OS THERAPIES INCORPORATED OSTX
COM NEW · Common Stock · CUSIP 68764Y207
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 46.1m as of 2026-08-12, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.90.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2024 | 8 |
| Q4 2024 | 6 |
| Q1 2025 | 7 |
| Q2 2025 | 14 |
| Q3 2025 | 25 |
| Q4 2025 | 25 |
| Q1 2026 | 29 |
| Q2 2026 | 29 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2024 | 3 | 5 |
| Q1 2025 | 4 | 2 |
| Q2 2025 | 9 | 1 |
| Q3 2025 | 18 | 3 |
| Q4 2025 | 15 | 10 |
| Q1 2026 | 16 | 8 |
| Q2 2026 | 21 | 9 |
Biggest buyers
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +308.2k |
| BlackRock, Inc. | Added | +177.7k |
| MARSHALL WACE, LLP | New | +100.6k |
| HighTower Advisors, LLC | Added | +70.3k |
| VANGUARD FIDUCIARY TRUST CO | Added | +57.5k |
| STATE STREET CORP | Added | +28.9k |
| AXQ CAPITAL, LP | New | +24.6k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +21.7k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Added | +20.0k |
| Quadrature Capital Ltd | New | +15.7k |
Biggest sellers
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -435.2k |
| UBS Group AG | Reduced | -339.9k |
| SANDERS MORRIS HARRIS LLC | Sold out | -32.0k |
| XTX Topco Ltd | Sold out | -31.6k |
| JANE STREET GROUP, LLC | Reduced | -13.3k |
| MERCER GLOBAL ADVISORS INC /ADV | Sold out | -10.2k |
| LPL Financial LLC | Sold out | -10.1k |
| Tower Research Capital LLC (TRC) | Sold out | -4.2k |
| FMR LLC | Sold out | -2 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Ayala Pharmaceuticals, Inc. 13G · passive investor new · filed 2025-04-16 | 10.0% |
| SATTERFIELD THOMAS A JR 13G · passive investor +3.5 pts · filed 2025-08-13 | 9.4% |
| Auerbach Shalom 13D · may seek influence -1.4 pts · filed 2025-08-18 | 8.5% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 777.7k $1.5m | Added +308.2k |
| CM Management, LLC 0.48% of their portfolio | 400.0k $760.0k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 301.8k $573.4k | Added +21.7k |
| HOWARD FINANCIAL SERVICES, LTD. 0.05% of their portfolio | 248.0k $471.2k | Added +2.6k |
| BlackRock, Inc. 0.00% of their portfolio | 242.5k $460.7k | Added +177.7k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 174.1k $330.9k | Added +57.5k |
| STATE STREET CORP 0.00% of their portfolio | 120.1k $228.2k | Added +28.9k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 100.6k $191.2k | New |
| HighTower Advisors, LLC 0.00% of their portfolio | 85.5k $162.5k | Added +70.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 70.8k $134.6k | Added +4.8k |
| Beacon Pointe Advisors, LLC 0.00% of their portfolio | 62.5k $118.8k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 45.0k $85.5k | Added +20.0k |
| INGALLS & SNYDER LLC 0.00% of their portfolio | 36.7k $70.0k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 30.4k $57.8k | Added +4.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 27.9k $53.0k | Added +12.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 27.0k $51.3k | Reduced -13.3k |
| AXQ CAPITAL, LP 0.01% of their portfolio | 24.6k $46.8k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 21.0k $39.8k | Unchanged |
| Stratos Wealth Advisors, LLC 0.00% of their portfolio | 19.3k $36.7k | Added +5.5k |
| Quadrature Capital Ltd 0.00% of their portfolio | 15.7k $29.8k | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 14.5k $27.3k | Added +1.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 13.5k $25.7k | Reduced -435.2k |
| MORGAN STANLEY 0.00% of their portfolio | 13.0k $24.7k | Added +3.5k |
| UBS Group AG 0.00% of their portfolio | 8.8k $16.7k | Reduced -339.9k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 7.5k $14.2k | New |
| Steward Partners Investment Advisory, LLC 0.00% of their portfolio | 5.7k $10.8k | New |
| BARCLAYS PLC 0.00% of their portfolio | 1.5k $2.9k | New |
| ARMSTRONG ADVISORY GROUP, INC 0.00% of their portfolio | 100 $190 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 63 $120 | Added +46 |