHIO 0.00% of their portfolio | 28.9k $60.4k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 28.1k $58.8k | New |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 27.4k $57.4k | New |
| GSA CAPITAL PARTNERS LLP 0.00% of their portfolio | 25.9k $54.0k | Reduced -17.8k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 24.6k $51.3k | Added +11.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 22.6k $47.1k | Reduced -166.7k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 22.3k $46.5k | New |
| NFSG Corp 0.01% of their portfolio | 20.2k $42.3k | Added +3.2k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 19.8k $41.3k | Added +3.3k |
| ProShare Advisors LLC 0.00% of their portfolio | 19.3k $40.4k | New |
| Voleon Capital Management LP 0.00% of their portfolio | 18.8k $39.4k | New |