LENZ THERAPEUTICS INC LENZ
COM · Common Stock · CUSIP 52635N103
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSolana Beach, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($101.6k this quarter). Holder counts are more reliable. Shares outstanding: 27.5m as of 2024-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $28.86. Options: 1 managers hold calls ($0 notional), 1 hold puts ($0).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2024 | 57 |
| Q2 2024 | 66 |
| Q3 2024 | 79 |
| Q4 2024 | 96 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 43 | 16 |
| Q3 2024 | 41 | 25 |
| Q4 2024 | 53 | 29 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $0 | $1.3m | — |
| Q2 2024 | $0 | $0 | — |
| Q3 2024 | $0 | $0 | — |
| Q4 2024 | $0 | $0 | — |
Biggest buyers
| Paradigm Biocapital Advisors LP | New | +770.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +374.3k |
| BlackRock, Inc. | Added | +225.6k |
| STATE STREET CORP | Added | +205.2k |
| UBS Group AG | Added | +79.8k |
| TD Asset Management Inc | Added | +74.7k |
| VANGUARD GROUP INC | Added | +59.6k |
| Granahan Investment Management, LLC | New | +51.8k |
| HARBOR CAPITAL ADVISORS, INC. | New | +44.0k |
| MORGAN STANLEY | Added | +41.8k |
Biggest sellers
| EcoR1 Capital, LLC | Sold out | -346.8k |
| SAMSARA BIOCAPITAL, LLC | Reduced | -221.5k |
| Parkman Healthcare Partners LLC | Sold out | -139.4k |
| Schonfeld Strategic Advisors LLC | Sold out | -107.3k |
| Point72 Asset Management, L.P. | Reduced | -81.0k |
| Ikarian Capital, LLC | Reduced | -55.0k |
| BML Capital Management, LLC | Reduced | -50.7k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -23.9k |
| AMERIPRISE FINANCIAL INC | Reduced | -16.9k |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | -14.6k |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence -1.5 pts · filed 2025-11-07 | 13.6% |
| BlackRock, Inc. 13G · institution +0.9 pts · filed 2026-04-27 | 5.8% |
| FMR LLC 13G · institution -6.1 pts · filed 2026-09-08 | 5.7% |
| BlackRock Portfolio Management LLC 13G · institution new · filed 2026-10-27 | 5.2% |
| Squarepoint Ops LLC 13G · passive investor new · filed 2026-04-08 | 5.1% |
Fell to 5% or below in the last year: MILLENNIUM MANAGEMENT LLC (3.7%, 2026-10-21), Ridgeback Capital Investments L.P. (0.0%, 2026-02-17), Point72 Asset Management, L.P. (4.8%, 2025-11-14), Paradigm Biocapital Advisors LP (3.8%, 2025-11-14)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 1 | $15.0m | 0 | — | — |
| Q2 2024 | 2 | $551.0k | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
None reported in Q4 2024.
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 1.61% of their portfolio | 4.2m $120.6m | Unchanged |
| Alpha Wave Global, LP 48.29% of their portfolio | 3.6m $104.3m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.2m $34.0m | Added +59.6k |
| BlackRock, Inc. 0.00% of their portfolio | 1.2m $33.4m | Added +225.6k |
| 72 Investment Holdings, LLC 59.83% of their portfolio | 1.0m $29.4m | Unchanged |
| SAMSARA BIOCAPITAL, LLC 3.91% of their portfolio | 987.0k $28.5m | Reduced -221.5k |
| SECTORAL ASSET MANAGEMENT INC 18.83% of their portfolio | 977.2k $28.2m | Unchanged |
| RTW INVESTMENTS, LP 0.38% of their portfolio | 863.4k $24.9m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 823.0k $23.8m | Added +374.3k |
| Point72 Asset Management, L.P. 0.06% of their portfolio | 783.9k $22.6m | Reduced -81.0k |
| Paradigm Biocapital Advisors LP 0.77% of their portfolio | 770.5k $22.2m | New |
| TANG CAPITAL MANAGEMENT LLC 1.47% of their portfolio | 766.9k $22.1m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 494.3k $14.3m | Added +205.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 334.0k $9.6m | Reduced -4.0k |
| Ikarian Capital, LLC 1.23% of their portfolio | 149.5k $4.3m | Reduced -55.0k |
| Alyeska Investment Group, L.P. 0.02% of their portfolio | 142.1k $4.1m | Added +20.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 139.3k $4.0m | Added +9.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 127.2k $3.7m | Added +3.8k |
| TD Asset Management Inc 0.00% of their portfolio | 103.0k $3.0m | Added +74.7k |
| MORGAN STANLEY 0.00% of their portfolio | 92.3k $2.7m | Added +41.8k |
| UBS Group AG 0.00% of their portfolio | 85.9k $2.5m | Added +79.8k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 83.1k $2.4m | Added +35 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 67.9k $2.0m | Added +36.6k |
| DEBUSSY CAPITAL MANAGEMENT LP 0.21% of their portfolio | 56.3k $1.4m | Reduced -2.5k |
| Granahan Investment Management, LLC 0.06% of their portfolio | 51.8k $1.5m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 49.8k $1.4m | Added +16.7k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 48.1k $1.4m | Reduced -16.9k |
| HARBOR CAPITAL ADVISORS, INC. 0.06% of their portfolio | 44.0k $1.3m | New |
| BBR PARTNERS, LLC 0.08% of their portfolio | 40.0k $1.2m | Unchanged |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 39.7k $1.1m | Reduced -14.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 38.2k $1.1m | Added +18.4k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 34.0k $983.4k | Reduced -154 |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 32.5k $938.4k | Added +8.6k |
| BARCLAYS PLC 0.00% of their portfolio | 30.1k $867.7k | Added +13.6k |
| Rock Springs Capital Management LP 0.03% of their portfolio | 29.3k $846.0k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 29.2k $843.4k | Reduced -428 |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 28.2k $814.6k | Added +3.6k |
| KESTRA PRIVATE WEALTH SERVICES, LLC 0.01% of their portfolio | 27.3k $788.3k | Reduced -200 |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 25.4k $732.3k | Reduced -23.9k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 23.1k $667.8k | Unchanged |
| Delta Investment Management, LLC 0.11% of their portfolio | 19.2k $555.5k | New |
| Swiss National Bank 0.00% of their portfolio | 18.9k $545.6k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 18.8k $541.4k | Added +1.1k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 17.7k $511.5k | New |
| CITIGROUP INC 0.00% of their portfolio | 17.5k $503.9k | Added +8.3k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 17.1k $493.1k | Reduced -8.4k |
| KELLEHER FINANCIAL ADVISORS 0.19% of their portfolio | 17.0k $491.5k | Reduced -3.8k |
| Rinkey Investments 0.14% of their portfolio | 15.2k $438.4k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 9.7k $280.7k | Added +4.4k |
| BML Capital Management, LLC 0.17% of their portfolio | 9.3k $267.7k | Reduced -50.7k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 9.2k $265.6k | Added +8.3k |
| Legal & General Group Plc 0.00% of their portfolio | 8.7k $252.4k | Added +7.7k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 8.5k $245.0k | First filing |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 8.4k $242.0k | Reduced -2.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 8.3k $240.8k | Reduced -3.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 8.0k $231.4k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 7.9k $229.2k | Reduced -4.1k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 7.9k $229.3k | Added +1.0k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 7.7k $221.5k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 7.6k $219.0k | Reduced -1.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 7.5k $216.6k | Added +1.6k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 7.4k $215.0k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 7.4k $215.0k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 6.2k $180.3k | Reduced -471 |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 5.8k $168.3k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 5.5k $158.0k | Added +935 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 3.5k $100.8k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 2.5k $72.9k | First filing |
| VIRTUS ADVISERS, LLC 0.03% of their portfolio | 2.3k $66.7k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.9k $53.7k | Added +1.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.8k $51.6k | Reduced -859 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.7k $50.0k | Added +440 |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 1.6k $46.2k | First filing |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 1.2k $35.5k | Unchanged |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 1.1k $30.2k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 916 $28.7k | New |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 577 $16.7k | First filing |
| Sterling Capital Management LLC 0.00% of their portfolio | 402 $11.6k | Added +362 |
| Aster Capital Management (DIFC) Ltd 0.00% of their portfolio | 278 $8.0k | New |
| FMR LLC 0.00% of their portfolio | 212 $6.1k | Added +78 |
| AMALGAMATED BANK 0.00% of their portfolio | 135 $4.0k | Unchanged |
| US BANCORP \DE\ 0.00% of their portfolio | 116 $3.3k | New |
| GAMMA Investing LLC 0.00% of their portfolio | 109 $3.1k | Added +27 |
| CoreCap Advisors, LLC 0.00% of their portfolio | 101 $2.9k | New |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 91 $3.0k | New |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 45 $1.3k | New |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 34 $982 | Added +12 |
| CWM, LLC 0.00% of their portfolio | 34 $1.0k | Added +8 |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 28 $808 | Unchanged |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 12 $346 | New |
| Smartleaf Asset Management LLC 0.00% of their portfolio | 11 $330 | Unchanged |
| Fortitude Family Office, LLC 0.00% of their portfolio | 9 $260 | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 4 $115 | Reduced -9 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 2 $57 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |
| IFP Advisors, Inc 0.00% of their portfolio | 0 $29 | New |