NEUROCRINE BIOSCIENCES INC NBIX
COM · Common Stock · CUSIP 64125C109 · ISIN US64125C1099
American biopharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Founded1992
- Websiteneurocrine.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($47.2m this quarter). Holder counts are more reliable. Shares outstanding: 96.6m as of 2023-01-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $119.33. Options: 10 managers hold calls ($36.4m notional), 5 hold puts ($3.9m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 466 |
| Q4 2022 | 530 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $35.1m | $27.4m | 0.78 |
| Q4 2022 | $36.4m | $3.9m | 0.11 |
Biggest buyers
| MORGAN STANLEY | Added | +1.5m |
| BlackRock Inc. | Added | +580.5k |
| Invesco Ltd. | Added | +521.6k |
| FMR LLC | Added | +443.9k |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +436.6k |
| VANGUARD GROUP INC | Added | +339.3k |
| Woodline Partners LP | New | +308.4k |
| EAGLE ASSET MANAGEMENT INC | New | +278.5k |
| DEUTSCHE BANK AG\ | Added | +269.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +267.3k |
Biggest sellers
| JANUS HENDERSON GROUP PLC | Reduced | -7.4m |
| T. Rowe Price Investment Management, Inc. | Sold out | -1.0m |
| ARMISTICE CAPITAL, LLC | Reduced | -424.0k |
| FRANKLIN RESOURCES INC | Reduced | -358.5k |
| Iron Triangle Partners LP | Reduced | -255.5k |
| AMERICAN CENTURY COMPANIES INC | Reduced | -238.0k |
| ORBIMED ADVISORS LLC | Reduced | -208.8k |
| JPMORGAN CHASE & CO | Reduced | -201.2k |
| Tri Locum Partners LP | Sold out | -196.4k |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Reduced | -187.5k |
Biggest calls
| GROUP ONE TRADING LLC | Added | $11.9m99.7k shares |
| JANE STREET GROUP, LLC | Reduced | $8.2m68.4k shares |
| CITADEL ADVISORS LLC | Added | $5.7m47.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $4.3m35.6k shares |
| SIMPLEX TRADING, LLC | Added | $3.0m25.5k shares |
| Caption Management, LLC | Reduced | $3.0m25.0k shares |
| Walleye Trading LLC | New | $262.8k2.2k shares |
| Cutler Group LLC / CA | New | $33.0k4.9k shares |
| SG Americas Securities, LLC | New | $21.0k20.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| Caption Management, LLC | New | $2.4m20.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $656.9k5.5k shares |
| CITADEL ADVISORS LLC | Added | $609.1k5.1k shares |
| JANE STREET GROUP, LLC | Reduced | $238.9k2.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-28 | 12.1% |
| DODGE & COX 13G · institution new · filed 2025-05-14 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.2% |
| JPMORGAN CHASE & CO 13G · institution -1.1 pts · filed 2026-10-15 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 4 | $1.6m | — |
| Q1 2022 | 0 | — | 10 | $7.8m | — |
| Q2 2022 | 0 | — | 4 | $3.6m | — |
| Q3 2022 | 0 | — | 2 | $2.5m | — |
| Q4 2022 | 0 | — | 6 | $20.4m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-11-30 | BENEVICH ERIC Chief Commercial Officer | Sold | $6.3m50.0k shares |
| 2022-11-29 | Onyia Jude Chief Scientific Officer | Sold | $284.1k2.3k shares |
| 2022-11-10 | BENEVICH ERIC Chief Commercial Officer | Sold | $12.5k100 shares |
| 2022-11-08 | BENEVICH ERIC Chief Commercial Officer | Sold | $3.1m24.6k shares |
| 2022-11-08 | Cooke Julie Chief Human Resources Officer | Sold | $698.9k5.6k shares |
| 2022-11-08 | Lippoldt Darin Chief Legal Officer | Sold | $635.5k5.1k shares |
| 2022-11-03 | BENEVICH ERIC Chief Commercial Officer | Sold | $1.1m9.0k shares |
| 2022-11-03 | Cooke Julie Chief Human Resources Officer | Sold | $908.0k7.3k shares |
| 2022-11-03 | Lippoldt Darin Chief Legal Officer | Sold | $564.8k4.5k shares |
| 2022-11-02 | Cooke Julie Chief Human Resources Officer | Sold | $143.0k1.1k shares |
| 2022-11-02 | BENEVICH ERIC Chief Commercial Officer | Sold | $50.0k400 shares |
| 2022-11-02 | Lippoldt Darin Chief Legal Officer | Sold | $50.0k400 shares |
| 2022-11-01 | Lippoldt Darin Chief Legal Officer | Sold | $1.2m10.0k shares |
| 2022-10-31 | LYONS GARY A Director | Sold | $1.7m15.0k shares |
| 2022-10-31 | Boyer David W. Chief Corp. Affairs Officer | Sold | $147.8k1.3k shares |
| 2022-10-27 | Lippoldt Darin Chief Legal Officer | Sold | $566.3k4.9k shares |
| 2022-10-26 | Lippoldt Darin Chief Legal Officer | Sold | $584.0k5.1k shares |
| 2022-10-17 | BENEVICH ERIC Chief Commercial Officer | Sold | $549.7k5.0k shares |
| 2022-10-04 | Lippoldt Darin Chief Legal Officer | Sold | $1.1m10.0k shares |
| 2022-10-04 | LYONS GARY A Director | Sold | $552.7k5.0k shares |
| 2022-10-03 | Boyer David W. Chief Corp. Affairs Officer | Sold | $153.2k1.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.05% of their portfolio | 12.6m $1.5bn | Added +580.5k |
| VANGUARD GROUP INC 0.03% of their portfolio | 9.3m $1.1bn | Added +339.3k |
| STATE STREET CORP 0.03% of their portfolio | 3.7m $445.5m | Reduced -36.5k |
| Bellevue Group AG 4.40% of their portfolio | 2.8m $331.2m | Reduced -81.9k |
| JANUS HENDERSON GROUP PLC 0.21% of their portfolio | 2.4m $288.5m | Reduced -7.4m |
| JPMORGAN CHASE & CO 0.04% of their portfolio | 2.2m $259.2m | Reduced -201.2k |
| MORGAN STANLEY 0.03% of their portfolio | 2.0m $244.6m | Added +1.5m |
| Avidity Partners Management LP 4.97% of their portfolio | 1.8m $212.6m | Reduced -75.7k |
| Bank of New York Mellon Corp 0.05% of their portfolio | 1.7m $201.2m | Reduced -56.2k |
| RENAISSANCE TECHNOLOGIES LLC 0.26% of their portfolio | 1.6m $192.7m | Added +171.2k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 3.74% of their portfolio | 1.5m $180.7m | Unchanged |
| Invesco Ltd. 0.05% of their portfolio | 1.4m $170.5m | Added +521.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.03% of their portfolio | 1.4m $170.2m | Reduced -38.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.4m $165.7m | Added +71.0k |
| DSM CAPITAL PARTNERS LLC 2.65% of their portfolio | 1.3m $159.2m | Added +10.5k |
| GOLDMAN SACHS GROUP INC 0.05% of their portfolio | 1.3m $158.8m | Added +127.9k |
| WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio | 1.2m $144.1m | Added +436.6k |
| Rock Springs Capital Management LP 3.23% of their portfolio | 1.1m $134.1m | Unchanged |
| BROWN ADVISORY INC 0.24% of their portfolio | 1.1m $126.8m | Reduced -13.3k |
| NORGES BANK 0.03% of their portfolio | 935.9k $111.8m | Added +62.2k |
| Amundi 0.06% of their portfolio | 923.4k $102.0m | Added +106.6k |
| CONGRESS ASSET MANAGEMENT CO 1.10% of their portfolio | 917.8k $109.6m | Reduced -176.4k |
| ARMISTICE CAPITAL, LLC 2.89% of their portfolio | 900.0k $107.5m | Reduced -424.0k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 861.5k $102.9m | Added +3.4k |
| MILLENNIUM MANAGEMENT LLC 0.11% of their portfolio | 840.3k $100.4m | Added +267.3k |
| AMERICAN CENTURY COMPANIES INC 0.08% of their portfolio | 805.5k $96.2m | Reduced -238.0k |
| FMR LLC 0.01% of their portfolio | 786.5k $93.9m | Added +443.9k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.44% of their portfolio | 763.7k $91.2m | Reduced -28.3k |
| TWO SIGMA ADVISERS, LP 0.24% of their portfolio | 722.7k $86.3m | Added +127.7k |
| FRANKLIN RESOURCES INC 0.04% of their portfolio | 693.8k $82.9m | Reduced -358.5k |
| 1832 Asset Management L.P. 0.17% of their portfolio | 691.4k $82.6m | Added +216.5k |
| ORBIMED ADVISORS LLC 1.57% of their portfolio | 687.7k $82.1m | Reduced -208.8k |
| DEUTSCHE BANK AG\ 0.05% of their portfolio | 685.5k $81.9m | Added +269.1k |
| FIRST TRUST ADVISORS LP 0.10% of their portfolio | 673.7k $80.5m | Reduced -91.0k |
| California Public Employees Retirement System 0.06% of their portfolio | 631.5k $75.4m | Reduced -18.2k |
| AMERIPRISE FINANCIAL INC 0.02% of their portfolio | 603.6k $72.1m | Reduced -125.3k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 599.3k $71.6m | Reduced -111.1k |
| PICTET ASSET MANAGEMENT SA 0.10% of their portfolio | 581.5k $69.5m | Reduced -70.4k |
| GW&K Investment Management, LLC 0.70% of their portfolio | 574.5k $68.6m | Reduced -20.8k |
| TWO SIGMA INVESTMENTS, LP 0.22% of their portfolio | 571.0k $68.2m | Added +202.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 566.0k $67.6m | Added +25.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.24% of their portfolio | 551.4k $65.9m | Added +17.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio | 542.6k $64.8m | Added +28.6k |
| Allspring Global Investments Holdings, LLC 0.10% of their portfolio | 496.2k $59.3m | Reduced -42.8k |
| Legal & General Group Plc 0.02% of their portfolio | 491.2k $58.7m | Reduced -5.8k |
| PRINCIPAL FINANCIAL GROUP INC 0.04% of their portfolio | 400.7k $47.9m | Added +11.7k |
| Swiss National Bank 0.03% of their portfolio | 388.7k $46.4m | Reduced -25.5k |
| Fiera Capital Corp 0.14% of their portfolio | 372.5k $44.5m | Reduced -2.6k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 343.5k $41.0m | Reduced -14.0k |
| Man Group plc 0.14% of their portfolio | 316.0k $37.7m | Added +210.3k |
| APG Asset Management N.V. 0.07% of their portfolio | 311.3k $37.2m | Added +77.0k |
| Woodline Partners LP 0.51% of their portfolio | 308.4k $36.8m | New |
| RHUMBLINE ADVISERS 0.05% of their portfolio | 300.0k $35.8m | Added +12.5k |
| TOBAM 2.28% of their portfolio | 287.8k $34.4m | Added +969 |
| MACQUARIE GROUP LTD 0.04% of their portfolio | 285.3k $34.1m | Reduced -990 |
| Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio | 284.1k $33.9m | Reduced -179 |
| Fairmount Funds Management LLC 5.36% of their portfolio | 283.0k $33.8m | Unchanged |
| EAGLE ASSET MANAGEMENT INC 0.20% of their portfolio | 278.5k $33.4m | New |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.25% of their portfolio | 272.7k $32.6m | Reduced -187.5k |
| Candriam S.C.A. 0.22% of their portfolio | 269.2k $32.1m | Reduced -2.3k |
| D. E. Shaw & Co., Inc. 0.05% of their portfolio | 259.0k $30.9m | Added +119.8k |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.68% of their portfolio | 251.1k $30.0m | Added +160.5k |
| Allianz Asset Management GmbH 0.07% of their portfolio | 250.9k $30.0m | Added +73.6k |
| Clearbridge Investments, LLC 0.03% of their portfolio | 250.8k $30.0m | Unchanged |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 247.8k $29.6m | Reduced -32 |
| Driehaus Capital Management LLC 0.43% of their portfolio | 241.3k $28.8m | Added +18.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio | 230.2k $27.5m | Reduced -43.8k |
| Qube Research & Technologies Ltd 0.16% of their portfolio | 222.8k $26.6m | Added +214.7k |
| JENNISON ASSOCIATES LLC 0.03% of their portfolio | 219.4k $26.2m | Added +78.1k |
| UBS Group AG 0.01% of their portfolio | 216.8k $25.9m | Added +64.7k |
| Assenagon Asset Management S.A. 0.10% of their portfolio | 208.4k $24.9m | Added +123.6k |
| CREDIT SUISSE AG/ 0.03% of their portfolio | 206.9k $24.7m | Reduced -104 |
| FRED ALGER MANAGEMENT, LLC 0.13% of their portfolio | 206.7k $24.7m | Added +206.5k |
| Cubist Systematic Strategies, LLC 0.20% of their portfolio | 199.8k $23.9m | Added +44.2k |
| Hood River Capital Management LLC 0.87% of their portfolio | 199.7k $23.9m | Added +5.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.06% of their portfolio | 198.5k $23.7m | Added +68.5k |
| Robeco Institutional Asset Management B.V. 0.06% of their portfolio | 188.2k $22.5m | Added +123.8k |
| CITADEL ADVISORS LLC 0.03% of their portfolio | 185.6k $22.2m | Reduced -50.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 181.0k $21.6m | Added +574 |
| VIRGINIA RETIREMENT SYSTEMS ET Al 0.22% of their portfolio | 176.8k $21.1m | Reduced -6.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.12% of their portfolio | 176.6k $21.1m | Reduced -20.7k |
| Impax Asset Management Group plc 0.09% of their portfolio | 175.0k $20.9m | Added +25.0k |
| Polar Capital Holdings Plc 0.17% of their portfolio | 173.9k $20.8m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 166.9k $19.9m | Added +11.7k |
| VOYA INVESTMENT MANAGEMENT LLC 0.02% of their portfolio | 161.8k $19.3m | Added +36.8k |
| SCOUT INVESTMENTS, INC. 0.39% of their portfolio | 159.1k $19.0m | Reduced -73.8k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio | 158.0k $18.9m | Added +2.5k |
| Russell Investments Group, Ltd. 0.04% of their portfolio | 156.4k $18.7m | Added +34.0k |
| BARCLAYS PLC 0.02% of their portfolio | 155.8k $18.6m | First filing |
| Skandinaviska Enskilda Banken AB (publ) 0.14% of their portfolio | 155.1k $18.5m | Reduced -1.7k |
| MARSICO CAPITAL MANAGEMENT LLC 0.94% of their portfolio | 151.9k $18.1m | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.13% of their portfolio | 150.2k $17.9m | Reduced -1.2k |
| RICE HALL JAMES & ASSOCIATES, LLC 1.02% of their portfolio | 149.4k $17.8m | Reduced -3.6k |
| BANK OF NOVA SCOTIA 0.04% of their portfolio | 140.3k $16.8m | Reduced -115.0k |
| CITIGROUP INC 0.02% of their portfolio | 138.0k $16.5m | Added +2.4k |
| Lombard Odier Asset Management (Switzerland) SA 1.31% of their portfolio | 137.4k $16.4m | Reduced -61.6k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.32% of their portfolio | 135.0k $16.1m | Reduced -100.0k |
| BANCO BILBAO VIZCAYA ARGENTARIA, S.A. 0.23% of their portfolio | 133.7k $16.0m | Unchanged |
| Retirement Systems of Alabama 0.07% of their portfolio | 126.7k $15.1m | Added +1.5k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 123.5k $14.7m | Reduced -856 |