Vault-13

MIRATI THERAPEUTICS INC MRTX

COM · Common Stock · CUSIP 60468T105 · ISIN US60468T1051

208 institutional holders -15 vs Q1 2023
65,863,40165.9m shares reported held*
$2.4bnreported value*
23 new 83 added 66 reduced 42 sold out net bought ≈ $57.1m (+1.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($786.8k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $36.13. Options: 18 managers hold calls ($33.6m notional), 13 hold puts ($11.3m).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 244Q4 22: 233Q1 23: 223Q2 23: 208208Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 2022244
Q4 2022233
Q1 2023223
Q2 2023208

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 133 bought or addedQ4 22: 118 cut or sold outQ4 22Q1 23: 119 bought or addedQ1 23: 104 cut or sold outQ1 23Q2 23: 106 bought or addedQ2 23: 108 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 2022133118
Q1 2023119104
Q2 2023106108

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25m$50m$75m$100mQ3 22 calls: $71.0mQ3 22 puts: $87.9mQ3 22P/C 1.24Q4 22 calls: $86.2mQ4 22 puts: $34.1mQ4 22P/C 0.40Q1 23 calls: $16.7mQ1 23 puts: $10.6mQ1 23P/C 0.64Q2 23 calls: $33.6mQ2 23 puts: $11.3mQ2 23P/C 0.34
Numbers
QuarterCallsPutsP/C
Q3 2022$71.0m$87.9m1.24
Q4 2022$86.2m$34.1m0.40
Q1 2023$16.7m$10.6m0.64
Q2 2023$33.6m$11.3m0.34

Biggest buyers

RTW INVESTMENTS, LP Added +829,871+829.9k
MORGAN STANLEY Added +793,019+793.0k
WELLINGTON MANAGEMENT GROUP LLP Added +692,273+692.3k
Assenagon Asset Management S.A. Added +552,860+552.9k
Artal Group S.A. Added +517,472+517.5k
MILLENNIUM MANAGEMENT LLC Added +486,275+486.3k
Camber Capital Management LP Added +400,000+400.0k
CITADEL ADVISORS LLC Added +391,174+391.2k
ARMISTICE CAPITAL, LLC Added +286,000+286.0k
STATE STREET CORP Added +271,919+271.9k

Biggest sellers

PERCEPTIVE ADVISORS LLC Reduced -855,031-855.0k
Point72 Asset Management, L.P. Sold out -645,500-645.5k
Kynam Capital Management, LP Sold out -499,853-499.9k
Casdin Capital, LLC Reduced -486,186-486.2k
PFM Health Sciences, LP Sold out -318,948-318.9k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Reduced -272,623-272.6k
NATIONAL BANK OF CANADA /FI/ Reduced -252,200-252.2k
FMR LLC Reduced -232,383-232.4k
NORGES BANK Reduced -225,295-225.3k
BRAIDWELL LP Reduced -211,375-211.4k

Biggest calls

Artal Group S.A. New $9.0m250.0k shares
SILVERARC CAPITAL MANAGEMENT, LLC New $5.4m150.0k shares
SIMPLEX TRADING, LLC Added $4.3m119.7k shares
GROUP ONE TRADING LLC Added $3.6m100.9k shares
MOORE CAPITAL MANAGEMENT, LP New $3.6m100.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $2.0m55.4k shares
ORACLE INVESTMENT MANAGEMENT INC New $1.8m50.0k shares
MILLENNIUM MANAGEMENT LLC Reduced $1.1m30.0k shares
PERCEPTIVE ADVISORS LLC New $690.0k200.0k shares
CITADEL ADVISORS LLC Added $426.3k11.8k shares

Biggest puts

GROUP ONE TRADING LLC Added $2.9m79.9k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $2.2m59.9k shares
CITADEL ADVISORS LLC Reduced $2.0m56.7k shares
SIMPLEX TRADING, LLC Added $1.4m38.0k shares
Jefferies Financial Group Inc. Unchanged $982.7k27.2k shares
UBS Group AG Reduced $834.6k23.1k shares
Caption Management, LLC New $462.5k12.8k shares
JANE STREET GROUP, LLC Added $310.7k8.6k shares
Walleye Trading LLC Reduced $137.3k3.8k shares
PEAK6 Investments LLC New $75.9k2.1k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 2.72% of their portfolio NEW YORK, NY 5,555,5555.6m $200.7m $200.7m 2.72% Unchanged
2 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 4,978,2755.0m $179.9m $179.9m 0.00% Reduced -71.1k -71,100
3 RTW INVESTMENTS, LP 3.08% of their portfolio NEW YORK, NY 4,472,9854.5m $161.6m $161.6m 3.08% Added +829.9k +829,871
4 ARMISTICE CAPITAL, LLC 3.61% of their portfolio NEW YORK, NY 3,978,0004.0m $143.7m $143.7m 3.61% Added +286.0k +286,000
5 WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio Boston, MA 3,388,3653.4m $122.4m $122.4m 0.02% Added +692.3k +692,273
6 BlackRock Inc. 0.00% of their portfolio New York, NY 3,318,0193.3m $119.9m $119.9m 0.00% Added +81.1k +81,140
7 Aviva Holdings Ltd. 93.06% of their portfolio NEW PROVIDENCE, C5 3,135,9663.1m $113.3m $113.3m 93.06% Unchanged
8 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 2,844,4722.8m $102.8m $102.8m 0.01% Added +793.0k +793,019
9 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,581,7392.6m $93.3m $93.3m 0.00% Added +271.9k +271,919
10 Artal Group S.A. 2.38% of their portfolio LUXEMBOURG, N4 2,055,1812.1m $74.3m $74.3m 2.38% Added +517.5k +517,472
11 Boxer Capital, LLC 3.35% of their portfolio San Diego, CA 2,000,0002.0m $72.3m $72.3m 3.35% Unchanged
12 Camber Capital Management LP 2.12% of their portfolio BOSTON, MA 1,800,0001.8m $65.0m $65.0m 2.12% Added +400.0k +400,000
13 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,777,5791.8m $64.2m $64.2m 0.01% Added +6.6k +6,638
14 Paradigm Biocapital Advisors LP 4.22% of their portfolio NEW YORK, NY 1,443,7621.4m $52.2m $52.2m 4.22% Added +47.0k +46,983
15 BAKER BROS. ADVISORS LP 0.29% of their portfolio NEW YORK, NY 1,409,7841.4m $50.9m $50.9m 0.29% Unchanged
16 Rock Springs Capital Management LP 0.96% of their portfolio Baltimore, MD 1,121,6471.1m $40.5m $40.5m 0.96% Added +56.4k +56,386
17 ORBIMED ADVISORS LLC 0.60% of their portfolio New York, NY 913,650913.6k $33.0m $33.0m 0.60% Unchanged
18 Candriam S.C.A. 0.23% of their portfolio STRASSEN, N4 873,763873.8k $31.6m $31.6m 0.23% Added +109.5k +109,498
19 Assenagon Asset Management S.A. 0.11% of their portfolio SENNINGERBERG, N4 808,820808.8k $29.2m $29.2m 0.11% Added +552.9k +552,860
20 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 764,483764.5k $27.6m $27.6m 0.00% Added +29.2k +29,195
21 Octagon Capital Advisors LP 3.78% of their portfolio NEW YORK, NY 750,000750.0k $27.1m $27.1m 3.78% Unchanged
22 PERCEPTIVE ADVISORS LLC 0.75% of their portfolio NEW YORK, NY 719,103719.1k $26.0m $26.0m 0.75% Reduced -855.0k -855,031
23 Fiera Capital Corp 0.07% of their portfolio MONTREAL, A8 692,033692.0k $25.0m $25.0m 0.07% Reduced -17.5k -17,494
24 FRANKLIN RESOURCES INC 0.01% of their portfolio San Mateo, CA 652,390652.4k $23.6m $23.6m 0.01% Added +22 +22
25 EVENTIDE ASSET MANAGEMENT, LLC 0.37% of their portfolio Boston, MA 600,000600.0k $21.7m $21.7m 0.37% Added +228.9k +228,898
26 MARSHALL WACE, LLP 0.05% of their portfolio LONDON, X0 584,323584.3k $21.1m $21.1m 0.05% Added +31.7k +31,709
27 CREDIT SUISSE AG/ 0.02% of their portfolio ZURICH, V8 539,450539.5k $19.5m $19.5m 0.02% Added +16.1k +16,083
28 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 505,309505.3k $18.3m $18.3m 0.02% Added +486.3k +486,275
29 CITADEL ADVISORS LLC 0.02% of their portfolio MIAMI, FL 481,818481.8k $17.4m $17.4m 0.02% Added +391.2k +391,174
30 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 472,468472.5k $17.1m $17.1m 0.01% Added +167.9k +167,874
31 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 436,048436.0k $15.8m $15.8m 0.00% Added +5.6k +5,554
32 NORGES BANK 0.00% of their portfolio OSLO, Q8 431,943431.9k $15.6m $15.6m 0.00% Reduced -225.3k -225,295
33 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.07% of their portfolio JUPITER, FL 406,035406.0k $14.7m $14.7m 0.07% Reduced -272.6k -272,623
34 Woodline Partners LP 0.16% of their portfolio San Francisco, CA 373,332373.3k $13.5m $13.5m 0.16% Added +107.2k +107,232
35 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 327,756327.8k $11.8m $11.8m 0.00% Reduced -58.5k -58,494
36 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 302,821302.8k $11.3m $11.3m 0.01% Unchanged
37 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 262,938262.9k $9.5m $9.5m 0.01% Added +17.4k +17,352
38 INTERNATIONAL BIOTECHNOLOGY TRUST PLC 2.86% of their portfolio London, X0 260,000260.0k $9.4m $9.4m 2.86% Added +16.0k +16,000
39 BRAIDWELL LP 0.28% of their portfolio STAMFORD, CT 240,625240.6k $8.7m $8.7m 0.28% Reduced -211.4k -211,375
40 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 235,529235.5k $8.5m $8.5m 0.00% Reduced -3.3k -3,326
41 NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio ALBANY, NY 232,860232.9k $8.4m $8.4m 0.01% Added +643 +643
42 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 231,885231.9k $8.4m $8.4m 0.00% Reduced -28.5k -28,524
43 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 229,883229.9k $8.3m $8.3m 0.01% Added +80.8k +80,755
44 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio BALA CYNWYD, PA 225,101225.1k $8.1m $8.1m 0.01% Reduced -137.5k -137,511
45 Allspring Global Investments Holdings, LLC 0.01% of their portfolio CHARLOTTE, NC 222,737222.7k $8.0m $8.0m 0.01% Reduced -10.3k -10,302
46 Rafferty Asset Management, LLC 0.04% of their portfolio New York, NY 218,639218.6k $7.9m $7.9m 0.04% Added +45.1k +45,123
47 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 214,758214.8k $7.8m $7.8m 0.00% Added +11.2k +11,151
48 Ghost Tree Capital, LLC 2.61% of their portfolio NEW YORK, NY 200,000200.0k $7.2m $7.2m 2.61% Added +60.0k +60,000
49 JACOBS LEVY EQUITY MANAGEMENT, INC 0.04% of their portfolio FLORHAM PARK, NJ 195,320195.3k $7.1m $7.1m 0.04% Added +10.6k +10,604
50 5AM Venture Management, LLC 1.73% of their portfolio SAN FRANCISCO, CA 192,500192.5k $7.0m $7.0m 1.73% New
51 EDMOND DE ROTHSCHILD HOLDING S.A. 0.13% of their portfolio CHAMBESY, V8 184,060184.1k $6.7m $6.7m 0.13% Unchanged
52 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 183,365183.4k $6.6m $6.6m 0.00% Added +13.1k +13,101
53 ORACLE INVESTMENT MANAGEMENT INC 5.21% of their portfolio GREENWICH, CT 152,600152.6k $5.5m $5.5m 5.21% Reduced -48.8k -48,800
54 SECTORAL ASSET MANAGEMENT INC 0.89% of their portfolio MONTREAL, A8 148,553148.6k $5.4m $5.4m 0.89% Added +20.1k +20,147
55 Granahan Investment Management, LLC 0.16% of their portfolio WALTHAM, MA 145,287145.3k $5.2m $5.2m 0.16% Added +16.2k +16,197
56 Jefferies Financial Group Inc. 0.11% of their portfolio NEW YORK, NY 142,969143.0k $5.2m $5.2m 0.11% Added +92.5k +92,549
57 Rhenman & Partners Asset Management AB 0.53% of their portfolio Stockholm, V7 140,000140.0k $5.1m $5.1m 0.53% Reduced -75.0k -75,000
58 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 139,501139.5k $5.0m $5.0m 0.00% Added +67.9k +67,858
59 Schonfeld Strategic Advisors LLC 0.04% of their portfolio NEW YORK, NY 129,636129.6k $4.7m $4.7m 0.04% Added +106.8k +106,837
60 UBS Group AG 0.00% of their portfolio ZURICH, V8 124,768124.8k $4.5m $4.5m 0.00% Added +43.3k +43,336
61 FMR LLC 0.00% of their portfolio BOSTON, MA 123,783123.8k $4.5m $4.5m 0.00% Reduced -232.4k -232,383
62 Connor, Clark & Lunn Investment Management Ltd. 0.02% of their portfolio VANCOUVER, A1 117,151117.2k $4.2m $4.2m 0.02% Reduced -19.3k -19,335
63 Man Group plc 0.01% of their portfolio LONDON, X0 109,491109.5k $4.0m $4.0m 0.01% New
64 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 108,673108.7k $3.9m $3.9m 0.00% Added +6.7k +6,707
65 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 103,871103.9k $3.8m $3.8m 0.00% Reduced -38.0k -37,989
66 ExodusPoint Capital Management, LP 0.04% of their portfolio NEW YORK, NY 98,73898.7k $3.6m $3.6m 0.04% Reduced -65.0k -65,004
67 Polar Asset Management Partners Inc. 0.07% of their portfolio TORONTO, A6 98,50098.5k $3.6m $3.6m 0.07% New
68 DAFNA Capital Management LLC 0.94% of their portfolio LOS ANGELES, CA 94,70094.7k $3.4m $3.4m 0.94% Added +21.1k +21,100
69 SILVERARC CAPITAL MANAGEMENT, LLC 1.11% of their portfolio BOSTON, MA 91,21391.2k $3.3m $3.3m 1.11% New
70 NATIONAL BANK OF CANADA /FI/ 0.01% of their portfolio MONTREAL, A8 89,00089.0k $3.4m $3.4m 0.01% Reduced -252.2k -252,200
71 Swiss National Bank 0.00% of their portfolio ZURICH, V8 88,60088.6k $3.2m $3.2m 0.00% Added +1.6k +1,600
72 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 84,07284.1k $3.0m $3.0m 0.00% Reduced -71.3k -71,287
73 TANG CAPITAL MANAGEMENT LLC 0.43% of their portfolio SAN DIEGO, CA 80,00080.0k $2.9m $2.9m 0.43% New
74 Handelsbanken Fonder AB 0.01% of their portfolio STOCKHOLM, V7 76,90076.9k $2.8m $2.8m 0.01% Added +1.3k +1,300
75 ALGERT GLOBAL LLC 0.12% of their portfolio SAN FRANCISCO, CA 73,51673.5k $2.7m $2.7m 0.12% Added +10.3k +10,292
76 HRT FINANCIAL LP 0.03% of their portfolio NEW YORK, NY 73,27673.3k $2.6m $2.6m 0.03% Reduced -8.0k -8,030
77 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 72,10572.1k $2.6m $2.6m 0.00% Added +4.7k +4,700
78 California Public Employees Retirement System 0.00% of their portfolio Sacramento, CA 69,45469.5k $2.5m $2.5m 0.00% Unchanged
79 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 67,70467.7k $2.4m $2.4m 0.00% Reduced -91.3k -91,289
80 Tekla Capital Management LLC 0.09% of their portfolio Boston, MA 65,49065.5k $2.4m $2.4m 0.09% Unchanged
81 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio TALLAHASSEE, FL 62,50662.5k $2.3m $2.3m 0.01% Reduced -1.4k -1,366
82 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 60,00060.0k $2.2m $2.2m 0.00% Unchanged
83 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% of their portfolio CHICAGO, IL 59,69859.7k $2.2m $2.2m 0.05% Added +12.4k +12,448
84 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 58,59758.6k $2.1m $2.1m 0.00% Reduced -5.7k -5,677
85 Clearline Capital LP 0.26% of their portfolio NEW YORK, NY 56,34156.3k $2.0m $2.0m 0.26% New
86 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 55,14855.1k $2.0m $2.0m 0.00% Added +3.8k +3,769
87 FIL Ltd 0.00% of their portfolio HAMILTON, D0 53,43453.4k $1.9m $1.9m 0.00% New
88 Parallax Volatility Advisers, L.P. 0.06% of their portfolio San Francisco, CA 51,98852.0k $1.9m $1.9m 0.06% Added +26.7k +26,736
89 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 51,44751.4k $1.9m $1.9m 0.00% Added +3.0k +3,010
90 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 51,09951.1k $1.8m $1.8m 0.00% Reduced -1.0k -1,018
91 Caption Management, LLC 0.31% of their portfolio OKLAHOMA CITY, OK 49,00049.0k $1.8m $1.8m 0.31% New
92 Skandinaviska Enskilda Banken AB (publ) 0.01% of their portfolio STOCKHOLM, V7 48,35348.4k $1.7m $1.7m 0.01% Reduced -46.6k -46,559
93 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 47,35447.4k $1.7m $1.7m 0.00% Reduced -2.4k -2,408
94 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 44,30244.3k $1.6m $1.6m 0.00% Reduced -5.9k -5,912
95 SIMPLEX TRADING, LLC 0.07% of their portfolio CHICAGO, IL 44,16344.2k $1.6m $1.6m 0.07% Added +12.4k +12,375
96 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 41,15541.2k $1.5m $1.5m 0.00% Reduced -6.6k -6,607
97 Walleye Capital LLC 0.03% of their portfolio NEW YORK, NY 39,56439.6k $1.4m $1.4m 0.03% Reduced -142.9k -142,916
98 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 39,07439.1k $1.4m $1.4m 0.00% Reduced -20.8k -20,774
99 Legal & General Group Plc 0.00% of their portfolio London, X0 38,99139.0k $1.4m $1.4m 0.00% Reduced -1.2k -1,244
100 PROFUND ADVISORS LLC 0.08% of their portfolio BETHESDA, MD 38,83438.8k $1.4m $1.4m 0.08% Added +7.3k +7,307