NEUROCRINE BIOSCIENCES INC NBIX
COM · Common Stock · CUSIP 64125C109 · ISIN US64125C1099
American biopharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Founded1992
- Websiteneurocrine.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($39.5m this quarter). Holder counts are more reliable. Shares outstanding: 97.7m as of 2023-07-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $94.61. Options: 10 managers hold calls ($51.6m notional), 9 hold puts ($37.7m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 466 |
| Q4 2022 | 530 |
| Q1 2023 | 488 |
| Q2 2023 | 457 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 282 | 209 |
| Q1 2023 | 253 | 249 |
| Q2 2023 | 199 | 257 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $35.1m | $27.4m | 0.78 |
| Q4 2022 | $36.4m | $3.9m | 0.11 |
| Q1 2023 | $17.5m | $30.2m | 1.72 |
| Q2 2023 | $51.6m | $37.7m | 0.73 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +831.9k |
| Balyasny Asset Management L.P. | New | +775.1k |
| Woodline Partners LP | Added | +753.5k |
| Man Group plc | New | +630.7k |
| IEQ CAPITAL, LLC | New | +481.3k |
| EAGLE ASSET MANAGEMENT INC | Added | +448.6k |
| Polar Capital Holdings Plc | New | +375.0k |
| MILLENNIUM MANAGEMENT LLC | Added | +282.0k |
| AMERICAN CENTURY COMPANIES INC | Added | +242.4k |
| Sarissa Capital Management LP | New | +231.3k |
Biggest sellers
| CONGRESS ASSET MANAGEMENT CO | Reduced | -914.3k |
| NORGES BANK | Reduced | -741.1k |
| Man Group plc | Sold out | -639.3k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Reduced | -535.0k |
| ENVESTNET ASSET MANAGEMENT INC | Reduced | -324.6k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -303.7k |
| BLAIR WILLIAM & CO/IL | Reduced | -297.5k |
| DSM CAPITAL PARTNERS LLC | Reduced | -199.3k |
| JPMORGAN CHASE & CO | Reduced | -194.1k |
| Caisse de depot et placement du Quebec | Reduced | -173.8k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $13.6m143.8k shares |
| JANE STREET GROUP, LLC | Added | $12.1m128.3k shares |
| CITIGROUP INC | Added | $5.7m60.0k shares |
| Balyasny Asset Management L.P. | New | $4.7m50.0k shares |
| Caption Management, LLC | Added | $4.2m45.0k shares |
| J. Goldman & Co LP | New | $3.7m39.4k shares |
| GROUP ONE TRADING LLC | Added | $3.0m31.3k shares |
| CITADEL ADVISORS LLC | Added | $2.6m28.0k shares |
| SIMPLEX TRADING, LLC | Added | $2.0m21.7k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| Iron Triangle Partners LP | New | $18.5m196.0k shares |
| CITIGROUP INC | Added | $5.7m60.0k shares |
| JANE STREET GROUP, LLC | Reduced | $3.4m36.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $3.1m32.6k shares |
| Caption Management, LLC | Unchanged | $2.8m30.0k shares |
| CITADEL ADVISORS LLC | Added | $2.8m29.4k shares |
| SIMPLEX TRADING, LLC | Added | $1.1m11.8k shares |
| GROUP ONE TRADING LLC | Reduced | $367.8k3.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-28 | 12.1% |
| DODGE & COX 13G · institution new · filed 2025-05-14 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
| JPMORGAN CHASE & CO 13G · institution -1.1 pts · filed 2026-10-15 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 4 | $1.6m | — |
| Q1 2022 | 0 | — | 10 | $7.8m | — |
| Q2 2022 | 0 | — | 4 | $3.6m | — |
| Q3 2022 | 0 | — | 2 | $2.5m | — |
| Q4 2022 | 0 | — | 6 | $20.4m | — |
| Q1 2023 | 0 | — | 12 | $21.0m | — |
| Q2 2023 | 0 | — | 3 | $3.8m | $3.8m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-05-01 | Cooke Julie Chief Human Resources Officer | Sold plan | $1.2m11.4k shares |
| 2023-05-01 | RASTETTER WILLIAM H Director | Sold plan | $436.1k4.3k shares |
| 2023-04-25 | Cooke Julie Chief Human Resources Officer | Sold plan | $10.4k100 shares |
| 2023-04-24 | ROBERTS EIRY Chief Medical Officer | Sold plan | $1.5m14.4k shares |
| 2023-04-21 | RASTETTER WILLIAM H Director | Sold plan | $633.8k6.0k shares |
| 2023-04-19 | RASTETTER WILLIAM H Director | Sold plan | $94.8k903 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.04% of their portfolio | 13.5m $1.3bn | Added +15.5k |
| VANGUARD GROUP INC 0.02% of their portfolio | 9.6m $902.5m | Reduced -26.8k |
| STATE STREET CORP 0.02% of their portfolio | 4.0m $373.1m | Added +156.6k |
| Bellevue Group AG 3.51% of their portfolio | 2.6m $246.4m | Reduced -500 |
| JPMORGAN CHASE & CO 0.02% of their portfolio | 2.0m $185.0m | Reduced -194.1k |
| JANUS HENDERSON GROUP PLC 0.11% of their portfolio | 1.9m $180.0m | Reduced -85.7k |
| MORGAN STANLEY 0.02% of their portfolio | 1.9m $176.2m | Added +213.1k |
| ARMISTICE CAPITAL, LLC 3.91% of their portfolio | 1.6m $155.6m | Added +58.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.22% of their portfolio | 1.6m $155.0m | Reduced -303.7k |
| Bank of New York Mellon Corp 0.03% of their portfolio | 1.6m $149.9m | Reduced -62.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.5m $143.4m | Added +87.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio | 1.4m $132.0m | Added +228.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 1.3m $125.4m | Reduced -64.3k |
| CITADEL ADVISORS LLC 0.14% of their portfolio | 1.3m $123.2m | Added +831.9k |
| Rock Springs Capital Management LP 2.87% of their portfolio | 1.3m $120.7m | Added +69.4k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 2.44% of their portfolio | 1.2m $114.1m | Reduced -535.0k |
| Amundi 0.06% of their portfolio | 1.2m $112.4m | Reduced -31.8k |
| Woodline Partners LP 1.29% of their portfolio | 1.2m $108.7m | Added +753.5k |
| AMERICAN CENTURY COMPANIES INC 0.08% of their portfolio | 1.1m $104.1m | Added +242.4k |
| BROWN ADVISORY INC 0.16% of their portfolio | 1.1m $103.7m | Added +21.0k |
| DSM CAPITAL PARTNERS LLC 1.62% of their portfolio | 1.1m $100.0m | Reduced -199.3k |
| BRAIDWELL LP 2.88% of their portfolio | 933.4k $88.0m | Added +166.6k |
| PICTET ASSET MANAGEMENT SA 0.10% of their portfolio | 924.4k $87.2m | Added +200.2k |
| MILLENNIUM MANAGEMENT LLC 0.08% of their portfolio | 850.3k $80.2m | Added +282.0k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 848.2k $80.0m | Reduced -27.4k |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 824.6k $77.8m | Reduced -145.2k |
| Balyasny Asset Management L.P. 0.20% of their portfolio | 775.1k $73.1m | New |
| FRANKLIN RESOURCES INC 0.03% of their portfolio | 728.2k $68.7m | Added +17.8k |
| EAGLE ASSET MANAGEMENT INC 0.38% of their portfolio | 726.8k $68.5m | Added +448.6k |
| Avidity Partners Management LP 2.19% of their portfolio | 665.3k $62.7m | Reduced -150.4k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.19% of their portfolio | 657.0k $62.0m | Added +44.4k |
| Man Group plc 0.18% of their portfolio | 630.7k $59.5m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 604.9k $57.0m | Added +20.5k |
| California Public Employees Retirement System 0.05% of their portfolio | 587.2k $55.4m | Reduced -16.5k |
| GW&K Investment Management, LLC 0.51% of their portfolio | 574.0k $54.1m | Reduced -6.8k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio | 568.9k $57.6m | Unchanged |
| Invesco Ltd. 0.01% of their portfolio | 562.4k $53.0m | Reduced -13.9k |
| TWO SIGMA ADVISERS, LP 0.13% of their portfolio | 554.3k $52.3m | Reduced -124.5k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.21% of their portfolio | 550.6k $51.9m | Reduced -84.2k |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 530.9k $50.1m | Reduced -143.1k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 500.2k $47.2m | Reduced -45.6k |
| ORBIMED ADVISORS LLC 0.84% of their portfolio | 489.0k $46.1m | Unchanged |
| IEQ CAPITAL, LLC 0.92% of their portfolio | 481.3k $45.4m | New |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 479.7k $45.2m | Reduced -69.8k |
| Legal & General Group Plc 0.01% of their portfolio | 457.7k $43.2m | Reduced -36.2k |
| Candriam S.C.A. 0.30% of their portfolio | 440.4k $41.5m | Added +23.2k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.24% of their portfolio | 435.5k $41.1m | Added +4.1k |
| Russell Investments Group, Ltd. 0.07% of their portfolio | 400.4k $37.8m | Added +57.6k |
| PRIMECAP MANAGEMENT CO/CA/ 0.03% of their portfolio | 393.4k $37.1m | Added +21.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 383.9k $36.2m | Reduced -3.6k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.22% of their portfolio | 375.3k $35.4m | Added +120.7k |
| Polar Capital Holdings Plc 0.24% of their portfolio | 375.0k $35.4m | New |
| Allspring Global Investments Holdings, LLC 0.06% of their portfolio | 369.6k $34.9m | Added +31.6k |
| Fiera Capital Corp 0.10% of their portfolio | 358.0k $33.8m | Reduced -11.4k |
| AQR CAPITAL MANAGEMENT LLC 0.07% of their portfolio | 357.7k $33.7m | Added +126.6k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 357.5k $33.7m | Added +17.3k |
| Swiss National Bank 0.02% of their portfolio | 352.2k $33.2m | Reduced -28.3k |
| SCOUT INVESTMENTS, INC. 0.72% of their portfolio | 351.9k $35.3m | Added +221.6k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 336.2k $31.7m | Added +15.7k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 328.3k $31.0m | Added +21.7k |
| JUPITER ASSET MANAGEMENT LTD 0.34% of their portfolio | 327.8k $30.9m | Added +17.9k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 324.2k $30.6m | Added +80.4k |
| APG Asset Management N.V. 0.05% of their portfolio | 314.5k $27.2m | Reduced -12.3k |
| Clearbridge Investments, LLC 0.03% of their portfolio | 312.0k $29.4m | Added +61.2k |
| TOBAM 2.22% of their portfolio | 311.7k $29.4m | Reduced -50.7k |
| Logos Global Management LP 3.91% of their portfolio | 300.0k $28.3m | Added +100.0k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 282.2k $27.7m | Added +215.0k |
| Assenagon Asset Management S.A. 0.10% of their portfolio | 265.0k $25.0m | Added +174.5k |
| MACQUARIE GROUP LTD 0.03% of their portfolio | 259.4k $24.5m | Reduced -33.2k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 242.5k $22.9m | Reduced -42.4k |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 240.5k $22.7m | Reduced -24.9k |
| D. E. Shaw & Co., Inc. 0.04% of their portfolio | 240.5k $22.7m | Added +61.4k |
| TWO SIGMA INVESTMENTS, LP 0.06% of their portfolio | 237.8k $22.4m | Reduced -132.3k |
| Sarissa Capital Management LP 2.17% of their portfolio | 231.3k $21.8m | New |
| Qube Research & Technologies Ltd 0.08% of their portfolio | 228.5k $21.5m | Reduced -73.8k |
| BNP PARIBAS FINANCIAL MARKETS 0.04% of their portfolio | 220.5k $20.8m | Reduced -21.2k |
| JENNISON ASSOCIATES LLC 0.02% of their portfolio | 220.1k $20.8m | Reduced -6.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio | 213.3k $20.1m | Added +8.8k |
| Hood River Capital Management LLC 0.60% of their portfolio | 213.1k $20.1m | Added +7.0k |
| CITIGROUP INC 0.03% of their portfolio | 209.1k $19.7m | Reduced -9.7k |
| LOOMIS SAYLES & CO L P 0.03% of their portfolio | 207.1k $19.5m | Added +44.1k |
| Impax Asset Management Group plc 0.08% of their portfolio | 200.0k $18.9m | Unchanged |
| BARCLAYS PLC 0.01% of their portfolio | 194.5k $18.3m | Reduced -53.5k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 176.0k $16.6m | Added +7.7k |
| Federation des caisses Desjardins du Quebec 0.16% of their portfolio | 174.4k $16.4m | Added +164.9k |
| VOYA INVESTMENT MANAGEMENT LLC 0.02% of their portfolio | 170.8k $16.1m | Added +5.3k |
| Prosight Management, LP 4.69% of their portfolio | 170.0k $16.0m | Added +90.0k |
| Caisse de depot et placement du Quebec 0.04% of their portfolio | 168.7k $15.9m | Reduced -173.8k |
| Connor, Clark & Lunn Investment Management Ltd. 0.08% of their portfolio | 162.3k $15.3m | Reduced -78.9k |
| Robeco Institutional Asset Management B.V. 0.04% of their portfolio | 155.2k $14.6m | Reduced -7.3k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 152.7k $14.4m | Reduced -4.7k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.09% of their portfolio | 148.1k $14.0m | Reduced -1.4k |
| VIRGINIA RETIREMENT SYSTEMS ET Al 0.13% of their portfolio | 144.0k $13.6m | Reduced -36.3k |
| Parkman Healthcare Partners LLC 2.28% of their portfolio | 139.7k $13.2m | Reduced -78.1k |
| BANCO BILBAO VIZCAYA ARGENTARIA, S.A. 0.17% of their portfolio | 138.8k $13.1m | Added +5.0k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 138.1k $13.0m | Reduced -13.3k |
| RICE HALL JAMES & ASSOCIATES, LLC 0.72% of their portfolio | 135.1k $12.7m | Reduced -2.2k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.22% of their portfolio | 135.0k $12.7m | Unchanged |
| Driehaus Capital Management LLC 0.15% of their portfolio | 127.4k $12.0m | Reduced -64.9k |
| Skandinaviska Enskilda Banken AB (publ) 0.08% of their portfolio | 126.3k $11.9m | Reduced -58.4k |