LIGAND PHARMACEUTICALS INC LGND
COM NEW · Common Stock · CUSIP 53220K504
Biopharmaceutical company based out of La Jolla, California
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- Founded1987
- Websiteligand.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.2m this quarter). Holder counts are more reliable. Shares outstanding: 19.6m as of 2025-08-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $113.69. Options: 4 managers hold calls ($1.1m notional), 2 hold puts ($11.4k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 204 |
| Q4 2022 | 197 |
| Q1 2023 | 213 |
| Q2 2023 | 204 |
| Q3 2023 | 197 |
| Q4 2023 | 211 |
| Q1 2024 | 222 |
| Q2 2024 | 235 |
| Q3 2024 | 243 |
| Q4 2024 | 259 |
| Q1 2025 | 263 |
| Q2 2025 | 272 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 87 | 104 |
| Q4 2023 | 98 | 88 |
| Q1 2024 | 95 | 90 |
| Q2 2024 | 122 | 100 |
| Q3 2024 | 131 | 81 |
| Q4 2024 | 139 | 84 |
| Q1 2025 | 132 | 112 |
| Q2 2025 | 140 | 111 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $5.9m | $930.8k | 0.16 |
| Q4 2024 | $3.6m | $567.2k | 0.16 |
| Q1 2025 | $998.8k | $860.3k | 0.86 |
| Q2 2025 | $1.1m | $11.4k | 0.01 |
Biggest buyers
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +336.5k |
| Ranger Investment Management, L.P. | Added | +109.9k |
| Private Capital Management, LLC | Added | +81.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Added | +62.0k |
| CITADEL ADVISORS LLC | New | +41.9k |
| RICE HALL JAMES & ASSOCIATES, LLC | Added | +40.1k |
| VANGUARD GROUP INC | Added | +33.6k |
| JANUS HENDERSON GROUP PLC | Added | +33.2k |
| Clark Capital Management Group, Inc. | Added | +27.1k |
| Invesco Ltd. | Added | +27.0k |
Biggest sellers
| CASTLEARK MANAGEMENT LLC | Sold out | -66.5k |
| CenterBook Partners LP | Reduced | -54.8k |
| KORNITZER CAPITAL MANAGEMENT INC /KS | Reduced | -44.3k |
| Lisanti Capital Growth, LLC | Reduced | -41.9k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -40.4k |
| MORGAN STANLEY | Reduced | -36.7k |
| TOWNSQUARE CAPITAL LLC | Reduced | -32.5k |
| JANE STREET GROUP, LLC | Reduced | -31.5k |
| Advisor Resource Council | Sold out | -22.4k |
| GOLDMAN SACHS GROUP INC | Reduced | -21.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $625.2k5.5k shares |
| CITADEL ADVISORS LLC | Added | $397.9k3.5k shares |
| GROUP ONE TRADING LLC | New | $90.9k800 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | New | $11.4k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -1.1 pts · filed 2025-10-17 | 14.5% |
| Invesco Ltd. 13G · institution new · filed 2026-08-13 | 6.1% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.6% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.2 pts · filed 2025-11-14 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 1 | $237.5k | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 2 | $153.0k | — |
| Q2 2024 | 0 | — | 4 | $3.6m | — |
| Q3 2024 | 1 | $243.5k | 3 | $5.9m | — |
| Q4 2024 | 0 | — | 2 | $542.3k | — |
| Q1 2025 | 0 | — | 1 | $575.1k | — |
| Q2 2025 | 2 | $1.2m | 1 | $218.3k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-23 | Reardon Andrew CLO & Secretary | Sold | $57.0k500 shares |
| 2025-06-10 | Reardon Andrew CLO & Secretary | Sold | $57.3k500 shares |
| 2025-05-15 | Reardon Andrew CLO & Secretary | Sold | $104.0k1.0k shares |
| 2025-05-09 | Davis Todd C Chief Executive Officer, director | Bought | $1.0m9.5k shares |
| 2025-05-09 | Espinoza Octavio Chief Financial Officer | Bought | $156.1k1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.01% of their portfolio | 2.9m $331.2m | Reduced -6.5k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.1m $237.5m | Added +33.6k |
| JANUS HENDERSON GROUP PLC 0.06% of their portfolio | 1.1m $120.6m | Added +33.2k |
| MACQUARIE GROUP LTD 0.13% of their portfolio | 926.6k $105.3m | Added +20.3k |
| STATE STREET CORP 0.00% of their portfolio | 749.8k $85.2m | Added +22.6k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 704.5k $80.1m | Reduced -40.4k |
| CONGRESS ASSET MANAGEMENT CO 0.51% of their portfolio | 647.9k $73.7m | Added +5.2k |
| Stephens Investment Management Group LLC 0.91% of their portfolio | 604.8k $68.8m | Reduced -2.4k |
| Chicago Capital, LLC 1.60% of their portfolio | 571.8k $65.0m | Added +17.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 488.8k $55.6m | Added +24.3k |
| LOOMIS SAYLES & CO L P 0.06% of their portfolio | 410.9k $46.7m | Reduced -9.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 391.8k $44.5m | Added +336.5k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 339.7k $38.6m | Added +62.0k |
| RICE HALL JAMES & ASSOCIATES, LLC 2.07% of their portfolio | 337.3k $38.3m | Added +40.1k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 307.8k $35.0m | Added +19.8k |
| ASHFORD CAPITAL MANAGEMENT INC 4.04% of their portfolio | 302.5k $34.4m | Added +4.5k |
| Ranger Investment Management, L.P. 2.38% of their portfolio | 300.0k $34.1m | Added +109.9k |
| VILLERE ST DENIS J & CO LLC 3.14% of their portfolio | 287.1k $32.6m | Reduced -1.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 276.8k $31.5m | Reduced -17.0k |
| Impax Asset Management Group plc 0.17% of their portfolio | 260.2k $29.6m | Reduced -20.0k |
| Invesco Ltd. 0.00% of their portfolio | 229.9k $26.1m | Added +27.0k |
| Private Capital Management, LLC 2.64% of their portfolio | 229.3k $26.1m | Added +81.1k |
| Aberdeen Group plc 0.04% of their portfolio | 229.2k $26.1m | Added +13.0k |
| MORGAN STANLEY 0.00% of their portfolio | 202.4k $23.0m | Reduced -36.7k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 186.1k $21.2m | Reduced -258 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 176.1k $20.0m | Added +7.2k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.07% of their portfolio | 162.8k $18.5m | Added +5.6k |
| Driehaus Capital Management LLC 0.15% of their portfolio | 161.2k $18.3m | Reduced -1.0k |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 145.5k $16.5m | Added +10.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 128.1k $14.6m | Added +1.5k |
| Granite Investment Partners, LLC 0.69% of their portfolio | 124.5k $14.1m | Reduced -8.7k |
| Penn Capital Management Company, LLC 1.18% of their portfolio | 120.4k $13.7m | Reduced -455 |
| Legal & General Group Plc 0.00% of their portfolio | 118.3k $13.5m | Added +16.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 115.8k $13.2m | Added +15.3k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 109.7k $12.5m | Reduced -17.3k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 106.1k $12.1m | Reduced -1.4k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 101.8k $11.6m | Reduced -1.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio | 99.5k $11.3m | Unchanged |
| CW Advisors, LLC 0.10% of their portfolio | 94.4k $10.7m | Reduced -1.9k |
| KORNITZER CAPITAL MANAGEMENT INC /KS 0.21% of their portfolio | 91.2k $10.4m | Reduced -44.3k |
| Allspring Global Investments Holdings, LLC 0.01% of their portfolio | 76.0k $8.6m | Reduced -20.4k |
| Dana Investment Advisors, Inc. 0.28% of their portfolio | 73.2k $8.3m | Reduced -1.1k |
| Clark Capital Management Group, Inc. 0.06% of their portfolio | 71.1k $8.1m | Added +27.1k |
| Pictet Asset Management Holding SA 0.01% of their portfolio | 69.6k $7.9m | Reduced -2.8k |
| Public Sector Pension Investment Board 0.03% of their portfolio | 65.8k $7.5m | Added +5.9k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 63.7k $7.2m | Reduced -21.1k |
| Uniplan Investment Counsel, Inc. 0.72% of their portfolio | 63.0k $7.2m | Reduced -5.8k |
| ESSEX INVESTMENT MANAGEMENT CO LLC 1.26% of their portfolio | 60.8k $6.9m | Reduced -892 |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 59.5k $6.8m | Added +2.1k |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 58.7k $6.7m | Added +28 |
| CIBC WORLD MARKET INC. 0.01% of their portfolio | 52.9k $6.0m | Reduced -20.7k |
| F/m Investments LLC 0.22% of their portfolio | 52.5k $6.0m | Added +262 |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 48.8k $5.6m | Added +16.6k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 44.6k $5.1m | Added +4.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 41.9k $4.8m | New |
| BARCLAYS PLC 0.00% of their portfolio | 39.0k $4.4m | Added +14.1k |
| Nuveen, LLC 0.00% of their portfolio | 38.6k $4.4m | Reduced -5.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 38.0k $4.3m | Reduced -2.4k |
| ISTHMUS PARTNERS, LLC 0.49% of their portfolio | 37.3k $4.2m | Reduced -402 |
| Swiss National Bank 0.00% of their portfolio | 36.8k $4.2m | Added +200 |
| UBS Group AG 0.00% of their portfolio | 33.5k $3.8m | Added +3.1k |
| GW&K Investment Management, LLC 0.03% of their portfolio | 33.4k $3.8m | Reduced -1.4k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 32.8k $3.7m | Added +5.1k |
| CITIGROUP INC 0.00% of their portfolio | 29.7k $3.4m | Reduced -16 |
| WOODSTOCK CORP 0.31% of their portfolio | 29.5k $3.4m | Added +100 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 29.1k $3.3m | Added +6.3k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 28.4k $3.2m | Reduced -12.6k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 27.4k $3.1m | Added +769 |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 26.9k $3.1m | Reduced -100 |
| FMR LLC 0.00% of their portfolio | 26.2k $3.0m | Added +1.3k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 23.0k $2.6m | Added +781 |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 22.8k $2.6m | Added +1.7k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 21.4k $2.4m | Added +1.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 20.7k $2.4m | Unchanged |
| MARTINGALE ASSET MANAGEMENT L P 0.06% of their portfolio | 20.2k $2.3m | Added +1.1k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 20.1k $2.3m | Reduced -40 |
| Acuitas Investments, LLC 1.80% of their portfolio | 19.9k $2.3m | Reduced -7.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 19.1k $2.2m | Added +294 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 18.9k $2.1m | Added +12.8k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 18.1k $2.1m | Added +13.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 18.0k $2.0m | Added +1.7k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 17.8k $2.0m | Added +90 |
| Linden Thomas Advisory Services, LLC 0.21% of their portfolio | 16.8k $1.9m | Reduced -167 |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 15.6k $1.8m | Added +3.8k |
| CAPSTONE INVESTMENT ADVISORS, LLC 0.01% of their portfolio | 15.4k $1.7m | New |
| Jackson Creek Investment Advisors LLC 0.44% of their portfolio | 14.5k $1.6m | Added +2.1k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 14.2k $1.6m | Reduced -196 |
| Verition Fund Management LLC 0.01% of their portfolio | 14.2k $1.6m | New |
| NORGES BANK 0.00% of their portfolio | 14.1k $1.6m | Reduced -9.0k |
| CenterBook Partners LP 0.09% of their portfolio | 13.5k $1.5m | Reduced -54.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 13.2k $1.5m | Added +436 |
| Baird Financial Group, Inc. 0.00% of their portfolio | 13.1k $1.5m | Added +1.5k |
| NFJ INVESTMENT GROUP, LLC 0.05% of their portfolio | 12.8k $1.5m | Reduced -80 |
| Calamos Advisors LLC 0.01% of their portfolio | 12.2k $1.4m | Reduced -7.7k |
| Legato Capital Management LLC 0.16% of their portfolio | 11.6k $1.3m | Reduced -8.0k |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 11.5k $1.3m | Added +1.0k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 11.4k $1.3m | Added +1.1k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 11.2k $1.3m | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 11.1k $1.3m | Reduced -204 |
| Lisanti Capital Growth, LLC 0.34% of their portfolio | 10.7k $1.2m | Reduced -41.9k |