ORIC PHARMACEUTICALS INC ORIC
COM · Common Stock · CUSIP 68622P109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($87.3k this quarter). Holder counts are more reliable. Shares outstanding: 103.5m as of 2026-04-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.65. Options: 3 managers hold calls ($1.0m notional), 2 hold puts ($959.1k).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 77 |
| Q4 2022 | 65 |
| Q1 2023 | 72 |
| Q2 2023 | 84 |
| Q3 2023 | 92 |
| Q4 2023 | 93 |
| Q1 2024 | 113 |
| Q2 2024 | 114 |
| Q3 2024 | 123 |
| Q4 2024 | 130 |
| Q1 2025 | 144 |
| Q2 2025 | 143 |
| Q3 2025 | 152 |
| Q4 2025 | 165 |
| Q1 2026 | 182 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 74 | 38 |
| Q3 2024 | 58 | 52 |
| Q4 2024 | 67 | 46 |
| Q1 2025 | 81 | 53 |
| Q2 2025 | 77 | 86 |
| Q3 2025 | 91 | 54 |
| Q4 2025 | 97 | 55 |
| Q1 2026 | 89 | 85 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $10.5m | $102.5k | 0.01 |
| Q3 2025 | $447.2k | $2.2m | 4.88 |
| Q4 2025 | $382.8k | $0 | 0.00 |
| Q1 2026 | $1.0m | $959.1k | 0.92 |
Biggest buyers
| AIHC Capital Management Ltd | New | +2.5m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +2.1m |
| Siren, L.L.C. | Added | +2.0m |
| BRAIDWELL LP | New | +1.1m |
| Woodline Partners LP | Added | +1.0m |
| Defilade Capital Management, L.P. | New | +842.9k |
| Sofinnova Investments, Inc. | New | +679.6k |
| Candriam S.C.A. | New | +574.1k |
| BANK OF AMERICA CORP /DE/ | Added | +535.6k |
| Logos Global Management LP | Added | +500.0k |
Biggest sellers
| Point72 Asset Management, L.P. | Sold out | -2.9m |
| Venrock Adviser, LLC | Reduced | -1.4m |
| ORBIMED ADVISORS LLC | Reduced | -947.8k |
| VIKING GLOBAL INVESTORS LP | Reduced | -748.2k |
| BARCLAYS PLC | Reduced | -706.1k |
| Paradigm Biocapital Advisors LP | Reduced | -700.0k |
| Pfizer Inc | Reduced | -595.9k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -572.7k |
| STATE STREET CORP | Reduced | -556.2k |
| UBS Group AG | Reduced | -540.2k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $903.4k71.3k shares |
| CITADEL ADVISORS LLC | Reduced | $126.7k10.0k shares |
| SIMPLEX TRADING, LLC | Added | $8.9k700 shares |
Biggest puts
| JANE STREET GROUP, LLC | New | $954.1k75.3k shares |
| SIMPLEX TRADING, LLC | New | $5.1k400 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Nextech Crossover I GP S.a r.l. 13G · passive investor filed 2025-08-14 | 8.4% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.8% |
| EcoR1 Capital, LLC 13G · institution new · filed 2025-08-05 | 6.9% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-01-21 | 5.6% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Venrock Healthcare Capital Partners III, L.P. (4.2%, 2026-05-15), PFIZER INC (3.3%, 2026-05-12), COLUMN GROUP II, LP (3.7%, 2025-11-17), ALKEON CAPITAL MANAGEMENT LLC (4.6%, 2025-11-13)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 3 | $350.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $263.0k | 1 | $416.3k | $416.3k |
| Q3 2025 | 0 | — | 2 | $2.0m | $2.0m |
| Q4 2025 | 0 | — | 3 | $1.7m | $1.3m |
| Q1 2026 | 0 | — | 2 | $782.9k | $782.9k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-02-24 | Piscitelli Dominic Chief Financial Officer | Sold plan | $702.5k52.0k shares |
| 2026-01-16 | Heyman Richard A. Director | Sold plan | $42.0k3.5k shares |
| 2026-01-16 | Heyman Richard A. Director · See footnote | Sold plan | $38.4k3.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| Nextech Invest Ltd. 6.39% of their portfolio | 7.2m $90.8m | Unchanged |
| EcoR1 Capital, LLC 3.64% of their portfolio | 6.7m $85.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 6.0m $75.8m | Added +109.5k |
| VIKING GLOBAL INVESTORS LP 0.21% of their portfolio | 5.8m $73.8m | Reduced -748.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 5.4m $68.3m | Added +2.1m |
| Pfizer Inc 24.14% of their portfolio | 4.8m $57.7m | Reduced -595.9k |
| SR One Capital Management, LP 6.39% of their portfolio | 4.5m $58.5m | Unchanged |
| ALKEON CAPITAL MANAGEMENT LLC 0.26% of their portfolio | 4.5m $57.1m | Unchanged |
| Venrock Adviser, LLC 2.04% of their portfolio | 4.3m $54.7m | Reduced -1.4m |
| NEA Management Company, LLC 2.97% of their portfolio | 4.1m $52.2m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 3.7m $46.9m | Reduced -556.2k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.7m $46.7m | First filing |
| Column Group LLC 44.55% of their portfolio | 3.5m $44.9m | Unchanged |
| Siren, L.L.C. 1.05% of their portfolio | 3.0m $38.0m | Added +2.0m |
| ORBIMED ADVISORS LLC 0.74% of their portfolio | 2.7m $34.1m | Reduced -947.8k |
| AIHC Capital Management Ltd 26.04% of their portfolio | 2.5m $31.2m | New |
| FMR LLC 0.00% of their portfolio | 2.4m $30.8m | Reduced -44.8k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 2.4m $30.7m | Reduced -12.0k |
| First Turn Management, LLC 2.86% of their portfolio | 2.0m $25.6m | Added +7.0k |
| Vivo Capital, LLC 1.95% of their portfolio | 1.8m $23.4m | Reduced -269.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $23.3m | Added +88.1k |
| MPM BIOIMPACT LLC 1.77% of their portfolio | 1.8m $22.9m | Added +5.2k |
| Paradigm Biocapital Advisors LP 0.44% of their portfolio | 1.7m $21.6m | Reduced -700.0k |
| MORGAN STANLEY 0.00% of their portfolio | 1.7m $21.3m | Added +488.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.5m $18.7m | Reduced -463.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.5m $18.6m | Added +244.1k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.5m $18.4m | Added +240.3k |
| Integral Health Asset Management, LLC 0.94% of their portfolio | 1.4m $17.7m | Added +200.0k |
| Woodline Partners LP 0.06% of their portfolio | 1.2m $15.8m | Added +1.0m |
| ROYCE & ASSOCIATES LP 0.15% of their portfolio | 1.2m $15.3m | Reduced -300.1k |
| BRAIDWELL LP 0.48% of their portfolio | 1.1m $14.3m | New |
| SILVERARC CAPITAL MANAGEMENT, LLC 1.64% of their portfolio | 1.1m $13.9m | Reduced -16.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.0m $13.2m | Added +535.6k |
| Euclidean Capital LLC 3.20% of their portfolio | 989.4k $12.5m | Unchanged |
| ArrowMark Colorado Holdings LLC 0.32% of their portfolio | 960.5k $12.2m | Reduced -103.3k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.20% of their portfolio | 953.5k $12.1m | Added +1.1k |
| Logos Global Management LP 0.62% of their portfolio | 950.0k $12.0m | Added +500.0k |
| Qube Research & Technologies Ltd 0.02% of their portfolio | 859.5k $10.9m | Reduced -345.9k |
| Defilade Capital Management, L.P. 1.50% of their portfolio | 842.9k $10.7m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 710.9k $9.0m | Reduced -174.6k |
| Sofinnova Investments, Inc. 0.43% of their portfolio | 679.6k $8.6m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 605.0k $7.7m | Reduced -16.0k |
| Candriam S.C.A. 0.04% of their portfolio | 574.1k $7.3m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 570.7k $7.2m | First filing |
| LORD, ABBETT & CO. LLC 0.02% of their portfolio | 542.6k $6.9m | Reduced -21.7k |
| Polar Capital Holdings Plc 0.03% of their portfolio | 539.4k $6.8m | Added +37.0k |
| SPHERA FUNDS MANAGEMENT LTD. 1.17% of their portfolio | 537.6k $6.8m | Reduced -466.8k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 523.8k $6.6m | Reduced -426.4k |
| NEXTBio Capital Management LP 3.08% of their portfolio | 523.6k $6.6m | Reduced -92.1k |
| Connor, Clark & Lunn Investment Management Ltd. 0.02% of their portfolio | 522.1k $6.6m | Added +171.2k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 507.3k $6.4m | First filing |
| Redmile Group, LLC 0.35% of their portfolio | 415.7k $5.3m | Reduced -32.4k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 405.3k $5.1m | Added +72.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 344.3k $4.4m | Reduced -204.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 323.6k $3.9m | Reduced -91.2k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 263.1k $3.3m | Added +56.0k |
| TD Asset Management Inc 0.00% of their portfolio | 258.6k $3.3m | Added +88.8k |
| Atom Investors LP 0.21% of their portfolio | 226.8k $2.9m | Reduced -63.2k |
| UBS Group AG 0.00% of their portfolio | 194.7k $2.5m | Reduced -540.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 190.5k $2.4m | Added +2.5k |
| ExodusPoint Capital Management, LP 0.02% of their portfolio | 186.1k $2.4m | Added +77.3k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 186.1k $2.4m | Reduced -5.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 182.1k $2.3m | Added +53.5k |
| Boxer Capital Management, LLC 0.29% of their portfolio | 176.5k $2.2m | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 170.1k $2.2m | Reduced -4.2k |
| Hennion & Walsh Asset Management, Inc. 0.07% of their portfolio | 160.1k $2.0m | Reduced -10.0k |
| Nuveen, LLC 0.00% of their portfolio | 153.0k $1.9m | Added +8.6k |
| Blue Owl Capital Holdings LP 0.52% of their portfolio | 150.0k $1.9m | Reduced -365.0k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 146.8k $1.9m | Added +11.9k |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 137.5k $1.7m | New |
| ALGERT GLOBAL LLC 0.03% of their portfolio | 136.3k $1.7m | Added +95.8k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 115.5k $1.5m | Reduced -61.7k |
| SUPERSTRING CAPITAL MANAGEMENT LP 1.04% of their portfolio | 115.2k $1.5m | Reduced -140.1k |
| Y-Intercept (Hong Kong) Ltd 0.03% of their portfolio | 112.0k $1.4m | Reduced -229.4k |
| Invesco Ltd. 0.00% of their portfolio | 109.0k $1.4m | Reduced -788 |
| Ishara Investments LP 1.31% of their portfolio | 102.5k $1.3m | Reduced -57.5k |
| DAFNA Capital Management LLC 0.22% of their portfolio | 98.7k $945.5k | Reduced -42.3k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 96.1k $1.2m | New |
| Abu Dhabi Investment Council Co P.J.S.C 0.12% of their portfolio | 89.4k $1.1m | First filing |
| Swiss National Bank 0.00% of their portfolio | 86.2k $1.1m | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 79.1k $1.0m | Added +1.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 63.8k $522.0k | Unchanged |
| BOOTHBAY FUND MANAGEMENT, LLC 0.02% of their portfolio | 62.0k $785.0k | Reduced -156.7k |
| MOORE CAPITAL MANAGEMENT, LP 0.03% of their portfolio | 59.6k $754.7k | New |
| Tidal Investments LLC 0.00% of their portfolio | 57.6k $729.8k | New |
| Tema ETFs LLC 0.05% of their portfolio | 57.2k $725.1k | Added +29.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 54.2k $687.2k | Added +3.5k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 53.0k $672.0k | Reduced -191.0k |
| PROFUND ADVISORS LLC 0.02% of their portfolio | 51.5k $652.7k | Reduced -13.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 51.3k $650.4k | Added +6.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 48.4k $612.8k | Added +14.4k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.04% of their portfolio | 46.1k $583.7k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 44.4k $562.4k | Added +28.4k |
| XTX Topco Ltd 0.01% of their portfolio | 43.3k $548.5k | Reduced -67.3k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 43.1k $546.5k | New |
| SummitTX Capital, L.P. 0.02% of their portfolio | 42.4k $537.8k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 39.9k $505.0k | First filing |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 39.2k $492.6k | Reduced -1.9k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 39.1k $495.5k | Reduced -43.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 38.3k $485.2k | Reduced -86.0k |