Vault-13

OPUS GENETICS INC IRD

COM · Common Stock · CUSIP 67577R102

49 institutional holders -1 vs Q4 2023
3,449,9353.4m shares reported held*
13.9% of all shares outstanding*
$6.9mreported value*
8 new 13 added 10 reduced 8 sold out net sold ≈ $470.6k (-234.2k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($147.2k this quarter). Holder counts are more reliable. Shares outstanding: 24.8m as of 2024-03-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.01. Options: 4 managers hold calls ($234.5k notional), 2 hold puts ($12.5k).

Trends to Q1 2024

Institutional holders

Managers reporting a position, each quarter

0204060Q3 22: 38Q4 22: 36Q1 23: 42Q2 23: 49Q3 23: 50Q4 23: 50Q1 24: 4949Q3 22Q1 23Q3 23Q1 24
Numbers
QuarterHolders
Q3 202238
Q4 202236
Q1 202342
Q2 202349
Q3 202350
Q4 202350
Q1 202449

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 19 bought or addedQ4 22: 13 cut or sold outQ4 22Q1 23: 20 bought or addedQ1 23: 11 cut or sold outQ1 23Q2 23: 31 bought or addedQ2 23: 19 cut or sold outQ2 23Q3 23: 21 bought or addedQ3 23: 23 cut or sold outQ3 23Q4 23: 25 bought or addedQ4 23: 20 cut or sold outQ4 23Q1 24: 21 bought or addedQ1 24: 18 cut or sold outQ1 24
Numbers
QuarterBought or addedCut or sold out
Q4 20221913
Q1 20232011
Q2 20233119
Q3 20232123
Q4 20232520
Q1 20242118

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5mQ2 23 calls: $1.4mQ2 23 puts: $35.6kQ2 23P/C 0.03Q3 23 calls: $238.8kQ3 23 puts: $80.1kQ3 23P/C 0.34Q4 23 calls: $435.3kQ4 23 puts: $12.0kQ4 23P/C 0.03Q1 24 calls: $234.5kQ1 24 puts: $12.5kQ1 24P/C 0.05
Numbers
QuarterCallsPutsP/C
Q2 2023$1.4m$35.6k0.03
Q3 2023$238.8k$80.1k0.34
Q4 2023$435.3k$12.0k0.03
Q1 2024$234.5k$12.5k0.05

Biggest buyers

RENAISSANCE TECHNOLOGIES LLC Added +111,075+111.1k
Empowered Funds, LLC New +73,210+73.2k
VANGUARD GROUP INC Added +64,400+64.4k
CITADEL ADVISORS LLC Added +64,255+64.3k
MORGAN STANLEY Added +56,114+56.1k
MACKENZIE FINANCIAL CORP New +40,814+40.8k
BRIDGEWAY CAPITAL MANAGEMENT, LLC Added +36,605+36.6k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +20,385+20.4k
HRT FINANCIAL LP New +19,868+19.9k
Virtu Financial LLC New +17,752+17.8k

Biggest sellers

RICE HALL JAMES & ASSOCIATES, LLC Reduced -279,792-279.8k
MAI Capital Management Reduced -167,926-167.9k
Squarepoint Ops LLC Sold out -61,152-61.2k
Anson Funds Management LP Sold out -49,339-49.3k
MILLENNIUM MANAGEMENT LLC Reduced -49,238-49.2k
VICTORY CAPITAL MANAGEMENT INC Sold out -46,916-46.9k
JANE STREET GROUP, LLC Sold out -34,691-34.7k
LPL Financial LLC Sold out -26,009-26.0k
Richmond Brothers, Inc. Reduced -25,308-25.3k
Diametric Capital, LP Reduced -21,937-21.9k

Biggest calls

GROUP ONE TRADING LLC Reduced $209.2k104.1k shares
SIMPLEX TRADING, LLC Reduced $18.0k9.4k shares
CITADEL ADVISORS LLC Reduced $7.2k3.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC Added $12.5k6.2k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
PERCEPTIVE ADVISORS LLC 13G · passive investor no change · filed 2026-08-14 10.0% no change 9.2m≈ $37.6m 2026-08-14
Adage Capital Management, L.P. 13G · institution new · filed 2026-05-13 8.5% new 6.0m≈ $24.8m 2026-05-13
Caligan Partners LP 13G · institution -1.2 pts · filed 2026-08-14 7.3% -1.2 pts 6.1m≈ $25.0m 2026-08-14
BALYASNY ASSET MANAGEMENT L.P. 13G · institution -0.5 pts · filed 2026-08-14 6.6% -0.5 pts 5.5m≈ $22.5m 2026-08-14
Nantahala Capital Management, LLC 13G · institution -3.5 pts · filed 2026-05-15 6.5% -3.5 pts 4.8m≈ $19.9m 2026-05-15
BlackRock, Inc. 13G · institution new · filed 2026-10-27 6.1% new 5.0m≈ $20.7m 2026-10-27

Fell to 5% or below in the last year: Foundation Fighting Blindness Retinal Degeneration Fund (4.7%, 2026-05-20), BIOS Fund III, LP (4.5%, 2026-05-13)

Insider purchases and sales in Q1 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q2 22: 2 buyingQ2 22: 0 sellingQ3 22: 0 buyingQ3 22: 0 sellingQ3 22Q4 22: 0 buyingQ4 22: 0 sellingQ1 23: 0 buyingQ1 23: 0 sellingQ1 23Q2 23: 0 buyingQ2 23: 0 sellingQ3 23: 0 buyingQ3 23: 0 sellingQ3 23Q4 23: 0 buyingQ4 23: 0 sellingQ1 24: 3 buyingQ1 24: 0 sellingQ1 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20222$61.1k0——
Q3 20220—0——
Q4 20220—0——
Q1 20230—0——
Q2 20230—0——
Q3 20230—0——
Q4 20230—0——
Q1 20243$74.1k0——
DateInsiderTradeSharesPrice ValueTheir holding
2024-03-21 Jhaveri Nirav S. Chief Financial Officer Bought 10,000 $2.10 $21.0k10.0k shares +7%
2024-03-21 SCHACHLE JOSEPH K Chief Operating Officer Bought 2,000 $2.05 $4.1k2.0k shares new
2024-03-18 Magrath George Chief Executive Officer Bought 25,000 $1.96 $49.0k25.0k shares +6%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q1 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 992,200992.2k $2.0m $2.0m 0.00% Added +64.4k +64,400
2 RICE HALL JAMES & ASSOCIATES, LLC 0.03% of their portfolio San Diego, CA 291,985292.0k $586.9k $586.9k 0.03% Reduced -279.8k -279,792
3 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 234,398234.4k $471.2k $471.2k 0.00% Added +15.3k +15,285
4 Richmond Brothers, Inc. 0.85% of their portfolio JACKSON, MI 227,461227.5k $457.2k $457.2k 0.85% Reduced -25.3k -25,308
5 MAI Capital Management 0.00% of their portfolio INDEPENDENCE, OH 223,970224.0k $450.2k $450.2k 0.00% Reduced -167.9k -167,926
6 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 209,941209.9k $422.0k $422.0k 0.01% Added +36.6k +36,605
7 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 168,342168.3k $338.4k $338.4k 0.00% Added +56.1k +56,114
8 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 135,300135.3k $272.0k $272.0k 0.00% Added +111.1k +111,075
9 Knoll Capital Management, LLC 0.13% of their portfolio MIAMI, FL 100,000100.0k $201.0k $201.0k 0.13% Unchanged
10 BlackRock Inc. 0.00% of their portfolio New York, NY 96,71496.7k $194.4k $194.4k 0.00% Added +2.4k +2,393
11 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 79,53079.5k $159.9k $159.9k 0.00% Added +64.3k +64,255
12 Empowered Funds, LLC 0.00% of their portfolio NEWTOWN SQUARE, PA 73,21073.2k $147.2k $147.2k 0.00% New
13 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 70,47370.5k $141.7k $141.7k 0.00% Unchanged
14 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 65,91165.9k $132.5k $132.5k 0.00% Added +5.7k +5,654
15 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 51,92551.9k $104.4k $104.4k 0.00% Unchanged
16 Diametric Capital, LP 0.06% of their portfolio BOSTON, MA 51,39451.4k $103.3k $103.3k 0.06% Reduced -21.9k -21,937
17 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 42,59042.6k $85.6k $85.6k 0.00% Added +20.4k +20,385
18 KESTRA PRIVATE WEALTH SERVICES, LLC 0.00% of their portfolio AUSTIN, TX 42,34142.3k $85.1k $85.1k 0.00% Unchanged
19 MACKENZIE FINANCIAL CORP 0.00% of their portfolio TORONTO ONTARIO, A6 40,81440.8k $82.0k $82.0k 0.00% New
20 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 36,62836.6k $73.6k $73.6k 0.00% Reduced -49.2k -49,238
21 BLAIR WILLIAM & CO/IL 0.00% of their portfolio CHICAGO, IL 33,26733.3k $66.9k $66.9k 0.00% Unchanged
22 TRUST CO OF TOLEDO NA /OH/ 0.01% of their portfolio HOLLAND, OH 30,96331.0k $62.2k $62.2k 0.01% Unchanged
23 COMERICA BANK 0.00% of their portfolio DALLAS, TX 30,00030.0k $60.3k $60.3k 0.00% Unchanged
24 PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 20,61820.6k $41.4k $41.4k 0.00% Reduced -6.1k -6,059
25 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 19,86819.9k $39.0k $39.0k 0.00% New
26 CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio RALEIGH, NC 18,00018.0k $36.2k $36.2k 0.00% Unchanged
27 Virtu Financial LLC 0.00% of their portfolio New York, NY 17,75217.8k $36.0k $36.0k 0.00% New
28 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 17,40017.4k $35.0k $35.0k 0.00% Added +4.0k +4,000
29 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 16,50916.5k $33.2k $33.2k 0.00% Reduced -800 -800
30 Bedel Financial Consulting, Inc. 0.00% of their portfolio INDIANAPOLIS, IN 15,00015.0k $30.1k $30.1k 0.00% Unchanged
31 UBS Group AG 0.00% of their portfolio ZURICH, V8 14,22814.2k $28.6k $28.6k 0.00% Added +8.8k +8,830
32 Stokes Family Office, LLC 0.00% of their portfolio NEW ORLEANS, LA 12,12012.1k $24.4k $24.4k 0.00% Unchanged
33 LINCOLN NATIONAL CORP 0.00% of their portfolio RADNOR, PA 11,90011.9k $23.9k $23.9k 0.00% Added +200 +200
34 Summit Trail Advisors, LLC 0.00% of their portfolio NEW YORK, NY 10,54510.5k $21.2k $21.2k 0.00% New
35 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 7,3767.4k $14.8k $14.8k 0.00% New
36 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 2,9663.0k $6.0k $6.0k 0.00% Added +15 +15
37 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 2,1342.1k $4.0k $4.0k 0.00% Reduced -7.9k -7,895
38 NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio MONTREAL, A8 2,0002.0k $3.4k $3.4k 0.00% Unchanged
39 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 1,1821.2k $2.4k $2.4k 0.00% Unchanged
40 TOTH FINANCIAL ADVISORY CORP 0.00% of their portfolio LEESBURG, VA 1,0011.0k $2.0k $2.0k 0.00% Unchanged
41 OPTIMUM INVESTMENT ADVISORS 0.00% of their portfolio Chicago, IL 1,0001.0k $2.0k $2.0k 0.00% Unchanged
42 CarsonAllaria Wealth Management, Ltd. 0.00% of their portfolio GLEN CARBON, IL 1,0001.0k $2.0k $2.0k 0.00% Unchanged
43 LANARK FINANCIAL, INC. 0.00% of their portfolio BIRMINGHAM, AL 600600 $1.0k $1.0k 0.00% Unchanged
44 Towne Trust Company, N.A 0.00% of their portfolio NEWPORT NEWS, VA 500500 $1.0k $1.0k 0.00% New
45 HARBOUR INVESTMENTS, INC. 0.00% of their portfolio MADISON, WI 4040 $80 $80 0.00% New
46 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 2929 $58 $58 0.00% Unchanged
47 ICA Group Wealth Management, LLC 0.00% of their portfolio DENVER, CO 1010 $20 $20 0.00% Reduced -20 -20
48 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 55 $0 $0 0.00% Reduced -15.6k -15,631
49 FSA Wealth Management LLC 0.00% of their portfolio Needham, MA 55 $10 $10 0.00% Unchanged