Vault-13

OPUS GENETICS INC IRD

COM · Common Stock · CUSIP 67577R102

37 institutional holders -12 vs Q1 2024
2,656,7972.7m shares reported held*
10.1% of all shares outstanding*
$4.1mreported value*
3 new 7 added 15 reduced 14 sold out net sold ≈ $1.3m (-827.0k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($60.1k this quarter). Holder counts are more reliable. Shares outstanding: 26.2m as of 2024-08-09, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.53. Options: 2 managers hold calls ($3.1k notional), 3 hold puts ($3.1k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0204060Q3 22: 38Q4 22: 36Q1 23: 42Q2 23: 49Q3 23: 50Q4 23: 50Q1 24: 49Q2 24: 3737Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202238
Q4 202236
Q1 202342
Q2 202349
Q3 202350
Q4 202350
Q1 202449
Q2 202437

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 19 bought or addedQ4 22: 13 cut or sold outQ4 22Q1 23: 20 bought or addedQ1 23: 11 cut or sold outQ2 23: 31 bought or addedQ2 23: 19 cut or sold outQ2 23Q3 23: 21 bought or addedQ3 23: 23 cut or sold outQ4 23: 25 bought or addedQ4 23: 20 cut or sold outQ4 23Q1 24: 21 bought or addedQ1 24: 18 cut or sold outQ2 24: 10 bought or addedQ2 24: 29 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20221913
Q1 20232011
Q2 20233119
Q3 20232123
Q4 20232520
Q1 20242118
Q2 20241029

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200k$400k$600kQ3 23 calls: $238.8kQ3 23 puts: $80.1kQ3 23P/C 0.34Q4 23 calls: $435.3kQ4 23 puts: $12.0kQ4 23P/C 0.03Q1 24 calls: $234.5kQ1 24 puts: $12.5kQ1 24P/C 0.05Q2 24 calls: $3.1kQ2 24 puts: $3.1kQ2 24P/C 1.00
Numbers
QuarterCallsPutsP/C
Q3 2023$238.8k$80.1k0.34
Q4 2023$435.3k$12.0k0.03
Q1 2024$234.5k$12.5k0.05
Q2 2024$3.1k$3.1k1.00

Biggest buyers

JANE STREET GROUP, LLC New +42,375+42.4k
GEODE CAPITAL MANAGEMENT, LLC Added +31,456+31.5k
ROYAL BANK OF CANADA Added +21,940+21.9k
BlackRock Inc. Added +10,221+10.2k
NATIONAL BANK OF CANADA /FI/ Added +10,000+10.0k
OSAIC HOLDINGS, INC. Added +5,046+5.0k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +3,987+4.0k
UBS Group AG Added +1,475+1.5k
BANK OF AMERICA CORP /DE/ New +213+213
GROUP ONE TRADING LLC New +76+76

Biggest sellers

MAI Capital Management Sold out -223,970-224.0k
MORGAN STANLEY Reduced -112,237-112.2k
RENAISSANCE TECHNOLOGIES LLC Reduced -93,600-93.6k
RICE HALL JAMES & ASSOCIATES, LLC Reduced -68,396-68.4k
AMERICAN CENTURY COMPANIES INC Sold out -65,911-65.9k
CITADEL ADVISORS LLC Reduced -65,432-65.4k
BRIDGEWAY CAPITAL MANAGEMENT, LLC Reduced -46,200-46.2k
MACKENZIE FINANCIAL CORP Sold out -40,814-40.8k
MILLENNIUM MANAGEMENT LLC Sold out -36,628-36.6k
Richmond Brothers, Inc. Reduced -36,157-36.2k

Biggest calls

CITADEL ADVISORS LLC Reduced $3.1k2.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC Reduced $3.1k2.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
SIMPLEX TRADING, LLC New $0100 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
PERCEPTIVE ADVISORS LLC 13G · passive investor no change · filed 2026-08-14 10.0% no change 9.2m≈ $37.6m 2026-08-14
Adage Capital Management, L.P. 13G · institution new · filed 2026-05-13 8.5% new 6.0m≈ $24.8m 2026-05-13
Caligan Partners LP 13G · institution -1.2 pts · filed 2026-08-14 7.3% -1.2 pts 6.1m≈ $25.0m 2026-08-14
BALYASNY ASSET MANAGEMENT L.P. 13G · institution -0.5 pts · filed 2026-08-14 6.6% -0.5 pts 5.5m≈ $22.5m 2026-08-14
Nantahala Capital Management, LLC 13G · institution -3.5 pts · filed 2026-05-15 6.5% -3.5 pts 4.8m≈ $19.9m 2026-05-15
BlackRock, Inc. 13G · institution new · filed 2026-10-27 6.1% new 5.0m≈ $20.7m 2026-10-27

Fell to 5% or below in the last year: Foundation Fighting Blindness Retinal Degeneration Fund (4.7%, 2026-05-20), BIOS Fund III, LP (4.5%, 2026-05-13)

Insider purchases and sales in Q2 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 0 sellingQ2 23: 0 buyingQ2 23: 0 sellingQ2 23Q3 23: 0 buyingQ3 23: 0 sellingQ4 23: 0 buyingQ4 23: 0 sellingQ4 23Q1 24: 3 buyingQ1 24: 0 sellingQ2 24: 2 buyingQ2 24: 0 sellingQ2 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20220—0——
Q4 20220—0——
Q1 20230—0——
Q2 20230—0——
Q3 20230—0——
Q4 20230—0——
Q1 20243$74.1k0——
Q2 20242$14.9k0——
DateInsiderTradeSharesPrice ValueTheir holding
2024-05-22 Jayagopal Ashwath Chief Scientific & Dev. Ofc. Bought 3,500 $1.77 $6.2k3.5k shares +5%
2024-05-17 Magrath George Chief Executive Officer Bought 5,000 $1.75 $8.8k5.0k shares +1%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 992,200992.2k $1.5m $1.5m 0.00% Unchanged
2 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 265,854265.9k $406.8k $406.8k 0.00% Added +31.5k +31,456
3 RICE HALL JAMES & ASSOCIATES, LLC 0.02% of their portfolio San Diego, CA 223,589223.6k $342.1k $342.1k 0.02% Reduced -68.4k -68,396
4 Richmond Brothers, Inc. 0.58% of their portfolio JACKSON, MI 191,304191.3k $292.7k $292.7k 0.58% Reduced -36.2k -36,157
5 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 163,741163.7k $250.5k $250.5k 0.01% Reduced -46.2k -46,200
6 BlackRock Inc. 0.00% of their portfolio New York, NY 106,935106.9k $163.6k $163.6k 0.00% Added +10.2k +10,221
7 Knoll Capital Management, LLC 0.10% of their portfolio MIAMI, FL 100,000100.0k $153.0k $153.0k 0.10% Unchanged
8 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 70,47370.5k $107.8k $107.8k 0.00% Unchanged
9 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 56,10556.1k $85.8k $85.8k 0.00% Reduced -112.2k -112,237
10 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 46,57746.6k $71.3k $71.3k 0.00% Added +4.0k +3,987
11 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 42,37542.4k $64.8k $64.8k 0.00% New
12 KESTRA PRIVATE WEALTH SERVICES, LLC 0.00% of their portfolio AUSTIN, TX 42,34142.3k $64.8k $64.8k 0.00% Unchanged
13 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 41,70041.7k $63.8k $63.8k 0.00% Reduced -93.6k -93,600
14 Empowered Funds, LLC 0.00% of their portfolio NEWTOWN SQUARE, PA 39,30539.3k $60.1k $60.1k 0.00% Reduced -33.9k -33,905
15 Diametric Capital, LP 0.03% of their portfolio BOSTON, MA 38,03538.0k $58.2k $58.2k 0.03% Reduced -13.4k -13,359
16 BLAIR WILLIAM & CO/IL 0.00% of their portfolio CHICAGO, IL 33,26733.3k $50.9k $50.9k 0.00% Unchanged
17 TRUST CO OF TOLEDO NA /OH/ 0.01% of their portfolio HOLLAND, OH 30,96331.0k $47.4k $47.4k 0.01% Unchanged
18 COMERICA BANK 0.00% of their portfolio DALLAS, TX 30,00030.0k $45.9k $45.9k 0.00% Unchanged
19 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 27,26727.3k $41.7k $41.7k 0.00% Reduced -24.7k -24,658
20 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 21,94521.9k $34.0k $34.0k 0.00% Added +21.9k +21,940
21 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 21,55521.6k $33.0k $33.0k 0.00% Added +5.0k +5,046
22 CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio RALEIGH, NC 18,00018.0k $27.5k $27.5k 0.00% Unchanged
23 UBS Group AG 0.00% of their portfolio ZURICH, V8 15,70315.7k $24.0k $24.0k 0.00% Added +1.5k +1,475
24 Bedel Financial Consulting, Inc. 0.00% of their portfolio INDIANAPOLIS, IN 15,00015.0k $22.9k $22.9k 0.00% Unchanged
25 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 14,09814.1k $21.6k $21.6k 0.00% Reduced -65.4k -65,432
26 PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 13,85213.9k $21.2k $21.2k 0.00% Reduced -6.8k -6,766
27 Stokes Family Office, LLC 0.00% of their portfolio NEW ORLEANS, LA 12,12012.1k $18.5k $18.5k 0.00% Unchanged
28 NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio MONTREAL, A8 12,00012.0k $19.0k $19.0k 0.00% Added +10.0k +10,000
29 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 3,5923.6k $5.5k $5.5k 0.00% Reduced -3.8k -3,784
30 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 2,7892.8k $4.3k $4.3k 0.00% Reduced -177 -177
31 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 1,3351.3k $2.0k $2.0k 0.00% Reduced -799 -799
32 CarsonAllaria Wealth Management, Ltd. 0.00% of their portfolio GLEN CARBON, IL 1,0001.0k $1.5k $1.5k 0.00% Unchanged
33 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 727727 $1.1k $1.1k 0.00% Reduced -455 -455
34 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 213213 $326 $326 0.00% New
35 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 7676 $116 $116 0.00% New
36 HARBOUR INVESTMENTS, INC. 0.00% of their portfolio MADISON, WI 4040 $61 $61 0.00% Unchanged
37 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 2626 $39 $39 0.00% Reduced -3 -3