Vault-13

NUVALENT INC

COM · CUSIP 670703107

112 institutional holders +22 vs Q1 2023
55,270,85255.3m shares reported held*
$2.3bnreported value*
30 new 37 added 33 reduced 8 sold out net sold ≈ $275.9m (-6.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $42.17. Options: 5 managers hold calls ($214.8k notional), 2 hold puts ($4.2k).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 60Q4 22: 97Q1 23: 90Q2 23: 112112Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 202260
Q4 202297
Q1 202390
Q2 2023112

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 80 bought or addedQ4 22: 17 cut or sold outQ4 22Q1 23: 54 bought or addedQ1 23: 40 cut or sold outQ1 23Q2 23: 67 bought or addedQ2 23: 41 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20228017
Q1 20235440
Q2 20236741

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$5m$10m$15m$20mQ3 22 calls: $0Q3 22 puts: $0Q3 22P/C —Q4 22 calls: $15.1mQ4 22 puts: $29.8kQ4 22P/C 0.00Q1 23 calls: $17.7mQ1 23 puts: $913.1kQ1 23P/C 0.05Q2 23 calls: $214.8kQ2 23 puts: $4.2kQ2 23P/C 0.02
Numbers
QuarterCallsPutsP/C
Q3 2022$0$0—
Q4 2022$15.1m$29.8k0.00
Q1 2023$17.7m$913.1k0.05
Q2 2023$214.8k$4.2k0.02

Biggest buyers

Paradigm Biocapital Advisors LP New +1,120,465+1.1m
Ikarian Capital, LLC New +272,752+272.8k
BlackRock Inc. Added +200,966+201.0k
Invesco Ltd. New +138,014+138.0k
STATE STREET CORP Added +124,786+124.8k
DIMENSIONAL FUND ADVISORS LP New +114,476+114.5k
GREAT LAKES ADVISORS, LLC New +103,712+103.7k
D. E. Shaw & Co., Inc. Added +80,584+80.6k
Commodore Capital LP Added +75,000+75.0k
NORTHERN TRUST CORP Added +68,062+68.1k

Biggest sellers

FMR LLC Reduced -7,762,724-7.8m
JPMORGAN CHASE & CO Reduced -380,323-380.3k
Avoro Capital Advisors LLC Reduced -288,888-288.9k
JANUS HENDERSON GROUP PLC Reduced -181,038-181.0k
SILVERARC CAPITAL MANAGEMENT, LLC Reduced -166,466-166.5k
WELLINGTON MANAGEMENT GROUP LLP Reduced -150,189-150.2k
PERCEPTIVE ADVISORS LLC Reduced -105,227-105.2k
ENVESTNET ASSET MANAGEMENT INC Sold out -83,697-83.7k
MILLENNIUM MANAGEMENT LLC Sold out -57,633-57.6k
Candriam S.C.A. Reduced -43,835-43.8k

Biggest calls

Ikarian Capital, LLC New $185.5k4.4k shares
GROUP ONE TRADING LLC Reduced $12.7k300 shares
CITADEL ADVISORS LLC Reduced $12.7k300 shares
SIMPLEX TRADING, LLC Reduced $4.0k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC New $4.2k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

No one currently above 5% in the filings since 19 Dec 2024.

Fell to 5% or below in the last year: Flynn James E (0.0%, 2026-07-17), FMR LLC (1.9%, 2026-07-08), VANGUARD GROUP INC (0.0%, 2026-03-27)

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 DEERFIELD MANAGEMENT COMPANY, L.P. 18.00% of their portfolio New York, NY 19,991,02420.0m $843.0m $843.0m 18.00% Unchanged
2 FMR LLC 0.03% of their portfolio BOSTON, MA 7,618,1247.6m $321.3m $321.3m 0.03% Reduced -7.8m -7,762,724
3 Bain Capital Life Sciences Investors, LLC 15.54% of their portfolio Boston, MA 3,577,2673.6m $150.9m $150.9m 15.54% Unchanged
4 Fairmount Funds Management LLC 17.15% of their portfolio WEST CONSHOHOCKEN, PA 2,884,4922.9m $121.6m $121.6m 17.15% Unchanged
5 BlackRock Inc. 0.00% of their portfolio New York, NY 2,396,8642.4m $101.1m $101.1m 0.00% Added +201.0k +200,966
6 PERCEPTIVE ADVISORS LLC 2.69% of their portfolio NEW YORK, NY 2,194,8212.2m $92.6m $92.6m 2.69% Reduced -105.2k -105,227
7 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,118,4602.1m $89.3m $89.3m 0.00% Added +48.2k +48,214
8 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 1,736,4871.7m $73.2m $73.2m 0.01% Reduced -150.2k -150,189
9 Avoro Capital Advisors LLC 0.92% of their portfolio NEW YORK, NY 1,600,0001.6m $67.5m $67.5m 0.92% Reduced -288.9k -288,888
10 Driehaus Capital Management LLC 0.77% of their portfolio Chicago, IL 1,440,7301.4m $60.8m $60.8m 0.77% Added +38.2k +38,205
11 Boxer Capital, LLC 2.37% of their portfolio San Diego, CA 1,210,1921.2m $51.0m $51.0m 2.37% Unchanged
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,167,9891.2m $49.3m $49.3m 0.00% Added +124.8k +124,786
13 Commodore Capital LP 5.45% of their portfolio NEW YORK, NY 1,150,0001.1m $48.5m $48.5m 5.45% Added +75.0k +75,000
14 Paradigm Biocapital Advisors LP 3.82% of their portfolio NEW YORK, NY 1,120,4651.1m $47.3m $47.3m 3.82% New
15 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 575,678575.7k $24.3m $24.3m 0.00% Reduced -11.2k -11,182
16 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 528,491528.5k $22.3m $22.3m 0.00% Added +48.1k +48,108
17 ArrowMark Colorado Holdings LLC 0.18% of their portfolio Denver, CO 382,430382.4k $16.1m $16.1m 0.18% Added +14.0k +13,982
18 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 292,795292.8k $12.3m $12.3m 0.02% Added +80.6k +80,584
19 Candriam S.C.A. 0.09% of their portfolio STRASSEN, N4 280,016280.0k $11.8m $11.8m 0.09% Reduced -43.8k -43,835
20 Ikarian Capital, LLC 3.88% of their portfolio DALLAS, TX 272,752272.8k $11.5m $11.5m 3.88% New
21 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 245,154245.2k $10.3m $10.3m 0.00% Added +68.1k +68,062
22 Soleus Capital Management, L.P. 1.00% of their portfolio GREENWICH, CT 213,000213.0k $9.0m $9.0m 1.00% Reduced -23.9k -23,900
23 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 138,014138.0k $5.8m $5.8m 0.00% New
24 SILVERARC CAPITAL MANAGEMENT, LLC 1.64% of their portfolio BOSTON, MA 115,067115.1k $4.9m $4.9m 1.64% Reduced -166.5k -166,466
25 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 114,476114.5k $4.8m $4.8m 0.00% New
26 GREAT LAKES ADVISORS, LLC 0.04% of their portfolio CHICAGO, IL 103,712103.7k $4.4m $4.4m 0.04% New
27 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 87,82187.8k $3.7m $3.7m 0.00% Added +12.9k +12,911
28 Rhenman & Partners Asset Management AB 0.38% of their portfolio Stockholm, V7 86,01186.0k $3.6m $3.6m 0.38% Reduced -14.0k -13,989
29 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 82,72882.7k $3.5m $3.5m 0.00% Added +12.0k +12,036
30 Rafferty Asset Management, LLC 0.02% of their portfolio New York, NY 80,51880.5k $3.4m $3.4m 0.02% Added +12.1k +12,053
31 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 76,66976.7k $3.2m $3.2m 0.00% Added +4.2k +4,198
32 HighVista Strategies LLC 1.39% of their portfolio BOSTON, MA 72,29872.3k $3.0m $3.0m 1.39% Added +59.1k +59,093
33 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 66,69066.7k $2.8m $2.8m 0.00% Added +9.6k +9,575
34 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 61,02261.0k $2.6m $2.6m 0.00% Added +4.4k +4,402
35 JANUS HENDERSON GROUP PLC 0.00% of their portfolio LONDON, X0 56,91656.9k $2.4m $2.4m 0.00% Reduced -181.0k -181,038
36 BOOTHBAY FUND MANAGEMENT, LLC 0.07% of their portfolio NEW YORK, NY 55,29555.3k $2.3m $2.3m 0.07% New
37 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 50,93850.9k $2.1m $2.1m 0.00% Reduced -32.4k -32,371
38 Woodline Partners LP 0.02% of their portfolio San Francisco, CA 47,85047.9k $2.0m $2.0m 0.02% New
39 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 45,17045.2k $1.9m $1.9m 0.00% Added +19.5k +19,526
40 Swiss National Bank 0.00% of their portfolio ZURICH, V8 44,70044.7k $1.9m $1.9m 0.00% Reduced -4.8k -4,800
41 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 43,23343.2k $1.8m $1.8m 0.00% Added +11.7k +11,710
42 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 36,88136.9k $1.6m $1.6m 0.00% Reduced -380.3k -380,323
43 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 32,77132.8k $1.4m $1.4m 0.00% Added +456 +456
44 UBS Group AG 0.00% of their portfolio ZURICH, V8 31,77031.8k $1.3m $1.3m 0.00% Added +1.3k +1,329
45 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 30,99431.0k $1.3m $1.3m 0.00% Reduced -24.6k -24,637
46 Hudson Bay Capital Management LP 0.01% of their portfolio STAMFORD, CT 30,00030.0k $1.3m $1.3m 0.01% New
47 Informed Momentum Co LLC 0.22% of their portfolio SOLANA BEACH, CA 27,75427.8k $1.2m $1.2m 0.22% Unchanged
48 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 27,73727.7k $1.2m $1.2m 0.00% Added +4.1k +4,121
49 VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio San Antonio, TX 27,23327.2k $1.1m $1.1m 0.00% Reduced -5.4k -5,377
50 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 26,04026.0k $1.1m $1.1m 0.00% Reduced -1.6k -1,608
51 TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio STAMFORD, CT 25,68025.7k $1.1m $1.1m 0.02% Added +16.9k +16,932
52 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 24,59724.6k $1.0m $1.0m 0.00% Reduced -71 -71
53 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 23,61223.6k $995.7k $995.7k 0.00% Added +8.6k +8,589
54 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 23,30023.3k $982.6k $982.6k 0.00% Reduced -2.4k -2,431
55 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 23,30023.3k $982.6k $982.6k 0.00% Added +3.0k +3,000
56 Legal & General Group Plc 0.00% of their portfolio London, X0 22,46822.5k $947.5k $947.5k 0.00% Added +9.6k +9,615
57 M&T Bank Corp 0.00% of their portfolio BUFFALO, NY 20,89220.9k $881.5k $881.5k 0.00% Unchanged
58 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 20,00020.0k $857.0k $857.0k 0.00% Reduced -30.0k -30,000
59 TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.01% of their portfolio FRANKFORT, KY 19,88019.9k $838.0k $838.0k 0.01% Unchanged
60 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 15,93515.9k $672.0k $672.0k 0.00% New
61 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 15,10015.1k $636.8k $636.8k 0.00% Added +2.0k +2,000
62 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 14,98915.0k $632.1k $632.1k 0.00% Reduced -33.5k -33,492
63 PROFUND ADVISORS LLC 0.03% of their portfolio BETHESDA, MD 14,79514.8k $623.9k $623.9k 0.03% Added +1.9k +1,950
64 Jefferies Financial Group Inc. 0.01% of their portfolio NEW YORK, NY 14,60014.6k $615.7k $615.7k 0.01% New
65 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 14,35714.4k $605.4k $605.4k 0.00% New
66 SG Americas Securities, LLC 0.01% of their portfolio NEW YORK, NY 13,93613.9k $588.0k $588.0k 0.01% Added +5.1k +5,057
67 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 13,60013.6k $354.8k $354.8k 0.00% Unchanged
68 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 13,49313.5k $569.0k $569.0k 0.00% Reduced -2.1k -2,098
69 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 12,80812.8k $542.0k $542.0k 0.00% Added +66 +66
70 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 12,78212.8k $539.0k $539.0k 0.00% Added +1.9k +1,880
71 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 12,26212.3k $517.1k $517.1k 0.00% Unchanged
72 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 11,81411.8k $498.2k $498.2k 0.00% Reduced -4.8k -4,803
73 Ellsworth Advisors, LLC 0.17% of their portfolio HUDSON, OH 11,73211.7k $494.7k $494.7k 0.17% Added +380 +380
74 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 11,54411.5k $486.8k $486.8k 0.00% Added +1.8k +1,829
75 ADVISORY RESEARCH INC 0.06% of their portfolio CHICAGO, IL 11,32011.3k $477.4k $477.4k 0.06% Reduced -2.5k -2,508
76 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 10,70010.7k $451.0k $451.0k 0.00% Reduced -25.9k -25,900
77 FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 10,38310.4k $437.9k $437.9k 0.00% Reduced -341 -341
78 PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio DES MOINES, IA 9,6279.6k $406.0k $406.0k 0.00% Added +693 +693
79 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 9,5139.5k $401.2k $401.2k 0.00% New
80 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 9,2419.2k $389.7k $389.7k 0.00% New
81 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 9,1199.1k $384.5k $384.5k 0.00% Reduced -19.2k -19,230
82 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 8,5898.6k $362.2k $362.2k 0.00% New
83 Verition Fund Management LLC 0.01% of their portfolio GREENWICH, CT 7,8507.8k $331.0k $331.0k 0.01% New
84 Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio VANCOUVER, A1 7,8157.8k $329.6k $329.6k 0.00% New
85 MEITAV INVESTMENT HOUSE LTD 0.00% of their portfolio BENE-BERAQ, L3 7,0007.0k $414.9k $414.9k 0.00% New
86 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio TALLAHASSEE, FL 6,8106.8k $287.2k $287.2k 0.00% New
87 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 6,4436.4k $271.7k $271.7k 0.00% New
88 Old Well Partners, LLC 0.22% of their portfolio CHARLOTTE, NC 5,8005.8k $244.6k $244.6k 0.22% New
89 ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio PHOENIX, AZ 5,7665.8k $243.2k $243.2k 0.00% New
90 Ensign Peak Advisors, Inc 0.00% of their portfolio SALT LAKE CITY, UT 5,7005.7k $240.4k $240.4k 0.00% New
91 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio AUSTIN, TX 5,5775.6k $235.0k $235.0k 0.00% New
92 Atom Investors LP 0.08% of their portfolio AUSTIN, TX 5,1045.1k $215.2k $215.2k 0.08% Reduced -25.6k -25,556
93 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 4,9494.9k $208.9k $208.9k 0.00% New
94 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 3,5303.5k $149.0k $149.0k 0.00% Added +1.4k +1,411
95 EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio Oklahoma City, OK 3,2493.2k $137.0k $137.0k 0.00% New
96 VIRTUS ADVISERS, LLC 0.06% of their portfolio HARTFORD, CT 2,5242.5k $106.4k $106.4k 0.06% Reduced -603 -603
97 Allspring Global Investments Holdings, LLC 0.00% of their portfolio CHARLOTTE, NC 2,1712.2k $91.6k $91.6k 0.00% New
98 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 1,9812.0k $83.5k $83.5k 0.00% Added +550 +550
99 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 1,5331.5k $65.0k $65.0k 0.00% Added +398 +398
100 Metropolitan Life Insurance Co/NY 0.00% of their portfolio New York, NY 1,3251.3k $55.9k $55.9k 0.00% Added +246 +246