KYVERNA THERAPEUTICS INC KYTX
COM · Common Stock · CUSIP 501976104
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersEmeryville, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($173.3k this quarter). Holder counts are more reliable. Shares outstanding: 43.2m as of 2024-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.92. Options: 2 managers hold calls ($6.8k notional), 2 hold puts ($67.5k).
Trends to Q3 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2024 | 91 |
| Q2 2024 | 89 |
| Q3 2024 | 95 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 60 | 42 |
| Q3 2024 | 50 | 43 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2023 | $0 | $0 | — |
| Q1 2024 | $5.0k | $514.2k | 103.50 |
| Q2 2024 | $48.2k | $102.0k | 2.11 |
| Q3 2024 | $6.8k | $67.5k | 9.86 |
Biggest buyers
| JPMORGAN CHASE & CO | Added | +652.2k |
| MILLENNIUM MANAGEMENT LLC | Added | +330.5k |
| MBB PUBLIC MARKETS I LLC | Added | +204.3k |
| Integral Health Asset Management, LLC | New | +200.0k |
| FRANKLIN RESOURCES INC | Added | +113.9k |
| NOVO HOLDINGS A/S | Added | +100.0k |
| NORTHERN TRUST CORP | Added | +93.4k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +70.7k |
| Cubist Systematic Strategies, LLC | New | +69.0k |
| Hudson Bay Capital Management LP | New | +52.0k |
Biggest sellers
| RTW INVESTMENTS, LP | Sold out | -1.9m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Reduced | -1.1m |
| Casdin Capital, LLC | Sold out | -575.0k |
| GREAT POINT PARTNERS LLC | Sold out | -499.2k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -478.3k |
| Artal Group S.A. | Sold out | -200.0k |
| Walleye Capital LLC | Sold out | -156.5k |
| NORGES BANK | Reduced | -140.6k |
| Woodline Partners LP | Reduced | -90.4k |
| CITADEL ADVISORS LLC | Reduced | -90.4k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $6.8k1.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $67.5k13.8k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Westlake BioPartners Fund I, L.P. 13G · exempt (held before listing) filed 2026-02-06 | 7.8% |
| GordonMD Global Investments LP 13G · passive investor new · filed 2025-11-17 | 7.0% |
| Northpond Ventures III, LP 13G · passive investor filed 2026-02-17 | 6.1% |
| HIRSCHMAN ORIN 13G · institution new · filed 2026-10-19 | 5.9% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-29 | 5.1% |
Fell to 5% or below in the last year: Bain Capital Life Sciences Opportunities III, LP (4.8%, 2026-08-14)
Insider purchases and sales in Q3 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q3 2024.
Holders, Q3 2024
| Manager | Shares | Change |
|---|---|---|
| JPMORGAN CHASE & CO 0.00% of their portfolio | 4.8m $23.3m | Added +652.2k |
| Vida Ventures Advisors, LLC 15.96% of their portfolio | 4.5m $22.1m | Unchanged |
| Bain Capital Life Sciences Investors, LLC 1.71% of their portfolio | 3.4m $16.5m | Unchanged |
| Northpond Ventures, LLC 36.46% of their portfolio | 3.3m $15.9m | Unchanged |
| NOVO HOLDINGS A/S 0.45% of their portfolio | 1.9m $9.0m | Added +100.0k |
| BlackRock, Inc. 0.00% of their portfolio | 1.5m $7.4m | First filing |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.3m $6.1m | Added +330.5k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.0m $4.9m | Reduced -9.9k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 937.0k $5.3m | Added +113.9k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.07% of their portfolio | 918.9k $4.5m | Reduced -1.1m |
| Insight Holdings Group, LLC 0.19% of their portfolio | 912.9k $4.5m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 628.2k $3.1m | Reduced -41.3k |
| MBB PUBLIC MARKETS I LLC 0.25% of their portfolio | 614.5k $3.0m | Added +204.3k |
| EcoR1 Capital, LLC 0.08% of their portfolio | 450.0k $2.2m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 443.3k $2.2m | Added +70.7k |
| STATE STREET CORP 0.00% of their portfolio | 326.2k $1.6m | Added +10.2k |
| SPHERA FUNDS MANAGEMENT LTD. 0.20% of their portfolio | 248.7k $1.2m | Added +12.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 235.1k $1.1m | Reduced -478.3k |
| Integral Health Asset Management, LLC 0.12% of their portfolio | 200.0k $978.0k | New |
| E Fund Management Co., Ltd. 0.05% of their portfolio | 189.4k $926.3k | Unchanged |
| Rock Springs Capital Management LP 0.03% of their portfolio | 179.0k $875.1k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 166.6k $814.8k | Added +41.6k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 153.8k $752.0k | Added +41.1k |
| PERCEPTIVE ADVISORS LLC 0.02% of their portfolio | 150.0k $733.5k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 137.7k $673.5k | Reduced -90.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 133.9k $655.0k | Added +93.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 122.9k $600.8k | Reduced -33.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 122.8k $600.4k | Added +4.8k |
| Affinity Asset Advisors, LLC 0.09% of their portfolio | 119.9k $586.3k | Reduced -80.1k |
| MORGAN STANLEY 0.00% of their portfolio | 119.8k $585.8k | Added +511 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 101.9k $498.3k | Reduced -13.5k |
| TD Asset Management Inc 0.00% of their portfolio | 90.2k $472.0k | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 79.8k $390.2k | Added +17.5k |
| BARCLAYS PLC 0.00% of their portfolio | 70.2k $343.1k | Added +12.4k |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 69.0k $337.2k | New |
| XTX Topco Ltd 0.02% of their portfolio | 52.8k $258.2k | Reduced -30.5k |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 52.0k $254.5k | New |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 45.0k $220.1k | Reduced -45.0k |
| Verition Fund Management LLC 0.00% of their portfolio | 44.6k $218.2k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 43.3k $211.6k | Reduced -12.5k |
| Woodline Partners LP 0.00% of their portfolio | 42.5k $207.7k | Reduced -90.4k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 42.0k $205.0k | New |
| NORGES BANK 0.00% of their portfolio | 40.0k $195.6k | Reduced -140.6k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 39.6k $193.5k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 39.2k $191.7k | Added +17.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 37.8k $184.8k | Unchanged |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 34.5k $168.6k | New |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 33.3k $162.9k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 33.1k $161.6k | Reduced -573 |
| MARSHALL WACE, LLP 0.00% of their portfolio | 32.2k $157.6k | Added +21.8k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 32.0k $156.5k | Added +16.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 30.0k $146.7k | Added +4.3k |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.02% of their portfolio | 27.6k $134.9k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 27.2k $133.0k | Added +26.0k |
| Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio | 26.2k $128.1k | Unchanged |
| DISCOVERY CAPITAL MANAGEMENT, LLC / CT 0.01% of their portfolio | 25.0k $122.2k | Unchanged |
| CAXTON CORP 0.47% of their portfolio | 23.0k $112.4k | Unchanged |
| SECTORAL ASSET MANAGEMENT INC 0.07% of their portfolio | 22.9k $112.0k | Added +15.9k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 22.8k $111.7k | Unchanged |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 21.4k $104.6k | New |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 19.9k $97.2k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 19.8k $96.7k | Reduced -240 |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 16.9k $82.6k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 15.4k $75.2k | Reduced -9.8k |
| CITIGROUP INC 0.00% of their portfolio | 13.5k $66.0k | Added +8.3k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 12.8k $62.8k | New |
| Creative Planning 0.00% of their portfolio | 11.0k $53.9k | New |
| TWINBEECH CAPITAL LP 0.00% of their portfolio | 10.2k $49.8k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 9.3k $45.5k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 9.0k $44.0k | Reduced -56 |
| UBS Group AG 0.00% of their portfolio | 8.2k $40.1k | Reduced -1.4k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 7.5k $181.0k | Unchanged |
| FMR LLC 0.00% of their portfolio | 6.7k $32.7k | New |
| VIRTUS ADVISERS, LLC 0.01% of their portfolio | 6.4k $31.2k | Added +112 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 4.5k $22.0k | Reduced -9.1k |
| STRS OHIO 0.00% of their portfolio | 3.1k $15.2k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 2.2k $10.7k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 2.1k $10.0k | Added +477 |
| Legal & General Group Plc 0.00% of their portfolio | 1.7k $8.4k | Reduced -5.7k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 1.6k $8.1k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 1.2k $6.0k | Reduced -13.8k |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 1.2k $5.9k | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 968 $4.7k | New |
| nVerses Capital, LLC 0.00% of their portfolio | 600 $2.9k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 582 $3.0k | Unchanged |
| SIGNATUREFD, LLC 0.00% of their portfolio | 314 $1.5k | New |
| Lindbrook Capital, LLC 0.00% of their portfolio | 182 $890 | New |
| US BANCORP \DE\ 0.00% of their portfolio | 169 $826 | New |
| COMERICA BANK 0.00% of their portfolio | 122 $597 | Reduced -30 |
| Washington Trust Advisors, Inc. 0.00% of their portfolio | 60 $294 | Unchanged |
| CWM, LLC 0.00% of their portfolio | 55 $0 | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 32 $156 | First filing |
| Allworth Financial LP 0.00% of their portfolio | 28 $137 | New |
| EARNED WEALTH ADVISORS, LLC 0.00% of their portfolio | 8 $39 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |