INTELLIA THERAPEUTICS INC NTLA
COM · Common Stock · CUSIP 45826J105 · ISIN US45826J1051
It is a biotechnology company developing biopharmaceuticals using a CRISPR gene editing system.
- SectorHealth care
- IndustryIn Vitro & In Vivo Diagnostic Substances
- HeadquartersCambridge, MA
- Founded2014
- Websiteintelliatx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($25.3m this quarter). Holder counts are more reliable. Shares outstanding: 107.3m as of 2025-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.38. Options: 14 managers hold calls ($19.6m notional), 12 hold puts ($11.2m).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 321 |
| Q4 2022 | 306 |
| Q1 2023 | 291 |
| Q2 2023 | 293 |
| Q3 2023 | 290 |
| Q4 2023 | 294 |
| Q1 2024 | 285 |
| Q2 2024 | 292 |
| Q3 2024 | 285 |
| Q4 2024 | 295 |
| Q1 2025 | 297 |
| Q2 2025 | 284 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 153 | 103 |
| Q4 2023 | 160 | 117 |
| Q1 2024 | 152 | 130 |
| Q2 2024 | 158 | 125 |
| Q3 2024 | 151 | 132 |
| Q4 2024 | 168 | 116 |
| Q1 2025 | 141 | 139 |
| Q2 2025 | 150 | 141 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $11.0m | $20.9m | 1.91 |
| Q4 2024 | $16.5m | $11.5m | 0.70 |
| Q1 2025 | $7.0m | $6.4m | 0.91 |
| Q2 2025 | $19.6m | $11.2m | 0.57 |
Biggest buyers
| BAKER BROS. ADVISORS LP | Added | +2.0m |
| Woodline Partners LP | Added | +1.2m |
| ROYAL BANK OF CANADA | Added | +980.6k |
| D. E. Shaw & Co., Inc. | Added | +792.3k |
| RENAISSANCE TECHNOLOGIES LLC | New | +676.9k |
| Marex Group Ltd | New | +623.6k |
| Trexquant Investment LP | Added | +522.6k |
| Granahan Investment Management, LLC | Added | +437.7k |
| JPMORGAN CHASE & CO | Added | +396.9k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Added | +382.4k |
Biggest sellers
| Capital International Investors | Sold out | -3.8m |
| CITADEL ADVISORS LLC | Reduced | -2.0m |
| Casdin Capital, LLC | Sold out | -2.0m |
| BlackRock, Inc. | Reduced | -529.0k |
| BANK OF AMERICA CORP /DE/ | Reduced | -516.4k |
| STATE STREET CORP | Reduced | -471.0k |
| Contrarius Group Holdings Ltd | Reduced | -468.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -365.9k |
| Discovery Value Fund | Reduced | -332.9k |
| PDT Partners, LLC | Reduced | -263.7k |
Biggest calls
| PEAK6 LLC | Added | $2.9m308.8k shares |
| Walleye Capital LLC | Added | $2.9m307.2k shares |
| CAPITAL FUND MANAGEMENT S.A. | Added | $2.5m268.7k shares |
| UBS Group AG | New | $2.3m240.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.2m229.8k shares |
| CITADEL ADVISORS LLC | Added | $1.8m186.8k shares |
| GROUP ONE TRADING LLC | Added | $1.6m173.7k shares |
| Walleye Trading LLC | Added | $1.5m155.0k shares |
| SIMPLEX TRADING, LLC | Added | $1.2m128.6k shares |
| Caption Management, LLC | Unchanged | $328.3k35.0k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $2.3m241.1k shares |
| Walleye Capital LLC | Added | $2.0m216.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.5m157.7k shares |
| Walleye Trading LLC | Added | $1.2m130.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.2m123.9k shares |
| CAPITAL FUND MANAGEMENT S.A. | New | $783.2k83.5k shares |
| GROUP ONE TRADING LLC | Added | $767.3k81.8k shares |
| JANE STREET GROUP, LLC | Reduced | $590.9k63.0k shares |
| NOMURA HOLDINGS INC | Unchanged | $375.2k40.0k shares |
| Caption Management, LLC | Unchanged | $328.3k35.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution +1.2 pts · filed 2026-02-03 | 12.3% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 8.2% |
| STATE STREET CORP 13G · institution +1.3 pts · filed 2026-08-07 | 6.8% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), GOLDMAN SACHS GROUP INC (2.7%, 2026-02-12), Contrarius Investment Management Ltd (0.6%, 2026-02-11)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 2 | $99.2k | $84.6k |
| Q4 2023 | 0 | — | 1 | $6.3k | $6.3k |
| Q1 2024 | 0 | — | 7 | $1.6m | $65.7k |
| Q2 2024 | 0 | — | 1 | $37.6k | $37.6k |
| Q3 2024 | 0 | — | 1 | $9.3k | — |
| Q4 2024 | 0 | — | 1 | $38.2k | — |
| Q1 2025 | 0 | — | 8 | $863.1k | $2.6k |
| Q2 2025 | 0 | — | 2 | $17.0k | $17.0k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-30 | GOODMAN JESSE Director | Sold plan | $14.8k1.5k shares |
| 2025-04-29 | Bhanji Muna Director | Sold plan | $2.3k265 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| ARK Investment Management LLC 0.90% of their portfolio | 13.0m $122.1m | Added +6.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 10.9m $101.8m | Added +100.1k |
| BlackRock, Inc. 0.00% of their portfolio | 10.0m $94.1m | Reduced -529.0k |
| MORGAN STANLEY 0.00% of their portfolio | 4.1m $38.6m | Added +315.2k |
| STATE STREET CORP 0.00% of their portfolio | 4.0m $37.9m | Reduced -471.0k |
| REGENERON PHARMACEUTICALS, INC. 2.34% of their portfolio | 3.7m $34.7m | Unchanged |
| BAKER BROS. ADVISORS LP 0.24% of their portfolio | 2.7m $25.1m | Added +2.0m |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 2.7m $25.1m | Reduced -154.1k |
| Amova Asset Management Americas, Inc. 0.25% of their portfolio | 2.7m $25.0m | Reduced -154.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.6m $24.4m | Added +126.0k |
| TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio | 2.3m $21.4m | Added +283.7k |
| TWO SIGMA ADVISERS, LP 0.04% of their portfolio | 2.1m $19.6m | Added +110.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.0m $19.2m | Reduced -365.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.9m $17.5m | Reduced -101.9k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio | 1.6m $14.6m | Added +37.6k |
| Contrarius Group Holdings Ltd 0.82% of their portfolio | 1.6m $14.6m | Reduced -468.5k |
| FMR LLC 0.00% of their portfolio | 1.5m $14.3m | Reduced -69.8k |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 1.3m $12.3m | Reduced -203.6k |
| Woodline Partners LP 0.06% of their portfolio | 1.2m $11.4m | Added +1.2m |
| Trexquant Investment LP 0.12% of their portfolio | 1.1m $10.6m | Added +522.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.0m $9.5m | Added +980.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 940.5k $8.8m | Added +396.9k |
| Granahan Investment Management, LLC 0.35% of their portfolio | 913.6k $8.6m | Added +437.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 909.0k $8.5m | Reduced -8.8k |
| UBS Group AG 0.00% of their portfolio | 880.9k $8.3m | Reduced -245.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 856.5k $8.0m | Added +76.3k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 831.0k $7.8m | Added +244.5k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 824.7k $7.7m | Added +792.3k |
| STIFEL FINANCIAL CORP 0.01% of their portfolio | 785.0k $7.4m | Reduced -4.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 764.0k $7.2m | Added +334.9k |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. 0.53% of their portfolio | 729.4k $6.8m | Reduced -23.3k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 710.0k $6.7m | Reduced -2.0m |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 676.9k $6.3m | New |
| ARMISTICE CAPITAL, LLC 0.23% of their portfolio | 650.0k $6.1m | Added +286.0k |
| Vestmark Advisory Solutions, Inc. 0.09% of their portfolio | 638.3k $6.0m | Added +326.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 637.9k $6.0m | Added +116.2k |
| Marex Group Ltd 0.11% of their portfolio | 623.6k $5.8m | New |
| BARCLAYS PLC 0.00% of their portfolio | 518.1k $4.9m | Added +278.1k |
| Hudson Bay Capital Management LP 0.03% of their portfolio | 465.0k $4.4m | Reduced -100.0k |
| Jump Financial, LLC 0.05% of their portfolio | 456.6k $4.3m | Reduced -47.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 429.1k $4.0m | Reduced -516.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 426.7k $4.0m | Added +86.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 409.9k $3.8m | Reduced -61.8k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 406.4k $3.8m | Added +382.4k |
| CAPITAL FUND MANAGEMENT S.A. 0.04% of their portfolio | 371.6k $3.5m | Added +235.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 311.2k $2.9m | Added +29.2k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 298.7k $2.8m | Added +49.5k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.25% of their portfolio | 294.4k $2.8m | Added +188.2k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 275.7k $2.6m | Added +137.8k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 267.1k $2.5m | Reduced -149.0k |
| Invesco Ltd. 0.00% of their portfolio | 251.6k $2.4m | Added +80.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 238.4k $2.2m | Reduced -119.1k |
| Nuveen, LLC 0.00% of their portfolio | 237.4k $2.2m | Reduced -34.9k |
| Graham Capital Management, L.P. 0.07% of their portfolio | 234.8k $2.2m | New |
| Avidity Partners Management LP 0.44% of their portfolio | 232.0k $2.2m | New |
| Discovery Value Fund 4.16% of their portfolio | 228.7k $2.1m | Reduced -332.9k |
| HRT FINANCIAL LP 0.01% of their portfolio | 221.3k $2.1m | Added +133.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 212.8k $2.0m | Added +64.8k |
| PDT Partners, LLC 0.10% of their portfolio | 196.6k $1.8m | Reduced -263.7k |
| Swiss National Bank 0.00% of their portfolio | 187.4k $1.8m | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.12% of their portfolio | 184.4k $1.7m | Reduced -35.5k |
| PINNACLE ASSOCIATES LTD 0.02% of their portfolio | 169.3k $1.6m | Reduced -45.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 164.2k $1.5m | Added +7.4k |
| GROUP ONE TRADING LLC 0.05% of their portfolio | 161.2k $1.5m | Added +144.2k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.04% of their portfolio | 156.2k $1.5m | Unchanged |
| Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio | 153.2k $1.4m | Added +6.7k |
| CITIGROUP INC 0.00% of their portfolio | 144.8k $1.4m | Reduced -152.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 142.9k $1.3m | Reduced -108.7k |
| TWINBEECH CAPITAL LP 0.03% of their portfolio | 137.8k $1.3m | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 136.5k $1.3m | Added +45.7k |
| Engineers Gate Manager LP 0.02% of their portfolio | 133.0k $1.2m | Added +8.4k |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 132.6k $1.2m | Added +109.3k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 129.5k $1.2m | Reduced -88.1k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 128.8k $1.2m | Reduced -51.3k |
| SPHERA FUNDS MANAGEMENT LTD. 0.32% of their portfolio | 128.8k $1.2m | Reduced -252.3k |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 115.0k $1.1m | Added +46.7k |
| Verition Fund Management LLC 0.01% of their portfolio | 108.6k $1.0m | Reduced -162.8k |
| Legal & General Group Plc 0.00% of their portfolio | 107.5k $1.0m | Added +3.6k |
| OPPENHEIMER & CO INC 0.01% of their portfolio | 106.2k $996.3k | Added +87.5k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 103.1k $967.1k | Unchanged |
| Generali Investments Towarzystwo Funduszy Inwestycyjnych 0.49% of their portfolio | 100.0k $938.0k | Added +19.0k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 92.4k $866.0k | Reduced -15.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 89.6k $840.7k | Reduced -1.0k |
| Intellectus Partners, LLC 0.17% of their portfolio | 86.0k $806.4k | Added +3.1k |
| Erste Asset Management GmbH 0.01% of their portfolio | 85.1k $813.6k | Added +63.0k |
| Orchard Capital Management, LLC 0.82% of their portfolio | 79.2k $743.0k | Reduced -106.3k |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 76.8k $720.0k | Reduced -64.5k |
| Aptus Capital Advisors, LLC 0.01% of their portfolio | 75.2k $705.6k | Reduced -13.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 75.0k $757.0k | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 69.4k $651.1k | Reduced -3.7k |
| Elmwood Wealth Management, Inc. 0.25% of their portfolio | 67.9k $637.1k | Added +135 |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 67.2k $630.0k | Added +24.9k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 65.0k $609.7k | Unchanged |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 64.2k $603.0k | Unchanged |
| LPL Financial LLC 0.00% of their portfolio | 64.0k $599.9k | Added +9.2k |
| BENJAMIN EDWARDS INC 0.01% of their portfolio | 63.0k $591.3k | Added +1.1k |
| Second Line Capital, LLC 0.14% of their portfolio | 63.0k $591.2k | Reduced -16.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 61.0k $571.9k | Added +2.4k |
| Birchview Capital, LP 0.56% of their portfolio | 60.0k $562.8k | New |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 58.6k $550.0k | Reduced -29.0k |