PTC THERAPEUTICS INC PTCT
COM · Common Stock · CUSIP 69366J200 · ISIN US69366J2006
Pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWarren, NJ
- Founded1998
- Websiteptcbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 75.5m as of 2023-10-24, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $22.62. Options: 10 managers hold calls ($8.5m notional), 8 hold puts ($10.7m).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 213 |
| Q4 2022 | 203 |
| Q1 2023 | 203 |
| Q2 2023 | 207 |
| Q3 2023 | 182 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 93 | 118 |
| Q1 2023 | 108 | 98 |
| Q2 2023 | 112 | 95 |
| Q3 2023 | 104 | 105 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $15.3m | $5.6m | 0.37 |
| Q1 2023 | $15.7m | $10.1m | 0.64 |
| Q2 2023 | $18.4m | $4.8m | 0.26 |
| Q3 2023 | $8.5m | $10.7m | 1.27 |
Biggest buyers
| ARMISTICE CAPITAL, LLC | Added | +2.9m |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +2.6m |
| Camber Capital Management LP | Added | +900.0k |
| Man Group plc | New | +523.8k |
| GREAT POINT PARTNERS LLC | New | +500.0k |
| VANGUARD GROUP INC | Added | +393.0k |
| RENAISSANCE TECHNOLOGIES LLC | New | +234.6k |
| AMERIPRISE FINANCIAL INC | Added | +234.6k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | New | +173.2k |
| Rockefeller Capital Management L.P. | Added | +165.7k |
Biggest sellers
| FMR LLC | Reduced | -1.8m |
| FRANKLIN RESOURCES INC | Reduced | -1.3m |
| LOOMIS SAYLES & CO L P | Sold out | -1.1m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -974.5k |
| Bank of New York Mellon Corp | Reduced | -642.8k |
| TimesSquare Capital Management, LLC | Sold out | -572.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -528.2k |
| JANUS HENDERSON GROUP PLC | Reduced | -524.4k |
| VICTORY CAPITAL MANAGEMENT INC | Sold out | -398.7k |
| Sofinnova Investments, Inc. | Sold out | -260.4k |
Biggest calls
| Caption Management, LLC | Reduced | $2.2m100.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.5m68.8k shares |
| JANE STREET GROUP, LLC | Added | $1.3m56.0k shares |
| Parallax Volatility Advisers, L.P. | New | $1.0m45.0k shares |
| SIMPLEX TRADING, LLC | Added | $710.0k31.7k shares |
| MOORE CAPITAL MANAGEMENT, LP | New | $683.5k30.5k shares |
| Jefferies Financial Group Inc. | New | $672.3k30.0k shares |
| GROUP ONE TRADING LLC | Reduced | $186.0k8.3k shares |
| CITADEL ADVISORS LLC | Reduced | $181.5k8.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $9.0m401.8k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | New | $753.0k33.6k shares |
| WOLVERINE ASSET MANAGEMENT LLC | New | $387.7k17.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $318.2k14.2k shares |
| CITADEL ADVISORS LLC | Reduced | $156.9k7.0k shares |
| GROUP ONE TRADING LLC | Reduced | $65.0k2.9k shares |
| SIMPLEX TRADING, LLC | Unchanged | $64.0k2.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +6.8 pts · filed 2025-12-04 | 14.8% |
| JANUS HENDERSON GROUP PLC 13G · institution +2.7 pts · filed 2026-05-15 | 8.7% |
| ARMISTICE CAPITAL, LLC 13G · institution -1.4 pts · filed 2025-05-15 | 6.9% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.9% |
| STATE STREET CORP 13G · institution new · filed 2026-02-09 | 5.2% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
Fell to 5% or below in the last year: TORONTO DOMINION BANK (3.7%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), WELLINGTON MANAGEMENT GROUP LLP (4.8%, 2026-02-10)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 8 | $2.2m | — |
| Q2 2022 | 0 | — | 5 | $210.8k | — |
| Q3 2022 | 0 | — | 2 | $183.2k | — |
| Q4 2022 | 0 | — | 1 | $379.6k | — |
| Q1 2023 | 0 | — | 8 | $3.5m | $2.3m |
| Q2 2023 | 0 | — | 8 | $7.3m | $7.3m |
| Q3 2023 | 0 | — | 1 | $465.0k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-09-06 | Young Alethia Director | Sold | $465.0k11.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| WELLINGTON MANAGEMENT GROUP LLP 0.04% of their portfolio | 9.4m $211.5m | Added +2.6m |
| FMR LLC 0.02% of their portfolio | 8.5m $189.7m | Reduced -1.8m |
| VANGUARD GROUP INC 0.00% of their portfolio | 7.9m $178.1m | Added +393.0k |
| RTW INVESTMENTS, LP 3.42% of their portfolio | 7.2m $162.1m | Unchanged |
| BlackRock Inc. 0.00% of their portfolio | 6.9m $155.4m | Added +68.1k |
| ARMISTICE CAPITAL, LLC 4.10% of their portfolio | 6.2m $137.8m | Added +2.9m |
| Camber Capital Management LP 2.74% of their portfolio | 3.4m $76.2m | Added +900.0k |
| STATE STREET CORP 0.00% of their portfolio | 3.2m $71.0m | Reduced -1.6k |
| JANUS HENDERSON GROUP PLC 0.05% of their portfolio | 3.1m $68.8m | Reduced -524.4k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 2.1m $46.1m | Reduced -1.3m |
| MACQUARIE GROUP LTD 0.05% of their portfolio | 1.7m $38.8m | Reduced -219.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.5m $34.1m | Added +62.3k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.15% of their portfolio | 1.1m $25.2m | Added +104.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.1m $24.7m | Reduced -974.5k |
| Blackstone Inc. 0.11% of their portfolio | 1.1m $24.5m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 882.6k $19.8m | Reduced -40.9k |
| D. E. Shaw & Co., Inc. 0.03% of their portfolio | 840.8k $18.8m | Added +107.8k |
| Pictet Asset Management Holding SA 0.02% of their portfolio | 804.4k $18.0m | First filing |
| COWEN AND COMPANY, LLC 1.26% of their portfolio | 799.5k $17.9m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 691.2k $15.5m | Added +5.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 635.8k $14.2m | Added +234.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 596.8k $13.4m | Added +23.3k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% of their portfolio | 559.3k $12.5m | Added +31.4k |
| NORGES BANK 0.00% of their portfolio | 533.9k $12.0m | Added +3.8k |
| Man Group plc 0.04% of their portfolio | 523.8k $11.7m | New |
| GREAT POINT PARTNERS LLC 2.11% of their portfolio | 500.0k $11.2m | New |
| MORGAN STANLEY 0.00% of their portfolio | 435.7k $9.8m | Added +54.7k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 379.2k $8.5m | Reduced -78.1k |
| Rockefeller Capital Management L.P. 0.03% of their portfolio | 378.1k $8.5m | Added +165.7k |
| Alyeska Investment Group, L.P. 0.06% of their portfolio | 360.0k $8.1m | Added +10.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 339.9k $7.6m | Reduced -86.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 307.6k $6.9m | Reduced -642.8k |
| PANAGORA ASSET MANAGEMENT INC 0.04% of their portfolio | 304.4k $6.8m | Reduced -16.0k |
| Candriam S.C.A. 0.05% of their portfolio | 291.7k $6.5m | Unchanged |
| Jefferies Financial Group Inc. 0.15% of their portfolio | 268.1k $6.0m | Added +240 |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 234.6k $5.3m | New |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 220.4k $4.9m | Added +30.8k |
| SPHERA FUNDS MANAGEMENT LTD. 1.17% of their portfolio | 218.5k $4.9m | Added +118.4k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 209.5k $4.7m | Reduced -1.8k |
| Invesco Ltd. 0.00% of their portfolio | 208.7k $4.7m | Added +44.5k |
| CITIGROUP INC 0.01% of their portfolio | 207.1k $4.6m | Added +116.8k |
| Rafferty Asset Management, LLC 0.03% of their portfolio | 206.3k $4.6m | Added +13.2k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 204.1k $4.6m | Reduced -82.3k |
| TWINBEECH CAPITAL LP 0.08% of their portfolio | 192.5k $4.3m | Added +153.3k |
| SECTORAL ASSET MANAGEMENT INC 0.82% of their portfolio | 187.0k $4.2m | Reduced -44.7k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 179.7k $4.0m | Added +39.2k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio | 173.2k $3.9m | New |
| PINNACLE ASSOCIATES LTD 0.07% of their portfolio | 157.2k $3.5m | Reduced -6.8k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 150.0k $3.4m | Reduced -528.2k |
| Swiss National Bank 0.00% of their portfolio | 146.8k $3.3m | Added +2.1k |
| BARCLAYS PLC 0.00% of their portfolio | 142.7k $3.2m | Added +30.4k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 132.3k $3.0m | Added +89.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 131.1k $2.9m | Reduced -4.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 125.4k $2.8m | Added +51.1k |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 110.4k $2.5m | Added +37.8k |
| California Public Employees Retirement System 0.00% of their portfolio | 108.2k $2.4m | Reduced -35.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 107.0k $2.4m | Added +1.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 106.9k $2.4m | Added +100.0k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 102.3k $2.3m | Added +45.6k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 102.1k $2.3m | Reduced -51.2k |
| Legal & General Group Plc 0.00% of their portfolio | 100.7k $2.3m | Added +2.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 97.5k $2.2m | Reduced -17.3k |
| UBS Group AG 0.00% of their portfolio | 77.9k $1.7m | Reduced -14.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 75.7k $1.7m | Added +2.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 74.6k $1.7m | Reduced -7.4k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 73.8k $1.7m | Added +10.2k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 72.7k $1.6m | Reduced -16.8k |
| Walleye Capital LLC 0.02% of their portfolio | 72.0k $1.6m | Added +65.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 65.8k $1.5m | Reduced -15.8k |
| SEVEN EIGHT CAPITAL, LP 0.17% of their portfolio | 64.7k $1.5m | New |
| Phocas Financial Corp. 0.21% of their portfolio | 64.7k $1.4m | Reduced -16.0k |
| PDT Partners, LLC 0.18% of their portfolio | 64.4k $1.4m | Added +1.5k |
| State of New Jersey Common Pension Fund D 0.00% of their portfolio | 61.6k $1.4m | Added +4.6k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 60.0k $1.3m | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 59.7k $1.3m | Added +2.9k |
| TD Asset Management Inc 0.00% of their portfolio | 59.1k $1.3m | Reduced -7.6k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 53.3k $1.2m | Reduced -10.0k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 52.0k $1.2m | Added +46.2k |
| Engineers Gate Manager LP 0.04% of their portfolio | 47.6k $1.1m | Added +39.9k |
| PUTNAM INVESTMENTS LLC 0.00% of their portfolio | 46.2k $1.0m | Reduced -401 |
| George Kaiser Family Foundation 1.22% of their portfolio | 45.8k $6.5m | Reduced -7.8k |
| SG Americas Securities, LLC 0.01% of their portfolio | 42.9k $962.0k | Added +21.2k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio | 42.6k $954.7k | Reduced -2.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 42.4k $949.5k | Reduced -115 |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 39.4k $883.7k | Added +122 |
| MML INVESTORS SERVICES, LLC 0.00% of their portfolio | 39.2k $879.0k | Added +10.3k |
| Point72 Middle East FZE 0.05% of their portfolio | 38.4k $860.6k | Reduced -5.9k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 37.4k $837.7k | Added +5.1k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 37.2k $833.2k | Unchanged |
| DUALITY ADVISERS, LP 0.10% of their portfolio | 36.0k $806.2k | Added +145 |
| Skandinaviska Enskilda Banken AB (publ) 0.01% of their portfolio | 35.9k $806.0k | Unchanged |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 35.8k $802.0k | New |
| PROFUND ADVISORS LLC 0.04% of their portfolio | 35.4k $792.8k | Reduced -337 |
| AMERICAN INTERNATIONAL GROUP, INC. 0.01% of their portfolio | 35.4k $792.3k | Added +1.3k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 30.5k $684.4k | Reduced -21.3k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 30.4k $680.6k | Reduced -8.7k |
| HARBOR CAPITAL ADVISORS, INC. 0.14% of their portfolio | 29.3k $656.9k | Reduced -1.5k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 29.1k $653.0k | Unchanged |
| Knights of Columbus Asset Advisors LLC 0.06% of their portfolio | 29.1k $652.5k | Added +692 |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 28.3k $635.0k | Added +5.2k |