Vault-13

MIRATI THERAPEUTICS INC MRTX

COM · Common Stock · CUSIP 60468T105 · ISIN US60468T1051

215 institutional holders +7 vs Q2 2023
80,960,90681.0m shares reported held*
$3.5bnreported value*
43 new 94 added 52 reduced 36 sold out net bought ≈ $619.7m (+14.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.4m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $43.57. Options: 18 managers hold calls ($75.7m notional), 12 hold puts ($23.3m).

Trends to Q3 2023

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 244Q4 22: 233Q1 23: 223Q2 23: 208Q3 23: 215215Q3 22Q4 22Q1 23Q2 23Q3 23
Numbers
QuarterHolders
Q3 2022244
Q4 2022233
Q1 2023223
Q2 2023208
Q3 2023215

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 133 bought or addedQ4 22: 118 cut or sold outQ4 22Q1 23: 119 bought or addedQ1 23: 104 cut or sold outQ1 23Q2 23: 106 bought or addedQ2 23: 108 cut or sold outQ2 23Q3 23: 137 bought or addedQ3 23: 88 cut or sold outQ3 23
Numbers
QuarterBought or addedCut or sold out
Q4 2022133118
Q1 2023119104
Q2 2023106108
Q3 202313788

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25m$50m$75m$100mQ4 22 calls: $86.2mQ4 22 puts: $34.1mQ4 22P/C 0.40Q1 23 calls: $16.7mQ1 23 puts: $10.6mQ1 23P/C 0.64Q2 23 calls: $33.6mQ2 23 puts: $11.3mQ2 23P/C 0.34Q3 23 calls: $75.7mQ3 23 puts: $23.3mQ3 23P/C 0.31
Numbers
QuarterCallsPutsP/C
Q4 2022$86.2m$34.1m0.40
Q1 2023$16.7m$10.6m0.64
Q2 2023$33.6m$11.3m0.34
Q3 2023$75.7m$23.3m0.31

Biggest buyers

EcoR1 Capital, LLC New +5,748,399+5.7m
RTW INVESTMENTS, LP Added +2,295,529+2.3m
FMR LLC Added +1,404,045+1.4m
Boxer Capital, LLC Added +1,201,440+1.2m
ADAGE CAPITAL PARTNERS GP, L.L.C. New +1,175,000+1.2m
Avoro Capital Advisors LLC Added +1,111,111+1.1m
ORBIMED ADVISORS LLC Added +1,045,400+1.0m
Assenagon Asset Management S.A. Added +1,016,858+1.0m
Balyasny Asset Management L.P. New +775,747+775.7k
VANGUARD GROUP INC Added +721,357+721.4k

Biggest sellers

ARMISTICE CAPITAL, LLC Reduced -2,613,902-2.6m
PERCEPTIVE ADVISORS LLC Sold out -719,103-719.1k
MILLENNIUM MANAGEMENT LLC Reduced -470,929-470.9k
MARSHALL WACE, LLP Reduced -437,179-437.2k
MORGAN STANLEY Reduced -382,340-382.3k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Reduced -379,428-379.4k
Camber Capital Management LP Reduced -300,000-300.0k
BRAIDWELL LP Sold out -240,625-240.6k
Allspring Global Investments Holdings, LLC Reduced -220,584-220.6k
JACOBS LEVY EQUITY MANAGEMENT, INC Sold out -195,320-195.3k

Biggest calls

Artal Group S.A. Added $30.5m700.0k shares
JANE STREET GROUP, LLC Added $11.6m265.8k shares
SILVERARC CAPITAL MANAGEMENT, LLC Unchanged $6.5m150.0k shares
SIMPLEX TRADING, LLC Reduced $4.8m111.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.6m105.3k shares
ORBIMED ADVISORS LLC New $4.4m100.0k shares
Caption Management, LLC New $3.6m82.1k shares
GROUP ONE TRADING LLC Reduced $3.3m75.4k shares
CITADEL ADVISORS LLC Added $1.9m42.8k shares
Jefferies Financial Group Inc. Added $1.4m31.8k shares

Biggest puts

UBS Group AG Added $5.2m120.4k shares
MOORE CAPITAL MANAGEMENT, LP New $4.4m100.0k shares
GROUP ONE TRADING LLC Reduced $3.1m71.6k shares
Jefferies Financial Group Inc. Added $2.6m59.6k shares
CITADEL ADVISORS LLC Reduced $2.4m54.7k shares
SIMPLEX TRADING, LLC Added $1.9m42.7k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.8m41.1k shares
GTS SECURITIES LLC New $753.6k17.3k shares
JANE STREET GROUP, LLC Added $605.5k13.9k shares
Caption Management, LLC Unchanged $557.6k12.8k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q3 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 RTW INVESTMENTS, LP 6.22% of their portfolio NEW YORK, NY 6,768,5146.8m $294.8m $294.8m 6.22% Added +2.3m +2,295,529
2 Avoro Capital Advisors LLC 4.53% of their portfolio NEW YORK, NY 6,666,6666.7m $290.4m $290.4m 4.53% Added +1.1m +1,111,111
3 EcoR1 Capital, LLC 8.53% of their portfolio San Francisco, CA 5,748,3995.7m $250.4m $250.4m 8.53% New
4 VANGUARD GROUP INC 0.01% of their portfolio Valley Forge, PA 5,699,6325.7m $248.3m $248.3m 0.01% Added +721.4k +721,357
5 BlackRock Inc. 0.00% of their portfolio New York, NY 3,544,3113.5m $154.4m $154.4m 0.00% Added +226.3k +226,292
6 WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio Boston, MA 3,319,9223.3m $144.6m $144.6m 0.03% Reduced -68.4k -68,443
7 Boxer Capital, LLC 7.42% of their portfolio San Diego, CA 3,201,4403.2m $139.5m $139.5m 7.42% Added +1.2m +1,201,440
8 Aviva Holdings Ltd. 87.83% of their portfolio NEW PROVIDENCE, C5 3,135,9663.1m $136.6m $136.6m 87.83% Unchanged
9 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 2,745,9682.7m $119.6m $119.6m 0.01% Added +164.2k +164,229
10 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 2,462,1322.5m $107.3m $107.3m 0.01% Reduced -382.3k -382,340
11 PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio BALTIMORE, MD 2,433,0292.4m $106.0m $106.0m 0.02% Added +655.5k +655,450
12 Artal Group S.A. 3.84% of their portfolio LUXEMBOURG, N4 2,024,2262.0m $88.2m $88.2m 3.84% Reduced -31.0k -30,955
13 ORBIMED ADVISORS LLC 1.83% of their portfolio New York, NY 1,959,0502.0m $85.3m $85.3m 1.83% Added +1.0m +1,045,400
14 Assenagon Asset Management S.A. 0.28% of their portfolio SENNINGERBERG, N4 1,825,6781.8m $79.5m $79.5m 0.28% Added +1.0m +1,016,858
15 Paradigm Biocapital Advisors LP 4.96% of their portfolio NEW YORK, NY 1,668,1161.7m $72.7m $72.7m 4.96% Added +224.4k +224,354
16 FMR LLC 0.01% of their portfolio BOSTON, MA 1,527,8281.5m $66.6m $66.6m 0.01% Added +1.4m +1,404,045
17 Camber Capital Management LP 2.35% of their portfolio BOSTON, MA 1,500,0001.5m $65.3m $65.3m 2.35% Reduced -300.0k -300,000
18 BAKER BROS. ADVISORS LP 0.35% of their portfolio NEW YORK, NY 1,409,7841.4m $61.4m $61.4m 0.35% Unchanged
19 ARMISTICE CAPITAL, LLC 1.77% of their portfolio NEW YORK, NY 1,364,0981.4m $59.4m $59.4m 1.77% Reduced -2.6m -2,613,902
20 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.12% of their portfolio Boston, MA 1,175,0001.2m $51.2m $51.2m 0.12% New
21 CITADEL ADVISORS LLC 0.05% of their portfolio MIAMI, FL 1,131,4381.1m $49.3m $49.3m 0.05% Added +649.6k +649,620
22 Rock Springs Capital Management LP 1.32% of their portfolio Baltimore, MD 1,131,2071.1m $49.3m $49.3m 1.32% Added +9.6k +9,560
23 Fiera Capital Corp 0.14% of their portfolio MONTREAL, A8 1,038,8361.0m $45.3m $45.3m 0.14% Added +346.8k +346,803
24 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.25% of their portfolio SAN FRANCISCO, CA 1,001,0001.0m $43.6m $43.6m 0.25% Not comparable
25 Candriam S.C.A. 0.28% of their portfolio STRASSEN, N4 893,763893.8k $38.9m $38.9m 0.28% Added +20.0k +20,000
26 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 881,226881.2k $38.4m $38.4m 0.00% Added +116.7k +116,743
27 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 801,268801.3k $34.9m $34.9m 0.02% Added +148.9k +148,878
28 Balyasny Asset Management L.P. 0.09% of their portfolio Chicago, IL 775,747775.7k $33.8m $33.8m 0.09% New
29 Octagon Capital Advisors LP 5.02% of their portfolio NEW YORK, NY 655,051655.1k $28.5m $28.5m 5.02% Reduced -94.9k -94,949
30 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 651,722651.7k $28.4m $28.4m 0.01% Added +179.3k +179,254
31 EVENTIDE ASSET MANAGEMENT, LLC 0.47% of their portfolio Boston, MA 600,000600.0k $26.1m $26.1m 0.47% Unchanged
32 CREDIT SUISSE AG/ 0.02% of their portfolio ZURICH, V8 544,626544.6k $23.7m $23.7m 0.02% Added +5.2k +5,176
33 Casdin Capital, LLC 2.42% of their portfolio New York, NY 498,427498.4k $21.7m $21.7m 2.42% Added +474.6k +474,613
34 NORGES BANK 0.00% of their portfolio OSLO, Q8 431,943431.9k $18.8m $18.8m 0.00% Unchanged
35 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 388,165388.2k $16.9m $16.9m 0.00% Added +60.4k +60,409
36 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 343,442343.4k $15.0m $15.0m 0.00% Reduced -92.6k -92,606
37 NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio ALBANY, NY 317,601317.6k $13.8m $13.8m 0.02% Added +84.7k +84,741
38 Logos Global Management LP 1.86% of their portfolio San Francisco, CA 300,000300.0k $13.1m $13.1m 1.86% New
39 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 298,194298.2k $13.0m $13.0m 0.01% Reduced -4.6k -4,627
40 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio BALA CYNWYD, PA 283,391283.4k $12.3m $12.3m 0.02% Added +58.3k +58,290
41 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 278,441278.4k $12.1m $12.1m 0.00% Added +46.6k +46,556
42 Woodline Partners LP 0.14% of their portfolio San Francisco, CA 278,223278.2k $12.1m $12.1m 0.14% Reduced -95.1k -95,109
43 Point72 Asset Management, L.P. 0.04% of their portfolio STAMFORD, CT 258,563258.6k $11.3m $11.3m 0.04% New
44 Rafferty Asset Management, LLC 0.06% of their portfolio New York, NY 249,612249.6k $10.9m $10.9m 0.06% Added +31.0k +30,973
45 DEUTSCHE BANK AG\ 0.01% of their portfolio FRANKFURT AM MAIN, 2M 242,561242.6k $10.6m $10.6m 0.01% Added +7.0k +7,032
46 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 240,780240.8k $10.5m $10.5m 0.00% Added +26.0k +26,022
47 INTERNATIONAL BIOTECHNOLOGY TRUST PLC 3.17% of their portfolio London, X0 216,000216.0k $9.4m $9.4m 3.17% Reduced -44.0k -44,000
48 TD Asset Management Inc 0.01% of their portfolio Toronto, A6 213,218213.2k $9.3m $9.3m 0.01% Added +141.1k +141,113
49 Verition Fund Management LLC 0.12% of their portfolio GREENWICH, CT 206,479206.5k $9.0m $9.0m 0.12% Added +198.8k +198,801
50 SILVERARC CAPITAL MANAGEMENT, LLC 3.25% of their portfolio BOSTON, MA 200,000200.0k $8.7m $8.7m 3.25% Added +108.8k +108,787
51 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 192,705192.7k $8.4m $8.4m 0.00% Added +9.3k +9,340
52 5AM Venture Management, LLC 2.41% of their portfolio SAN FRANCISCO, CA 192,500192.5k $8.4m $8.4m 2.41% Unchanged
53 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 186,926186.9k $8.1m $8.1m 0.01% Reduced -43.0k -42,957
54 SECTORAL ASSET MANAGEMENT INC 1.54% of their portfolio MONTREAL, A8 181,904181.9k $7.9m $7.9m 1.54% Added +33.4k +33,351
55 TANG CAPITAL MANAGEMENT LLC 1.11% of their portfolio SAN DIEGO, CA 180,000180.0k $7.8m $7.8m 1.11% Added +100.0k +100,000
56 Rhenman & Partners Asset Management AB 0.82% of their portfolio Stockholm, V7 175,000175.0k $7.6m $7.6m 0.82% Added +35.0k +35,000
57 Jefferies Financial Group Inc. 0.19% of their portfolio NEW YORK, NY 173,665173.7k $7.6m $7.6m 0.19% Added +30.7k +30,696
58 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 157,654157.7k $6.9m $6.9m 0.01% Added +90.0k +89,950
59 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 148,447148.4k $6.5m $6.5m 0.00% Added +39.8k +39,774
60 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 147,144147.1k $6.4m $6.4m 0.01% Reduced -437.2k -437,179
61 Granahan Investment Management, LLC 0.23% of their portfolio WALTHAM, MA 145,175145.2k $6.3m $6.3m 0.23% Reduced -112 -112
62 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 139,613139.6k $6.1m $6.1m 0.01% Reduced -123.3k -123,325
63 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 127,774127.8k $5.6m $5.6m 0.00% Added +23.9k +23,903
64 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 119,628119.6k $5.2m $5.2m 0.00% Reduced -19.9k -19,873
65 Swiss National Bank 0.00% of their portfolio ZURICH, V8 111,800111.8k $4.9m $4.9m 0.00% Added +23.2k +23,200
66 DAFNA Capital Management LLC 1.26% of their portfolio LOS ANGELES, CA 92,88792.9k $4.0m $4.0m 1.26% Reduced -1.8k -1,813
67 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 90,16390.2k $3.9m $3.9m 0.00% Added +35.0k +35,015
68 Maven Securities LTD 0.43% of their portfolio ST HELIER, Y9 90,00090.0k $3.9m $3.9m 0.43% New
69 GREAT POINT PARTNERS LLC 0.71% of their portfolio Greenwich, CT 86,30286.3k $3.8m $3.8m 0.71% New
70 ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio Berwyn, PA 82,41382.4k $3.6m $3.6m 0.00% Added +60.0k +59,968
71 ALGERT GLOBAL LLC 0.15% of their portfolio SAN FRANCISCO, CA 74,28674.3k $3.2m $3.2m 0.15% Added +770 +770
72 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 71,35571.4k $3.1m $3.1m 0.01% Added +52.2k +52,215
73 Ally Bridge Group (NY) LLC 3.59% of their portfolio NEW YORK, NY 70,28370.3k $3.1m $3.1m 3.59% New
74 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 69,87969.9k $3.0m $3.0m 0.00% Added +30.8k +30,805
75 FIL Ltd 0.00% of their portfolio HAMILTON, D0 69,38469.4k $3.0m $3.0m 0.00% Added +15.9k +15,950
76 State of New Jersey Common Pension Fund D 0.01% of their portfolio TRENTON, NJ 67,39667.4k $2.9m $2.9m 0.01% New
77 Ghisallo Capital Management LLC 0.29% of their portfolio BOSTON, MA 65,00065.0k $2.8m $2.8m 0.29% New
78 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% of their portfolio CHICAGO, IL 64,69864.7k $2.8m $2.8m 0.05% Added +5.0k +5,000
79 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio TALLAHASSEE, FL 62,59662.6k $2.7m $2.7m 0.01% Added +90 +90
80 Affinity Asset Advisors, LLC 0.86% of their portfolio NEW YORK, NY 60,42660.4k $2.6m $2.6m 0.86% New
81 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 60,26460.3k $2.6m $2.6m 0.00% Added +12.9k +12,910
82 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 60,06860.1k $2.6m $2.6m 0.00% Reduced -24.0k -24,004
83 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 60,00060.0k $2.6m $2.6m 0.00% Unchanged
84 Ghost Tree Capital, LLC 1.27% of their portfolio NEW YORK, NY 60,00060.0k $2.6m $2.6m 1.27% Reduced -140.0k -140,000
85 SIMPLEX TRADING, LLC 0.09% of their portfolio CHICAGO, IL 56,43356.4k $2.5m $2.5m 0.09% Added +12.3k +12,270
86 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 55,15555.2k $2.4m $2.4m 0.00% Added +4.1k +4,056
87 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 54,81054.8k $2.4m $2.4m 0.01% Added +16.7k +16,736
88 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 51,87151.9k $2.3m $2.3m 0.00% Added +424 +424
89 Clearline Capital LP 0.22% of their portfolio NEW YORK, NY 51,27551.3k $2.2m $2.2m 0.22% Reduced -5.1k -5,066
90 Caption Management, LLC 0.29% of their portfolio OKLAHOMA CITY, OK 51,00051.0k $2.2m $2.2m 0.29% Added +2.0k +2,000
91 SG Americas Securities, LLC 0.03% of their portfolio NEW YORK, NY 49,57849.6k $2.2m $2.2m 0.03% Added +25.3k +25,335
92 Legal & General Group Plc 0.00% of their portfolio London, X0 46,98547.0k $2.0m $2.0m 0.00% Added +8.0k +7,994
93 GTS SECURITIES LLC 0.04% of their portfolio NEW YORK, NY 46,62546.6k $2.0m $2.0m 0.04% Added +30.5k +30,451
94 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 42,64942.6k $1.9m $1.9m 0.01% Reduced -74.5k -74,502
95 PROFUND ADVISORS LLC 0.10% of their portfolio BETHESDA, MD 41,03941.0k $1.8m $1.8m 0.10% Added +2.2k +2,205
96 Jump Financial, LLC 0.07% of their portfolio Chicago, IL 40,66740.7k $1.8m $1.8m 0.07% New
97 GROUP ONE TRADING LLC 0.07% of their portfolio CHICAGO, IL 38,70638.7k $1.7m $1.7m 0.07% Added +2.7k +2,658
98 CONGRESS ASSET MANAGEMENT CO 0.01% of their portfolio BOSTON, MA 35,50935.5k $1.5m $1.5m 0.01% Added +49 +49
99 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 35,10435.1k $1.5m $1.5m 0.00% Reduced -150 -150
100 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 34,99935.0k $1.5m $1.5m 0.00% Reduced -6.2k -6,156