NURIX THERAPEUTICS INC NRIX
COM · Common Stock · CUSIP 67080M103
Company in San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBrisbane, CA
- Founded2012
- Websitenurixtx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($805.7k this quarter). Holder counts are more reliable. Shares outstanding: 48.2m as of 2023-06-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.98. Options: 4 managers hold calls ($2.2m notional), 3 hold puts ($224.8k).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 119 |
| Q4 2022 | 120 |
| Q1 2023 | 125 |
| Q2 2023 | 128 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 61 | 47 |
| Q1 2023 | 62 | 50 |
| Q2 2023 | 61 | 56 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $1.7m | $1.0k | 0.00 |
| Q4 2022 | $1.8m | $5.5k | 0.00 |
| Q1 2023 | $2.2m | $18.6k | 0.01 |
| Q2 2023 | $2.2m | $224.8k | 0.10 |
Biggest buyers
| WASATCH ADVISORS LP | Added | +695.8k |
| MONTANOVA CAPITAL, LLC | New | +280.8k |
| BlackRock Inc. | Added | +228.2k |
| MILLENNIUM MANAGEMENT LLC | Added | +182.8k |
| DIMENSIONAL FUND ADVISORS LP | Added | +144.0k |
| GLOBEFLEX CAPITAL L P | New | +143.2k |
| Candriam S.C.A. | Added | +119.7k |
| Connor, Clark & Lunn Investment Management Ltd. | Added | +117.4k |
| Redmile Group, LLC | Added | +107.9k |
| ALLIANCEBERNSTEIN L.P. | Added | +85.2k |
Biggest sellers
| FMR LLC | Reduced | -483.9k |
| STATE STREET CORP | Reduced | -309.6k |
| GOLDMAN SACHS GROUP INC | Reduced | -218.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -204.9k |
| NOMURA HOLDINGS INC | Reduced | -158.8k |
| PICTET ASSET MANAGEMENT SA | Reduced | -133.9k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -109.0k |
| CITIGROUP INC | Reduced | -66.1k |
| GSA CAPITAL PARTNERS LLP | Reduced | -54.9k |
| Affinity Asset Advisors, LLC | Reduced | -50.0k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $1.2m124.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $932.1k93.3k shares |
| SIMPLEX TRADING, LLC | Added | $34.0k3.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $122.9k12.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $101.9k10.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-23 | 8.2% |
| Vestal Point Capital, LP 13G · institution +1.5 pts · filed 2026-08-14 | 7.8% |
| Deep Track Capital, LP 13G · passive investor +1.3 pts · filed 2026-08-14 | 7.5% |
| BAKER BROS. ADVISORS LP 13G · institution filed 2026-02-17 | 7.2% |
| Rubric Capital Management LP 13G · institution new · filed 2026-08-14 | 7.0% |
| FMR LLC 13G · institution +1.3 pts · filed 2026-05-06 | 5.4% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor new · filed 2026-09-23 | 5.3% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-08-14 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: Redmile Group, LLC (8.1%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Commodore Capital LP (4.9%, 2025-11-14)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 2 | $185.7k | — |
| Q1 2022 | 0 | — | 2 | $85.5k | — |
| Q2 2022 | 0 | — | 4 | $32.7k | — |
| Q3 2022 | 0 | — | 4 | $47.1k | — |
| Q4 2022 | 0 | — | 4 | $38.0k | — |
| Q1 2023 | 0 | — | 4 | $42.5k | — |
| Q2 2023 | 0 | — | 4 | $28.5k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-05-01 | Hansen Gwenn Chief Scientific Officer | Sold | $11.2k1.1k shares |
| 2023-05-01 | van Houte Hans Chief Financial Officer | Sold | $7.1k721 shares |
| 2023-05-01 | Ring Christine General Counsel | Sold | $6.7k682 shares |
| 2023-05-01 | Wolff Stefani EVP and COO | Sold | $3.4k342 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 4.5m $45.1m | Added +228.2k |
| BAKER BROS. ADVISORS LP 0.22% of their portfolio | 3.9m $38.8m | Unchanged |
| WASATCH ADVISORS LP 0.23% of their portfolio | 3.9m $38.7m | Added +695.8k |
| Deep Track Capital, LP 1.40% of their portfolio | 3.0m $29.9m | Unchanged |
| Redmile Group, LLC 1.10% of their portfolio | 2.9m $28.5m | Added +107.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.7m $26.9m | Added +68.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 2.4m $23.8m | Reduced -204.9k |
| ARK Investment Management LLC 0.15% of their portfolio | 2.3m $22.6m | Added +21.2k |
| STATE STREET CORP 0.00% of their portfolio | 1.9m $19.2m | Reduced -309.6k |
| Bain Capital Life Sciences Investors, LLC 1.88% of their portfolio | 1.8m $18.2m | Unchanged |
| Boxer Capital, LLC 0.57% of their portfolio | 1.2m $12.2m | Unchanged |
| Candriam S.C.A. 0.07% of their portfolio | 1.0m $10.2m | Added +119.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 978.1k $9.8m | Added +47.4k |
| PICTET ASSET MANAGEMENT SA 0.01% of their portfolio | 930.9k $9.3m | Reduced -133.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 777.5k $7.8m | Added +144.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 667.4k $6.7m | Reduced -2.6k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 644.4k $6.4m | Added +182.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 588.0k $5.9m | Reduced -43.2k |
| DAFNA Capital Management LLC 1.52% of their portfolio | 556.7k $5.6m | Reduced -10.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 428.6k $4.3m | Added +28.6k |
| FMR LLC 0.00% of their portfolio | 416.6k $4.2m | Reduced -483.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 384.0k $3.8m | Reduced -881 |
| BESSEMER GROUP INC 0.01% of their portfolio | 357.3k $3.6m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 322.6k $3.2m | Reduced -218.1k |
| HARVARD MANAGEMENT CO INC 0.31% of their portfolio | 314.8k $3.1m | Unchanged |
| WestHill Financial Advisors, Inc. 0.80% of their portfolio | 283.3k $2.8m | Unchanged |
| MONTANOVA CAPITAL, LLC 0.15% of their portfolio | 280.8k $2.8m | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 246.7k $2.2m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 209.1k $2.1m | Reduced -43.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 165.5k $1.7m | Added +7.2k |
| GLOBEFLEX CAPITAL L P 0.16% of their portfolio | 143.2k $1.4m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 140.9k $1.4m | Added +70.4k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 130.5k $1.3m | Added +117.4k |
| NOMURA HOLDINGS INC 0.01% of their portfolio | 130.0k $1.3m | Reduced -158.8k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 121.5k $1.2m | Added +85.2k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 114.5k $1.1m | Reduced -25.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 108.8k $1.1m | Added +5.1k |
| Affinity Asset Advisors, LLC 0.39% of their portfolio | 100.0k $999.0k | Reduced -50.0k |
| Jasper Ridge Partners, L.P. 0.05% of their portfolio | 95.7k $956.2k | Unchanged |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 92.4k $923.5k | Added +24.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 90.9k $907.9k | Added +23.3k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 89.1k $889.9k | Reduced -455 |
| Swiss National Bank 0.00% of their portfolio | 87.9k $878.1k | Added +11.6k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 86.0k $859.0k | Reduced -5.5k |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group 0.39% of their portfolio | 85.0k $849.1k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 80.6k $805.7k | Reduced -4.5k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 79.9k $798.3k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 73.1k $729.8k | Added +244 |
| BARCLAYS PLC 0.00% of their portfolio | 69.0k $689.2k | Reduced -3.2k |
| Jefferies Financial Group Inc. 0.01% of their portfolio | 62.0k $619.4k | New |
| ClariVest Asset Management LLC 0.03% of their portfolio | 59.8k $597.0k | Added +10.8k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 58.6k $585.2k | Added +31.2k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 55.9k $558.5k | New |
| Trexquant Investment LP 0.01% of their portfolio | 55.9k $558.0k | Added +21.1k |
| B. Metzler seel. Sohn & Co. AG 0.01% of their portfolio | 54.1k $540.2k | Added +36.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 52.8k $527.7k | Added +17.1k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 51.5k $514.5k | Reduced -7.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 51.1k $510.1k | Added +2.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 48.1k $480.8k | Added +36.8k |
| Invesco Ltd. 0.00% of their portfolio | 47.7k $476.8k | Reduced -702 |
| CITIGROUP INC 0.00% of their portfolio | 47.0k $469.1k | Reduced -66.1k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 46.9k $468.5k | Reduced -109.0k |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 42.6k $425.1k | Added +17.9k |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 42.4k $423.3k | Added +2.2k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 41.7k $417.0k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 40.0k $399.7k | Added +6.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 38.7k $386.7k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 35.6k $355.2k | Reduced -1.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 34.3k $346.6k | Added +8.9k |
| Mariner, LLC 0.00% of their portfolio | 32.7k $326.7k | Reduced -2.5k |
| Legal & General Group Plc 0.00% of their portfolio | 32.5k $325.1k | Added +17.9k |
| AtonRa Partners 0.47% of their portfolio | 30.1k $301.1k | Reduced -2.8k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 30.1k $300.4k | Added +12.0k |
| HRT FINANCIAL LP 0.00% of their portfolio | 28.4k $284.0k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 28.1k $280.3k | Reduced -1.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 28.0k $279.7k | Reduced -1.3k |
| Corton Capital Inc. 0.13% of their portfolio | 27.6k $275.9k | New |
| Blackstone Inc. 0.00% of their portfolio | 27.1k $270.9k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 23.3k $232.6k | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 23.1k $230.4k | Added +10.5k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 22.9k $228.7k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 22.6k $225.3k | Added +158 |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 21.2k $212.3k | Reduced -5.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 20.8k $207.9k | Reduced -490 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 19.2k $192.2k | Added +1.1k |
| CORNERCAP INVESTMENT COUNSEL INC 0.03% of their portfolio | 18.8k $187.4k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 17.6k $176.0k | Reduced -54.9k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 17.4k $174.1k | Reduced -30 |
| Nebula Research & Development LLC 0.12% of their portfolio | 16.0k $160.1k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 15.8k $157.4k | Reduced -12.7k |
| INNOVIS ASSET MANAGEMENT LLC 0.06% of their portfolio | 15.6k $156.3k | Reduced -14.4k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 15.5k $154.5k | Reduced -41.0k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 15.2k $151.8k | Added +3.3k |
| Delphia (USA) Inc. 0.22% of their portfolio | 14.2k $142.2k | New |
| Fiduciary Trust Co 0.00% of their portfolio | 14.1k $140.6k | Unchanged |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 13.5k $135.2k | Added +725 |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 13.0k $129.8k | Reduced -9.1k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 12.9k $129.0k | Reduced -31 |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 12.3k $123.3k | New |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 11.3k $113.2k | Added +1.1k |