LIGAND PHARMACEUTICALS INC LGND
COM NEW · Common Stock · CUSIP 53220K504
Biopharmaceutical company based out of La Jolla, California
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- Founded1987
- Websiteligand.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.0m this quarter). Holder counts are more reliable. Shares outstanding: 16.9m as of 2022-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $66.82. Options: 6 managers hold calls ($1.7m notional), 3 hold puts ($173.7k).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 204 |
| Q4 2022 | 197 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $22.6m | $852.0k | 0.04 |
| Q4 2022 | $1.7m | $173.7k | 0.10 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +131.0k |
| BlackRock Inc. | Added | +124.1k |
| Pacer Advisors, Inc. | New | +112.1k |
| MORGAN STANLEY | Added | +64.1k |
| MARSHALL WACE, LLP | Added | +53.0k |
| D. E. Shaw & Co., Inc. | New | +51.3k |
| VANGUARD GROUP INC | Added | +49.7k |
| MILLENNIUM MANAGEMENT LLC | Added | +43.4k |
| Cubist Systematic Strategies, LLC | Added | +41.2k |
| SG Americas Securities, LLC | New | +37.8k |
Biggest sellers
| JANUS HENDERSON GROUP PLC | Reduced | -1.3m |
| STATE STREET CORP | Reduced | -301.4k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | Reduced | -275.9k |
| Chicago Capital, LLC | Reduced | -140.3k |
| Aberdeen Group plc | Reduced | -133.4k |
| Stonepine Capital Management, LLC | Sold out | -99.6k |
| Orchard Capital Management, LLC | Sold out | -75.5k |
| Rafferty Asset Management, LLC | Sold out | -36.3k |
| CITIGROUP INC | Reduced | -29.4k |
| INVESTMENT MANAGEMENT OF VIRGINIA LLC | Sold out | -28.7k |
Biggest calls
| GROUP ONE TRADING LLC | Unchanged | $668.0k10.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $607.9k9.1k shares |
| CITADEL ADVISORS LLC | Reduced | $454.2k6.8k shares |
| Walleye Capital LLC | Unchanged | $6.7k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Reduced | $0200 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $160.3k2.4k shares |
| Walleye Capital LLC | Reduced | $13.4k200 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -1.1 pts · filed 2025-10-17 | 14.5% |
| Invesco Ltd. 13G · institution new · filed 2026-08-13 | 6.1% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.6% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.2 pts · filed 2025-11-14 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 3 | $3.1m | — |
| Q1 2022 | 0 | — | 1 | $93.2k | — |
| Q2 2022 | 1 | $206.9k | 0 | — | — |
| Q3 2022 | 0 | — | 1 | $88.1k | — |
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-12-16 | HIGGINS JOHN L Director | Sold | $618.7k10.0k shares |
| 2022-11-17 | HIGGINS JOHN L Chief Executive Officer, director | Sold | $783.2k10.0k shares |
| 2022-11-09 | Espinoza Octavio Chief Financial Officer | Sold | $128.3k1.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.01% of their portfolio | 2.8m $186.4m | Added +124.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.8m $123.1m | Added +49.7k |
| JANUS HENDERSON GROUP PLC 0.06% of their portfolio | 1.3m $83.9m | Reduced -1.3m |
| MACQUARIE GROUP LTD 0.06% of their portfolio | 800.6k $53.5m | Added +7.0k |
| STATE STREET CORP 0.00% of their portfolio | 649.9k $43.4m | Reduced -301.4k |
| VILLERE ST DENIS J & CO LLC 2.52% of their portfolio | 483.3k $32.3m | Reduced -7.8k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 457.9k $30.6m | Added +8.8k |
| Stephens Investment Management Group LLC 0.56% of their portfolio | 454.4k $30.7m | Added +2.7k |
| Chicago Capital, LLC 1.18% of their portfolio | 319.1k $21.3m | Reduced -140.3k |
| Aberdeen Group plc 0.06% of their portfolio | 309.0k $20.6m | Reduced -133.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 300.7k $20.1m | Added +10.6k |
| RICE HALL JAMES & ASSOCIATES, LLC 1.09% of their portfolio | 285.6k $19.1m | Reduced -11.0k |
| Impax Asset Management Group plc 0.07% of their portfolio | 234.3k $15.7m | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 226.9k $15.2m | Added +35.8k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 209.6k $14.0m | Added +43.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 203.3k $13.6m | Added +30.2k |
| MORGAN STANLEY 0.00% of their portfolio | 184.6k $12.3m | Added +64.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 168.6k $11.3m | Added +8.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 156.8k $10.5m | Reduced -5.7k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 152.9k $10.2m | Added +131.0k |
| NORGES BANK 0.00% of their portfolio | 145.1k $9.7m | Added +17.8k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.04% of their portfolio | 141.1k $9.4m | Reduced -275.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 135.1k $9.0m | Reduced -8.9k |
| Knott David M Jr 2.94% of their portfolio | 115.0k $7.7m | Unchanged |
| Man Group plc 0.03% of their portfolio | 113.1k $7.6m | Added +11.3k |
| Pacer Advisors, Inc. 0.04% of their portfolio | 112.1k $7.5m | New |
| KORNITZER CAPITAL MANAGEMENT INC /KS 0.14% of their portfolio | 106.8k $7.1m | Reduced -18.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 103.6k $6.9m | Added +1.2k |
| MARSHALL WACE, LLP 0.02% of their portfolio | 92.9k $6.2m | Added +53.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 74.3k $5.0m | Reduced -23.6k |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 73.9k $4.9m | Added +3.9k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 68.1k $4.5m | Added +25.0k |
| Smith, Graham & Co., Investment Advisors, LP 0.53% of their portfolio | 65.4k $4.4m | Reduced -20.5k |
| Monarch Partners Asset Management LLC 1.23% of their portfolio | 62.3k $4.2m | Added +2.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 61.7k $4.1m | Added +26.0k |
| WOODSTOCK CORP 0.49% of their portfolio | 55.0k $3.7m | Reduced -6.7k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 51.3k $3.4m | New |
| Cubist Systematic Strategies, LLC 0.03% of their portfolio | 51.2k $3.4m | Added +41.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 50.7k $3.4m | Added +2.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 50.5k $3.4m | Added +1.9k |
| Legal & General Group Plc 0.00% of their portfolio | 46.7k $3.1m | Added +1.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 45.0k $3.0m | Reduced -6.9k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 40.8k $2.7m | Added +36.9k |
| Swiss National Bank 0.00% of their portfolio | 40.7k $2.7m | Added +700 |
| Fisher Asset Management, LLC 0.00% of their portfolio | 39.7k $2.6m | Added +11.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 38.8k $2.6m | Reduced -1.3k |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 37.9k $2.5m | Added +28.9k |
| SG Americas Securities, LLC 0.04% of their portfolio | 37.8k $2.5m | New |
| BARCLAYS PLC 0.00% of their portfolio | 37.3k $2.5m | First filing |
| HRT FINANCIAL LP 0.03% of their portfolio | 31.4k $2.1m | Added +18.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 31.1k $2.1m | Added +2.5k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 30.5k $2.0m | Added +322 |
| GW&K Investment Management, LLC 0.02% of their portfolio | 30.1k $2.0m | Reduced -310 |
| Public Sector Pension Investment Board 0.02% of their portfolio | 29.2k $2.0m | Reduced -202 |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 29.0k $1.9m | Added +26.3k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 28.1k $1.9m | Unchanged |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 27.6k $1.8m | Added +27.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 25.3k $1.7m | Added +16 |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 24.5k $1.6m | Added +7.8k |
| Trexquant Investment LP 0.04% of their portfolio | 23.5k $1.6m | Added +7.8k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 23.5k $1.6m | Added +1.4k |
| AMI ASSET MANAGEMENT CORP 0.10% of their portfolio | 20.9k $1.4m | Reduced -7.4k |
| GSA CAPITAL PARTNERS LLP 0.17% of their portfolio | 20.8k $1.4m | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 20.7k $1.4m | Added +246 |
| ClariVest Asset Management LLC 0.07% of their portfolio | 20.5k $1.4m | Reduced -65 |
| ISTHMUS PARTNERS, LLC 0.20% of their portfolio | 19.8k $1.3m | Reduced -59 |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 19.6k $1.3m | Reduced -946 |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 18.3k $1.2m | Added +2.0k |
| ExodusPoint Capital Management, LP 0.02% of their portfolio | 18.1k $1.2m | Added +12.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 17.6k $1.2m | Unchanged |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.01% of their portfolio | 17.2k $1.1m | Added +2.6k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 16.5k $1.1m | Reduced -117 |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 16.4k $1.1m | Reduced -535 |
| Calamos Advisors LLC 0.01% of their portfolio | 15.9k $1.1m | New |
| Court Place Advisors, LLC 0.38% of their portfolio | 15.5k $1.0m | Unchanged |
| Engineers Gate Manager LP 0.06% of their portfolio | 14.4k $958.6k | Added +11.8k |
| Cornerstone Capital, Inc. 0.12% of their portfolio | 13.7k $913.2k | Reduced -1.8k |
| Candriam S.C.A. 0.01% of their portfolio | 13.5k $904.8k | New |
| CITIGROUP INC 0.00% of their portfolio | 13.0k $866.3k | Reduced -29.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 12.8k $856.3k | Reduced -2.9k |
| Jump Financial, LLC 0.04% of their portfolio | 12.6k $844.2k | New |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.00% of their portfolio | 12.6k $843.5k | New |
| Aquatic Capital Management LLC 0.06% of their portfolio | 11.7k $781.0k | Added +2.9k |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 11.7k $780.0k | Unchanged |
| Capula Management Ltd 0.08% of their portfolio | 11.6k $777.6k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 11.5k $768.2k | Added +8.9k |
| Walleye Capital LLC 0.02% of their portfolio | 11.4k $762.7k | Added +7.8k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 11.2k $751.3k | Reduced -13 |
| MIRABELLA FINANCIAL SERVICES LLP 0.07% of their portfolio | 11.2k $750.4k | New |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 11.2k $746.0k | Added +70 |
| STRS OHIO 0.00% of their portfolio | 11.0k $734.0k | Added +3.5k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 10.8k $721.4k | Reduced -137 |
| TEXAS PERMANENT SCHOOL FUND CORP 0.01% of their portfolio | 10.8k $721.0k | Reduced -749 |
| YOUSIF CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 10.3k $688.9k | Reduced -3.4k |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 10.2k $683.4k | Unchanged |
| ALGERT GLOBAL LLC 0.04% of their portfolio | 10.2k $682.2k | New |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 10.0k $670.0k | Unchanged |
| TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio | 9.9k $664.0k | New |
| Ergoteles LLC 0.02% of their portfolio | 9.9k $659.7k | Added +3.9k |
| DUALITY ADVISERS, LP 0.07% of their portfolio | 9.8k $655.9k | New |