MIRUM PHARMACEUTICALS INC MIRM
COM · Common Stock · CUSIP 604749101 · ISIN US6047491013
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersFoster City, CA
- Founded2018
- Websitemirumpharma.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($431.4k this quarter). Holder counts are more reliable. Shares outstanding: 46.6m as of 2023-10-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $31.59. Options: 6 managers hold calls ($2.0m notional), 7 hold puts ($2.3m).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 112 |
| Q4 2022 | 105 |
| Q1 2023 | 119 |
| Q2 2023 | 148 |
| Q3 2023 | 161 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 61 | 49 |
| Q1 2023 | 64 | 40 |
| Q2 2023 | 95 | 37 |
| Q3 2023 | 99 | 48 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $422.2k | $137.5k | 0.33 |
| Q1 2023 | $10.3m | $84.1k | 0.01 |
| Q2 2023 | $486.2k | $1.3m | 2.74 |
| Q3 2023 | $2.0m | $2.3m | 1.15 |
Biggest buyers
| BVF INC/IL | New | +4.4m |
| Frazier Life Sciences Management, L.P. | Added | +2.1m |
| JANUS HENDERSON GROUP PLC | Added | +1.7m |
| Avidity Partners Management LP | New | +1.1m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +665.0k |
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +499.4k |
| BOONE CAPITAL MANAGEMENT LLC | New | +389.8k |
| Nuveen Asset Management, LLC | Added | +357.2k |
| TWO SIGMA ADVISERS, LP | Added | +328.3k |
| CITADEL ADVISORS LLC | Added | +287.4k |
Biggest sellers
| RiverVest Venture Management LLC | Sold out | -1.6m |
| Point72 Asset Management, L.P. | Sold out | -601.0k |
| Prosight Management, LP | Reduced | -321.5k |
| WASATCH ADVISORS LP | Sold out | -230.5k |
| NOVO HOLDINGS A/S | Reduced | -184.2k |
| JANE STREET GROUP, LLC | Reduced | -182.0k |
| UBS Group AG | Reduced | -110.5k |
| DEUTSCHE BANK AG\ | Reduced | -97.0k |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | Reduced | -81.9k |
| Soleus Capital Management, L.P. | Reduced | -73.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $1.1m36.0k shares |
| JANE STREET GROUP, LLC | New | $322.3k10.2k shares |
| SIMPLEX TRADING, LLC | Added | $274.0k8.7k shares |
| CITADEL ADVISORS LLC | Reduced | $227.5k7.2k shares |
| GROUP ONE TRADING LLC | Reduced | $41.1k1.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| WOLVERINE ASSET MANAGEMENT LLC | Unchanged | $660.4k20.9k shares |
| JANE STREET GROUP, LLC | Added | $625.7k19.8k shares |
| J. Goldman & Co LP | New | $426.6k13.5k shares |
| CITADEL ADVISORS LLC | Reduced | $293.9k9.3k shares |
| SIMPLEX TRADING, LLC | Added | $246.0k7.8k shares |
| GROUP ONE TRADING LLC | New | $41.1k1.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Janus Henderson Group Ltd. 13G · institution -2.1 pts · filed 2026-08-13 | 9.7% |
Frazier Life Sciences IX, L.P.
13D · may seek influence
-0.8 pts · filed 2026-01-27
Stated purposeItem 4 is hereby amended and restated in its entirety to read as follows: Each of FLS IX, FLS X, FLSPF, FLS XI and FLS XII acquired the FLS IX Shares, the FLS X Shares, the FLSPF Shares, the FLS XI Shares and the FLS XII Shares, as the case may be, for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, FLS IX, FLS X, FLSPF, FLS XI and FLS XII and the other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporat… Full filing |
6.8% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 6.2% |
| BlackRock, Inc. 13G · institution filed 2026-04-27 | 5.7% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), EVENTIDE ASSET MANAGEMENT, LLC (4.1%, 2026-02-13)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2021 | 2 | $121.3k | 6 | $145.8k | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 1 | $6.0m | — |
| Q1 2023 | 0 | — | 4 | $155.5k | — |
| Q2 2023 | 0 | — | 1 | $832.7k | $832.7k |
| Q3 2023 | 2 | $4.5m | 6 | $785.0k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-09-14 | GREY MICHAEL G Director | Sold | $454.9k14.2k shares |
| 2023-09-13 | Heron Patrick J Director · By Frazier Life Sciences X, L.P. | Bought | $81.4k2.6k shares |
| 2023-09-13 | GREY MICHAEL G Director | Sold | $12.5k392 shares |
| 2023-09-12 | Heron Patrick J Director · By Frazier Life Sciences X, L.P. | Bought | $114.8k3.8k shares |
| 2023-09-11 | BJERKHOLT ERIC Chief Financial Officer | Bought | $296.5k10.0k shares |
| 2023-09-11 | Heron Patrick J Director · By Frazier Life Sciences X, L.P. | Bought | $142.0k4.7k shares |
| 2023-08-31 | Heron Patrick J Director · By Frazier Life Sciences X, L.P. | Bought | $3.9m148.0k shares |
| 2023-08-25 | Howe Jolanda SVP, Global Controller | Sold | $90.7k3.5k shares |
| 2023-07-03 | Peetz Christopher President and CEO, director | Sold | $141.0k5.5k shares |
| 2023-07-03 | Vig Pamela Head of Research & Development | Sold | $36.6k1.4k shares |
| 2023-07-03 | Radovich Peter Chief Operating Officer | Sold | $36.6k1.4k shares |
| 2023-07-03 | Longpre Lara Chief Development Officer | Sold | $25.8k1.0k shares |
| 2023-07-03 | Howe Jolanda SVP, Global Controller | Sold | $23.5k915 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| Frazier Life Sciences Management, L.P. 13.59% of their portfolio | 6.5m $204.5m | Added +2.1m |
| BVF INC/IL 3.72% of their portfolio | 4.4m $138.1m | New |
| EVENTIDE ASSET MANAGEMENT, LLC 2.25% of their portfolio | 4.0m $125.1m | Added +499.4k |
| NEA Management Company, LLC 5.34% of their portfolio | 2.2m $69.1m | Unchanged |
| BlackRock Inc. 0.00% of their portfolio | 2.1m $66.8m | Added +83.0k |
| JANUS HENDERSON GROUP PLC 0.04% of their portfolio | 1.9m $60.8m | Added +1.7m |
| Rock Springs Capital Management LP 1.54% of their portfolio | 1.8m $57.5m | Unchanged |
| CITADEL ADVISORS LLC 0.06% of their portfolio | 1.7m $53.7m | Added +287.4k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.7m $53.5m | Added +98.7k |
| STATE STREET CORP 0.00% of their portfolio | 1.6m $51.2m | Added +126.5k |
| NOVO HOLDINGS A/S 3.50% of their portfolio | 1.5m $47.4m | Reduced -184.2k |
| CADIAN CAPITAL MANAGEMENT, LP 1.83% of their portfolio | 1.4m $45.3m | Added +170.0k |
| Nicholas Investment Partners, LP 2.83% of their portfolio | 1.2m $37.9m | Added +284.2k |
| Polar Capital Holdings Plc 0.28% of their portfolio | 1.2m $37.1m | Added +250.0k |
| Avidity Partners Management LP 1.45% of their portfolio | 1.1m $36.1m | New |
| TANG CAPITAL MANAGEMENT LLC 5.07% of their portfolio | 1.1m $35.9m | Unchanged |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 744.6k $23.5m | Added +133.5k |
| Pictet Asset Management Holding SA 0.03% of their portfolio | 739.0k $23.4m | First filing |
| PERCEPTIVE ADVISORS LLC 0.71% of their portfolio | 672.0k $21.2m | Added +70.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio | 665.0k $21.0m | New |
| AXA S.A. 0.07% of their portfolio | 617.1k $19.5m | Reduced -51.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 575.1k $18.2m | Added +49.5k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.06% of their portfolio | 533.7k $16.9m | Added +196.3k |
| Woodline Partners LP 0.17% of their portfolio | 452.7k $14.3m | Added +124.9k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 432.8k $13.7m | Added +357.2k |
| TWO SIGMA ADVISERS, LP 0.03% of their portfolio | 390.9k $12.4m | Added +328.3k |
| BOONE CAPITAL MANAGEMENT LLC 3.89% of their portfolio | 389.8k $12.3m | New |
| Prosight Management, LP 3.54% of their portfolio | 353.5k $11.2m | Reduced -321.5k |
| TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio | 328.8k $10.4m | Added +225.7k |
| BARCLAYS PLC 0.01% of their portfolio | 299.1k $9.5m | Added +12.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 275.2k $8.7m | Added +1.4k |
| Penn Capital Management Company, LLC 0.80% of their portfolio | 246.0k $7.8m | Added +6.7k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.04% of their portfolio | 244.0k $7.7m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 240.8k $7.6m | Reduced -34.1k |
| Erste Asset Management GmbH 0.12% of their portfolio | 225.0k $7.1m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 224.6k $7.1m | Added +152.3k |
| Ensign Peak Advisors, Inc 0.02% of their portfolio | 222.6k $7.0m | Reduced -3.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 221.9k $7.0m | Added +12.7k |
| BAKER BROS. ADVISORS LP 0.03% of their portfolio | 190.5k $6.0m | New |
| Invesco Ltd. 0.00% of their portfolio | 163.8k $5.2m | Added +128.4k |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.04% of their portfolio | 152.4k $4.8m | Reduced -81.9k |
| MORGAN STANLEY 0.00% of their portfolio | 146.9k $4.6m | Added +42.4k |
| Rafferty Asset Management, LLC 0.03% of their portfolio | 137.2k $4.3m | Added +21.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 136.4k $4.3m | New |
| Highlander Partners, L.P. 3.84% of their portfolio | 123.0k $3.9m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 122.6k $3.9m | Added +37.9k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 118.1k $3.7m | Added +5.9k |
| SPHERA FUNDS MANAGEMENT LTD. 0.87% of their portfolio | 114.3k $3.6m | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.02% of their portfolio | 114.1k $3.6m | Added +76.4k |
| SILVERARC CAPITAL MANAGEMENT, LLC 1.30% of their portfolio | 110.1k $3.5m | Added +3.7k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 106.2k $3.4m | Added +38.6k |
| Soleus Capital Management, L.P. 0.33% of their portfolio | 103.0k $3.3m | Reduced -73.0k |
| ARDSLEY ADVISORY PARTNERS LP 0.86% of their portfolio | 100.0k $3.2m | New |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 100.0k $3.2m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 99.8k $3.2m | Added +61.3k |
| Squarepoint Ops LLC 0.02% of their portfolio | 99.7k $3.1m | Added +62.4k |
| Cubist Systematic Strategies, LLC 0.04% of their portfolio | 98.1k $3.1m | Added +94.1k |
| Jump Financial, LLC 0.10% of their portfolio | 87.4k $2.8m | Added +75.0k |
| Simplify Asset Management Inc. 0.36% of their portfolio | 70.0k $2.2m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 68.7k $2.2m | Added +57.1k |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 0.72% of their portfolio | 67.5k $2.1m | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 65.6k $2.1m | Reduced -182.0k |
| Parkman Healthcare Partners LLC 0.38% of their portfolio | 65.0k $2.1m | Added +2.6k |
| Palo Alto Investors LP 0.19% of their portfolio | 64.7k $2.0m | Unchanged |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% of their portfolio | 61.0k $1.9m | Added +37.0k |
| CITIGROUP INC 0.00% of their portfolio | 58.7k $1.9m | Added +17.9k |
| Knights of Columbus Asset Advisors LLC 0.17% of their portfolio | 57.9k $1.8m | Added +817 |
| Swiss National Bank 0.00% of their portfolio | 54.4k $1.7m | Added +700 |
| RICE HALL JAMES & ASSOCIATES, LLC 0.11% of their portfolio | 53.4k $1.7m | Reduced -1.1k |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 49.9k $1.6m | Added +11.9k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 42.4k $1.3m | Added +494 |
| Secure Asset Management, LLC 0.38% of their portfolio | 39.7k $1.3m | Added +4.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 38.8k $1.2m | Added +3.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 38.8k $1.2m | Added +16.0k |
| Values First Advisors, Inc. 0.77% of their portfolio | 37.9k $1.2m | New |
| Legato Capital Management LLC 0.17% of their portfolio | 36.3k $1.1m | Added +10.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 36.1k $1.1m | Added +1.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 32.9k $1.0m | Added +16.0k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 32.3k $1.0m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 32.0k $1.0m | Reduced -67.7k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 30.4k $960.5k | Added +13.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 30.2k $954.9k | Reduced -541 |
| Steward Partners Investment Advisory, LLC 0.01% of their portfolio | 30.1k $949.6k | Added +21.1k |
| Affinity Asset Advisors, LLC 0.31% of their portfolio | 30.0k $948.0k | Unchanged |
| HRT FINANCIAL LP 0.01% of their portfolio | 29.1k $919.0k | New |
| Campbell & CO Investment Adviser LLC 0.11% of their portfolio | 28.6k $902.4k | Added +13.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 27.3k $863.1k | Reduced -3.3k |
| Lion Point Capital, LP 0.78% of their portfolio | 27.0k $853.2k | Unchanged |
| Hennion & Walsh Asset Management, Inc. 0.05% of their portfolio | 26.5k $837.2k | Added +12.5k |
| SG Americas Securities, LLC 0.01% of their portfolio | 25.7k $814.0k | Added +9.1k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 23.3k $737.0k | New |
| PROFUND ADVISORS LLC 0.04% of their portfolio | 23.1k $728.6k | Added +1.9k |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 23.0k $727.8k | Reduced -19.1k |
| Legal & General Group Plc 0.00% of their portfolio | 22.6k $715.6k | Added +1.8k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 22.5k $710.3k | Reduced -6.5k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 21.8k $688.8k | Reduced -16.0k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 20.5k $649.2k | Added +8.5k |
| Verition Fund Management LLC 0.01% of their portfolio | 19.4k $613.0k | New |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 19.1k $603.7k | Added +7.2k |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 18.9k $598.0k | Added +950 |