NEUROCRINE BIOSCIENCES INC NBIX
COM · Common Stock · CUSIP 64125C109 · ISIN US64125C1099
American biopharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Founded1992
- Websiteneurocrine.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($66.5m this quarter). Holder counts are more reliable. Shares outstanding: 101.0m as of 2024-07-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $137.63. Options: 18 managers hold calls ($129.5m notional), 14 hold puts ($57.7m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 466 |
| Q4 2022 | 530 |
| Q1 2023 | 488 |
| Q2 2023 | 457 |
| Q3 2023 | 514 |
| Q4 2023 | 555 |
| Q1 2024 | 591 |
| Q2 2024 | 595 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 282 | 209 |
| Q1 2023 | 253 | 249 |
| Q2 2023 | 199 | 257 |
| Q3 2023 | 242 | 227 |
| Q4 2023 | 270 | 242 |
| Q1 2024 | 310 | 256 |
| Q2 2024 | 325 | 257 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $71.2m | $54.7m | 0.77 |
| Q4 2023 | $64.4m | $54.6m | 0.85 |
| Q1 2024 | $88.0m | $61.6m | 0.70 |
| Q2 2024 | $129.5m | $57.7m | 0.45 |
Biggest buyers
| STATE STREET CORP | Added | +618.4k |
| Caisse de depot et placement du Quebec | Added | +504.4k |
| 1832 Asset Management L.P. | Added | +504.4k |
| ALLIANCEBERNSTEIN L.P. | Added | +461.6k |
| BlackRock Inc. | Added | +429.7k |
| GOLDMAN SACHS GROUP INC | Added | +356.9k |
| Qube Research & Technologies Ltd | Added | +349.9k |
| AXA S.A. | Added | +324.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +312.6k |
| AQR CAPITAL MANAGEMENT LLC | Added | +228.4k |
Biggest sellers
| MORGAN STANLEY | Reduced | -4.7m |
| Point72 Asset Management, L.P. | Sold out | -837.4k |
| LORD, ABBETT & CO. LLC | Reduced | -713.6k |
| Vestal Point Capital, LP | Sold out | -710.0k |
| JANUS HENDERSON GROUP PLC | Reduced | -407.3k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -267.7k |
| PANAGORA ASSET MANAGEMENT INC | Reduced | -260.0k |
| Pictet Asset Management Holding SA | Reduced | -210.1k |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Reduced | -188.5k |
| National Pension Service | Reduced | -174.2k |
Biggest calls
| LMR Partners LLP | Added | $29.2m211.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $22.7m164.7k shares |
| MILLENNIUM MANAGEMENT LLC | New | $14.8m107.5k shares |
| Ikarian Capital, LLC | New | $13.8m1.0k shares |
| JANE STREET GROUP, LLC | Added | $9.9m71.8k shares |
| JPMORGAN CHASE & CO | New | $8.3m60.0k shares |
| BARCLAYS PLC | New | $8.3m60.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $5.5m40.1k shares |
| CITADEL ADVISORS LLC | Reduced | $5.0m36.3k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | New | $4.2m30.3k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $10.9m79.2k shares |
| LMR Partners LLP | Added | $10.7m77.7k shares |
| SIMPLEX TRADING, LLC | Added | $9.3m67.5k shares |
| JPMORGAN CHASE & CO | New | $8.3m60.0k shares |
| JANE STREET GROUP, LLC | Reduced | $6.5m47.4k shares |
| CITADEL ADVISORS LLC | Added | $3.9m28.1k shares |
| GROUP ONE TRADING LLC | Added | $2.3m16.9k shares |
| Twin Tree Management, LP | New | $1.9m14.1k shares |
| GTS SECURITIES LLC | New | $1.4m9.9k shares |
| Walleye Capital LLC | Added | $1.1m8.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-28 | 12.1% |
| DODGE & COX 13G · institution new · filed 2025-05-14 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
| JPMORGAN CHASE & CO 13G · institution -1.1 pts · filed 2026-10-15 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 2 | $2.5m | — |
| Q4 2022 | 0 | — | 6 | $20.4m | — |
| Q1 2023 | 0 | — | 12 | $21.0m | — |
| Q2 2023 | 0 | — | 3 | $3.8m | $3.8m |
| Q3 2023 | 0 | — | 11 | $4.3m | $4.3m |
| Q4 2023 | 0 | — | 6 | $22.4m | $22.4m |
| Q1 2024 | 0 | — | 14 | $76.7m | $76.7m |
| Q2 2024 | 0 | — | 8 | $14.5m | $14.5m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-05-31 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $37.3k273 shares |
| 2024-05-29 | SHERWIN STEPHEN A Director | Sold plan | $5.3m40.0k shares |
| 2024-05-17 | POPS RICHARD F Director | Sold plan | $297.9k2.1k shares |
| 2024-05-17 | Sharp Shalini Director | Sold plan | $156.9k1.1k shares |
| 2024-05-17 | Norwalk Leslie V Director | Sold plan | $156.9k1.1k shares |
| 2024-05-15 | ABERNETHY MATT Chief Financial Officer | Sold plan | $2.1m15.0k shares |
| 2024-05-14 | ABERNETHY MATT Chief Financial Officer | Sold plan | $2.0m15.0k shares |
| 2024-05-14 | LYONS GARY A Director | Sold plan | $1.7m12.5k shares |
| 2024-05-06 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $38.4k273 shares |
| 2024-04-15 | BENEVICH ERIC Chief Commercial Officer | Sold plan | $2.6m19.8k shares |
| 2024-04-01 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $37.3k272 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.04% of their portfolio | 14.2m $2.0bn | Added +429.7k |
| VANGUARD GROUP INC 0.03% of their portfolio | 10.1m $1.4bn | Added +125.5k |
| JPMORGAN CHASE & CO 0.03% of their portfolio | 4.7m $650.6m | Added +135.3k |
| STATE STREET CORP 0.03% of their portfolio | 4.6m $634.4m | Added +618.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.58% of their portfolio | 2.5m $339.8m | Added +216.5k |
| Bellevue Group AG 4.25% of their portfolio | 1.9m $261.4m | Reduced -157.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.8m $250.1m | Added +105.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.03% of their portfolio | 1.8m $247.6m | Reduced -21.9k |
| MORGAN STANLEY 0.02% of their portfolio | 1.5m $212.7m | Reduced -4.7m |
| Dodge & Cox 0.11% of their portfolio | 1.3m $176.3m | Added +15.6k |
| Invesco Ltd. 0.04% of their portfolio | 1.3m $173.2m | Added +121.2k |
| AQR CAPITAL MANAGEMENT LLC 0.26% of their portfolio | 1.2m $167.0m | Added +228.4k |
| GOLDMAN SACHS GROUP INC 0.03% of their portfolio | 1.1m $155.9m | Added +356.9k |
| DSM CAPITAL PARTNERS LLC 1.99% of their portfolio | 997.8k $137.4m | Reduced -138.2k |
| BROWN ADVISORY INC 0.18% of their portfolio | 995.2k $137.0m | Reduced -93.1k |
| ARMISTICE CAPITAL, LLC 3.52% of their portfolio | 978.5k $134.7m | Reduced -45.3k |
| JANUS HENDERSON GROUP PLC 0.07% of their portfolio | 971.2k $133.7m | Reduced -407.3k |
| Rock Springs Capital Management LP 3.91% of their portfolio | 940.0k $129.4m | Reduced -114.9k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 934.4k $128.6m | Added +13.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% of their portfolio | 912.1k $125.6m | Added +312.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 899.5k $123.8m | Reduced -104.3k |
| Pictet Asset Management Holding SA 0.14% of their portfolio | 871.3k $120.0m | Reduced -210.1k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 810.6k $111.6m | Added +95.6k |
| FRANKLIN RESOURCES INC 0.03% of their portfolio | 808.5k $111.3m | Added +14.6k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.28% of their portfolio | 782.9k $107.8m | Reduced -7.3k |
| BRAIDWELL LP 3.28% of their portfolio | 759.0k $104.5m | Added +28.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 752.5k $103.6m | Added +27.3k |
| CITADEL ADVISORS LLC 0.10% of their portfolio | 740.9k $102.0m | Reduced -100.4k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.41% of their portfolio | 721.1k $99.3m | Added +8.3k |
| Allspring Global Investments Holdings, LLC 0.16% of their portfolio | 710.6k $97.8m | Added +203.9k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 1.58% of their portfolio | 691.0k $95.1m | Unchanged |
| EAGLE ASSET MANAGEMENT INC 0.51% of their portfolio | 680.0k $95.3m | Reduced -33.5k |
| Caisse de depot et placement du Quebec 0.22% of their portfolio | 656.1k $90.3m | Added +504.4k |
| PERCEPTIVE ADVISORS LLC 2.16% of their portfolio | 649.9k $89.5m | Reduced -154.5k |
| ALLIANCEBERNSTEIN L.P. 0.03% of their portfolio | 621.9k $85.6m | Added +461.6k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 618.9k $85.2m | Added +52.2k |
| Polar Capital Holdings Plc 0.50% of their portfolio | 610.6k $84.1m | Reduced -165.0k |
| Qube Research & Technologies Ltd 0.15% of their portfolio | 601.7k $82.8m | Added +349.9k |
| AXA S.A. 0.12% of their portfolio | 568.0k $78.2m | Added +324.4k |
| GW&K Investment Management, LLC 0.69% of their portfolio | 546.1k $75.2m | Added +18.2k |
| 1832 Asset Management L.P. 0.13% of their portfolio | 541.2k $74.5m | Added +504.4k |
| Fiera Capital Corp 0.23% of their portfolio | 527.9k $72.7m | Added +16.4k |
| IEQ CAPITAL, LLC 0.94% of their portfolio | 506.1k $69.7m | Reduced -27 |
| JENNISON ASSOCIATES LLC 0.04% of their portfolio | 499.3k $68.7m | Added +153.9k |
| Avidity Partners Management LP 2.87% of their portfolio | 491.0k $67.6m | Reduced -45.5k |
| California Public Employees Retirement System 0.05% of their portfolio | 485.0k $66.8m | Reduced -95.6k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.33% of their portfolio | 484.8k $66.7m | Reduced -18.4k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 472.9k $65.1m | Added +147.9k |
| Candriam S.C.A. 0.39% of their portfolio | 465.5k $64.1m | Added +149.8k |
| NORGES BANK 0.01% of their portfolio | 449.6k $61.9m | Added +24.3k |
| ORBIMED ADVISORS LLC 1.23% of their portfolio | 448.2k $61.7m | Added +25.1k |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 433.5k $59.7m | Reduced -93.0k |
| DEUTSCHE BANK AG\ 0.03% of their portfolio | 433.1k $59.6m | Added +73.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.06% of their portfolio | 430.6k $59.3m | Reduced -1.4k |
| AMERIPRISE FINANCIAL INC 0.02% of their portfolio | 413.2k $56.9m | Added +7.8k |
| Sarissa Capital Management LP 9.54% of their portfolio | 410.5k $56.5m | Added +64.1k |
| PRIMECAP MANAGEMENT CO/CA/ 0.04% of their portfolio | 409.3k $56.3m | Added +9.9k |
| Legal & General Group Plc 0.02% of their portfolio | 402.5k $55.4m | Reduced -117 |
| Amundi 0.02% of their portfolio | 391.3k $54.1m | Added +29.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.03% of their portfolio | 373.8k $51.5m | Reduced -44.9k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 347.5k $47.8m | Reduced -9.7k |
| FMR LLC 0.00% of their portfolio | 341.8k $47.1m | Added +109.3k |
| Clearbridge Investments, LLC 0.04% of their portfolio | 340.8k $46.9m | Unchanged |
| Robeco Institutional Asset Management B.V. 0.10% of their portfolio | 334.0k $46.0m | Added +23.8k |
| RHUMBLINE ADVISERS 0.04% of their portfolio | 324.3k $44.6m | Added +2.2k |
| UBS Group AG 0.01% of their portfolio | 316.9k $43.6m | Added +81.3k |
| JUPITER ASSET MANAGEMENT LTD 0.40% of their portfolio | 307.1k $42.3m | Added +88.6k |
| Swiss National Bank 0.03% of their portfolio | 294.6k $40.6m | Added +400 |
| Russell Investments Group, Ltd. 0.06% of their portfolio | 288.8k $39.7m | Reduced -60.6k |
| Ensign Peak Advisors, Inc 0.07% of their portfolio | 272.6k $37.5m | Added +117.9k |
| MACQUARIE GROUP LTD 0.04% of their portfolio | 271.0k $37.3m | Reduced -5.0k |
| APG Asset Management N.V. 0.06% of their portfolio | 257.3k $33.1m | Reduced -119.8k |
| Assenagon Asset Management S.A. 0.09% of their portfolio | 249.4k $34.3m | Reduced -88.3k |
| Hood River Capital Management LLC 0.70% of their portfolio | 243.9k $33.6m | Added +15.9k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 243.4k $33.5m | Reduced -9.1k |
| WELLS FARGO & COMPANY/MN 0.01% of their portfolio | 235.0k $32.3m | Added +13.2k |
| Man Group plc 0.08% of their portfolio | 233.2k $32.1m | Reduced -56.5k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio | 208.4k $28.7m | Added +2.0k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 202.8k $27.9m | Added +3.4k |
| Iron Triangle Partners LP 2.89% of their portfolio | 200.0k $27.5m | Reduced -20.0k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 198.5k $27.3m | Reduced -28.5k |
| SOROS FUND MANAGEMENT LLC 0.60% of their portfolio | 194.8k $26.8m | Added +35.0k |
| PRUDENTIAL FINANCIAL INC 0.04% of their portfolio | 194.3k $26.7m | Added +78.1k |
| SCOUT INVESTMENTS, INC. 0.70% of their portfolio | 189.9k $26.1m | Added +83.3k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 187.5k $25.8m | Reduced -267.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.03% of their portfolio | 185.4k $25.5m | Added +35.3k |
| Holocene Advisors, LP 0.11% of their portfolio | 185.3k $25.5m | New |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 165.4k $22.8m | Added +26.5k |
| BARCLAYS PLC 0.01% of their portfolio | 162.4k $22.4m | Reduced -94.8k |
| Andra AP-fonden 0.37% of their portfolio | 161.3k $22.2m | Added +86.9k |
| Aberdeen Group plc 0.04% of their portfolio | 161.1k $22.2m | Added +77.9k |
| LOOMIS SAYLES & CO L P 0.03% of their portfolio | 160.3k $22.1m | Reduced -94.7k |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.20% of their portfolio | 158.5k $21.8m | Added +89.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 156.0k $21.5m | Added +4.1k |
| COMERICA BANK 0.09% of their portfolio | 152.8k $21.0m | Added +17.2k |
| VOYA INVESTMENT MANAGEMENT LLC 0.02% of their portfolio | 151.5k $20.9m | Added +2.5k |
| TD Asset Management Inc 0.02% of their portfolio | 140.3k $19.3m | Reduced -3.2k |
| BANCO BILBAO VIZCAYA ARGENTARIA, S.A. 0.20% of their portfolio | 138.8k $19.1m | Unchanged |
| DANSKE BANK A/S 0.07% of their portfolio | 138.4k $19.1m | Added +4.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 137.8k $19.0m | Reduced -6.6k |