NAUTILUS BIOTECHNOLOGY INC NAUT
COM · Common Stock · CUSIP 63909J108
- SectorTechnology
- IndustryLaboratory Analytical Instruments
- HeadquartersSeattle, WA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $1.87. Options: 3 managers hold calls ($38.3k notional), 3 hold puts ($92.2k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 86 |
| Q4 2022 | 82 |
| Q1 2023 | 74 |
| Q2 2023 | 76 |
| Q3 2023 | 76 |
| Q4 2023 | 77 |
| Q1 2024 | 74 |
| Q2 2024 | 79 |
| Q3 2024 | 84 |
| Q4 2024 | 89 |
| Q1 2025 | 89 |
| Q2 2025 | 72 |
| Q3 2025 | 68 |
| Q4 2025 | 68 |
| Q1 2026 | 81 |
| Q2 2026 | 93 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 30 | 14 |
| Q4 2024 | 41 | 28 |
| Q1 2025 | 32 | 41 |
| Q2 2025 | 36 | 45 |
| Q3 2025 | 17 | 40 |
| Q4 2025 | 30 | 21 |
| Q1 2026 | 37 | 26 |
| Q2 2026 | 59 | 28 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $5.1k | $975 | 0.19 |
| Q1 2026 | $261.1k | $388 | 0.00 |
| Q2 2026 | $38.3k | $92.2k | 2.40 |
Biggest buyers
| BlackRock, Inc. | Added | +2.5m |
| CITADEL ADVISORS LLC | New | +1.9m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | +890.9k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +662.0k |
| BARCLAYS PLC | Added | +652.0k |
| JPMORGAN CHASE & CO | New | +614.2k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +424.8k |
| STATE STREET CORP | Added | +343.2k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +337.7k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +314.2k |
Biggest sellers
| a16z Capital Management, L.L.C. | Reduced | -8.6m |
| AMAZON COM INC | Sold out | -1.5m |
| Clearstead Advisors, LLC | Reduced | -1.4m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.1m |
| PERCEPTIVE ADVISORS LLC | Reduced | -960.0k |
| Tikvah Management LLC | Sold out | -726.9k |
| GOLDMAN SACHS GROUP INC | Reduced | -138.0k |
| JANE STREET GROUP, LLC | Sold out | -61.8k |
| Brevan Howard Capital Management LP | Sold out | -60.5k |
| MARSHALL WACE, LLP | Reduced | -54.3k |
Biggest calls
| CITADEL ADVISORS LLC | New | $35.2k18.8k shares |
| SIMPLEX TRADING, LLC | Reduced | $3.0k1.6k shares |
| GROUP ONE TRADING LLC | Unchanged | $187100 shares |
Biggest puts
| GROUP ONE TRADING LLC | New | $49.2k26.3k shares |
| CITADEL ADVISORS LLC | New | $37.0k19.8k shares |
| SIMPLEX TRADING, LLC | Added | $6.0k3.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Mallick Parag 13D · may seek influence +0.2 pts · filed 2026-03-04 | 17.6% |
| Patel Sujal M 13D · may seek influence +0.6 pts · filed 2026-03-04 | 16.3% |
| PERCEPTIVE ADVISORS LLC 13D · may seek influence -1.0 pts · filed 2026-08-14 | 9.1% |
Fell to 5% or below in the last year: AH Bio Fund II, L.P. (4.9%, 2026-09-11)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 1 | $76.7k | 0 | — | — |
| Q2 2025 | 2 | $21.4k | 0 | — | — |
| Q3 2025 | 2 | $147.6k | 0 | — | — |
| Q4 2025 | 1 | $6.0k | 0 | — | — |
| Q1 2026 | 1 | $65.2k | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-06-02 | Andreessen Marc L +5 10% owner · By AH Bio Fund II, L.P. | Sold | $10.8m4.6m shares |
| 2026-06-02 | Andreessen Marc L +5 10% owner · By Andreessen Horowitz LSV Fund II, L.P. | Sold | $902.5k384.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| PERCEPTIVE ADVISORS LLC 0.34% of their portfolio | 11.6m $21.8m | Reduced -960.0k |
| a16z Capital Management, L.L.C. 0.12% of their portfolio | 9.1m $16.9m | Reduced -8.6m |
| Cercano Management LLC 1.79% of their portfolio | 7.2m $13.4m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 2.7m $5.0m | Added +2.5m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.5m $4.8m | Added +4.4k |
| Comprehensive Financial Management LLC 0.14% of their portfolio | 2.2m $4.1m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.9m $3.5m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $2.4m | Added +662.0k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 1.1m $2.0m | Added +314.2k |
| Clearstead Advisors, LLC 0.02% of their portfolio | 892.8k $1.7m | Reduced -1.4m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 890.9k $1.7m | New |
| SENTINEL TRUST CO LBA 0.12% of their portfolio | 750.0k $1.4m | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 725.3k $1.4m | Added +652.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 690.5k $1.3m | Added +424.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 614.2k $1.1m | New |
| STATE STREET CORP 0.00% of their portfolio | 559.5k $1.0m | Added +343.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 475.8k $889.3k | Added +146.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 381.2k $712.9k | Added +274.2k |
| HRT FINANCIAL LP 0.00% of their portfolio | 361.1k $675.0k | Added +295.8k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 353.1k $660.3k | Added +47.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 337.7k $631.6k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 265.6k $496.6k | Reduced -54.3k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 257.3k $481.2k | Added +177.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 252.8k $472.6k | Reduced -138.0k |
| HILLMAN CO 0.13% of their portfolio | 200.0k $374.0k | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 188.7k $352.9k | Reduced -1.1m |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 180.0k $336.6k | Added +50.0k |
| Corient Private Wealth LP 0.00% of their portfolio | 164.8k $308.2k | Added +50.0k |
| Crewe Advisors LLC 0.02% of their portfolio | 136.1k $254.4k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 123.7k $231.3k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 122.6k $229.2k | New |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 101.1k $189.0k | Added +46.4k |
| MORGAN STANLEY 0.00% of their portfolio | 98.2k $183.7k | Added +48.7k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 77.1k $144.1k | Added +13.9k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 67.9k $127.0k | Reduced -15.1k |
| Palumbo Wealth Management LLC 0.03% of their portfolio | 66.2k $123.9k | Added +1.0k |
| Nuveen, LLC 0.00% of their portfolio | 66.2k $123.8k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 58.6k $109.5k | New |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 58.2k $108.7k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 52.7k $98.5k | New |
| CITIZENS FINANCIAL GROUP INC/RI 0.00% of their portfolio | 50.0k $93.5k | Unchanged |
| Virtu Financial LLC 0.00% of their portfolio | 49.9k $93.0k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 49.4k $91.2k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 48.5k $90.7k | New |
| Caprock Group, LLC 0.00% of their portfolio | 47.1k $88.1k | Added +3.0k |
| Fayez Sarofim & Co 0.00% of their portfolio | 45.0k $84.2k | Unchanged |
| Ashton Thomas Private Wealth, LLC 0.00% of their portfolio | 45.0k $84.2k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 42.3k $79.0k | Added +42.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 40.8k $77.0k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 38.6k $72.3k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 36.6k $68.4k | New |
| Invesco Ltd. 0.00% of their portfolio | 35.2k $65.8k | New |
| Presidio Capital Management, LLC 0.02% of their portfolio | 34.7k $64.8k | Unchanged |
| AXQ CAPITAL, LP 0.01% of their portfolio | 34.1k $63.9k | New |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 34.0k $63.6k | Reduced -3 |
| Squarepoint Ops LLC 0.00% of their portfolio | 33.7k $63.1k | New |
| Badgley Phelps Wealth Managers, LLC 0.00% of their portfolio | 30.0k $56.1k | Unchanged |
| Catalyst Funds Management Pty Ltd 0.00% of their portfolio | 26.3k $49.3k | Reduced -20.0k |
| Callan Family Office, LLC 0.00% of their portfolio | 26.0k $48.6k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 23.1k $43.1k | Added +1.9k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 22.9k $42.8k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 19.0k $35.5k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 18.0k $33.6k | Added +4.1k |
| UBS Group AG 0.00% of their portfolio | 17.1k $32.0k | Reduced -9.8k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 16.6k $31.1k | Unchanged |
| TD Waterhouse Canada Inc. 0.00% of their portfolio | 16.0k $29.3k | Added +15.0k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 14.0k $26.2k | New |
| FNY Investment Advisers, LLC 0.01% of their portfolio | 14.0k $26.0k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 13.2k $24.7k | New |
| Vanguard Capital Wealth Advisors 0.02% of their portfolio | 13.0k $24.3k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 11.9k $22.2k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 11.5k $21.5k | Reduced -1.9k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 11.2k $21.0k | Added +11.1k |
| Garde Capital, Inc. 0.00% of their portfolio | 11.0k $20.6k | Unchanged |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 10.0k $18.7k | Reduced -5.0k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 9.4k $17.6k | Added +3.2k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 8.2k $15.3k | New |
| BFSG, LLC 0.00% of their portfolio | 6.7k $12.5k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 4.8k $9.1k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.5k $8.4k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 4.0k $7.4k | New |
| FMR LLC 0.00% of their portfolio | 3.6k $6.7k | Added +240 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 3.1k $5.8k | Added +2.8k |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 3.0k $5.6k | Added +2.0k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.8k $5.3k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 1.1k $2.0k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 922 $1.7k | New |
| GILL CAPITAL PARTNERS, LLC 0.00% of their portfolio | 250 $468 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 119 $223 | Added +118 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 100 $187 | Unchanged |
| Allworth Financial LP 0.00% of their portfolio | 72 $135 | New |
| Optiver Holding B.V. 0.00% of their portfolio | 40 $75 | Unchanged |
| Covestor Ltd 0.00% of their portfolio | 8 $0 | Unchanged |