NURIX THERAPEUTICS INC NRIX
COM · Common Stock · CUSIP 67080M103
Company in San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBrisbane, CA
- Founded2012
- Websitenurixtx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($19.5m this quarter). Holder counts are more reliable. Shares outstanding: 103.4m as of 2026-04-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $15.50. Options: 4 managers hold calls ($4.0m notional), 2 hold puts ($237.2k).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 119 |
| Q4 2022 | 120 |
| Q1 2023 | 125 |
| Q2 2023 | 128 |
| Q3 2023 | 131 |
| Q4 2023 | 131 |
| Q1 2024 | 141 |
| Q2 2024 | 176 |
| Q3 2024 | 174 |
| Q4 2024 | 177 |
| Q1 2025 | 172 |
| Q2 2025 | 166 |
| Q3 2025 | 174 |
| Q4 2025 | 183 |
| Q1 2026 | 197 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 111 | 62 |
| Q3 2024 | 92 | 87 |
| Q4 2024 | 92 | 78 |
| Q1 2025 | 92 | 82 |
| Q2 2025 | 92 | 74 |
| Q3 2025 | 84 | 84 |
| Q4 2025 | 123 | 56 |
| Q1 2026 | 103 | 70 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $1.7m | $172.7k | 0.10 |
| Q3 2025 | $1.1m | $104.4k | 0.09 |
| Q4 2025 | $4.7m | $1.6m | 0.34 |
| Q1 2026 | $4.0m | $237.2k | 0.06 |
Biggest buyers
| Vestal Point Capital, LP | Added | +1.8m |
| STATE STREET CORP | Added | +1.6m |
| FMR LLC | Added | +1.3m |
| Capital World Investors | New | +893.3k |
| STEMPOINT CAPITAL LP | New | +630.5k |
| Longaeva Partners L.P. | Added | +562.5k |
| UBS Group AG | Added | +552.9k |
| Qube Research & Technologies Ltd | Added | +459.2k |
| Integral Health Asset Management, LLC | Added | +400.0k |
| Fisher Asset Management, LLC | New | +384.8k |
Biggest sellers
| Point72 Asset Management, L.P. | Reduced | -2.8m |
| GENERAL ATLANTIC, L.P. | Reduced | -795.3k |
| Kynam Capital Management, LP | Reduced | -775.6k |
| Pictet Asset Management Holding SA | Reduced | -741.5k |
| Deep Track Capital, LP | Reduced | -691.2k |
| Logos Global Management LP | Sold out | -500.0k |
| BRAIDWELL LP | Reduced | -433.1k |
| Redmile Group, LLC | Reduced | -361.1k |
| T. Rowe Price Investment Management, Inc. | Sold out | -327.5k |
| Soleus Capital Management, L.P. | Reduced | -281.2k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.3m214.0k shares |
| CITADEL ADVISORS LLC | Added | $567.3k36.6k shares |
| SIMPLEX TRADING, LLC | Added | $51.1k3.3k shares |
| GROUP ONE TRADING LLC | Reduced | $15.5k1.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $223.2k14.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $13.9k900 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-23 | 8.2% |
| Vestal Point Capital, LP 13G · institution +1.5 pts · filed 2026-08-14 | 7.8% |
| Deep Track Capital, LP 13G · passive investor +1.3 pts · filed 2026-08-14 | 7.5% |
| BAKER BROS. ADVISORS LP 13G · institution filed 2026-02-17 | 7.2% |
| Rubric Capital Management LP 13G · institution new · filed 2026-08-14 | 7.0% |
| FMR LLC 13G · institution +1.3 pts · filed 2026-05-06 | 5.4% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor new · filed 2026-09-23 | 5.3% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-08-14 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: Redmile Group, LLC (8.1%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Commodore Capital LP (4.9%, 2025-11-14)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 3 | $602.2k | $543.1k |
| Q3 2024 | 0 | — | 3 | $1.5m | $1.3m |
| Q4 2024 | 0 | — | 3 | $886.4k | $643.6k |
| Q1 2025 | 0 | — | 3 | $504.6k | $311.6k |
| Q2 2025 | 0 | — | 3 | $170.4k | $70.2k |
| Q3 2025 | 0 | — | 3 | $209.1k | $59.6k |
| Q4 2025 | 0 | — | 3 | $927.1k | $788.1k |
| Q1 2026 | 0 | — | 3 | $648.0k | $432.7k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-03-02 | Ring Christine Chief Legal Officer | Sold plan | $125.8k8.1k shares |
| 2026-02-09 | Ring Christine Chief Legal Officer | Sold plan | $237.6k14.3k shares |
| 2026-01-30 | Hansen Gwenn Chief Scientific Officer | Sold | $81.2k4.9k shares |
| 2026-01-30 | Ring Christine Chief Legal Officer | Sold | $73.4k4.4k shares |
| 2026-01-30 | van Houte Hans Chief Financial Officer | Sold | $60.8k3.7k shares |
| 2026-01-20 | Ring Christine Chief Legal Officer | Sold plan | $69.3k3.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 8.9m $138.3m | Added +50.4k |
| Redmile Group, LLC 7.94% of their portfolio | 7.7m $119.9m | Reduced -361.1k |
| Vestal Point Capital, LP 2.82% of their portfolio | 6.5m $100.8m | Added +1.8m |
| Deep Track Capital, LP 2.03% of their portfolio | 6.3m $98.4m | Reduced -691.2k |
| FMR LLC 0.00% of their portfolio | 5.5m $85.9m | Added +1.3m |
| STATE STREET CORP 0.00% of their portfolio | 5.1m $79.7m | Added +1.6m |
| MORGAN STANLEY 0.00% of their portfolio | 4.9m $76.4m | Added +50.9k |
| BAKER BROS. ADVISORS LP 0.41% of their portfolio | 4.7m $72.2m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 4.4m $68.6m | First filing |
| GENERAL ATLANTIC, L.P. 2.96% of their portfolio | 4.1m $63.6m | Reduced -795.3k |
| PERCEPTIVE ADVISORS LLC 1.14% of their portfolio | 3.7m $57.5m | Added +155.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 3.3m $51.0m | Added +41.9k |
| Pictet Asset Management Holding SA 0.04% of their portfolio | 2.7m $42.3m | Reduced -741.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.5m $39.1m | Added +135.2k |
| Rubric Capital Management LP 0.47% of their portfolio | 2.5m $38.3m | Unchanged |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 2.3m $35.6m | Reduced -191.8k |
| Commodore Capital LP 2.04% of their portfolio | 2.3m $35.3m | Unchanged |
| BRAIDWELL LP 0.91% of their portfolio | 1.8m $27.1m | Reduced -433.1k |
| Trails Edge Capital Partners, LP 6.36% of their portfolio | 1.7m $27.0m | Unchanged |
| ARK Investment Management LLC 0.21% of their portfolio | 1.7m $26.7m | Added +118.6k |
| Longaeva Partners L.P. 1.11% of their portfolio | 1.5m $23.1m | Added +562.5k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.3m $20.8m | Added +190.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.3m $20.4m | Added +241.1k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.33% of their portfolio | 1.3m $20.1m | Unchanged |
| Kynam Capital Management, LP 1.18% of their portfolio | 1.2m $18.5m | Reduced -775.6k |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 1.2m $18.3m | Reduced -109.4k |
| Amova Asset Management Americas, Inc. 0.26% of their portfolio | 1.2m $18.3m | Reduced -109.4k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.1m $17.1m | First filing |
| UBS Group AG 0.00% of their portfolio | 976.4k $15.1m | Added +552.9k |
| Affinity Asset Advisors, LLC 0.88% of their portfolio | 967.6k $15.0m | Unchanged |
| Soleus Capital Management, L.P. 0.59% of their portfolio | 938.2k $14.5m | Reduced -281.2k |
| Woodline Partners LP 0.05% of their portfolio | 925.4k $14.3m | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 924.0k $14.3m | Reduced -41.9k |
| Capital World Investors 0.00% of their portfolio | 893.3k $13.8m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 854.5k $13.2m | Added +48.8k |
| Nuveen, LLC 0.00% of their portfolio | 812.6k $12.6m | Added +28.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 802.2k $12.4m | Added +65.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 780.7k $12.1m | Added +349.7k |
| Integral Health Asset Management, LLC 0.57% of their portfolio | 700.0k $10.8m | Added +400.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 632.2k $9.8m | First filing |
| STEMPOINT CAPITAL LP 0.95% of their portfolio | 630.5k $9.8m | New |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.04% of their portfolio | 620.8k $9.6m | Reduced -114.4k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.18% of their portfolio | 561.2k $8.7m | Added +300.0k |
| Handelsbanken Fonder AB 0.03% of their portfolio | 547.0k $8.5m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 546.3k $8.5m | Added +366.5k |
| Candriam S.C.A. 0.04% of their portfolio | 534.3k $8.3m | Unchanged |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 485.2k $7.5m | Added +459.2k |
| CITIGROUP INC 0.00% of their portfolio | 477.4k $7.4m | Added +306.3k |
| Elmind Capital, LP 2.02% of their portfolio | 460.0k $7.1m | Unchanged |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 449.1k $7.0m | Reduced -2.8m |
| Fisher Asset Management, LLC 0.00% of their portfolio | 384.8k $6.0m | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 353.7k $5.2m | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 344.2k $5.3m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 321.4k $5.0m | Added +46.2k |
| ArrowMark Colorado Holdings LLC 0.13% of their portfolio | 314.8k $4.9m | Unchanged |
| Rhenman & Partners Asset Management AB 0.60% of their portfolio | 313.5k $4.9m | Reduced -224.0k |
| BESSEMER GROUP INC 0.01% of their portfolio | 306.0k $4.7m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 295.3k $4.6m | Added +7.2k |
| Foresite Capital Management V, LLC 1.52% of their portfolio | 265.0k $4.1m | New |
| WestHill Financial Advisors, Inc. 0.68% of their portfolio | 228.3k $3.5m | Unchanged |
| HighVista Strategies LLC 0.97% of their portfolio | 226.5k $3.5m | New |
| Squarepoint Ops LLC 0.01% of their portfolio | 224.5k $3.5m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 223.4k $3.5m | Added +91.3k |
| Trexquant Investment LP 0.02% of their portfolio | 209.7k $3.3m | Added +132.3k |
| Invesco Ltd. 0.00% of their portfolio | 203.6k $3.2m | Reduced -140.2k |
| TD Asset Management Inc 0.00% of their portfolio | 189.2k $2.9m | Reduced -48.0k |
| Abu Dhabi Investment Council Co P.J.S.C 0.29% of their portfolio | 185.3k $2.9m | First filing |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 179.2k $2.8m | Added +6.8k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 157.3k $2.4m | Reduced -11.5k |
| Swiss National Bank 0.00% of their portfolio | 150.0k $2.3m | Unchanged |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 149.5k $2.3m | Added +59.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 123.4k $1.9m | Added +4.8k |
| Burkehill Global Management, LP 0.09% of their portfolio | 119.0k $1.8m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 118.0k $1.8m | New |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 107.7k $1.7m | Added +21.2k |
| Boxer Capital Management, LLC 0.20% of their portfolio | 100.0k $1.6m | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 99.0k $1.5m | Added +31.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 98.2k $1.9m | Unchanged |
| Jasper Ridge Partners, L.P. 0.03% of their portfolio | 95.7k $1.5m | Unchanged |
| EDMOND DE ROTHSCHILD HOLDING S.A. 0.02% of their portfolio | 90.0k $1.4m | Added +10.0k |
| Jump Financial, LLC 0.02% of their portfolio | 89.5k $1.4m | Added +9.5k |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group 0.50% of their portfolio | 85.0k $1.3m | Unchanged |
| Verdad Advisers, LP 1.46% of their portfolio | 83.4k $1.3m | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 82.1k $1.3m | Added +46.1k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 81.8k $1.3m | Added +18.4k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.10% of their portfolio | 81.8k $1.3m | Added +16.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 81.5k $1.3m | Added +30.9k |
| FLAX POND CAPITAL, LLC 1.00% of their portfolio | 80.2k $1.2m | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 78.1k $1.2m | Added +35.2k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 77.9k $1.2m | Reduced -1.4k |
| Legal & General Group Plc 0.00% of their portfolio | 70.8k $1.1m | Reduced -14.2k |
| PROFUND ADVISORS LLC 0.04% of their portfolio | 67.0k $1.0m | Added +32.4k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 62.5k $968.8k | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 61.8k $958.3k | Reduced -62.9k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 61.8k $957.5k | Added +41.3k |
| Polymer Capital Management (HK) LTD 0.13% of their portfolio | 58.9k $912.9k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 56.1k $870.1k | Reduced -61.7k |
| ADAR1 Capital Management, LLC 0.05% of their portfolio | 56.1k $869.1k | Reduced -16.0k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 55.9k $867.2k | Added +603 |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 55.1k $854.6k | New |