ORIC PHARMACEUTICALS INC ORIC
COM · Common Stock · CUSIP 68622P109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($119.3k this quarter). Holder counts are more reliable. Shares outstanding: 71.0m as of 2025-02-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $8.07. Options: 7 managers hold calls ($3.3m notional), 2 hold puts ($51.6k).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 77 |
| Q4 2022 | 65 |
| Q1 2023 | 72 |
| Q2 2023 | 84 |
| Q3 2023 | 92 |
| Q4 2023 | 93 |
| Q1 2024 | 113 |
| Q2 2024 | 114 |
| Q3 2024 | 123 |
| Q4 2024 | 130 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 38 | 28 |
| Q2 2023 | 56 | 39 |
| Q3 2023 | 43 | 37 |
| Q4 2023 | 54 | 39 |
| Q1 2024 | 66 | 43 |
| Q2 2024 | 74 | 38 |
| Q3 2024 | 58 | 52 |
| Q4 2024 | 67 | 46 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $3.3m | $116.9k | 0.04 |
| Q2 2024 | $51.4k | $0 | 0.00 |
| Q3 2024 | $155.2k | $8.2k | 0.05 |
| Q4 2024 | $3.3m | $51.6k | 0.02 |
Biggest buyers
| Schonfeld Strategic Advisors LLC | New | +724.3k |
| SUPERSTRING CAPITAL MANAGEMENT LP | Added | +631.2k |
| VIKING GLOBAL INVESTORS LP | Added | +431.0k |
| Balyasny Asset Management L.P. | Added | +424.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +180.1k |
| SPHERA FUNDS MANAGEMENT LTD. | Added | +144.8k |
| Hudson Bay Capital Management LP | New | +120.0k |
| DIMENSIONAL FUND ADVISORS LP | Added | +103.2k |
| NATIXIS | New | +79.9k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Added | +78.8k |
Biggest sellers
| FMR LLC | Reduced | -1.9m |
| Boxer Capital, LLC | Sold out | -1.7m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -265.9k |
| Frazier Life Sciences Management, L.P. | Reduced | -254.6k |
| Avidity Partners Management LP | Reduced | -181.9k |
| Driehaus Capital Management LLC | Sold out | -119.1k |
| STATE STREET CORP | Reduced | -91.9k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Sold out | -78.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -75.0k |
| GOLDMAN SACHS GROUP INC | Reduced | -52.6k |
Biggest calls
| SUPERSTRING CAPITAL MANAGEMENT LP | New | $1.6m200.0k shares |
| Caption Management, LLC | New | $1.1m135.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $355.9k44.1k shares |
| JANE STREET GROUP, LLC | New | $161.4k20.0k shares |
| CITADEL ADVISORS LLC | Reduced | $38.7k4.8k shares |
| SIMPLEX TRADING, LLC | Reduced | $4.0k500 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $51.6k6.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Nextech Crossover I GP S.a r.l. 13G · passive investor filed 2025-08-14 | 8.4% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.8% |
| EcoR1 Capital, LLC 13G · institution new · filed 2025-08-05 | 6.9% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-01-21 | 5.6% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Venrock Healthcare Capital Partners III, L.P. (4.2%, 2026-05-15), PFIZER INC (3.3%, 2026-05-12), COLUMN GROUP II, LP (3.7%, 2025-11-17)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 1 | $160.6k | — |
| Q3 2023 | 0 | — | 1 | $160.2k | — |
| Q4 2023 | 0 | — | 3 | $215.4k | — |
| Q1 2024 | 0 | — | 1 | $1.1m | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 3 | $350.7k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-16 | Chacko Jacob PRESIDENT AND CEO, director | Sold | $204.2k24.7k shares |
| 2024-12-16 | Piscitelli Dominic Chief Financial Officer | Sold | $73.3k8.9k shares |
| 2024-12-16 | Multani Pratik S Chief Medical Officer | Sold | $73.3k8.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| Pfizer Inc 1.67% of their portfolio | 5.4m $43.4m | First filing |
| Nextech Invest Ltd. 6.92% of their portfolio | 5.3m $42.7m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 5.1m $41.3m | Added +11.2k |
| VIKING GLOBAL INVESTORS LP 0.12% of their portfolio | 4.4m $35.8m | Added +431.0k |
| Venrock Adviser, LLC 2.43% of their portfolio | 4.4m $35.5m | Unchanged |
| ALKEON CAPITAL MANAGEMENT LLC 0.18% of their portfolio | 3.9m $31.5m | Unchanged |
| Frazier Life Sciences Management, L.P. 1.30% of their portfolio | 3.9m $31.4m | Reduced -254.6k |
| Column Group LLC 51.26% of their portfolio | 3.5m $28.6m | Unchanged |
| EcoR1 Capital, LLC 1.10% of their portfolio | 3.4m $27.6m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.2m $25.9m | Added +36.5k |
| FMR LLC 0.00% of their portfolio | 2.5m $19.9m | Reduced -1.9m |
| Commodore Capital LP 1.18% of their portfolio | 2.0m $16.1m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 1.8m $14.9m | Reduced -91.9k |
| Boxer Capital Management, LLC 1.19% of their portfolio | 1.7m $14.0m | First filing |
| SUPERSTRING CAPITAL MANAGEMENT LP 11.20% of their portfolio | 1.6m $12.8m | Added +631.2k |
| NEA Management Company, LLC 0.71% of their portfolio | 1.6m $12.6m | Added +66.1k |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 1.6m $12.6m | Added +424.2k |
| First Turn Management, LLC 2.10% of their portfolio | 1.5m $11.7m | Unchanged |
| ArrowMark Colorado Holdings LLC 0.15% of their portfolio | 1.4m $11.3m | Added +40.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.3m $10.5m | Added +180.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $10.3m | Added +5.2k |
| Vivo Capital, LLC 1.16% of their portfolio | 1.3m $10.3m | Unchanged |
| Avidity Partners Management LP 1.02% of their portfolio | 1.3m $10.2m | Reduced -181.9k |
| SILVERARC CAPITAL MANAGEMENT, LLC 2.13% of their portfolio | 1.2m $9.5m | Added +78.8k |
| Siren, L.L.C. 0.36% of their portfolio | 1.0m $8.1m | Unchanged |
| Euclidean Capital LLC 1.08% of their portfolio | 989.4k $8.0m | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 950.5k $7.7m | Added +63 |
| Schonfeld Strategic Advisors LLC 0.04% of their portfolio | 724.3k $5.8m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 717.2k $5.8m | Added +103.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 554.0k $4.5m | Added +28.1k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 500.0k $4.0m | Reduced -75.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 418.0k $3.4m | Added +7.7k |
| Altium Capital Management LLC 0.89% of their portfolio | 355.0k $2.9m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 347.4k $2.8m | Reduced -24.4k |
| SPHERA FUNDS MANAGEMENT LTD. 0.41% of their portfolio | 273.2k $2.2m | Added +144.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 270.0k $2.2m | Reduced -52.6k |
| FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio | 219.3k $1.8m | Reduced -171 |
| DIADEMA PARTNERS LP 1.95% of their portfolio | 214.3k $1.7m | First filing |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 186.4k $1.5m | Added +12.0k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% of their portfolio | 174.8k $1.4m | Added +31.5k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 167.5k $1.4m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 167.3k $1.4m | Added +129 |
| Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio | 162.9k $1.3m | Added +24.9k |
| TD Asset Management Inc 0.00% of their portfolio | 147.8k $1.2m | Added +8.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 139.7k $1.1m | Reduced -44.4k |
| Monaco Asset Management SAM 0.49% of their portfolio | 135.6k $1.1m | Reduced -15.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 130.2k $1.1m | Reduced -452 |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 120.0k $968.4k | New |
| BARCLAYS PLC 0.00% of their portfolio | 114.7k $925.6k | Added +7.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 112.5k $908.0k | Added +28.6k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 107.9k $870.4k | Added +8.4k |
| M&T Bank Corp 0.00% of their portfolio | 99.2k $801.1k | Added +14.1k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 97.5k $786.8k | Reduced -2.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 93.3k $753.1k | Added +4.1k |
| NATIXIS 0.00% of their portfolio | 79.9k $644.8k | New |
| Atom Investors LP 0.08% of their portfolio | 76.6k $618.5k | New |
| UBS Group AG 0.00% of their portfolio | 74.9k $604.7k | Added +3.4k |
| CITIGROUP INC 0.00% of their portfolio | 71.8k $579.4k | Added +25.8k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 66.5k $536.7k | Added +8.3k |
| SG Americas Securities, LLC 0.00% of their portfolio | 66.4k $536.0k | Reduced -3.3k |
| Swiss National Bank 0.00% of their portfolio | 62.4k $503.6k | Added +3.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 57.4k $463.5k | Added +18.7k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 53.9k $434.7k | Reduced -8.0k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 51.4k $414.7k | Reduced -13.2k |
| NEOS Investment Management LLC 0.01% of their portfolio | 45.5k $367.0k | New |
| Tema ETFs LLC 0.15% of their portfolio | 45.5k $367.0k | First filing |
| MetLife Investment Management, LLC 0.00% of their portfolio | 41.6k $335.8k | Added +5.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 37.1k $299.4k | Added +704 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 36.4k $294.0k | Added +30.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 35.9k $289.4k | Added +8.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 35.6k $287.1k | Added +12.5k |
| Verition Fund Management LLC 0.00% of their portfolio | 34.2k $276.0k | Reduced -8.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 33.7k $272.2k | Reduced -36.8k |
| Legal & General Group Plc 0.00% of their portfolio | 32.9k $265.7k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 31.8k $256.9k | Added +891 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 31.1k $250.7k | Added +5.5k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 30.6k $247.0k | Reduced -2.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 28.7k $231.7k | Added +9.2k |
| AlphaQuest LLC 0.03% of their portfolio | 28.4k $229.5k | Added +27.4k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 27.6k $223.0k | Reduced -265.9k |
| XTX Topco Ltd 0.02% of their portfolio | 26.0k $209.5k | Added +14.2k |
| Invesco Ltd. 0.00% of their portfolio | 24.0k $193.3k | Added +1.9k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 23.4k $189.0k | New |
| CANTOR FITZGERALD, L. P. 0.01% of their portfolio | 22.7k $182.7k | New |
| Jasper Ridge Partners, L.P. 0.01% of their portfolio | 20.9k $168.4k | Unchanged |
| ProShare Advisors LLC 0.00% of their portfolio | 20.7k $166.9k | Added +4.9k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 20.3k $163.6k | First filing |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 18.8k $151.6k | Reduced -1.8k |
| Engineers Gate Manager LP 0.00% of their portfolio | 16.6k $133.6k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 16.2k $131.0k | Unchanged |
| Baird Financial Group, Inc. 0.00% of their portfolio | 15.7k $126.6k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 15.0k $120.8k | Added +1.4k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 14.7k $118.3k | Added +13.4k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 14.6k $117.7k | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 14.2k $114.4k | Added +9.1k |
| Clear Harbor Asset Management, LLC 0.01% of their portfolio | 13.7k $110.9k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 13.5k $109.1k | Added +2.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 12.4k $99.9k | First filing |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 12.2k $98.6k | New |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 11.3k $91.3k | Unchanged |