LYELL IMMUNOPHARMA INC
COM · CUSIP 55083R104
96
institutional holders
+3 vs Q3 2022
116.7m
shares reported held*
$404.8mreported value*
15 new
32 added
20 reduced
13 sold out
net bought ≈ $14.3m (+4.1m shares)
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $3.47. Options: 4 managers hold calls ($48.4k notional), 2 hold puts ($6.9k).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 93 |
| Q4 2022 | 96 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
CallsPuts
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $15.0k | $0 | 0.00 |
| Q4 2022 | $48.4k | $6.9k | 0.14 |
Biggest buyers
| STATE STREET CORP | Added | +3.4m |
| GOLDMAN SACHS GROUP INC | Added | +827.4k |
| BlackRock Inc. | Added | +441.9k |
| BANK OF AMERICA CORP /DE/ | Added | +392.6k |
| UBS Group AG | Added | +390.7k |
| Rafferty Asset Management, LLC | Added | +375.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Added | +228.6k |
| VANGUARD GROUP INC | Added | +184.6k |
| TWO SIGMA INVESTMENTS, LP | New | +164.3k |
| NORTHERN TRUST CORP | Added | +149.8k |
Biggest sellers
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -1.6m |
| FMR LLC | Reduced | -323.3k |
| Invesco Ltd. | Reduced | -255.3k |
| MORGAN STANLEY | Reduced | -196.2k |
| Walleye Capital LLC | Reduced | -162.2k |
| KETTLE HILL CAPITAL MANAGEMENT, LLC | Sold out | -158.4k |
| Nuveen Asset Management, LLC | Reduced | -86.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -65.9k |
| D. E. Shaw & Co., Inc. | Reduced | -47.4k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -40.7k |
Biggest calls
| JANE STREET GROUP, LLC | New | $35.0k10.1k shares |
| CITADEL ADVISORS LLC | New | $9.4k2.7k shares |
| SIMPLEX TRADING, LLC | Added | $4.0k1.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $6.9k2.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARCH Venture Fund IX, L.P. 13G · exempt (held before listing) filed 2025-02-14 | 13.1% |
| Foresite Capital Fund IV, L.P. 13G · passive investor +2.5 pts · filed 2025-05-15 | 9.2% |
| Explore Investments LLC/DE 13G · passive investor new · filed 2025-08-19 | 5.4% |
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| MWG Management Ltd. 35.72% of their portfolio | 20.2m $70.0m | Unchanged |
| Orland Properties Ltd 27.91% of their portfolio | 15.1m $52.4m | First filing |
| VANGUARD GROUP INC 0.00% of their portfolio | 12.6m $43.7m | Added +184.6k |
| BlackRock Inc. 0.00% of their portfolio | 12.2m $42.2m | Added +441.9k |
| Foresite Capital Management IV, LLC 14.82% of their portfolio | 10.0m $34.7m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 8.8m $30.4m | Added +3.4m |
| Alphabet Inc. 1.18% of their portfolio | 5.9m $20.4m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 3.7m $12.8m | Reduced -1.6m |
| MIC Capital Management UK LLP 2.10% of their portfolio | 3.1m $10.6m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.1m $10.6m | Added +101.4k |
| HSG Holding Ltd 1.07% of their portfolio | 3.0m $10.6m | Unchanged |
| FMR LLC 0.00% of their portfolio | 3.0m $10.3m | Reduced -323.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.2m $7.6m | Added +149.8k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 1.3m $4.5m | Added +228.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.2m $4.2m | Added +827.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 1.1m $3.9m | Added +20.7k |
| BAILLIE GIFFORD & CO 0.00% of their portfolio | 761.3k $2.6m | Added +6.2k |
| Artal Group S.A. 0.14% of their portfolio | 700.0k $2.4m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 656.2k $2.3m | Reduced -2.5k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 642.5k $2.2m | Added +392.6k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 588.2k $2.0m | Unchanged |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 581.4k $2.0m | Added +375.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 572.1k $2.0m | Added +52.2k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 513.2k $1.8m | Reduced -1 |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 497.0k $1.7m | Reduced -86.7k |
| UBS Group AG 0.00% of their portfolio | 411.0k $1.4m | Added +390.7k |
| BARCLAYS PLC 0.00% of their portfolio | 335.4k $1.2m | First filing |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 307.4k $1.1m | Added +30.5k |
| CITIGROUP INC 0.00% of their portfolio | 270.6k $939.2k | Added +64.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 263.2k $913.0k | Reduced -4.5k |
| Vident Investment Advisory, LLC 0.03% of their portfolio | 222.7k $772.7k | Added +90.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 219.6k $735.1k | Added +1.1k |
| MORGAN STANLEY 0.00% of their portfolio | 218.9k $759.5k | Reduced -196.2k |
| TD Asset Management Inc 0.00% of their portfolio | 179.7k $623.5k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 164.3k $570.2k | New |
| BBR PARTNERS, LLC 0.06% of their portfolio | 164.0k $569.2k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 149.5k $518.6k | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 134.6k $467.0k | Added +15.3k |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 124.8k $433.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 117.7k $408.6k | Reduced -48 |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 100.0k $329.0k | Unchanged |
| Eagle Health Investments LP 0.08% of their portfolio | 100.0k $347.0k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 92.5k $321.0k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 91.6k $317.7k | Added +125 |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 81.8k $284.0k | Reduced -298 |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 74.9k $260.0k | Added +1.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 69.4k $240.9k | Added +1.1k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 67.4k $234.0k | Unchanged |
| SG Americas Securities, LLC 0.00% of their portfolio | 61.5k $213.0k | Added +14.6k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 59.9k $207.7k | Reduced -47.4k |
| Walleye Capital LLC 0.00% of their portfolio | 58.8k $204.0k | Reduced -162.2k |
| Invesco Ltd. 0.00% of their portfolio | 55.7k $193.2k | Reduced -255.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 55.3k $191.9k | Reduced -65.9k |
| Erste Asset Management GmbH 0.00% of their portfolio | 54.0k $177.7k | Unchanged |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 48.9k $169.5k | Added +3.2k |
| ProShare Advisors LLC 0.00% of their portfolio | 42.9k $148.8k | Added +3.0k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 39.6k $137.5k | Added +13.5k |
| VIRTUS ADVISERS, LLC 0.07% of their portfolio | 39.3k $136.5k | Added +16.2k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 32.3k $111.9k | Added +3.7k |
| E Fund Management Co., Ltd. 0.01% of their portfolio | 30.2k $105.0k | Added +16.0k |
| Alpine Global Management, LLC 0.03% of their portfolio | 27.1k $94.0k | New |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 23.3k $80.8k | Reduced -70 |
| Walleye Trading LLC 0.00% of their portfolio | 22.6k $78.3k | Reduced -18.9k |
| AMALGAMATED BANK 0.00% of their portfolio | 22.1k $77.0k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 21.5k $74.0k | Added +19.4k |
| Woodline Partners LP 0.00% of their portfolio | 20.7k $72.0k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 17.1k $59.2k | New |
| Clarius Group, LLC 0.01% of their portfolio | 16.4k $57.0k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 16.1k $56.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 16.0k $55.8k | Unchanged |
| XTX Topco Ltd 0.01% of their portfolio | 15.6k $54.2k | New |
| Adero Partners, LLC 0.01% of their portfolio | 13.0k $45.3k | Unchanged |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 13.0k $38.7k | Unchanged |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 12.6k $43.6k | Added +80 |
| MACKENZIE FINANCIAL CORP 0.00% of their portfolio | 11.2k $38.9k | Unchanged |
| ZACKS INVESTMENT MANAGEMENT 0.00% of their portfolio | 10.8k $37.6k | New |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 10.7k $37.3k | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 10.6k $36.8k | New |
| Mariner, LLC 0.00% of their portfolio | 10.2k $35.0k | New |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 8.3k $28.0k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 7.9k $27.0k | Added +7.7k |
| Aquatic Capital Management LLC 0.00% of their portfolio | 7.8k $27.0k | New |
| STRS OHIO 0.00% of their portfolio | 5.4k $18.0k | Unchanged |
| Amundi 0.00% of their portfolio | 4.2k $13.7k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.0k $10.0k | Reduced -5.5k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 2.5k $8.8k | Added +212 |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 1.6k $5.5k | Reduced -14.0k |
| Sargent Bickham Lagudis LLC 0.00% of their portfolio | 1.0k $3.5k | New |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 917 $3.0k | Unchanged |
| US BANCORP \DE\ 0.00% of their portfolio | 749 $2.6k | New |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 144 $0 | Reduced -5.9k |
| COMERICA SECURITIES,INC. 0.00% of their portfolio | 45 $156 | New |
| Covestor Ltd 0.00% of their portfolio | 27 $0 | Reduced -11 |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 7 $24 | Reduced -986 |
| SJS Investment Consulting Inc. 0.00% of their portfolio | 1 $3 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |