LENZ THERAPEUTICS INC LENZ
COM · Common Stock · CUSIP 52635N103
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSolana Beach, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($895.1k this quarter). Holder counts are more reliable. Shares outstanding: 28.5m as of 2025-07-24, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $29.32. Options: 5 managers hold calls ($11.5m notional), 2 hold puts ($304.8k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2024 | 57 |
| Q2 2024 | 66 |
| Q3 2024 | 79 |
| Q4 2024 | 96 |
| Q1 2025 | 106 |
| Q2 2025 | 115 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 43 | 16 |
| Q3 2024 | 41 | 25 |
| Q4 2024 | 53 | 29 |
| Q1 2025 | 53 | 39 |
| Q2 2025 | 79 | 31 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $0 | $0 | — |
| Q4 2024 | $0 | $0 | — |
| Q1 2025 | $0 | $0 | — |
| Q2 2025 | $11.5m | $304.8k | 0.03 |
Biggest buyers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +585.0k |
| MORGAN STANLEY | Added | +396.6k |
| Ally Bridge Group (NY) LLC | New | +343.3k |
| Saturn V Capital Management LP | New | +342.3k |
| Invesco Ltd. | New | +266.7k |
| BlackRock, Inc. | Added | +265.9k |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | New | +240.0k |
| UBS Group AG | Added | +214.3k |
| Paradigm Biocapital Advisors LP | Added | +205.1k |
| STEMPOINT CAPITAL LP | New | +183.9k |
Biggest sellers
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -292.0k |
| Point72 Asset Management, L.P. | Reduced | -234.1k |
| SAMSARA BIOCAPITAL, LLC | Reduced | -183.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | Sold out | -42.2k |
| BBR PARTNERS, LLC | Sold out | -40.0k |
| TD Asset Management Inc | Sold out | -34.8k |
| ExodusPoint Capital Management, LP | Sold out | -27.8k |
| Verition Fund Management LLC | Sold out | -27.6k |
| GOLDMAN SACHS GROUP INC | Sold out | -22.9k |
| Squarepoint Ops LLC | Reduced | -18.0k |
Biggest calls
| Caption Management, LLC | New | $5.1m175.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $5.1m174.5k shares |
| JANE STREET GROUP, LLC | New | $1.2m40.1k shares |
| SIMPLEX TRADING, LLC | New | $55.0k1.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $304.8k10.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence -1.5 pts · filed 2025-11-07 | 13.6% |
| BlackRock, Inc. 13G · institution +0.9 pts · filed 2026-04-27 | 5.8% |
| FMR LLC 13G · institution -6.1 pts · filed 2026-09-08 | 5.7% |
| BlackRock Portfolio Management LLC 13G · institution new · filed 2026-10-27 | 5.2% |
| Squarepoint Ops LLC 13G · passive investor new · filed 2026-04-08 | 5.1% |
Fell to 5% or below in the last year: MILLENNIUM MANAGEMENT LLC (3.7%, 2026-10-21), Ridgeback Capital Investments L.P. (0.0%, 2026-02-17), Point72 Asset Management, L.P. (4.8%, 2025-11-14), Paradigm Biocapital Advisors LP (3.8%, 2025-11-14)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 1 | $15.0m | 0 | — | — |
| Q2 2024 | 2 | $551.0k | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-27 | Versant Venture Capital VI, L.P. +8 10% owner | Sold | $6.1m200.0k shares |
| 2025-06-20 | Versant Venture Capital VI, L.P. +8 10% owner | Sold | $4.1m133.9k shares |
| 2025-06-20 | Versant Venture Capital VI, L.P. +8 10% owner · See footnote | Sold | $3.1m100.9k shares |
| 2025-06-18 | Versant Venture Capital VI, L.P. +8 10% owner · See footnote | Sold | $3.0m100.0k shares |
| 2025-06-10 | Versant Venture Capital VI, L.P. +8 10% owner · See footnote | Sold | $10.2m350.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 2.06% of their portfolio | 4.2m $122.5m | Unchanged |
| Alpha Wave Global, LP 11.41% of their portfolio | 3.6m $105.9m | Unchanged |
| Paradigm Biocapital Advisors LP 2.15% of their portfolio | 1.7m $50.3m | Added +205.1k |
| BlackRock, Inc. 0.00% of their portfolio | 1.4m $42.0m | Added +265.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.3m $37.8m | Added +91.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.06% of their portfolio | 1.1m $32.9m | Added +585.0k |
| 72 Investment Holdings, LLC 77.84% of their portfolio | 1.0m $29.8m | Unchanged |
| SECTORAL ASSET MANAGEMENT INC 18.91% of their portfolio | 977.2k $28.6m | Unchanged |
| TANG CAPITAL MANAGEMENT LLC 1.33% of their portfolio | 897.6k $26.3m | Added +130.7k |
| UBS Group AG 0.01% of their portfolio | 881.5k $25.8m | Added +214.3k |
| RTW INVESTMENTS, LP 0.36% of their portfolio | 863.4k $25.3m | Unchanged |
| Point72 Asset Management, L.P. 0.04% of their portfolio | 618.1k $18.1m | Reduced -234.1k |
| MORGAN STANLEY 0.00% of their portfolio | 585.4k $17.2m | Added +396.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 416.1k $12.2m | Added +55.7k |
| STATE STREET CORP 0.00% of their portfolio | 375.7k $11.0m | Added +88.4k |
| Ally Bridge Group (NY) LLC 8.80% of their portfolio | 343.3k $10.1m | New |
| SAMSARA BIOCAPITAL, LLC 2.06% of their portfolio | 343.0k $10.1m | Reduced -183.4k |
| Saturn V Capital Management LP 4.07% of their portfolio | 342.3k $10.0m | New |
| Invesco Ltd. 0.00% of their portfolio | 266.7k $7.8m | New |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 0.27% of their portfolio | 240.0k $7.0m | New |
| Alyeska Investment Group, L.P. 0.02% of their portfolio | 217.1k $6.4m | Added +75.0k |
| SCOGGIN MANAGEMENT LP 2.71% of their portfolio | 200.0k $5.9m | Added +100.0k |
| STEMPOINT CAPITAL LP 1.74% of their portfolio | 183.9k $5.4m | New |
| Granahan Investment Management, LLC 0.22% of their portfolio | 183.3k $5.4m | Added +7.1k |
| Nuveen, LLC 0.00% of their portfolio | 178.2k $5.2m | Added +111.2k |
| Candriam S.C.A. 0.03% of their portfolio | 171.3k $5.0m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 170.7k $5.0m | Added +29.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 142.1k $4.2m | Added +18.1k |
| LORD, ABBETT & CO. LLC 0.01% of their portfolio | 131.7k $3.9m | Added +82.1k |
| Skandinaviska Enskilda Banken AB (publ) 0.01% of their portfolio | 93.3k $2.7m | New |
| Rock Springs Capital Management LP 0.15% of their portfolio | 84.0k $2.5m | Added +900 |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 83.3k $2.7m | Added +125 |
| Knott David M Jr 1.09% of their portfolio | 82.0k $2.4m | New |
| FMR LLC 0.00% of their portfolio | 81.6k $2.4m | Added +500 |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 77.3k $2.3m | Unchanged |
| Aberdeen Group plc 0.00% of their portfolio | 74.3k $2.2m | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 68.0k $2.0m | Added +49.7k |
| DEBUSSY CAPITAL MANAGEMENT LP 0.26% of their portfolio | 59.3k $1.7m | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 54.3k $1.6m | Added +53.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 53.9k $1.6m | Reduced -12.1k |
| HARBOR CAPITAL ADVISORS, INC. 0.06% of their portfolio | 50.0k $1.5m | Added +1.4k |
| BARCLAYS PLC 0.00% of their portfolio | 45.8k $1.3m | Added +21.4k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 44.2k $1.3m | Added +44.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 44.0k $1.3m | Added +15.3k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 40.9k $1.2m | Reduced -895 |
| Sovran Advisors, LLC 0.13% of their portfolio | 40.4k $1.3m | New |
| Lisanti Capital Growth, LLC 0.29% of their portfolio | 36.2k $1.1m | Added +10.5k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 36.0k $1.1m | Added +18.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 34.8k $1.0m | Added +4.3k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 30.1k $882.5k | Reduced -296 |
| KESTRA PRIVATE WEALTH SERVICES, LLC 0.01% of their portfolio | 27.3k $800.3k | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 25.2k $737.3k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 24.4k $714.1k | Added +6.4k |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 22.3k $654.0k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 22.2k $650.2k | Added +5.9k |
| Swiss National Bank 0.00% of their portfolio | 21.3k $624.3k | Unchanged |
| Delta Investment Management, LLC 0.11% of their portfolio | 19.9k $582.5k | Reduced -4.1k |
| Calamos Advisors LLC 0.00% of their portfolio | 17.6k $514.8k | New |
| KELLEHER FINANCIAL ADVISORS 0.17% of their portfolio | 17.0k $498.9k | Unchanged |
| Rinkey Investments 0.13% of their portfolio | 15.2k $445.1k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 15.1k $442.8k | Added +5.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 14.9k $438.0k | Reduced -292.0k |
| Creative Planning 0.00% of their portfolio | 14.1k $412.3k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 13.3k $389.4k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 11.9k $347.7k | Added +2.4k |
| Legal & General Group Plc 0.00% of their portfolio | 11.0k $322.1k | Added +2.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 10.9k $320.7k | Added +3.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 10.4k $303.7k | Added +2.3k |
| AlphaQuest LLC 0.03% of their portfolio | 10.2k $299.5k | Added +3.7k |
| Squarepoint Ops LLC 0.00% of their portfolio | 10.0k $292.3k | Reduced -18.0k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 9.7k $285.7k | Added +2.2k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 9.6k $280.2k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 9.4k $275.5k | Added +200 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 9.3k $273.3k | Added +1.7k |
| Legato Capital Management LLC 0.03% of their portfolio | 9.3k $272.6k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 9.3k $271.1k | Added +380 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 9.0k $264.9k | Reduced -557 |
| CITIGROUP INC 0.00% of their portfolio | 8.9k $261.7k | Reduced -781 |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 8.6k $251.0k | Reduced -8 |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 7.0k $206.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 6.9k $202.0k | Added +3.4k |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 5.7k $165.7k | Added +137 |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 4.1k $121.0k | Added +1.6k |
| Virtus Investment Advisers, LLC 0.03% of their portfolio | 3.2k $93.2k | Reduced -2.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 2.0k $57.2k | Added +944 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 1.8k $53.3k | Added +586 |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 1.6k $46.9k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.4k $41.2k | Added +477 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 1.2k $34.2k | Added +1.1k |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 1.1k $33.6k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 1.1k $31.9k | Added +139 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 704 $20.6k | Unchanged |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 599 $17.6k | Added +597 |
| AMALGAMATED BANK 0.00% of their portfolio | 434 $13.0k | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 396 $11.6k | Reduced -64 |
| GAMMA Investing LLC 0.00% of their portfolio | 287 $8.4k | Added +60 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 244 $7.2k | Added +211 |
| GPS Wealth Strategies Group, LLC 0.00% of their portfolio | 179 $5.2k | New |
| CWM, LLC 0.00% of their portfolio | 174 $5.0k | Added +90 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 172 $5.0k | New |