ORIC PHARMACEUTICALS INC ORIC
COM · Common Stock · CUSIP 68622P109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($14.6k this quarter). Holder counts are more reliable. Shares outstanding: 71.1m as of 2025-04-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.58. Options: 4 managers hold calls ($74.0k notional), 4 hold puts ($25.1k).
Trends to Q1 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 77 |
| Q4 2022 | 65 |
| Q1 2023 | 72 |
| Q2 2023 | 84 |
| Q3 2023 | 92 |
| Q4 2023 | 93 |
| Q1 2024 | 113 |
| Q2 2024 | 114 |
| Q3 2024 | 123 |
| Q4 2024 | 130 |
| Q1 2025 | 144 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 56 | 39 |
| Q3 2023 | 43 | 37 |
| Q4 2023 | 54 | 39 |
| Q1 2024 | 66 | 43 |
| Q2 2024 | 74 | 38 |
| Q3 2024 | 58 | 52 |
| Q4 2024 | 67 | 46 |
| Q1 2025 | 81 | 53 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2024 | $51.4k | $0 | 0.00 |
| Q3 2024 | $155.2k | $8.2k | 0.05 |
| Q4 2024 | $3.3m | $51.6k | 0.02 |
| Q1 2025 | $74.0k | $25.1k | 0.34 |
Biggest buyers
| VIKING GLOBAL INVESTORS LP | Added | +2.1m |
| MPM BIOIMPACT LLC | New | +1.4m |
| SILVERARC CAPITAL MANAGEMENT, LLC | Added | +881.9k |
| Vivo Capital, LLC | Added | +802.6k |
| ORBIMED ADVISORS LLC | New | +700.0k |
| NEA Management Company, LLC | Added | +629.5k |
| First Turn Management, LLC | Added | +576.4k |
| CITADEL ADVISORS LLC | Added | +475.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +473.6k |
| Balyasny Asset Management L.P. | Added | +452.0k |
Biggest sellers
| Frazier Life Sciences Management, L.P. | Reduced | -2.5m |
| Avidity Partners Management LP | Sold out | -1.3m |
| Venrock Adviser, LLC | Reduced | -1.2m |
| SUPERSTRING CAPITAL MANAGEMENT LP | Reduced | -761.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -500.0k |
| Altium Capital Management LLC | Sold out | -355.0k |
| Schonfeld Strategic Advisors LLC | Reduced | -297.4k |
| DIADEMA PARTNERS LP | Sold out | -214.3k |
| MORGAN STANLEY | Reduced | -178.7k |
| Monaco Asset Management SAM | Sold out | -135.6k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $63.1k11.3k shares |
| SIMPLEX TRADING, LLC | Added | $7.0k1.3k shares |
| GROUP ONE TRADING LLC | New | $3.9k700 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $15.1k2.7k shares |
| GROUP ONE TRADING LLC | New | $5.0k900 shares |
| SIMPLEX TRADING, LLC | New | $5.0k1.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Nextech Crossover I GP S.a r.l. 13G · passive investor filed 2025-08-14 | 8.4% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.8% |
| EcoR1 Capital, LLC 13G · institution new · filed 2025-08-05 | 6.9% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-01-21 | 5.6% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Venrock Healthcare Capital Partners III, L.P. (4.2%, 2026-05-15), PFIZER INC (3.3%, 2026-05-12), COLUMN GROUP II, LP (3.7%, 2025-11-17), ALKEON CAPITAL MANAGEMENT LLC (4.6%, 2025-11-13)
Insider purchases and sales in Q1 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2023 | 0 | — | 1 | $160.6k | — |
| Q3 2023 | 0 | — | 1 | $160.2k | — |
| Q4 2023 | 0 | — | 3 | $215.4k | — |
| Q1 2024 | 0 | — | 1 | $1.1m | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 3 | $350.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
None reported in Q1 2025.
Holders, Q1 2025
| Manager | Shares | Change |
|---|---|---|
| VIKING GLOBAL INVESTORS LP 0.12% of their portfolio | 6.6m $36.7m | Added +2.1m |
| BlackRock, Inc. 0.00% of their portfolio | 5.4m $30.3m | Added +322.1k |
| Pfizer Inc 5.99% of their portfolio | 5.4m $30.0m | Unchanged |
| Nextech Invest Ltd. 6.85% of their portfolio | 5.3m $29.5m | First filing |
| ALKEON CAPITAL MANAGEMENT LLC 0.13% of their portfolio | 4.0m $22.3m | Added +100.0k |
| Column Group LLC 44.67% of their portfolio | 3.5m $19.8m | Unchanged |
| EcoR1 Capital, LLC 1.13% of their portfolio | 3.4m $19.1m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.2m $17.9m | Added +12.1k |
| Venrock Adviser, LLC 1.51% of their portfolio | 3.2m $17.8m | Reduced -1.2m |
| FMR LLC 0.00% of their portfolio | 2.5m $13.8m | Added +12.6k |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $12.3m | Added +350.3k |
| NEA Management Company, LLC 0.94% of their portfolio | 2.2m $12.3m | Added +629.5k |
| Vivo Capital, LLC 1.54% of their portfolio | 2.1m $11.6m | Added +802.6k |
| SILVERARC CAPITAL MANAGEMENT, LLC 2.40% of their portfolio | 2.1m $11.5m | Added +881.9k |
| First Turn Management, LLC 2.28% of their portfolio | 2.0m $11.3m | Added +576.4k |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 2.0m $11.2m | Added +452.0k |
| Commodore Capital LP 0.82% of their portfolio | 2.0m $11.2m | Unchanged |
| Boxer Capital Management, LLC 2.91% of their portfolio | 1.7m $9.7m | Unchanged |
| Frazier Life Sciences Management, L.P. 0.36% of their portfolio | 1.4m $7.9m | Reduced -2.5m |
| MPM BIOIMPACT LLC 1.34% of their portfolio | 1.4m $7.8m | New |
| ArrowMark Colorado Holdings LLC 0.12% of their portfolio | 1.3m $7.5m | Reduced -49.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.3m $7.4m | Added +37.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $7.3m | Added +27.3k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.0m $5.7m | Added +72.3k |
| Siren, L.L.C. 0.32% of their portfolio | 1.0m $5.6m | Unchanged |
| Euclidean Capital LLC 2.07% of their portfolio | 989.4k $5.5m | Unchanged |
| SUPERSTRING CAPITAL MANAGEMENT LP 5.45% of their portfolio | 819.2k $4.6m | Reduced -761.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 727.8k $4.1m | Added +10.6k |
| ORBIMED ADVISORS LLC 0.09% of their portfolio | 700.0k $3.9m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 546.7k $3.1m | Reduced -7.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 511.9k $2.9m | Added +475.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 509.2k $2.8m | Added +473.6k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 426.9k $2.4m | Reduced -297.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 408.5k $2.3m | Reduced -9.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 294.8k $1.6m | Added +24.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 259.8k $1.4m | Added +147.3k |
| MONTANOVA CAPITAL, LLC 0.06% of their portfolio | 255.0k $1.4m | New |
| DAFNA Capital Management LLC 0.38% of their portfolio | 242.0k $1.4m | New |
| SPHERA FUNDS MANAGEMENT LTD. 0.32% of their portfolio | 234.8k $1.3m | Reduced -38.4k |
| Atom Investors LP 0.14% of their portfolio | 210.7k $1.2m | Added +134.1k |
| Parkman Healthcare Partners LLC 0.13% of their portfolio | 203.0k $1.1m | New |
| CANTOR FITZGERALD, L. P. 0.04% of their portfolio | 200.0k $1.1m | Added +177.3k |
| FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio | 178.7k $997.3k | Reduced -40.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 178.2k $994.5k | Reduced -8.2k |
| MORGAN STANLEY 0.00% of their portfolio | 168.7k $941.2k | Reduced -178.7k |
| Nuveen, LLC 0.00% of their portfolio | 167.5k $934.7k | First filing |
| Bank of New York Mellon Corp 0.00% of their portfolio | 166.2k $927.1k | Reduced -1.1k |
| Hennion & Walsh Asset Management, Inc. 0.04% of their portfolio | 156.6k $874.1k | Reduced -6.3k |
| Nicholas Investment Partners, LP 0.09% of their portfolio | 154.4k $861.4k | New |
| TD Asset Management Inc 0.00% of their portfolio | 152.7k $852.1k | Added +4.9k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 150.3k $838.5k | Added +52.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 129.7k $723.5k | Reduced -531 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 126.7k $706.9k | Added +95.6k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 112.6k $628.5k | Added +4.8k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 107.4k $599.5k | Added +53.6k |
| CITIGROUP INC 0.00% of their portfolio | 104.1k $580.9k | Added +32.3k |
| BARCLAYS PLC 0.00% of their portfolio | 101.8k $568.0k | Reduced -12.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 88.8k $495.2k | Reduced -4.6k |
| UBS Group AG 0.00% of their portfolio | 79.5k $443.8k | Added +4.6k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 77.4k $432.0k | Added +26.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 77.0k $429.6k | Reduced -62.7k |
| Trexquant Investment LP 0.00% of their portfolio | 76.1k $424.6k | New |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 69.0k $385.2k | Added +48.8k |
| Swiss National Bank 0.00% of their portfolio | 68.4k $381.7k | Added +6.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 54.0k $301.2k | Added +26.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 52.0k $290.0k | Reduced -5.5k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 49.5k $276.4k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 47.7k $266.1k | New |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% of their portfolio | 47.6k $265.8k | Reduced -127.2k |
| AlphaQuest LLC 0.03% of their portfolio | 42.7k $238.1k | Added +14.2k |
| NEOS Investment Management LLC 0.00% of their portfolio | 40.9k $228.4k | Reduced -4.5k |
| Tema ETFs LLC 0.07% of their portfolio | 40.9k $228.4k | Reduced -4.5k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 40.9k $228.0k | Reduced -752 |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 40.8k $227.6k | Added +28.6k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 40.8k $227.5k | Added +12.1k |
| Invesco Ltd. 0.00% of their portfolio | 40.4k $225.5k | Added +16.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 40.2k $226.3k | Added +3.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 39.0k $217.6k | Added +3.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 38.5k $214.8k | Added +22.3k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 36.2k $201.8k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 35.6k $198.9k | Added +1.9k |
| LMR Partners LLP 0.00% of their portfolio | 35.3k $197.0k | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 35.3k $196.9k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 33.8k $188.4k | Added +15.0k |
| Legal & General Group Plc 0.00% of their portfolio | 32.5k $181.0k | Reduced -470 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 31.8k $177.6k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 31.2k $174.1k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 30.2k $168.3k | Reduced -447 |
| Jasper Ridge Partners, L.P. 0.00% of their portfolio | 20.9k $116.5k | Unchanged |
| SECTORAL ASSET MANAGEMENT INC 0.09% of their portfolio | 20.0k $111.6k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 19.9k $111.0k | Reduced -46.4k |
| Legato Capital Management LLC 0.01% of their portfolio | 19.5k $108.9k | New |
| Virtus Investment Advisers, LLC 0.03% of their portfolio | 19.5k $108.7k | New |
| XTX Topco Ltd 0.01% of their portfolio | 19.1k $106.5k | Reduced -6.9k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 18.0k $101.8k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 16.5k $92.2k | Reduced -4.2k |
| PROFUND ADVISORS LLC 0.00% of their portfolio | 16.5k $91.9k | Added +5.7k |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 15.8k $88.0k | New |
| Baird Financial Group, Inc. 0.00% of their portfolio | 15.7k $87.6k | Unchanged |
| Clear Harbor Asset Management, LLC 0.01% of their portfolio | 15.1k $84.4k | Added +1.4k |