INNOVIVA INC INVA
COM · Common Stock · CUSIP 45781M101 · ISIN US45781M1018
Company in Burlingame, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBurlingame, CA
- Founded1996
- Websiteinvestor.inva.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($6.0m this quarter). Holder counts are more reliable. Shares outstanding: 74.1m as of 2026-02-13, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $19.98. Options: 3 managers hold calls ($727.6k notional), 1 hold puts ($24.0k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 213 |
| Q4 2022 | 208 |
| Q1 2023 | 194 |
| Q2 2023 | 199 |
| Q3 2023 | 194 |
| Q4 2023 | 198 |
| Q1 2024 | 217 |
| Q2 2024 | 214 |
| Q3 2024 | 222 |
| Q4 2024 | 237 |
| Q1 2025 | 248 |
| Q2 2025 | 267 |
| Q3 2025 | 263 |
| Q4 2025 | 280 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 105 | 87 |
| Q2 2024 | 102 | 107 |
| Q3 2024 | 94 | 100 |
| Q4 2024 | 124 | 83 |
| Q1 2025 | 118 | 111 |
| Q2 2025 | 149 | 103 |
| Q3 2025 | 137 | 119 |
| Q4 2025 | 140 | 118 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $43.5k | $44.5k | 1.02 |
| Q2 2025 | $206.9k | $3.2m | 15.68 |
| Q3 2025 | $240.9k | $2.9m | 11.83 |
| Q4 2025 | $727.6k | $24.0k | 0.03 |
Biggest buyers
| BlackRock, Inc. | Added | +1.2m |
| VANGUARD GROUP INC | Added | +819.8k |
| HSBC HOLDINGS PLC | New | +647.3k |
| ROYCE & ASSOCIATES LP | Added | +414.4k |
| TWO SIGMA INVESTMENTS, LP | Added | +317.6k |
| BARCLAYS PLC | Added | +253.8k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | Added | +246.4k |
| STATE STREET CORP | Added | +239.8k |
| Qube Research & Technologies Ltd | Added | +192.0k |
| Integrated Wealth Concepts LLC | New | +183.7k |
Biggest sellers
| ROYAL BANK OF CANADA | Reduced | -1.2m |
| FRANKLIN RESOURCES INC | Reduced | -1.1m |
| CITADEL ADVISORS LLC | Reduced | -808.7k |
| Nuveen, LLC | Reduced | -743.8k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -376.8k |
| D. E. Shaw & Co., Inc. | Reduced | -364.3k |
| JPMORGAN CHASE & CO | Reduced | -288.1k |
| MARSHALL WACE, LLP | Reduced | -260.4k |
| JANE STREET GROUP, LLC | Reduced | -222.7k |
| VICTORY CAPITAL MANAGEMENT INC | Reduced | -143.6k |
Biggest calls
| CITADEL ADVISORS LLC | New | $627.7k31.4k shares |
| GROUP ONE TRADING LLC | New | $70.0k3.5k shares |
| SIMPLEX TRADING, LLC | New | $30.0k1.5k shares |
Biggest puts
| SIMPLEX TRADING, LLC | Added | $24.0k1.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-10-27 | 15.4% |
| DIMENSIONAL FUND ADVISORS LP 13G · institution filed 2026-01-21 | 5.8% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.8% |
| RENAISSANCE TECHNOLOGIES LLC 13G · institution -1.9 pts · filed 2026-02-12 | 5.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q4 2025.
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 10.7m $213.4m | Added +1.2m |
| VANGUARD GROUP INC 0.00% of their portfolio | 7.9m $158.3m | Added +819.8k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 4.4m $87.2m | Added +30.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.13% of their portfolio | 4.2m $84.2m | Reduced -376.8k |
| Sarissa Capital Management LP 25.25% of their portfolio | 2.8m $56.3m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 2.8m $55.9m | Added +239.8k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.03% of their portfolio | 2.4m $47.1m | Reduced -898 |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 2.2m $44.8m | Reduced -111.3k |
| SYSTEMATIC FINANCIAL MANAGEMENT LP 1.00% of their portfolio | 2.1m $42.3m | Reduced -1.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $35.0m | Added +178.2k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 1.6m $32.2m | Reduced -31.0k |
| Boston Partners 0.03% of their portfolio | 1.5m $31.0m | Added +116.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.5m $30.4m | Added +42.6k |
| MORGAN STANLEY 0.00% of their portfolio | 1.4m $28.4m | Reduced -6.9k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 1.4m $27.8m | Reduced -1.1m |
| MARSHALL WACE, LLP 0.03% of their portfolio | 1.4m $27.8m | Reduced -260.4k |
| Qube Research & Technologies Ltd 0.03% of their portfolio | 1.2m $24.3m | Added +192.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.1m $22.4m | Reduced -82.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 1.0m $20.4m | Added +147.6k |
| ROYCE & ASSOCIATES LP 0.19% of their portfolio | 920.3k $18.4m | Added +414.4k |
| Man Group plc 0.03% of their portfolio | 850.7k $17.0m | Added +12.6k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 849.9k $17.0m | Reduced -131.4k |
| TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio | 839.9k $16.8m | Added +317.6k |
| Invesco Ltd. 0.00% of their portfolio | 832.6k $16.6m | Added +67.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 698.1k $14.0m | Reduced -5.7k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.01% of their portfolio | 696.9k $13.9m | Added +246.4k |
| Nuveen, LLC 0.00% of their portfolio | 647.5k $12.9m | Reduced -743.8k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 647.3k $12.9m | New |
| BARCLAYS PLC 0.00% of their portfolio | 588.5k $11.8m | Added +253.8k |
| UBS Group AG 0.00% of their portfolio | 508.2k $10.2m | Reduced -64.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 483.0k $9.7m | Added +36.1k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio | 481.8k $9.6m | Added +11.0k |
| Assenagon Asset Management S.A. 0.01% of their portfolio | 444.2k $8.9m | Unchanged |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 433.2k $8.7m | Added +49.4k |
| Pacer Advisors, Inc. 0.02% of their portfolio | 381.4k $7.6m | Reduced -83.2k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 371.4k $7.4m | Reduced -364.3k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 371.1k $7.4m | Added +68.6k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 368.0k $7.4m | Reduced -143.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 339.1k $6.8m | Added +49.4k |
| Allianz Asset Management GmbH 0.01% of their portfolio | 336.9k $6.7m | Added +140.1k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 330.8k $6.6m | Added +33.9k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 253.1k $4.5m | Reduced -5.2k |
| NOMURA HOLDINGS INC 0.01% of their portfolio | 246.5k $4.9m | Added +13.4k |
| Public Sector Pension Investment Board 0.02% of their portfolio | 245.8k $4.9m | Added +12.3k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 244.0k $4.9m | Added +91.5k |
| INTECH INVESTMENT MANAGEMENT LLC 0.04% of their portfolio | 220.2k $4.4m | Added +183.5k |
| Uniplan Investment Counsel, Inc. 0.44% of their portfolio | 219.5k $4.4m | Added +28.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 199.4k $4.0m | Added +5.4k |
| Legal & General Group Plc 0.00% of their portfolio | 190.6k $3.8m | Added +6.8k |
| ASSETMARK, INC 0.01% of their portfolio | 185.3k $3.7m | Added +7.0k |
| Integrated Wealth Concepts LLC 0.04% of their portfolio | 183.7k $3.7m | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 178.3k $3.6m | Reduced -808.7k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio | 173.1k $3.5m | Added +57.6k |
| EXCHANGE TRADED CONCEPTS, LLC 0.03% of their portfolio | 171.9k $3.4m | Added +2.5k |
| WINTON GROUP Ltd 0.12% of their portfolio | 169.9k $3.4m | New |
| Trexquant Investment LP 0.03% of their portfolio | 163.1k $3.3m | Added +112.1k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 157.0k $3.1m | Added +64.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 149.8k $3.0m | Reduced -288.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 145.0k $2.9m | Added +7.9k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 135.7k $2.7m | Reduced -10.2k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 133.9k $2.7m | Added +133.6k |
| Gotham Asset Management, LLC 0.01% of their portfolio | 129.5k $2.6m | Added +16.8k |
| Susquehanna Portfolio Strategies, LLC 0.04% of their portfolio | 129.0k $2.6m | Added +84.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 124.0k $2.5m | Added +15.7k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 118.6k $2.4m | Added +53.3k |
| Swiss National Bank 0.00% of their portfolio | 118.1k $2.4m | Added +2.5k |
| ALGERT GLOBAL LLC 0.04% of their portfolio | 118.0k $2.4m | Added +106.9k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 113.8k $2.3m | New |
| Brandywine Global Investment Management, LLC 0.01% of their portfolio | 111.7k $2.2m | New |
| MARTINGALE ASSET MANAGEMENT L P 0.05% of their portfolio | 107.1k $2.1m | Added +27.7k |
| Orion Porfolio Solutions, LLC 0.02% of their portfolio | 105.2k $2.1m | Added +3.3k |
| HUSSMAN STRATEGIC ADVISORS, INC. 0.51% of their portfolio | 105.0k $2.1m | Added +63.0k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.04% of their portfolio | 103.4k $2.1m | Reduced -11.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 93.5k $1.9m | Reduced -35.2k |
| Freestone Grove Partners LP 0.01% of their portfolio | 91.7k $1.8m | Reduced -84.7k |
| Verition Fund Management LLC 0.01% of their portfolio | 91.6k $1.8m | Reduced -84.2k |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC 0.01% of their portfolio | 91.3k $1.8m | Reduced -32.9k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 87.1k $1.7m | Added +40.4k |
| CAXTON ASSOCIATES LLP 0.03% of their portfolio | 85.0k $1.7m | Added +57.0k |
| Oliver Luxxe Assets LLC 0.26% of their portfolio | 84.7k $1.7m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 84.6k $1.7m | Reduced -71.1k |
| QRG CAPITAL MANAGEMENT, INC. 0.02% of their portfolio | 79.7k $1.6m | Reduced -678 |
| DENALI ADVISORS LLC 0.17% of their portfolio | 77.2k $1.5m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 77.2k $1.5m | Added +4.7k |
| JAMES INVESTMENT RESEARCH, INC. 0.17% of their portfolio | 77.2k $1.5m | Unchanged |
| KLP KAPITALFORVALTNING AS 0.01% of their portfolio | 75.5k $1.5m | Added +9.4k |
| Engineers Gate Manager LP 0.02% of their portfolio | 75.3k $1.5m | Reduced -58.1k |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 75.0k $1.5m | Reduced -25.0k |
| Empowered Funds, LLC 0.03% of their portfolio | 74.6k $1.5m | New |
| Synergy Asset Management, LLC 0.15% of their portfolio | 74.4k $1.5m | Reduced -27.1k |
| Legato Capital Management LLC 0.12% of their portfolio | 71.3k $1.4m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 70.2k $1.4m | Added +29.3k |
| Creative Planning 0.00% of their portfolio | 70.1k $1.4m | Added +8.7k |
| CHASE INVESTMENT COUNSEL CORP 0.39% of their portfolio | 70.0k $1.4m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 66.6k $1.3m | Unchanged |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 63.5k $1.3m | Added +11.9k |
| Inspire Investing, LLC 0.11% of their portfolio | 62.5k $1.2m | New |
| FOX RUN MANAGEMENT, L.L.C. 0.19% of their portfolio | 61.7k $1.2m | New |
| LSV ASSET MANAGEMENT 0.00% of their portfolio | 58.0k $1.2m | Added +17.9k |
| Campbell & CO Investment Adviser LLC 0.06% of their portfolio | 57.9k $1.2m | Added +45.9k |