Vault-13

IONIS PHARMACEUTICALS INC IONS

COM · Common Stock · CUSIP 462222100 · ISIN US4622221004

American pharmaceutical company

497 institutional holders +3 vs Q4 2025
172,232,387172.2m shares reported held*
104.2% of all shares outstanding*
$12.9bnreported value*
63 new 178 added 158 reduced 65 sold out net sold ≈ $242.3m (-3.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($29.7m this quarter). Holder counts are more reliable. Shares outstanding: 165.3m as of 2026-04-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $75.12. Options: 21 managers hold calls ($141.4m notional), 17 hold puts ($144.3m).

Trends to Q1 2026

Institutional holders

Managers reporting a position, each quarter

0200400600Q3 22: 350Q4 22: 339Q1 23: 316Q2 23: 307Q3 23: 313Q4 23: 366Q1 24: 362Q2 24: 358Q3 24: 357Q4 24: 359Q1 25: 348Q2 25: 366Q3 25: 439Q4 25: 494Q1 26: 497497Q3 22Q3 23Q3 24Q3 25Q1 26
Numbers
QuarterHolders
Q3 2022350
Q4 2022339
Q1 2023316
Q2 2023307
Q3 2023313
Q4 2023366
Q1 2024362
Q2 2024358
Q3 2024357
Q4 2024359
Q1 2025348
Q2 2025366
Q3 2025439
Q4 2025494
Q1 2026497

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q2 24: 168 bought or addedQ2 24: 182 cut or sold outQ3 24: 176 bought or addedQ3 24: 159 cut or sold outQ3 24Q4 24: 160 bought or addedQ4 24: 169 cut or sold outQ1 25: 150 bought or addedQ1 25: 184 cut or sold outQ1 25Q2 25: 197 bought or addedQ2 25: 169 cut or sold outQ3 25: 245 bought or addedQ3 25: 152 cut or sold outQ3 25Q4 25: 261 bought or addedQ4 25: 186 cut or sold outQ1 26: 241 bought or addedQ1 26: 223 cut or sold outQ1 26
Numbers
QuarterBought or addedCut or sold out
Q2 2024168182
Q3 2024176159
Q4 2024160169
Q1 2025150184
Q2 2025197169
Q3 2025245152
Q4 2025261186
Q1 2026241223

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ2 25 calls: $65.2mQ2 25 puts: $34.9mQ2 25P/C 0.54Q3 25 calls: $171.8mQ3 25 puts: $74.8mQ3 25P/C 0.44Q4 25 calls: $149.5mQ4 25 puts: $102.3mQ4 25P/C 0.68Q1 26 calls: $141.4mQ1 26 puts: $144.3mQ1 26P/C 1.02
Numbers
QuarterCallsPutsP/C
Q2 2025$65.2m$34.9m0.54
Q3 2025$171.8m$74.8m0.44
Q4 2025$149.5m$102.3m0.68
Q1 2026$141.4m$144.3m1.02

Biggest buyers

Capital World Investors Added +3,225,070+3.2m
TWO SIGMA INVESTMENTS, LP Added +3,198,983+3.2m
ROYAL BANK OF CANADA Added +2,683,018+2.7m
MILLENNIUM MANAGEMENT LLC Added +958,244+958.2k
Artisan Partners Limited Partnership Added +876,892+876.9k
GOLDMAN SACHS GROUP INC Added +843,881+843.9k
GEODE CAPITAL MANAGEMENT, LLC Added +835,483+835.5k
PERCEPTIVE ADVISORS LLC New +504,000+504.0k
FMR LLC Added +484,536+484.5k
NEUBERGER BERMAN GROUP LLC Added +335,228+335.2k

Biggest sellers

T. Rowe Price Investment Management, Inc. Reduced -8,738,855-8.7m
TWO SIGMA ADVISERS, LP Sold out -3,052,111-3.1m
Bellevue Group AG Reduced -2,983,534-3.0m
CITADEL ADVISORS LLC Reduced -1,192,102-1.2m
NOMURA HOLDINGS INC Reduced -734,735-734.7k
Tri Locum Partners LP Sold out -557,174-557.2k
BARCLAYS PLC Reduced -552,997-553.0k
Polar Capital Holdings Plc Reduced -503,913-503.9k
BNP PARIBAS ASSET MANAGEMENT Holding S.A. Reduced -445,304-445.3k
Amundi Reduced -436,989-437.0k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $56.8m755.8k shares
JANE STREET GROUP, LLC Added $21.7m288.7k shares
JPMORGAN CHASE & CO New $12.0m165.0k shares
CITADEL ADVISORS LLC Added $8.7m115.3k shares
Ikarian Capital, LLC Added $8.4m112.1k shares
CITIGROUP INC Added $7.4m98.4k shares
NOMURA HOLDINGS INC Reduced $4.5m59.4k shares
SIG BROKERAGE, LP New $4.1m55.0k shares
IMC-Chicago, LLC Added $3.8m50.8k shares
BOOTHBAY FUND MANAGEMENT, LLC Added $2.4m31.6k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $34.1m454.3k shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC Added $33.8m450.0k shares
JANE STREET GROUP, LLC Added $21.0m279.8k shares
CITADEL ADVISORS LLC Added $18.6m248.3k shares
JPMORGAN CHASE & CO New $12.0m165.0k shares
SIMPLEX TRADING, LLC Reduced $4.8m63.9k shares
LMR Partners LLP Added $3.9m51.4k shares
BARCLAYS PLC Reduced $3.8m50.0k shares
WOLVERINE ASSET MANAGEMENT LLC Unchanged $2.6m35.0k shares
SIG BROKERAGE, LP New $2.3m30.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Capital World Investors 13G · institution +1.7 pts · filed 2026-05-14 12.8% +1.7 pts 21.2m≈ $1.7bn 2026-05-14
BlackRock, Inc. 13G · institution filed 2025-04-17 5.7% 9.1m≈ $718.9m 2025-04-17
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.0% new 8.3m≈ $661.7m 2026-04-30

Fell to 5% or below in the last year: T. Rowe Price Investment Management, Inc. (3.7%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)

Insider purchases and sales in Q1 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
20020Q2 24: 0 buyingQ2 24: 4 sellingQ3 24: 0 buyingQ3 24: 3 sellingQ3 24Q4 24: 1 buyingQ4 24: 3 sellingQ1 25: 0 buyingQ1 25: 10 sellingQ1 25Q2 25: 1 buyingQ2 25: 3 sellingQ3 25: 0 buyingQ3 25: 14 sellingQ3 25Q4 25: 0 buyingQ4 25: 12 sellingQ1 26: 0 buyingQ1 26: 15 sellingQ1 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20240—4$1.1m$900.9k
Q3 20240—3$829.8k$829.8k
Q4 20241$181.1k3$811.0k$809.0k
Q1 20250—10$5.2m$1.5m
Q2 20251$477.9k3$216.4k—
Q3 20250—14$42.6m$29.3m
Q4 20250—12$26.8m$23.7m
Q1 20260—15$75.8m$57.6m
DateInsiderTradeSharesPrice ValueTheir holding
2026-03-19 Schneider Eugene EVP, Chf Clinical Develop Ofcr Sold plan 5,812 $70.97 $412.5k5.8k shares -8%
2026-03-17 HOUGEN ELIZABETH L EVP, Finance & CFO Sold plan 10,172 $73.21 $744.7k10.2k shares -11%
2026-03-16 HOUGEN ELIZABETH L EVP, Finance & CFO Sold plan 215,048 $72.40 $15.6m215.0k shares -70%
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Sold plan 37,277 $75.85 $2.8m37.3k shares -76%
2026-03-10 Monia Brett P Chief Executive Officer, director Sold plan 34,103 $75.92 $2.6m34.1k shares -12%
2026-03-09 Monia Brett P Chief Executive Officer, director Sold plan 126,670 $75.20 $9.5m126.7k shares -34%
2026-03-09 O'NEIL PATRICK R. EVP CLO & General Counsel Sold plan 10,148 $75.25 $763.6k10.1k shares -14%
2026-03-04 Baroldi Joseph EVP, Chief Business Officer · by Spouse Sold plan 238 $80.00 $19.0k238 shares -5%
2026-03-04 Baroldi Joseph EVP, Chief Business Officer Sold plan 201 $80.00 $16.1k201 shares -4%
2026-03-04 LOSCALZO JOSEPH Director Sold plan 200 $80.00 $16.0k200 shares -0%
2026-03-03 BENNETT C FRANK EVP, Chief Scientific Officer Sold plan 85,089 $79.23 $6.7m85.1k shares -51%
2026-03-03 Diaz Allene M. Director Sold plan 54,878 $79.35 $4.4m54.9k shares -94%
2026-03-03 KLEIN JOSEPH III Director Sold plan 21,332 $79.51 $1.7m21.3k shares -66%
2026-03-03 Devers Shannon L. EVP, Chief Human Resources Ofc Sold plan 20,106 $79.40 $1.6m20.1k shares -47%
2026-03-03 Baroldi Joseph EVP, Chief Business Officer Sold plan 4,096 $79.36 $325.1k4.1k shares -9%
2026-03-03 Baroldi Joseph EVP, Chief Business Officer · by Spouse Sold plan 2,124 $80.42 $170.8k2.1k shares -33%
2026-03-03 LOSCALZO JOSEPH Director Sold plan 832 $80.33 $66.8k832 shares -2%
2026-02-13 Swayze Eric EVP Research Sold plan 15,642 $81.76 $1.3m15.6k shares -33%
2026-02-11 PARSHALL B LYNNE Director Sold plan 5,000 $82.72 $413.6k5.0k shares -8%
2026-02-06 Monia Brett P Chief Executive Officer, director Sold plan 29,430 $85.79 $2.5m29.4k shares -10%
2026-01-30 Monia Brett P Chief Executive Officer, director Sold 62,970 $82.72 $5.2m63.0k shares -18%
2026-01-30 HOUGEN ELIZABETH L EVP, Finance & CFO Sold 6,988 $83.24 $581.7k7.0k shares -5%
2026-01-30 O'NEIL PATRICK R. EVP CLO & General Counsel Sold 6,179 $83.53 $516.1k6.2k shares -8%
2026-01-30 Schneider Eugene EVP, Chf Clinical Develop Ofcr Sold 6,179 $83.45 $515.6k6.2k shares -8%
2026-01-30 Birchler Brian EVP, Corp and Development Ops Sold 6,179 $83.03 $513.0k6.2k shares -8%
2026-01-30 Swayze Eric EVP Research Sold 6,179 $82.93 $512.4k6.2k shares -12%
2026-01-30 BENNETT C FRANK EVP, Chief Scientific Officer Sold 5,885 $82.95 $488.2k5.9k shares -6%
2026-01-30 Baroldi Joseph EVP, Chief Business Officer Sold 5,296 $82.96 $439.4k5.3k shares -10%
2026-01-22 Devers Shannon L. EVP, Chief Human Resources Ofc Sold plan 3,977 $81.34 $323.5k4.0k shares -15%
2026-01-16 Monia Brett P Chief Executive Officer, director Sold 44,034 $74.82 $3.3m44.0k shares -16%

The latest 30 of 44 trades.

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q1 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.10% of their portfolio BOSTON, MA 24,556,63724.6m $1.8bn $1.8bn 0.10% Added +484.5k +484,536
2 Capital World Investors 0.22% of their portfolio LOS ANGELES, CA 21,186,36921.2m $1.6bn $1.6bn 0.22% Added +3.2m +3,225,070
3 BlackRock, Inc. 0.01% of their portfolio New York, NY 10,442,47610.4m $784.1m $784.1m 0.01% Reduced -205.4k -205,387
4 VANGUARD PORTFOLIO MANAGEMENT LLC 0.03% of their portfolio MALVERN, PA 7,808,9027.8m $586.4m $586.4m 0.03% First filing
5 VANGUARD CAPITAL MANAGEMENT LLC 0.01% of their portfolio MALVERN, PA 7,118,3307.1m $534.5m $534.5m 0.01% First filing
6 WELLINGTON MANAGEMENT GROUP LLP 0.09% of their portfolio Boston, MA 6,391,8166.4m $480.0m $480.0m 0.09% Added +131.5k +131,491
7 T. Rowe Price Investment Management, Inc. 0.32% of their portfolio BALTIMORE, MD 6,159,0276.2m $462.5m $462.5m 0.32% Reduced -8.7m -8,738,855
8 TWO SIGMA INVESTMENTS, LP 0.37% of their portfolio NEW YORK, NY 5,857,6295.9m $439.8m $439.8m 0.37% Added +3.2m +3,198,983
9 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 3,995,5644.0m $300.0m $300.0m 0.01% Added +20.7k +20,699
10 GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio BOSTON, MA 3,984,3324.0m $305.2m $305.2m 0.02% Added +835.5k +835,483
11 ROYAL BANK OF CANADA 0.05% of their portfolio TORONTO, A6 3,801,8153.8m $285.5m $285.5m 0.05% Added +2.7m +2,683,018
12 PRICE T ROWE ASSOCIATES INC /MD/ 0.03% of their portfolio BALTIMORE, MD 3,025,2513.0m $227.2m $227.2m 0.03% Added +37.4k +37,411
13 JPMORGAN CHASE & CO 0.01% of their portfolio NEW YORK, NY 2,363,5672.4m $171.4m $171.4m 0.01% Added +58.8k +58,775
14 Tweedy, Browne Co LLC 13.57% of their portfolio Stamford, CT 2,275,6252.3m $170.9m $170.9m 13.57% Reduced -189.3k -189,305
15 Artisan Partners Limited Partnership 0.25% of their portfolio Milwaukee, WI 2,058,3082.1m $154.6m $154.6m 0.25% Added +876.9k +876,892
16 BAKER BROS. ADVISORS LP 0.88% of their portfolio NEW YORK, NY 2,047,7272.0m $153.8m $153.8m 0.88% Added +255.9k +255,886
17 DEERFIELD MANAGEMENT COMPANY, L.P. 1.75% of their portfolio New York, NY 1,979,6692.0m $148.7m $148.7m 1.75% Unchanged
18 Deep Track Capital, LP 3.02% of their portfolio GREENWICH, CT 1,950,0001.9m $146.4m $146.4m 3.02% Added +250.0k +250,000
19 Bellevue Group AG 3.25% of their portfolio ZURICH, V8 1,818,6651.8m $136.6m $136.6m 3.25% Reduced -3.0m -2,983,534
20 GOLDMAN SACHS GROUP INC 0.02% of their portfolio NEW YORK, NY 1,699,8471.7m $127.6m $127.6m 0.02% Added +843.9k +843,881
21 AMERICAN CENTURY COMPANIES INC 0.06% of their portfolio KANSAS CITY, MO 1,663,8031.7m $124.9m $124.9m 0.06% Added +46.7k +46,697
22 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio SAN FRANCISCO, CA 1,583,2661.6m $118.9m $118.9m 0.02% Added +41.4k +41,425
23 FRANKLIN RESOURCES INC 0.03% of their portfolio San Mateo, CA 1,575,0231.6m $118.3m $118.3m 0.03% Added +253.7k +253,678
24 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio NEW YORK, NY 1,475,6321.5m $110.8m $110.8m 0.02% Added +87.1k +87,065
25 Pictet Asset Management Holding SA 0.11% of their portfolio CAROUGE, V8 1,434,9951.4m $107.1m $107.1m 0.11% Added +16.5k +16,504
26 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 4.88% of their portfolio Boston, MA 1,404,0331.4m $105.4m $105.4m 4.88% Reduced -58.7k -58,673
27 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 1,277,3581.3m $95.9m $95.9m 0.01% Added +8.1k +8,068
28 MILLENNIUM MANAGEMENT LLC 0.06% of their portfolio NEW YORK, NY 1,051,5061.1m $79.0m $79.0m 0.06% Added +958.2k +958,244
29 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,026,5091.0m $77.1m $77.1m 0.00% Added +6.6k +6,603
30 VANGUARD FIDUCIARY TRUST CO 0.02% of their portfolio MALVERN, PA 1,024,3771.0m $76.9m $76.9m 0.02% First filing
31 CITADEL ADVISORS LLC 0.05% of their portfolio MIAMI, FL 942,534942.5k $70.8m $70.8m 0.05% Reduced -1.2m -1,192,102
32 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.08% of their portfolio Paris, I0 907,533907.5k $68.1m $68.1m 0.08% Reduced -445.3k -445,304
33 Connor, Clark & Lunn Investment Management Ltd. 0.15% of their portfolio VANCOUVER, A1 874,089874.1k $65.6m $65.6m 0.15% Reduced -202.3k -202,281
34 NORTHERN TRUST CORP 0.01% of their portfolio CHICAGO, IL 868,179868.2k $65.2m $65.2m 0.01% Added +21.5k +21,461
35 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 840,598840.6k $63.1m $63.1m 0.00% Added +57.0k +57,019
36 Polar Capital Holdings Plc 0.27% of their portfolio London, X0 829,511829.5k $62.3m $62.3m 0.27% Reduced -503.9k -503,913
37 GROUPAMA ASSET MANAGMENT 0.90% of their portfolio PARIS, I0 824,540824.5k $61.9m $61.9m 0.90% Added +57.7k +57,651
38 UBS Group AG 0.01% of their portfolio ZURICH, V8 808,443808.4k $60.7m $60.7m 0.01% Reduced -236.6k -236,598
39 NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.10% of their portfolio PHILADELPHIA, PA 785,281785.3k $59.0m $59.0m 0.10% Reduced -79.6k -79,611
40 GW&K Investment Management, LLC 0.52% of their portfolio BOSTON, MA 779,349779.3k $58.5m $58.5m 0.52% Reduced -7.3k -7,319
41 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.03% of their portfolio BOSTON, MA 737,859737.9k $55.4m $55.4m 0.03% Reduced -325.5k -325,468
42 Squarepoint Ops LLC 0.11% of their portfolio NEW YORK, NY 695,276695.3k $52.2m $52.2m 0.11% Added +259.0k +258,997
43 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.20% of their portfolio JUPITER, FL 672,858672.9k $50.5m $50.5m 0.20% Added +87.9k +87,888
44 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.02% of their portfolio Boston, MA 666,116666.1k $50.0m $50.0m 0.02% Reduced -146.6k -146,631
45 AMERIPRISE FINANCIAL INC 0.01% of their portfolio MINNEAPOLIS, MN 660,144660.1k $49.6m $49.6m 0.01% Added +61.4k +61,396
46 Nuveen, LLC 0.01% of their portfolio CHARLOTTE, NC 648,496648.5k $48.7m $48.7m 0.01% Reduced -12.3k -12,273
47 Eversept Partners, LP 3.13% of their portfolio NEW YORK, NY 632,100632.1k $47.5m $47.5m 3.13% Added +93.9k +93,882
48 EVENTIDE ASSET MANAGEMENT, LLC 0.71% of their portfolio Boston, MA 575,000575.0k $43.2m $43.2m 0.71% Unchanged
49 TD Asset Management Inc 0.03% of their portfolio Toronto, A6 529,954530.0k $39.8m $39.8m 0.03% Reduced -243.2k -243,230
50 TEACHER RETIREMENT SYSTEM OF TEXAS 0.16% of their portfolio AUSTIN, TX 523,932523.9k $39.3m $39.3m 0.16% Added +101.0k +101,033
51 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 514,617514.6k $38.6m $38.6m 0.01% Reduced -23.3k -23,269
52 PERCEPTIVE ADVISORS LLC 0.75% of their portfolio NEW YORK, NY 504,000504.0k $37.8m $37.8m 0.75% New
53 BOONE CAPITAL MANAGEMENT LLC 11.51% of their portfolio ATLANTA, GA 500,522500.5k $37.6m $37.6m 11.51% Added +82.7k +82,689
54 Candriam S.C.A. 0.19% of their portfolio STRASSEN, N4 484,053484.1k $36.3m $36.3m 0.19% Reduced -193.6k -193,576
55 BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio PARIS, I0 479,460479.5k $36.0m $36.0m 0.02% Added +144.9k +144,852
56 Alyeska Investment Group, L.P. 0.10% of their portfolio CHICAGO, IL 473,150473.1k $35.5m $35.5m 0.10% Reduced -8.6k -8,561
57 FIRST TRUST ADVISORS LP 0.03% of their portfolio Wheaton, IL 468,363468.4k $35.2m $35.2m 0.03% Reduced -56.9k -56,876
58 NEUBERGER BERMAN GROUP LLC 0.03% of their portfolio NEW YORK, NY 443,272443.3k $33.3m $33.3m 0.03% Added +335.2k +335,228
59 PINNACLE ASSOCIATES LTD 0.42% of their portfolio NEW YORK, NY 436,457436.5k $32.8m $32.8m 0.42% Reduced -25.5k -25,511
60 D. E. Shaw & Co., Inc. 0.03% of their portfolio New York, NY 429,599429.6k $32.3m $32.3m 0.03% Added +96.8k +96,796
61 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 400,669400.7k $31.7m $31.7m 0.01% Added +58.8k +58,820
62 Davern Capital Partners, LP 7.97% of their portfolio NY, NY 386,903386.9k $29.1m $29.1m 7.97% Added +148.4k +148,426
63 C WorldWide Group Holding A/S 0.59% of their portfolio COPENHAGEN, G7 366,000366.0k $27.5m $27.5m 0.59% Unchanged
64 NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio ALBANY, NY 350,414350.4k $26.3m $26.3m 0.04% Added +108.6k +108,561
65 Capital Research Global Investors 0.00% of their portfolio Los Angeles, CA 323,015323.0k $24.3m $24.3m 0.00% New
66 RENAISSANCE TECHNOLOGIES LLC 0.04% of their portfolio NEW YORK, NY 305,549305.5k $22.9m $22.9m 0.04% Added +81.9k +81,942
67 Swiss National Bank 0.01% of their portfolio ZURICH, V8 304,500304.5k $22.9m $22.9m 0.01% Added +6.0k +6,000
68 Hudson Bay Capital Management LP 0.13% of their portfolio STAMFORD, CT 295,100295.1k $22.2m $22.2m 0.13% Reduced -179.9k -179,900
69 Legal & General Group Plc 0.01% of their portfolio London, X0 294,679294.7k $22.1m $22.1m 0.01% Reduced -30.5k -30,469
70 Privium Fund Management B.V. 4.53% of their portfolio AMSTERDAM, P7 290,024290.0k $21.8m $21.8m 4.53% Added +49.2k +49,200
71 BARCLAYS PLC 0.01% of their portfolio LONDON, X0 289,874289.9k $21.8m $21.8m 0.01% Reduced -553.0k -552,997
72 ARK Investment Management LLC 0.17% of their portfolio ST. PETERSBURG, FL 288,716288.7k $21.7m $21.7m 0.17% Reduced -134.3k -134,252
73 TimesSquare Capital Management, LLC 0.35% of their portfolio NEW YORK, NY 275,674275.7k $20.7m $20.7m 0.35% New
74 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 267,215267.2k $20.1m $20.1m 0.00% Added +91.2k +91,180
75 California Public Employees Retirement System 0.01% of their portfolio Sacramento, CA 255,485255.5k $19.2m $19.2m 0.01% Added +42.1k +42,117
76 HRT FINANCIAL LP 0.07% of their portfolio NEW YORK, NY 252,250252.2k $18.9m $18.9m 0.07% Added +229.3k +229,322
77 Zurich Insurance Group Ltd/FI 0.14% of their portfolio ZURICH, V8 239,645239.6k $18.0m $18.0m 0.14% Reduced -22.2k -22,175
78 DAVENPORT & Co LLC 0.10% of their portfolio RICHMOND, VA 238,238238.2k $17.9m $17.9m 0.10% Added +20.3k +20,341
79 J. Goldman & Co LP 0.82% of their portfolio NEW YORK, NY 235,260235.3k $17.7m $17.7m 0.82% Added +167.6k +167,621
80 RAYMOND JAMES FINANCIAL INC 0.01% of their portfolio ST. PETERSBURG, FL 235,121235.1k $17.7m $17.7m 0.01% Reduced -22.1k -22,089
81 ExodusPoint Capital Management, LP 0.17% of their portfolio NEW YORK, NY 227,084227.1k $17.1m $17.1m 0.17% Added +143.2k +143,209
82 Orion Investment Co 5.36% of their portfolio ST. LOUIS, MO 225,015225.0k $16.9m $16.9m 5.36% Reduced -146 -146
83 Universal- Beteiligungs- und Servicegesellschaft mbH 0.03% of their portfolio FRANKFURT AM MAIN, 2M 219,652219.7k $16.5m $16.5m 0.03% Added +78 +78
84 TOCQUEVILLE ASSET MANAGEMENT L.P. 0.24% of their portfolio New York, NY 219,220219.2k $16.5m $16.5m 0.24% Added +15.5k +15,490
85 Handelsbanken Fonder AB 0.05% of their portfolio STOCKHOLM, V7 213,911213.9k $16.1m $16.1m 0.05% Added +166.0k +166,000
86 Trexquant Investment LP 0.12% of their portfolio STAMFORD, CT 213,645213.6k $16.0m $16.0m 0.12% Added +81.4k +81,404
87 Jump Financial, LLC 0.23% of their portfolio Chicago, IL 206,675206.7k $15.5m $15.5m 0.23% New
88 STIFEL FINANCIAL CORP 0.01% of their portfolio ST. LOUIS, MO 196,703196.7k $14.8m $14.8m 0.01% Reduced -2.2k -2,160
89 Corient Private Wealth LP 0.02% of their portfolio MIAMI, FL 196,599196.6k $14.8m $14.8m 0.02% Reduced -234.8k -234,775
90 JANE STREET GROUP, LLC 0.02% of their portfolio NEW YORK, NY 191,818191.8k $14.4m $14.4m 0.02% Added +161.3k +161,347
91 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 189,853189.9k $14.3m $14.3m 0.00% Reduced -90.2k -90,192
92 HSBC HOLDINGS PLC 0.01% of their portfolio LONDON, X0 185,967186.0k $14.0m $14.0m 0.01% Added +132.1k +132,085
93 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio WEST SACRAMENTO, CA 176,485176.5k $13.3m $13.3m 0.01% Added +32.3k +32,312
94 RHUMBLINE ADVISERS 0.01% of their portfolio BOSTON, MA 173,440173.4k $13.0m $13.0m 0.01% Reduced -1.9k -1,947
95 SECTOR GAMMA AS 3.00% of their portfolio OSLO, Q8 169,468169.5k $12.7m $12.7m 3.00% Reduced -15.5k -15,509
96 DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.01% of their portfolio FRANKFURT AM MAIN, 2M 167,657167.7k $12.6m $12.6m 0.01% Unchanged
97 Focus Partners Wealth 0.01% of their portfolio ST LOUIS, MO 165,544165.5k $12.4m $12.4m 0.01% Reduced -16.3k -16,273
98 ADAR1 Capital Management, LLC 0.72% of their portfolio AUSTIN, TX 160,338160.3k $12.0m $12.0m 0.72% Added +13.2k +13,208
99 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 159,891159.9k $12.0m $12.0m 0.00% Added +10.4k +10,448
100 Sicart Associates LLC 3.07% of their portfolio NEW YORK, NY 159,412159.4k $12.0m $12.0m 3.07% Reduced -4.1k -4,145