OLEMA PHARMACEUTICALS INC OLMA
COM · Common Stock · CUSIP 68062P106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($309.0k this quarter). Holder counts are more reliable. Shares outstanding: 68.6m as of 2025-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.26. Options: 3 managers hold calls ($202.4k notional), 4 hold puts ($224.9k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 73 |
| Q4 2022 | 68 |
| Q1 2023 | 67 |
| Q2 2023 | 88 |
| Q3 2023 | 98 |
| Q4 2023 | 114 |
| Q1 2024 | 127 |
| Q2 2024 | 130 |
| Q3 2024 | 132 |
| Q4 2024 | 159 |
| Q1 2025 | 136 |
| Q2 2025 | 125 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 53 | 39 |
| Q4 2023 | 72 | 38 |
| Q1 2024 | 69 | 52 |
| Q2 2024 | 79 | 58 |
| Q3 2024 | 65 | 60 |
| Q4 2024 | 82 | 48 |
| Q1 2025 | 70 | 87 |
| Q2 2025 | 74 | 57 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $2.9m | $286.4k | 0.10 |
| Q4 2024 | $1.7m | $9.2k | 0.01 |
| Q1 2025 | $26.7k | $128.2k | 4.80 |
| Q2 2025 | $202.4k | $224.9k | 1.11 |
Biggest buyers
| JANUS HENDERSON GROUP PLC | New | +3.0m |
| Woodline Partners LP | Added | +2.0m |
| MORGAN STANLEY | Added | +985.7k |
| BlackRock, Inc. | Added | +782.8k |
| AMERIPRISE FINANCIAL INC | Added | +773.1k |
| VANGUARD GROUP INC | Added | +395.4k |
| MILLENNIUM MANAGEMENT LLC | Added | +292.2k |
| UBS Group AG | Added | +261.0k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +243.0k |
| ROYAL BANK OF CANADA | Added | +213.7k |
Biggest sellers
| Point72 Asset Management, L.P. | Sold out | -1.4m |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -1.2m |
| MPM BIOIMPACT LLC | Reduced | -551.7k |
| BNP PARIBAS FINANCIAL MARKETS | Reduced | -361.5k |
| MARSHALL WACE, LLP | Reduced | -307.1k |
| JPMORGAN CHASE & CO | Reduced | -254.5k |
| Nuveen, LLC | Reduced | -216.1k |
| Ikarian Capital, LLC | Sold out | -192.0k |
| CITADEL ADVISORS LLC | Reduced | -164.5k |
| JANE STREET GROUP, LLC | Sold out | -138.6k |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $202.0k47.6k shares |
| GROUP ONE TRADING LLC | New | $426100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $133.8k31.4k shares |
| GROUP ONE TRADING LLC | Added | $91.2k21.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Unchanged | $0200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 | 13.8% |
| Paradigm Biocapital Advisors LP 13G · passive investor filed 2025-02-14 | 10.0% |
BIOTECHNOLOGY VALUE FUND L P
13D · may seek influence
filed 2026-10-16
Stated purposeItem 4 is hereby amended to add the following: Effective October 14, 2026, Dr. Gorjan Hrustanovic resigned from the Board. Dr. Hrustanovic also resigned from the Compensation Committee of the Board and the Science and Technology Committee of the Board. Dr. Hrustanovic's resignation was not the result of any disagreement with the Issuer on any matter relating to the Issuer's operations, policies or practices. Full filing |
9.8% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.2 pts · filed 2026-05-15 | 8.2% |
| Bain Capital Life Sciences Opportunities IV, L.P. 13G · passive investor -1.8 pts · filed 2026-05-15 | 8.2% |
| BlackRock, Inc. 13G · institution filed 2026-07-29 | 7.1% |
| Invus Global Management, LLC 13G · passive investor new · filed 2026-03-20 | 5.1% |
Fell to 5% or below in the last year: Deep Track Capital, LP (0.0%, 2026-02-13)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 2 | $19.8m | 2 | $972.4k | $972.4k |
| Q4 2023 | 1 | $1.9m | 5 | $2.8m | $858.0k |
| Q1 2024 | 0 | — | 1 | $913.3k | $913.3k |
| Q2 2024 | 0 | — | 2 | $18.1m | $670.1k |
| Q3 2024 | 0 | — | 1 | $139.2k | $139.2k |
| Q4 2024 | 1 | $4.7m | 6 | $6.7m | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Bain Capital Life Sciences Investors, LLC 3.65% of their portfolio | 6.8m $29.2m | Unchanged |
| Paradigm Biocapital Advisors LP 1.23% of their portfolio | 6.8m $28.8m | Added +23.0k |
| BVF INC/IL 0.81% of their portfolio | 5.3m $22.6m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 4.6m $19.6m | Added +782.8k |
| Woodline Partners LP 0.08% of their portfolio | 3.5m $14.9m | Added +2.0m |
| Deep Track Capital, LP 0.47% of their portfolio | 3.4m $14.7m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.3m $13.9m | Added +395.4k |
| Logos Global Management LP 1.83% of their portfolio | 3.2m $13.7m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 3.0m $12.9m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 3.0m $12.8m | Unchanged |
| MPM BIOIMPACT LLC 1.76% of their portfolio | 2.4m $10.1m | Reduced -551.7k |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 3.44% of their portfolio | 1.9m $8.2m | Unchanged |
| Pictet Asset Management Holding SA 0.01% of their portfolio | 1.9m $8.0m | Unchanged |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.7m $7.3m | Reduced -164.5k |
| Vivo Capital, LLC 0.66% of their portfolio | 1.5m $6.4m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 1.4m $6.1m | Added +985.7k |
| UBS Group AG 0.00% of their portfolio | 1.4m $6.0m | Added +261.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $5.7m | Added +243.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.3m $5.4m | Added +292.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.2m $5.1m | Reduced -112.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 1.2m $5.0m | Added +773.1k |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $4.5m | Added +186.4k |
| Candriam S.C.A. 0.02% of their portfolio | 850.5k $3.6m | Reduced -63 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 799.5k $3.4m | Reduced -109.0k |
| Pier Capital, LLC 0.50% of their portfolio | 771.1k $3.3m | Reduced -46.9k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 724.6k $3.1m | Reduced -16.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 618.2k $2.6m | Added +85.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 499.4k $2.1m | Added +81.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 430.5k $1.8m | Added +81.5k |
| HighVista Strategies LLC 0.44% of their portfolio | 278.4k $1.2m | Added +66.2k |
| DIADEMA PARTNERS LP 0.67% of their portfolio | 253.7k $1.1m | Added +153.7k |
| Affinity Asset Advisors, LLC 0.16% of their portfolio | 250.0k $1.1m | Reduced -75.0k |
| Hennion & Walsh Asset Management, Inc. 0.04% of their portfolio | 248.5k $1.1m | Added +6.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 235.6k $1.0m | Added +213.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 228.0k $971.4k | Reduced -1.2m |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 194.4k $828.4k | Added +119.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 164.3k $699.9k | Added +32.3k |
| BARCLAYS PLC 0.00% of their portfolio | 155.8k $663.9k | Added +2.7k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 144.4k $615.1k | Added +6.4k |
| Birchview Capital, LP 0.57% of their portfolio | 134.0k $570.8k | New |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 130.3k $555.3k | Added +116.2k |
| Nuveen, LLC 0.00% of their portfolio | 128.2k $546.2k | Reduced -216.1k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 113.5k $483.5k | Reduced -62.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 93.1k $396.6k | Added +21.3k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 92.5k $394.1k | Added +29.6k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 88.5k $376.8k | Reduced -3.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 86.0k $366.5k | Added +28.0k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 82.9k $353.0k | Added +37.2k |
| XTX Topco Ltd 0.01% of their portfolio | 80.4k $342.6k | New |
| Invesco Ltd. 0.00% of their portfolio | 79.9k $340.5k | Added +29.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 76.7k $326.6k | Added +32.0k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 72.5k $308.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 70.3k $299.6k | Added +39.3k |
| LPL Financial LLC 0.00% of their portfolio | 66.6k $283.9k | Added +10.7k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 59.0k $251.0k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 58.8k $250.5k | Reduced -5.8k |
| Persistent Asset Partners Ltd 0.22% of their portfolio | 58.3k $248.5k | Added +35.3k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 54.2k $230.8k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 54.1k $230.5k | Reduced -219 |
| PORTLAND INVESTMENT COUNSEL INC. 0.07% of their portfolio | 50.0k $231.0k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 50.0k $213.0k | New |
| EP Wealth Advisors, LLC 0.00% of their portfolio | 46.9k $199.8k | Reduced -1.3k |
| Squarepoint Ops LLC 0.00% of their portfolio | 43.6k $185.8k | Added +20.7k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 38.6k $164.5k | Added +14.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 38.2k $162.8k | Added +15.0k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 37.6k $174.4k | Added +21.9k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 37.6k $160.3k | Added +19.9k |
| ALPS ADVISORS INC 0.00% of their portfolio | 36.9k $157.2k | Reduced -13.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 32.5k $138.4k | Reduced -254.5k |
| Brooklyn Investment Group 0.02% of their portfolio | 32.4k $138.0k | Added +13.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 29.9k $128.0k | Added +12.3k |
| PDT Partners, LLC 0.01% of their portfolio | 28.3k $120.7k | Reduced -46.0k |
| FMR LLC 0.00% of their portfolio | 28.2k $120.3k | Added +26.4k |
| Virtus Investment Advisers, LLC 0.03% of their portfolio | 23.2k $98.7k | Reduced -1.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 22.4k $95.6k | Added +7.1k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 22.1k $94.3k | New |
| Creative Planning 0.00% of their portfolio | 19.5k $83.2k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 16.6k $70.6k | Reduced -7.0k |
| Sanctuary Advisors, LLC 0.00% of their portfolio | 16.3k $69.4k | Added +5.0k |
| TITLEIST ASSET MANAGEMENT, LLC 0.01% of their portfolio | 15.0k $63.9k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 14.8k $62.9k | Added +2.6k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 14.7k $62.6k | Added +2.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 14.2k $60.5k | Added +6.1k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 13.7k $58.5k | Reduced -1.1k |
| J. Goldman & Co LP 0.00% of their portfolio | 13.5k $57.5k | Unchanged |
| ZACKS INVESTMENT MANAGEMENT 0.00% of their portfolio | 12.9k $55.1k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 12.8k $54.5k | Reduced -307.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 12.8k $54.3k | New |
| FNY Investment Advisers, LLC 0.02% of their portfolio | 10.0k $42.0k | Added +5.0k |
| CONWAY CAPITAL MANAGEMENT, INC. 0.02% of their portfolio | 10.0k $42.6k | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 8.9k $37.8k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 8.0k $34.1k | Added +2.6k |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 6.8k $29.1k | Added +5.9k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 6.6k $28.1k | Reduced -361.5k |
| CWM, LLC 0.00% of their portfolio | 6.2k $26.0k | Added +2.0k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 6.1k $25.9k | Added +2.2k |
| Legal & General Group Plc 0.00% of their portfolio | 5.4k $23.1k | Added +1.4k |
| State of Wyoming 0.00% of their portfolio | 5.1k $21.8k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.7k $15.8k | Added +652 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 3.2k $13.7k | New |