NEUROCRINE BIOSCIENCES INC NBIX
COM · Common Stock · CUSIP 64125C109 · ISIN US64125C1099
American biopharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Founded1992
- Websiteneurocrine.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($50.5m this quarter). Holder counts are more reliable. Shares outstanding: 101.2m as of 2024-10-24, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $115.27. Options: 18 managers hold calls ($83.4m notional), 17 hold puts ($77.4m).
Trends to Q3 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 466 |
| Q4 2022 | 530 |
| Q1 2023 | 488 |
| Q2 2023 | 457 |
| Q3 2023 | 514 |
| Q4 2023 | 555 |
| Q1 2024 | 591 |
| Q2 2024 | 595 |
| Q3 2024 | 576 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 282 | 209 |
| Q1 2023 | 253 | 249 |
| Q2 2023 | 199 | 257 |
| Q3 2023 | 242 | 227 |
| Q4 2023 | 270 | 242 |
| Q1 2024 | 310 | 256 |
| Q2 2024 | 325 | 257 |
| Q3 2024 | 296 | 286 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2023 | $64.4m | $54.6m | 0.85 |
| Q1 2024 | $88.0m | $61.6m | 0.70 |
| Q2 2024 | $129.5m | $57.7m | 0.45 |
| Q3 2024 | $83.4m | $77.4m | 0.93 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +1.0m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Added | +625.6k |
| AQR CAPITAL MANAGEMENT LLC | Added | +620.2k |
| STATE STREET CORP | Added | +539.9k |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Added | +363.9k |
| JUPITER ASSET MANAGEMENT LTD | Added | +275.7k |
| Amundi | Added | +265.4k |
| MACQUARIE GROUP LTD | Added | +221.2k |
| RENAISSANCE GROUP LLC | New | +204.1k |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | Added | +187.6k |
Biggest sellers
| JPMORGAN CHASE & CO | Reduced | -1.7m |
| ARMISTICE CAPITAL, LLC | Reduced | -797.1k |
| Polar Capital Holdings Plc | Reduced | -590.6k |
| 1832 Asset Management L.P. | Sold out | -541.2k |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Sold out | -484.8k |
| PERCEPTIVE ADVISORS LLC | Reduced | -437.7k |
| Invesco Ltd. | Reduced | -383.4k |
| AXA S.A. | Reduced | -298.9k |
| APG Asset Management N.V. | Sold out | -257.3k |
| Assenagon Asset Management S.A. | Reduced | -219.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $16.4m142.3k shares |
| JANE STREET GROUP, LLC | Added | $15.5m134.7k shares |
| LMR Partners LLP | Reduced | $15.4m133.4k shares |
| JPMORGAN CHASE & CO | Added | $8.1m70.0k shares |
| CITADEL ADVISORS LLC | Added | $5.4m47.0k shares |
| CITIGROUP INC | New | $5.3m45.8k shares |
| Caption Management, LLC | Added | $4.6m40.1k shares |
| GTS SECURITIES LLC | Added | $3.9m34.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $3.2m27.9k shares |
| Twin Tree Management, LP | New | $2.4m21.1k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $18.3m158.4k shares |
| Twin Tree Management, LP | Added | $14.3m124.3k shares |
| JANE STREET GROUP, LLC | Added | $8.7m75.8k shares |
| LMR Partners LLP | Reduced | $8.1m70.7k shares |
| JPMORGAN CHASE & CO | Unchanged | $6.9m60.0k shares |
| CITIGROUP INC | New | $6.9m59.5k shares |
| CITADEL ADVISORS LLC | Added | $5.5m47.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.5m21.4k shares |
| MILLENNIUM MANAGEMENT LLC | New | $2.2m18.7k shares |
| GTS SECURITIES LLC | Added | $2.1m18.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-28 | 12.1% |
| DODGE & COX 13G · institution new · filed 2025-05-14 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
| JPMORGAN CHASE & CO 13G · institution -1.1 pts · filed 2026-10-15 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q3 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2022 | 0 | — | 6 | $20.4m | — |
| Q1 2023 | 0 | — | 12 | $21.0m | — |
| Q2 2023 | 0 | — | 3 | $3.8m | $3.8m |
| Q3 2023 | 0 | — | 11 | $4.3m | $4.3m |
| Q4 2023 | 0 | — | 6 | $22.4m | $22.4m |
| Q1 2024 | 0 | — | 14 | $76.7m | $76.7m |
| Q2 2024 | 0 | — | 8 | $14.5m | $14.5m |
| Q3 2024 | 0 | — | 7 | $12.9m | $10.9m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-09-13 | Boyer David W. Chief Corp. Affairs Officer | Sold plan | $421.8k3.5k shares |
| 2024-08-15 | RASTETTER WILLIAM H Director | Sold | $2.1m14.2k shares |
| 2024-08-13 | ABERNETHY MATT Chief Financial Officer | Sold plan | $2.1m14.1k shares |
| 2024-08-13 | LYONS GARY A Director | Sold plan | $1.7m11.6k shares |
| 2024-08-13 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $1.1m7.1k shares |
| 2024-08-06 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $40.3k273 shares |
| 2024-08-01 | Cooke Julie Chief Human Resources Officer | Sold plan | $1.9m12.6k shares |
| 2024-08-01 | Lippoldt Darin Chief Legal Officer | Sold plan | $461.4k3.0k shares |
| 2024-07-16 | Lippoldt Darin Chief Legal Officer | Sold plan | $1.1m7.0k shares |
| 2024-07-16 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $428.6k2.9k shares |
| 2024-07-16 | LYONS GARY A Director | Sold plan | $139.5k930 shares |
| 2024-07-16 | ABERNETHY MATT Chief Financial Officer | Sold plan | $135.0k900 shares |
| 2024-07-16 | Cooke Julie Chief Human Resources Officer | Sold plan | $135.0k900 shares |
| 2024-07-01 | Cooke Julie Chief Human Resources Officer | Sold plan | $1.4m10.0k shares |
| 2024-07-01 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $37.6k272 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.03% of their portfolio | 14.3m $1.6bn | First filing |
| VANGUARD GROUP INC 0.02% of their portfolio | 10.0m $1.2bn | Reduced -59.5k |
| STATE STREET CORP 0.02% of their portfolio | 5.1m $593.2m | Added +539.9k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 3.0m $345.2m | Reduced -1.7m |
| RENAISSANCE TECHNOLOGIES LLC 0.45% of their portfolio | 2.6m $296.6m | Added +106.4k |
| Bellevue Group AG 3.48% of their portfolio | 1.9m $214.7m | Reduced -34.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.9m $213.8m | Added +39.6k |
| AQR CAPITAL MANAGEMENT LLC 0.29% of their portfolio | 1.8m $212.2m | Added +620.2k |
| CITADEL ADVISORS LLC 0.21% of their portfolio | 1.8m $203.3m | Added +1.0m |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 1.7m $193.0m | Reduced -123.7k |
| MORGAN STANLEY 0.01% of their portfolio | 1.3m $155.5m | Reduced -195.5k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 2.27% of their portfolio | 1.3m $151.7m | Added +625.6k |
| Dodge & Cox 0.08% of their portfolio | 1.3m $148.4m | Added +7.0k |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 1.0m $117.2m | Reduced -115.4k |
| DSM CAPITAL PARTNERS LLC 1.66% of their portfolio | 944.2k $108.8m | Reduced -53.6k |
| BROWN ADVISORY INC 0.14% of their portfolio | 942.1k $108.6m | Reduced -53.1k |
| Rock Springs Capital Management LP 3.52% of their portfolio | 939.0k $108.2m | Reduced -1.0k |
| BRAIDWELL LP 3.00% of their portfolio | 917.7k $105.7m | Added +158.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio | 894.2k $103.0m | Reduced -17.8k |
| Invesco Ltd. 0.02% of their portfolio | 874.7k $100.8m | Reduced -383.4k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 858.2k $98.9m | Reduced -76.2k |
| Pictet Asset Management Holding SA 0.11% of their portfolio | 842.2k $97.0m | Reduced -29.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.23% of their portfolio | 820.0k $94.5m | Added +37.1k |
| JANUS HENDERSON GROUP PLC 0.05% of their portfolio | 792.2k $91.3m | Reduced -179.0k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 771.6k $88.9m | Reduced -39.0k |
| Qube Research & Technologies Ltd 0.16% of their portfolio | 763.4k $88.0m | Added +161.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 747.3k $86.1m | Reduced -5.2k |
| Caisse de depot et placement du Quebec 0.17% of their portfolio | 736.9k $84.9m | Added +80.8k |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 718.2k $82.8m | Reduced -181.3k |
| Allspring Global Investments Holdings, LLC 0.12% of their portfolio | 690.0k $79.5m | Reduced -20.6k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 664.3k $77.4m | Reduced -144.1k |
| Amundi 0.03% of their portfolio | 656.7k $73.3m | Added +265.4k |
| ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio | 636.9k $73.4m | Added +15.0k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 623.6k $71.8m | Added +4.7k |
| EAGLE ASSET MANAGEMENT INC 0.40% of their portfolio | 621.4k $78.1m | Reduced -58.7k |
| JUPITER ASSET MANAGEMENT LTD 0.59% of their portfolio | 582.8k $67.1m | Added +275.7k |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 544.3k $62.7m | Added +110.8k |
| BNP PARIBAS FINANCIAL MARKETS 0.06% of their portfolio | 533.3k $61.4m | Added +102.7k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.23% of their portfolio | 524.2k $60.4m | Reduced -196.9k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 523.6k $60.3m | Added +50.7k |
| Fiera Capital Corp 0.18% of their portfolio | 516.8k $59.5m | Reduced -11.1k |
| IEQ CAPITAL, LLC 0.72% of their portfolio | 512.5k $59.0m | Added +6.4k |
| GW&K Investment Management, LLC 0.50% of their portfolio | 510.1k $58.8m | Reduced -36.0k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 496.1k $57.2m | Added +82.9k |
| MACQUARIE GROUP LTD 0.06% of their portfolio | 492.2k $56.7m | Added +221.2k |
| Candriam S.C.A. 0.32% of their portfolio | 483.2k $55.7m | Added +17.8k |
| California Public Employees Retirement System 0.04% of their portfolio | 462.1k $53.2m | Reduced -22.9k |
| Avidity Partners Management LP 2.70% of their portfolio | 460.0k $53.0m | Reduced -31.0k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 437.8k $50.4m | Added +4.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.20% of their portfolio | 420.7k $48.5m | Added +363.9k |
| Sarissa Capital Management LP 11.76% of their portfolio | 410.5k $47.3m | Unchanged |
| PRIMECAP MANAGEMENT CO/CA/ 0.03% of their portfolio | 404.0k $46.5m | Reduced -5.3k |
| Legal & General Group Plc 0.01% of their portfolio | 390.6k $45.0m | Reduced -11.9k |
| Robeco Institutional Asset Management B.V. 0.09% of their portfolio | 387.3k $44.6m | Added +53.3k |
| UBS Group AG 0.01% of their portfolio | 359.6k $41.4m | Added +42.6k |
| NORGES BANK 0.01% of their portfolio | 351.1k $40.4m | Reduced -98.5k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 345.6k $39.8m | Reduced -1.9k |
| JENNISON ASSOCIATES LLC 0.02% of their portfolio | 334.8k $38.6m | Reduced -164.5k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 321.7k $37.1m | Reduced -2.5k |
| Clearbridge Investments, LLC 0.03% of their portfolio | 319.3k $36.8m | Reduced -21.5k |
| MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio | 312.8k $36.0m | Added +125.3k |
| Skandinaviska Enskilda Banken AB (publ) 0.16% of their portfolio | 303.8k $35.0m | Added +184.0k |
| ORBIMED ADVISORS LLC 0.64% of their portfolio | 302.2k $34.8m | Reduced -146.0k |
| Swiss National Bank 0.02% of their portfolio | 298.7k $34.4m | Added +4.1k |
| Man Group plc 0.10% of their portfolio | 296.2k $34.1m | Added +63.0k |
| AXA S.A. 0.09% of their portfolio | 269.2k $31.0m | Reduced -298.9k |
| Hood River Capital Management LLC 0.49% of their portfolio | 263.2k $30.3m | Added +19.3k |
| WELLS FARGO & COMPANY/MN 0.01% of their portfolio | 260.4k $30.0m | Added +25.4k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 253.2k $29.2m | Reduced -120.6k |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 252.9k $29.1m | Added +87.5k |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 3.95% of their portfolio | 247.0k $28.5m | Added +187.6k |
| FMR LLC 0.00% of their portfolio | 246.1k $28.4m | Reduced -95.7k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 233.5k $26.9m | Added +30.7k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 231.9k $26.7m | Reduced -11.5k |
| HSBC HOLDINGS PLC 0.02% of their portfolio | 223.3k $25.7m | Added +110.2k |
| TRUIST FINANCIAL CORP 0.04% of their portfolio | 214.3k $24.7m | Added +182.7k |
| PERCEPTIVE ADVISORS LLC 0.52% of their portfolio | 212.2k $24.5m | Reduced -437.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.02% of their portfolio | 211.3k $24.3m | Added +25.9k |
| Russell Investments Group, Ltd. 0.04% of their portfolio | 210.8k $24.3m | Reduced -78.0k |
| VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio | 204.2k $23.5m | Added +66.7k |
| RENAISSANCE GROUP LLC 0.97% of their portfolio | 204.1k $23.5m | New |
| SCOUT INVESTMENTS, INC. 0.62% of their portfolio | 203.5k $23.5m | Added +13.6k |
| CITIGROUP INC 0.02% of their portfolio | 200.5k $23.1m | Added +84.2k |
| TWINBEECH CAPITAL LP 0.40% of their portfolio | 182.1k $21.0m | Added +130.9k |
| BARCLAYS PLC 0.01% of their portfolio | 181.6k $20.9m | Added +19.2k |
| ARMISTICE CAPITAL, LLC 0.55% of their portfolio | 181.4k $20.9m | Reduced -797.1k |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 181.2k $20.9m | Reduced -17.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio | 179.8k $20.7m | Reduced -28.6k |
| Andra AP-fonden 0.30% of their portfolio | 177.9k $20.5m | Added +16.6k |
| PRUDENTIAL FINANCIAL INC 0.03% of their portfolio | 176.7k $20.4m | Reduced -17.5k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 174.8k $20.1m | Reduced -97.8k |
| D. E. Shaw & Co., Inc. 0.03% of their portfolio | 169.5k $19.5m | Added +61.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 163.1k $18.8m | Added +7.1k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 159.5k $18.4m | Added +35.8k |
| SEI INVESTMENTS CO 0.02% of their portfolio | 155.1k $17.9m | Added +27.1k |
| LOOMIS SAYLES & CO L P 0.02% of their portfolio | 150.3k $17.3m | Reduced -9.9k |
| SOROS FUND MANAGEMENT LLC 0.34% of their portfolio | 150.0k $17.3m | Reduced -44.8k |
| TANG CAPITAL MANAGEMENT LLC 1.23% of their portfolio | 150.0k $17.3m | New |
| Rafferty Asset Management, LLC 0.06% of their portfolio | 140.8k $16.2m | Added +17.8k |
| Federation des caisses Desjardins du Quebec 0.08% of their portfolio | 139.5k $16.1m | Added +29.8k |