LYRA THERAPEUTICS INC LYRA
COM · Common Stock · CUSIP 55234L105
52
institutional holders
-28 vs Q1 2024
32.8m
shares reported held*
$9.1mreported value*
13 new
15 added
13 reduced
42 sold out
net sold ≈ $3.6m (-13.1m shares)
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.28. Options: 5 managers hold calls ($87.7k notional), 3 hold puts ($166).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 39 |
| Q4 2022 | 38 |
| Q1 2023 | 32 |
| Q2 2023 | 40 |
| Q3 2023 | 46 |
| Q4 2023 | 61 |
| Q1 2024 | 80 |
| Q2 2024 | 52 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Bought or addedCut or sold out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 16 | 12 |
| Q1 2023 | 7 | 11 |
| Q2 2023 | 23 | 8 |
| Q3 2023 | 25 | 11 |
| Q4 2023 | 41 | 10 |
| Q1 2024 | 54 | 19 |
| Q2 2024 | 28 | 55 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
CallsPuts
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $964.7k | $5.9k | 0.01 |
| Q4 2023 | $1.3m | $27.1k | 0.02 |
| Q1 2024 | $1.9m | $8.1k | 0.00 |
| Q2 2024 | $87.7k | $166 | 0.00 |
Biggest buyers
| BlackRock Inc. | Added | +2.7m |
| ACADIAN ASSET MANAGEMENT LLC | New | +985.6k |
| MORGAN STANLEY | Added | +618.6k |
| TWO SIGMA ADVISERS, LP | Added | +537.7k |
| CITADEL ADVISORS LLC | Added | +433.7k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +395.7k |
| NEW YORK STATE COMMON RETIREMENT FUND | New | +382.9k |
| TWO SIGMA INVESTMENTS, LP | Added | +307.1k |
| VANGUARD GROUP INC | Added | +249.4k |
| STATE STREET CORP | Added | +133.6k |
Biggest sellers
| Nantahala Capital Management, LLC | Sold out | -2.8m |
| Point72 Asset Management, L.P. | Sold out | -2.7m |
| Venrock Adviser, LLC | Sold out | -2.6m |
| PURA VIDA INVESTMENTS, LLC | Sold out | -1.4m |
| Ally Bridge Group (NY) LLC | Sold out | -1.0m |
| Tri Locum Partners LP | Sold out | -978.8k |
| Vestal Point Capital, LP | Sold out | -800.0k |
| Verition Fund Management LLC | Sold out | -768.2k |
| Laurion Capital Management LP | Sold out | -747.8k |
| Woodline Partners LP | Sold out | -676.6k |
Biggest calls
| Caption Management, LLC | New | $68.2k246.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $13.0k46.3k shares |
| CITADEL ADVISORS LLC | Added | $6.5k23.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Reduced | $0100 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $166600 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | New | $01.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| PERCEPTIVE ADVISORS LLC 13D · may seek influence filed 2025-08-14 | 15.6% |
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| PERCEPTIVE ADVISORS LLC 0.09% of their portfolio | 12.8m $3.5m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 4.8m $1.3m | Added +433.7k |
| BlackRock Inc. 0.00% of their portfolio | 2.8m $783.1k | Added +2.7m |
| SAMSARA BIOCAPITAL, LLC 0.16% of their portfolio | 2.8m $769.3k | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.7m $478.9k | Added +249.4k |
| Ikarian Capital, LLC 0.09% of their portfolio | 1.1m $292.4k | Unchanged |
| Rosalind Advisors, Inc. 0.23% of their portfolio | 1.0m $286.3k | Reduced -109.8k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 985.6k $271.0k | New |
| MORGAN STANLEY 0.00% of their portfolio | 811.7k $224.6k | Added +618.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 755.1k $209.0k | Added +395.7k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 681.6k $188.6k | Added +537.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 490.9k $135.8k | Added +307.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 382.9k $105.9k | New |
| STATE STREET CORP 0.00% of their portfolio | 259.8k $71.9k | Added +133.6k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 232.7k $64.4k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 129.1k $35.0k | New |
| Clearline Capital LP 0.00% of their portfolio | 119.1k $33.0k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 111.6k $30.9k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 86.5k $23.9k | Reduced -73.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 83.9k $23.2k | Added +23.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 77.4k $21.4k | New |
| Alpine Global Management, LLC 0.00% of their portfolio | 46.4k $12.8k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 43.4k $12.0k | Added +43.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 42.7k $11.8k | Reduced -115.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 41.3k $11.4k | Reduced -177.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 35.2k $9.7k | Reduced -308.2k |
| XTX Topco Ltd 0.00% of their portfolio | 34.0k $9.4k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 33.1k $9.2k | New |
| LETKO, BROSSEAU & ASSOCIATES INC 0.00% of their portfolio | 31.9k $8.8k | Unchanged |
| Virtu Financial LLC 0.00% of their portfolio | 31.7k $9.0k | Added +19.8k |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 27.5k $7.6k | Added +7.0k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 26.0k $7.5k | First filing |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 24.4k $6.7k | Reduced -310.3k |
| Invesco Ltd. 0.00% of their portfolio | 22.8k $6.3k | Reduced -532.4k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 21.5k $5.9k | Reduced -169.5k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 20.4k $5.6k | Reduced -385.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 17.6k $4.9k | Added +17.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 17.5k $0 | New |
| BARCLAYS PLC 0.00% of their portfolio | 16.6k $4.6k | Reduced -16.2k |
| UBS Group AG 0.00% of their portfolio | 14.7k $4.1k | Added +14.7k |
| DLK Investment Management, LLC 0.00% of their portfolio | 12.0k $3.3k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 10.7k $2.9k | Reduced -108.2k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.8k $1.9k | Reduced -2.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 4.9k $1.0k | Added +4.2k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.7k $1.3k | New |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 3.7k $1.1k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.5k $970 | New |
| AMALGAMATED BANK 0.00% of their portfolio | 1.7k $0 | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 1.4k $383 | Reduced -622 |
| COMERICA BANK 0.00% of their portfolio | 1.2k $321 | Unchanged |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 38 $11 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |