Vault-13

MIRATI THERAPEUTICS INC MRTX

COM · Common Stock · CUSIP 60468T105 · ISIN US60468T1051

218 institutional holders +3 vs Q3 2023
85,531,20085.5m shares reported held*
$5.0bnreported value*
62 new 58 added 69 reduced 61 sold out net bought ≈ $267.6m (+4.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $58.76. Options: 22 managers hold calls ($87.7m notional), 22 hold puts ($103.4m).

Trends to Q4 2023

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 244Q4 22: 233Q1 23: 223Q2 23: 208Q3 23: 215Q4 23: 218218Q3 22Q4 22Q1 23Q2 23Q3 23Q4 23
Numbers
QuarterHolders
Q3 2022244
Q4 2022233
Q1 2023223
Q2 2023208
Q3 2023215
Q4 2023218

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 133 bought or addedQ4 22: 118 cut or sold outQ4 22Q1 23: 119 bought or addedQ1 23: 104 cut or sold outQ1 23Q2 23: 106 bought or addedQ2 23: 108 cut or sold outQ2 23Q3 23: 137 bought or addedQ3 23: 88 cut or sold outQ3 23Q4 23: 120 bought or addedQ4 23: 130 cut or sold outQ4 23
Numbers
QuarterBought or addedCut or sold out
Q4 2022133118
Q1 2023119104
Q2 2023106108
Q3 202313788
Q4 2023120130

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150mQ1 23 calls: $16.7mQ1 23 puts: $10.6mQ1 23P/C 0.64Q2 23 calls: $33.6mQ2 23 puts: $11.3mQ2 23P/C 0.34Q3 23 calls: $75.7mQ3 23 puts: $23.3mQ3 23P/C 0.31Q4 23 calls: $87.7mQ4 23 puts: $103.4mQ4 23P/C 1.18
Numbers
QuarterCallsPutsP/C
Q1 2023$16.7m$10.6m0.64
Q2 2023$33.6m$11.3m0.34
Q3 2023$75.7m$23.3m0.31
Q4 2023$87.7m$103.4m1.18

Biggest buyers

MORGAN STANLEY Added +9,876,632+9.9m
Simplicity Solutions, LLC New +3,135,973+3.1m
BAKER BROS. ADVISORS LP Added +2,711,656+2.7m
ALPINE ASSOCIATES MANAGEMENT INC. New +1,881,400+1.9m
EcoR1 Capital, LLC Added +1,648,580+1.6m
Sio Capital Management, LLC New +1,451,925+1.5m
TANG CAPITAL MANAGEMENT LLC Added +1,378,059+1.4m
MANGROVE PARTNERS IM, LLC New +1,101,736+1.1m
FARALLON CAPITAL MANAGEMENT, L.L.C. Added +1,023,472+1.0m
Pentwater Capital Management LP New +902,632+902.6k

Biggest sellers

WELLINGTON MANAGEMENT GROUP LLP Sold out -3,319,922-3.3m
PRICE T ROWE ASSOCIATES INC /MD/ Reduced -2,394,968-2.4m
Artal Group S.A. Sold out -2,024,226-2.0m
ORBIMED ADVISORS LLC Sold out -1,959,050-2.0m
Assenagon Asset Management S.A. Sold out -1,825,678-1.8m
Avoro Capital Advisors LLC Reduced -1,779,826-1.8m
FMR LLC Reduced -1,523,588-1.5m
Camber Capital Management LP Sold out -1,500,000-1.5m
CITADEL ADVISORS LLC Reduced -1,064,827-1.1m
Fiera Capital Corp Sold out -1,038,836-1.0m

Biggest calls

Artal Group S.A. Reduced $29.4m500.0k shares
BANK OF AMERICA CORP /DE/ New $9.5m162.0k shares
SILVERARC CAPITAL MANAGEMENT, LLC Unchanged $8.8m150.0k shares
JANE STREET GROUP, LLC Reduced $7.7m130.4k shares
SIMPLEX TRADING, LLC Unchanged $6.5m111.0k shares
Caption Management, LLC Added $6.1m104.1k shares
GROUP ONE TRADING LLC Added $6.1m103.5k shares
Jefferies Financial Group Inc. Added $3.7m63.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $2.4m40.0k shares
GTS SECURITIES LLC Added $1.4m24.3k shares

Biggest puts

GROUP ONE TRADING LLC Added $31.9m543.3k shares
CSS LLC/IL New $26.6m452.7k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $15.1m256.4k shares
UBS Group AG Added $7.1m120.5k shares
SIMPLEX TRADING, LLC Added $4.6m78.7k shares
JANE STREET GROUP, LLC Added $3.6m61.2k shares
Maven Securities LTD New $3.2m55.0k shares
CITADEL ADVISORS LLC Reduced $2.5m42.3k shares
EQUITEC PROPRIETARY MARKETS, LLC New $2.1m34.9k shares
Jefferies Financial Group Inc. Reduced $1.7m29.2k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q4 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 MORGAN STANLEY 0.03% of their portfolio NEW YORK, NY 12,338,76412.3m $724.9m $724.9m 0.03% Added +9.9m +9,876,632
2 EcoR1 Capital, LLC 11.28% of their portfolio San Francisco, CA 7,396,9797.4m $434.6m $434.6m 11.28% Added +1.6m +1,648,580
3 RTW INVESTMENTS, LP 6.21% of their portfolio NEW YORK, NY 6,768,5146.8m $397.7m $397.7m 6.21% Unchanged
4 VANGUARD GROUP INC 0.01% of their portfolio Valley Forge, PA 5,306,6935.3m $311.8m $311.8m 0.01% Reduced -392.9k -392,939
5 Avoro Capital Advisors LLC 3.97% of their portfolio NEW YORK, NY 4,886,8404.9m $287.1m $287.1m 3.97% Reduced -1.8m -1,779,826
6 BAKER BROS. ADVISORS LP 2.76% of their portfolio NEW YORK, NY 4,121,4404.1m $242.1m $242.1m 2.76% Added +2.7m +2,711,656
7 BlackRock Inc. 0.01% of their portfolio New York, NY 3,866,2023.9m $227.1m $227.1m 0.01% Added +321.9k +321,891
8 Boxer Capital, LLC 9.37% of their portfolio San Diego, CA 3,201,4403.2m $188.1m $188.1m 9.37% Unchanged
9 Simplicity Solutions, LLC 5.03% of their portfolio MINNEAPOLIS, MN 3,135,9733.1m $184.2m $184.2m 5.03% New
10 Braslyn Ltd. 98.96% of their portfolio NEW PROVIDENCE, C5 3,135,9663.1m $184.2m $184.2m 98.96% First filing
11 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 2,324,2682.3m $136.6m $136.6m 0.01% Reduced -421.7k -421,700
12 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.74% of their portfolio SAN FRANCISCO, CA 2,024,4722.0m $118.9m $118.9m 0.74% Added +1.0m +1,023,472
13 ALPINE ASSOCIATES MANAGEMENT INC. 5.67% of their portfolio PALM BEACH, FL 1,881,4001.9m $110.5m $110.5m 5.67% New
14 TANG CAPITAL MANAGEMENT LLC 8.46% of their portfolio SAN DIEGO, CA 1,558,0591.6m $91.5m $91.5m 8.46% Added +1.4m +1,378,059
15 Paradigm Biocapital Advisors LP 4.25% of their portfolio NEW YORK, NY 1,543,1161.5m $90.7m $90.7m 4.25% Reduced -125.0k -125,000
16 Sio Capital Management, LLC 21.96% of their portfolio NEW YORK, NY 1,451,9251.5m $85.3m $85.3m 21.96% New
17 MANGROVE PARTNERS IM, LLC 4.56% of their portfolio Greenwich, CT 1,101,7361.1m $64.7m $64.7m 4.56% New
18 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 1,010,0991.0m $59.3m $59.3m 0.01% Added +817.4k +817,394
19 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 980,029980.0k $57.6m $57.6m 0.01% Added +98.8k +98,803
20 Pentwater Capital Management LP 1.00% of their portfolio Naples, FL 902,632902.6k $53.0m $53.0m 1.00% New
21 Rock Springs Capital Management LP 1.21% of their portfolio Baltimore, MD 835,776835.8k $49.1m $49.1m 1.21% Reduced -295.4k -295,431
22 Magnetar Financial LLC 1.25% of their portfolio EVANSTON, IL 834,390834.4k $49.0m $49.0m 1.25% New
23 HSBC HOLDINGS PLC 0.04% of their portfolio LONDON, X0 783,092783.1k $46.0m $46.0m 0.04% New
24 NORGES BANK 0.01% of their portfolio OSLO, Q8 751,604751.6k $44.2m $44.2m 0.01% Added +319.7k +319,661
25 ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio NASHVILLE, TN 738,486738.5k $43.4m $43.4m 0.02% Added +618.9k +618,858
26 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.08% of their portfolio Boston, MA 667,424667.4k $39.2m $39.2m 0.08% Reduced -507.6k -507,576
27 BANK OF MONTREAL /CAN/ 0.01% of their portfolio TORONTO, A6 651,314651.3k $38.4m $38.4m 0.01% New
28 ARMISTICE CAPITAL, LLC 0.78% of their portfolio NEW YORK, NY 500,000500.0k $29.4m $29.4m 0.78% Reduced -864.1k -864,098
29 BARCLAYS PLC 0.01% of their portfolio LONDON, X0 492,345492.3k $28.9m $28.9m 0.01% Added +364.6k +364,571
30 NATIONAL BANK OF CANADA /FI/ 0.05% of their portfolio MONTREAL, A8 473,500473.5k $28.0m $28.0m 0.05% New
31 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 422,059422.1k $24.8m $24.8m 0.01% Reduced -229.7k -229,663
32 Madison Avenue Partners, LP 3.46% of their portfolio NEW YORK, NY 417,427417.4k $24.5m $24.5m 3.46% New
33 GROUP ONE TRADING LLC 0.76% of their portfolio CHICAGO, IL 414,114414.1k $24.3m $24.3m 0.76% Added +375.4k +375,408
34 JANE STREET GROUP, LLC 0.03% of their portfolio NEW YORK, NY 409,843409.8k $24.1m $24.1m 0.03% Added +222.9k +222,917
35 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.08% of their portfolio TORONTO, A6 381,200381.2k $22.4m $22.4m 0.08% New
36 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 365,428365.4k $21.5m $21.5m 0.01% Added +22.0k +21,986
37 CSS LLC/IL 1.58% of their portfolio CHICAGO, IL 343,845343.8k $20.2m $20.2m 1.58% New
38 WATER ISLAND CAPITAL LLC 2.07% of their portfolio NEW YORK, NY 343,735343.7k $20.2m $20.2m 2.07% New
39 Nuveen Asset Management, LLC 0.01% of their portfolio CHICAGO, IL 294,396294.4k $17.3m $17.3m 0.01% Added +16.0k +15,955
40 Calamos Advisors LLC 0.08% of their portfolio NAPERVILLE, IL 277,808277.8k $16.3m $16.3m 0.08% New
41 New York Life Investment Management LLC 0.15% of their portfolio New York, NY 255,584255.6k $15.0m $15.0m 0.15% New
42 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 253,930253.9k $14.9m $14.9m 0.00% Added +13.2k +13,150
43 GABELLI FUNDS LLC 0.11% of their portfolio Rye, NY 241,587241.6k $14.2m $14.2m 0.11% New
44 Sand Grove Capital Management LLP 4.09% of their portfolio LONDON, X0 224,632224.6k $13.2m $13.2m 4.09% New
45 GABELLI & Co INVESTMENT ADVISERS, INC. 2.42% of their portfolio Rye, NY 219,513219.5k $12.9m $12.9m 2.42% New
46 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 216,814216.8k $12.7m $12.7m 0.00% Added +146.9k +146,935
47 NATIXIS 0.10% of their portfolio PARIS, I0 215,731215.7k $12.7m $12.7m 0.10% New
48 5AM Venture Management, LLC 3.00% of their portfolio SAN FRANCISCO, CA 192,500192.5k $11.3m $11.3m 3.00% Unchanged
49 TUDOR INVESTMENT CORP ET AL 0.14% of their portfolio STAMFORD, CT 171,537171.5k $10.1m $10.1m 0.14% New
50 Rafferty Asset Management, LLC 0.04% of their portfolio New York, NY 158,931158.9k $9.3m $9.3m 0.04% Reduced -90.7k -90,681
51 Susquehanna Portfolio Strategies, LLC 0.16% of their portfolio Bala Cynwyd, PA 154,720154.7k $9.1m $9.1m 0.16% First filing
52 SYQUANT CAPITAL SAS 40.81% of their portfolio PARIS, I0 153,920153.9k $9.0m $9.0m 40.81% New
53 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio BALA CYNWYD, PA 145,890145.9k $8.6m $8.6m 0.01% Reduced -137.5k -137,501
54 COWEN AND COMPANY, LLC 0.48% of their portfolio NEW YORK, NY 123,783123.8k $7.3m $7.3m 0.48% New
55 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 115,976116.0k $6.8m $6.8m 0.00% Reduced -126.6k -126,585
56 ADAR1 Capital Management, LLC 2.84% of their portfolio AUSTIN, TX 108,000108.0k $6.3m $6.3m 2.84% First filing
57 Affinity Asset Advisors, LLC 1.17% of their portfolio NEW YORK, NY 100,049100.0k $5.9m $5.9m 1.17% Added +39.6k +39,623
58 Westchester Capital Management, LLC 0.21% of their portfolio VALHALLA, NY 90,63890.6k $5.3m $5.3m 0.21% New
59 DAFNA Capital Management LLC 1.26% of their portfolio LOS ANGELES, CA 89,38789.4k $5.3m $5.3m 1.26% Reduced -3.5k -3,500
60 Swiss National Bank 0.00% of their portfolio ZURICH, V8 83,00083.0k $4.9m $4.9m 0.00% Reduced -28.8k -28,800
61 Frazier Life Sciences Management, L.P. 0.25% of their portfolio PALO ALTO, CA 80,00080.0k $4.7m $4.7m 0.25% New
62 FIL Ltd 0.00% of their portfolio HAMILTON, D0 75,44675.4k $4.4m $4.4m 0.00% Added +6.1k +6,062
63 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 75,23375.2k $4.4m $4.4m 0.00% Added +40.2k +40,234
64 BANK OF NOVA SCOTIA 0.01% of their portfolio TORONTO, A6 72,00072.0k $4.2m $4.2m 0.01% New
65 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 66,61166.6k $3.9m $3.9m 0.00% Reduced -1.1m -1,064,827
66 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 65,65765.7k $3.9m $3.9m 0.00% Added +5.6k +5,589
67 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 65,53465.5k $3.9m $3.9m 0.00% Reduced -232.7k -232,660
68 Amundi 0.00% of their portfolio Paris, I0 64,87364.9k $3.8m $3.8m 0.00% Added +53.9k +53,915
69 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio TALLAHASSEE, FL 64,30364.3k $3.8m $3.8m 0.01% Added +1.7k +1,707
70 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 61,96162.0k $3.6m $3.6m 0.00% Reduced -95.7k -95,693
71 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 61,22061.2k $3.6m $3.6m 0.00% Added +9.3k +9,349
72 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 60,00060.0k $3.5m $3.5m 0.00% Unchanged
73 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 59,53359.5k $3.5m $3.5m 0.00% Reduced -485.1k -485,093
74 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 58,62658.6k $3.4m $3.4m 0.00% Added +24.2k +24,246
75 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 55,97756.0k $3.3m $3.3m 0.01% Added +1.2k +1,167
76 Maven Securities LTD 0.37% of their portfolio ST HELIER, Y9 55,00055.0k $3.2m $3.2m 0.37% Reduced -35.0k -35,000
77 UBS Group AG 0.00% of their portfolio ZURICH, V8 51,94551.9k $3.1m $3.1m 0.00% Added +18.9k +18,863
78 Clearline Capital LP 0.34% of their portfolio NEW YORK, NY 51,27551.3k $3.0m $3.0m 0.34% Unchanged
79 SIMPLEX TRADING, LLC 0.09% of their portfolio CHICAGO, IL 49,58549.6k $2.9m $2.9m 0.09% Reduced -6.8k -6,848
80 HRT FINANCIAL LP 0.02% of their portfolio NEW YORK, NY 49,52649.5k $2.9m $2.9m 0.02% New
81 GTS SECURITIES LLC 0.06% of their portfolio NEW YORK, NY 47,71647.7k $2.8m $2.8m 0.06% Added +1.1k +1,091
82 Verition Fund Management LLC 0.03% of their portfolio GREENWICH, CT 46,59946.6k $2.7m $2.7m 0.03% Reduced -159.9k -159,880
83 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 46,57646.6k $2.7m $2.7m 0.00% Reduced -8.6k -8,579
84 Polar Asset Management Partners Inc. 0.07% of their portfolio TORONTO, A6 45,00045.0k $2.6m $2.6m 0.07% New
85 Alberta Investment Management Corp 0.02% of their portfolio EDMONTON, A0 44,30044.3k $2.6m $2.6m 0.02% New
86 State of New Jersey Common Pension Fund D 0.01% of their portfolio TRENTON, NJ 44,02744.0k $2.6m $2.6m 0.01% Reduced -23.4k -23,369
87 Legal & General Group Plc 0.00% of their portfolio London, X0 43,04443.0k $2.5m $2.5m 0.00% Reduced -3.9k -3,941
88 Kellner Capital, LLC 4.38% of their portfolio NEW YORK, NY 41,40041.4k $2.4m $2.4m 4.38% New
89 First Trust Capital Management L.P. 0.19% of their portfolio CHICAGO, IL 41,23141.2k $2.4m $2.4m 0.19% New
90 PRELUDE CAPITAL MANAGEMENT, LLC 0.21% of their portfolio NEW YORK, NY 40,79940.8k $2.4m $2.4m 0.21% Added +36.0k +36,021
91 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 40,20040.2k $2.4m $2.4m 0.00% Reduced -277.4k -277,401
92 ING GROEP NV 0.02% of their portfolio AMSTERDAM, P7 40,00040.0k $2.4m $2.4m 0.02% New
93 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 38,06138.1k $2.2m $2.2m 0.00% Reduced -2.4m -2,394,968
94 Caption Management, LLC 0.23% of their portfolio OKLAHOMA CITY, OK 36,60036.6k $2.2m $2.2m 0.23% Reduced -14.4k -14,400
95 GAMCO INVESTORS, INC. ET AL 0.02% of their portfolio GREENWICH, CT 36,10036.1k $2.1m $2.1m 0.02% New
96 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 36,00036.0k $2.1m $2.1m 0.00% Reduced -352.2k -352,165
97 EQUITEC PROPRIETARY MARKETS, LLC 2.23% of their portfolio CHICAGO, IL 35,10035.1k $2.1m $2.1m 2.23% New
98 STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio MADISON, WI 33,50333.5k $2.0m $2.0m 0.01% Reduced -1.6k -1,601
99 GUGGENHEIM CAPITAL LLC 0.01% of their portfolio CHICAGO, IL 33,46233.5k $2.0m $2.0m 0.01% Added +2.6k +2,557
100 SG Americas Securities, LLC 0.02% of their portfolio NEW YORK, NY 32,40832.4k $1.9m $1.9m 0.02% Reduced -17.2k -17,170