NEUROCRINE BIOSCIENCES INC NBIX
COM · Common Stock · CUSIP 64125C109 · ISIN US64125C1099
American biopharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Founded1992
- Websiteneurocrine.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($51.5m this quarter). Holder counts are more reliable. Shares outstanding: 100.6m as of 2024-04-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $137.84. Options: 14 managers hold calls ($88.0m notional), 16 hold puts ($61.6m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 466 |
| Q4 2022 | 530 |
| Q1 2023 | 488 |
| Q2 2023 | 457 |
| Q3 2023 | 514 |
| Q4 2023 | 555 |
| Q1 2024 | 591 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 282 | 209 |
| Q1 2023 | 253 | 249 |
| Q2 2023 | 199 | 257 |
| Q3 2023 | 242 | 227 |
| Q4 2023 | 270 | 242 |
| Q1 2024 | 310 | 256 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $51.6m | $37.7m | 0.73 |
| Q3 2023 | $71.2m | $54.7m | 0.77 |
| Q4 2023 | $64.4m | $54.6m | 0.85 |
| Q1 2024 | $88.0m | $61.6m | 0.70 |
Biggest buyers
| MORGAN STANLEY | Added | +1.5m |
| JPMORGAN CHASE & CO | Added | +1.1m |
| CITADEL ADVISORS LLC | Added | +729.3k |
| LORD, ABBETT & CO. LLC | Added | +688.5k |
| PERCEPTIVE ADVISORS LLC | Added | +533.6k |
| Invesco Ltd. | Added | +463.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +343.8k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +263.1k |
| AQR CAPITAL MANAGEMENT LLC | Added | +255.8k |
| JANE STREET GROUP, LLC | Added | +238.1k |
Biggest sellers
| LOS ANGELES CAPITAL MANAGEMENT LLC | Reduced | -673.0k |
| AMERICAN CENTURY COMPANIES INC | Reduced | -555.0k |
| Point72 Asset Management, L.P. | Reduced | -554.5k |
| Bellevue Group AG | Reduced | -374.6k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -233.7k |
| PRUDENTIAL FINANCIAL INC | Reduced | -213.3k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Reduced | -205.7k |
| Balyasny Asset Management L.P. | Reduced | -203.1k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -195.8k |
| JANUS HENDERSON GROUP PLC | Reduced | -172.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $24.8m179.9k shares |
| LMR Partners LLP | New | $22.3m161.5k shares |
| SIMPLEX TRADING, LLC | Added | $6.7m48.9k shares |
| GROUP ONE TRADING LLC | Added | $5.9m43.1k shares |
| JANE STREET GROUP, LLC | Added | $5.6m40.8k shares |
| CITADEL ADVISORS LLC | Reduced | $5.4m39.0k shares |
| Portman Square Capital LLP | Unchanged | $4.6m33.2k shares |
| CITIGROUP INC | Unchanged | $4.1m30.0k shares |
| Walleye Capital LLC | New | $3.4m24.3k shares |
| PEAK6 Investments LLC | Added | $2.5m18.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $15.1m109.8k shares |
| Portman Square Capital LLP | Unchanged | $13.2m95.6k shares |
| JANE STREET GROUP, LLC | Added | $10.3m74.6k shares |
| CITIGROUP INC | Unchanged | $4.1m30.0k shares |
| TORNO CAPITAL, LLC | New | $4.1m30.0k shares |
| Caption Management, LLC | Reduced | $3.4m25.0k shares |
| LMR Partners LLP | New | $2.6m19.1k shares |
| SIMPLEX TRADING, LLC | Added | $2.5m18.3k shares |
| CITADEL ADVISORS LLC | Added | $2.0m14.2k shares |
| GROUP ONE TRADING LLC | Added | $1.4m10.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-28 | 12.1% |
| DODGE & COX 13G · institution new · filed 2025-05-14 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
| JPMORGAN CHASE & CO 13G · institution -1.1 pts · filed 2026-10-15 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 4 | $3.6m | — |
| Q3 2022 | 0 | — | 2 | $2.5m | — |
| Q4 2022 | 0 | — | 6 | $20.4m | — |
| Q1 2023 | 0 | — | 12 | $21.0m | — |
| Q2 2023 | 0 | — | 3 | $3.8m | $3.8m |
| Q3 2023 | 0 | — | 11 | $4.3m | $4.3m |
| Q4 2023 | 0 | — | 6 | $22.4m | $22.4m |
| Q1 2024 | 0 | — | 14 | $76.7m | $76.7m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-03-21 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $725.3k5.0k shares |
| 2024-03-14 | BENEVICH ERIC Chief Commercial Officer | Sold plan | $10.5m75.0k shares |
| 2024-03-14 | MORROW GEORGE J Director | Sold plan | $5.6m40.0k shares |
| 2024-03-13 | POPS RICHARD F Director | Sold plan | $3.3m23.2k shares |
| 2024-03-13 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $420.4k3.0k shares |
| 2024-03-11 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $28.0k200 shares |
| 2024-03-11 | POPS RICHARD F Director | Sold plan | $14.0k100 shares |
| 2024-03-08 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $252.1k1.8k shares |
| 2024-03-08 | POPS RICHARD F Director | Sold plan | $238.1k1.7k shares |
| 2024-02-29 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $37.0k273 shares |
| 2024-02-28 | BENEVICH ERIC Chief Commercial Officer | Sold plan | $10.1m75.0k shares |
| 2024-02-28 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $885.6k6.5k shares |
| 2024-02-27 | Norwalk Leslie V Director | Sold plan | $1.1m8.0k shares |
| 2024-02-20 | POPS RICHARD F Director | Sold plan | $2.0m15.0k shares |
| 2024-02-13 | GORMAN KEVIN CHARLES Chief Executive Officer, director | Sold plan | $376.7k2.8k shares |
| 2024-02-13 | Boyer David W. Chief Corp. Affairs Officer | Sold plan | $241.0k1.8k shares |
| 2024-02-13 | Onyia Jude Chief Scientific Officer | Sold plan | $190.4k1.4k shares |
| 2024-02-13 | Gano Kyle Chief Business Development Off | Sold plan | $179.7k1.4k shares |
| 2024-02-13 | ABERNETHY MATT Chief Financial Officer | Sold plan | $179.6k1.4k shares |
| 2024-02-13 | ROBERTS EIRY Chief Medical Officer | Sold plan | $148.1k1.1k shares |
| 2024-02-13 | BENEVICH ERIC Chief Commercial Officer | Sold plan | $146.0k1.1k shares |
| 2024-02-13 | Lippoldt Darin Chief Legal Officer | Sold plan | $146.0k1.1k shares |
| 2024-02-13 | Cooke Julie Chief Human Resources Officer | Sold plan | $105.9k796 shares |
| 2024-02-13 | Delaet Ingrid Chief Regulatory Officer | Sold plan | $95.2k716 shares |
| 2024-02-08 | GORMAN KEVIN CHARLES Chief Executive Officer, director | Sold plan | $305.1k2.3k shares |
| 2024-02-08 | Cooke Julie Chief Human Resources Officer | Sold plan | $180.0k1.3k shares |
| 2024-02-08 | Boyer David W. Chief Corp. Affairs Officer | Sold plan | $179.8k1.3k shares |
| 2024-02-08 | ROBERTS EIRY Chief Medical Officer | Sold plan | $131.5k980 shares |
| 2024-02-08 | ABERNETHY MATT Chief Financial Officer | Sold plan | $131.5k980 shares |
| 2024-02-08 | Gano Kyle Chief Business Development Off | Sold plan | $131.5k980 shares |
The latest 30 of 56 trades.
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.04% of their portfolio | 13.8m $1.9bn | Added +113.1k |
| VANGUARD GROUP INC 0.03% of their portfolio | 9.9m $1.4bn | Added +220.6k |
| MORGAN STANLEY 0.02% of their portfolio | 6.2m $854.7m | Added +1.5m |
| JPMORGAN CHASE & CO 0.03% of their portfolio | 4.6m $633.1m | Added +1.1m |
| STATE STREET CORP 0.02% of their portfolio | 4.0m $550.3m | Reduced -73.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.49% of their portfolio | 2.3m $310.5m | Added +263.1k |
| Bellevue Group AG 4.32% of their portfolio | 2.1m $283.5m | Reduced -374.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.03% of their portfolio | 1.8m $251.1m | Added +343.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.7m $236.0m | Added +90.6k |
| JANUS HENDERSON GROUP PLC 0.10% of their portfolio | 1.4m $190.1m | Reduced -172.9k |
| Dodge & Cox 0.10% of their portfolio | 1.3m $174.5m | Added +5.5k |
| Invesco Ltd. 0.03% of their portfolio | 1.1m $156.8m | Added +463.1k |
| DSM CAPITAL PARTNERS LLC 2.14% of their portfolio | 1.1m $156.7m | Reduced -86.0k |
| BROWN ADVISORY INC 0.20% of their portfolio | 1.1m $150.1m | Reduced -25.1k |
| Pictet Asset Management Holding SA 0.16% of their portfolio | 1.1m $149.1m | Reduced -131.9k |
| Rock Springs Capital Management LP 3.70% of their portfolio | 1.1m $145.5m | Reduced -141.1k |
| ARMISTICE CAPITAL, LLC 3.76% of their portfolio | 1.0m $141.2m | Reduced -24.3k |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 1.0m $138.4m | Reduced -195.8k |
| AQR CAPITAL MANAGEMENT LLC 0.23% of their portfolio | 994.6k $137.2m | Added +255.8k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 921.3k $127.1m | Reduced -57.7k |
| CITADEL ADVISORS LLC 0.11% of their portfolio | 841.3k $116.0m | Added +729.3k |
| Point72 Asset Management, L.P. 0.34% of their portfolio | 837.4k $115.5m | Reduced -554.5k |
| PERCEPTIVE ADVISORS LLC 1.96% of their portfolio | 804.4k $110.9m | Added +533.6k |
| FRANKLIN RESOURCES INC 0.03% of their portfolio | 793.8k $109.5m | Added +21.5k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.29% of their portfolio | 790.2k $109.0m | Added +69.6k |
| LORD, ABBETT & CO. LLC 0.18% of their portfolio | 782.5k $107.9m | Added +688.5k |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 775.7k $107.0m | Added +84.1k |
| Polar Capital Holdings Plc 0.56% of their portfolio | 775.6k $107.0m | Reduced -60.3k |
| BRAIDWELL LP 3.25% of their portfolio | 730.2k $100.7m | Added +15.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 725.2k $100.0m | Added +38.3k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 715.1k $98.6m | Reduced -92.2k |
| EAGLE ASSET MANAGEMENT INC 0.51% of their portfolio | 713.5k $100.9m | Reduced -14.8k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.44% of their portfolio | 712.8k $98.3m | Reduced -40.1k |
| Vestal Point Capital, LP 8.10% of their portfolio | 710.0k $97.9m | Reduced -90.0k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 1.66% of their portfolio | 691.0k $95.3m | Reduced -205.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio | 599.4k $82.7m | Reduced -18.0k |
| California Public Employees Retirement System 0.06% of their portfolio | 580.6k $80.1m | Reduced -6.3k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 566.7k $78.2m | Added +93.7k |
| Avidity Partners Management LP 2.63% of their portfolio | 536.5k $74.0m | Reduced -121.5k |
| GW&K Investment Management, LLC 0.64% of their portfolio | 527.9k $72.8m | Reduced -8.1k |
| FIRST TRUST ADVISORS LP 0.07% of their portfolio | 526.6k $72.6m | Reduced -64.1k |
| Fiera Capital Corp 0.21% of their portfolio | 511.5k $70.6m | Reduced -5.3k |
| Allspring Global Investments Holdings, LLC 0.11% of their portfolio | 506.7k $69.9m | Added +96.6k |
| IEQ CAPITAL, LLC 1.00% of their portfolio | 506.1k $69.8m | Added +23.3k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.36% of their portfolio | 503.2k $69.4m | Reduced -91.2k |
| MILLENNIUM MANAGEMENT LLC 0.05% of their portfolio | 455.2k $62.8m | Reduced -233.7k |
| BNP PARIBAS FINANCIAL MARKETS 0.07% of their portfolio | 432.0k $59.6m | Added +124.4k |
| NORGES BANK 0.01% of their portfolio | 425.2k $58.6m | Added +154.0k |
| ORBIMED ADVISORS LLC 1.07% of their portfolio | 423.1k $58.4m | Reduced -96.2k |
| PRINCIPAL FINANCIAL GROUP INC 0.03% of their portfolio | 418.7k $57.7m | Added +430 |
| AMERIPRISE FINANCIAL INC 0.02% of their portfolio | 405.3k $55.9m | Reduced -20.4k |
| Legal & General Group Plc 0.02% of their portfolio | 402.6k $55.5m | Reduced -38.9k |
| PRIMECAP MANAGEMENT CO/CA/ 0.04% of their portfolio | 399.4k $55.1m | Added +1.1k |
| APG Asset Management N.V. 0.08% of their portfolio | 377.1k $48.2m | Reduced -5.4k |
| Amundi 0.02% of their portfolio | 361.7k $47.9m | Added +21.5k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 359.9k $49.6m | Added +22.8k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 357.2k $49.3m | Reduced -3.3k |
| Russell Investments Group, Ltd. 0.08% of their portfolio | 349.3k $48.2m | Reduced -56.0k |
| Sarissa Capital Management LP 8.36% of their portfolio | 346.4k $47.8m | Reduced -123.6k |
| JENNISON ASSOCIATES LLC 0.03% of their portfolio | 345.4k $47.6m | Reduced -106.0k |
| Clearbridge Investments, LLC 0.04% of their portfolio | 340.8k $47.0m | Unchanged |
| Assenagon Asset Management S.A. 0.12% of their portfolio | 337.7k $46.6m | Added +22.2k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 325.0k $44.8m | Reduced -11.5k |
| RHUMBLINE ADVISERS 0.04% of their portfolio | 322.1k $44.4m | Added +3.2k |
| Candriam S.C.A. 0.28% of their portfolio | 315.7k $43.5m | Reduced -54.2k |
| Robeco Institutional Asset Management B.V. 0.09% of their portfolio | 310.2k $42.8m | Added +132.5k |
| Swiss National Bank 0.03% of their portfolio | 294.2k $40.6m | Reduced -11.1k |
| Man Group plc 0.11% of their portfolio | 289.8k $40.0m | Reduced -28.7k |
| MACQUARIE GROUP LTD 0.04% of their portfolio | 276.0k $38.1m | Reduced -52.1k |
| PANAGORA ASSET MANAGEMENT INC 0.19% of their portfolio | 267.6k $36.9m | Added +197.2k |
| BARCLAYS PLC 0.02% of their portfolio | 257.2k $35.5m | Added +25.1k |
| LOOMIS SAYLES & CO L P 0.05% of their portfolio | 254.9k $35.2m | Reduced -936 |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 252.6k $34.8m | Added +8.6k |
| JANE STREET GROUP, LLC 0.04% of their portfolio | 252.0k $34.8m | Added +238.1k |
| Qube Research & Technologies Ltd 0.06% of their portfolio | 251.8k $34.7m | Added +82.2k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.12% of their portfolio | 245.4k $33.8m | Reduced -673.0k |
| AXA S.A. 0.10% of their portfolio | 243.7k $33.6m | Added +11.3k |
| UBS Group AG 0.01% of their portfolio | 235.6k $32.5m | Added +91.7k |
| FMR LLC 0.00% of their portfolio | 232.5k $32.1m | Reduced -32.0k |
| Hood River Capital Management LLC 0.70% of their portfolio | 228.0k $31.4m | Added +15.6k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 227.0k $31.3m | Reduced -555.0k |
| WELLS FARGO & COMPANY/MN 0.01% of their portfolio | 221.8k $30.6m | Added +118.8k |
| Iron Triangle Partners LP 3.14% of their portfolio | 220.0k $30.3m | New |
| JUPITER ASSET MANAGEMENT LTD 0.29% of their portfolio | 218.5k $30.1m | Added +8.4k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio | 206.4k $28.5m | Reduced -8.0k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 199.4k $27.5m | Reduced -189 |
| TWO SIGMA ADVISERS, LP 0.06% of their portfolio | 195.3k $26.9m | Reduced -15.2k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.03% of their portfolio | 188.5k $26.0m | Added +122.6k |
| TOBAM 2.20% of their portfolio | 178.3k $24.6m | Reduced -48.6k |
| National Pension Service 0.03% of their portfolio | 174.3k $24.0m | Added +174.2k |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 169.2k $23.3m | Reduced -31.0k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 160.2k $22.1m | Reduced -13.4k |
| SOROS FUND MANAGEMENT LLC 0.51% of their portfolio | 159.8k $22.0m | Reduced -25.2k |
| TWO SIGMA INVESTMENTS, LP 0.05% of their portfolio | 157.8k $21.8m | Reduced -67.1k |
| CITIGROUP INC 0.02% of their portfolio | 155.1k $21.4m | Reduced -16.9k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 154.7k $21.3m | Added +82.1k |
| Birchview Capital, LP 8.69% of their portfolio | 154.5k $21.3m | Unchanged |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 151.9k $20.9m | Reduced -23.9k |
| Caisse de depot et placement du Quebec 0.05% of their portfolio | 151.7k $20.9m | Added +76.9k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.02% of their portfolio | 150.1k $20.7m | Added +74.6k |