Vault-13

INSPIRE MED SYS INC INSP

COM · Common Stock · CUSIP 457730109 · ISIN US4577301090

Company in Maple Grove, United States

327 institutional holders -16 vs Q4 2023
32,680,11532.7m shares reported held*
110.0% of all shares outstanding*
$7.0bnreported value*
41 new 124 added 108 reduced 54 sold out net bought ≈ $182.2m (+846.9k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.0m this quarter). Holder counts are more reliable. Shares outstanding: 29.7m as of 2024-05-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $214.87. Options: 20 managers hold calls ($130.1m notional), 26 hold puts ($162.8m).

Trends to Q1 2024

Institutional holders

Managers reporting a position, each quarter

0200400600Q3 22: 302Q4 22: 339Q1 23: 373Q2 23: 408Q3 23: 366Q4 23: 343Q1 24: 327327Q3 22Q1 23Q3 23Q1 24
Numbers
QuarterHolders
Q3 2022302
Q4 2022339
Q1 2023373
Q2 2023408
Q3 2023366
Q4 2023343
Q1 2024327

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q4 22: 185 bought or addedQ4 22: 137 cut or sold outQ4 22Q1 23: 217 bought or addedQ1 23: 129 cut or sold outQ1 23Q2 23: 209 bought or addedQ2 23: 192 cut or sold outQ2 23Q3 23: 192 bought or addedQ3 23: 209 cut or sold outQ3 23Q4 23: 171 bought or addedQ4 23: 202 cut or sold outQ4 23Q1 24: 165 bought or addedQ1 24: 162 cut or sold outQ1 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022185137
Q1 2023217129
Q2 2023209192
Q3 2023192209
Q4 2023171202
Q1 2024165162

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ2 23 calls: $76.8mQ2 23 puts: $73.3mQ2 23P/C 0.95Q3 23 calls: $68.4mQ3 23 puts: $140.9mQ3 23P/C 2.06Q4 23 calls: $80.1mQ4 23 puts: $112.5mQ4 23P/C 1.40Q1 24 calls: $130.1mQ1 24 puts: $162.8mQ1 24P/C 1.25
Numbers
QuarterCallsPutsP/C
Q2 2023$76.8m$73.3m0.95
Q3 2023$68.4m$140.9m2.06
Q4 2023$80.1m$112.5m1.40
Q1 2024$130.1m$162.8m1.25

Biggest buyers

FMR LLC Added +1,180,221+1.2m
WELLINGTON MANAGEMENT GROUP LLP Added +522,392+522.4k
AMERICAN CENTURY COMPANIES INC Added +335,074+335.1k
Artisan Partners Limited Partnership New +301,174+301.2k
BAILLIE GIFFORD & CO Added +237,734+237.7k
Bank of New York Mellon Corp Added +197,097+197.1k
PRICE T ROWE ASSOCIATES INC /MD/ Added +156,893+156.9k
Ensign Peak Advisors, Inc Added +92,920+92.9k
BlackRock Inc. Added +90,812+90.8k
CITADEL ADVISORS LLC Added +88,706+88.7k

Biggest sellers

Slate Path Capital LP Sold out -294,000-294.0k
MARSHALL WACE, LLP Sold out -247,641-247.6k
FARALLON CAPITAL MANAGEMENT, L.L.C. Reduced -228,242-228.2k
Point72 Asset Management, L.P. Reduced -210,894-210.9k
FRANKLIN RESOURCES INC Reduced -204,083-204.1k
FRED ALGER MANAGEMENT, LLC Reduced -183,347-183.3k
D. E. Shaw & Co., Inc. Reduced -153,460-153.5k
Iron Triangle Partners LP Sold out -150,000-150.0k
INTRINSIC EDGE CAPITAL MANAGEMENT LLC Reduced -148,908-148.9k
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC Sold out -141,777-141.8k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $23.9m111.3k shares
CITADEL ADVISORS LLC Added $22.5m104.9k shares
JANE STREET GROUP, LLC Added $14.6m67.8k shares
MILLENNIUM MANAGEMENT LLC Added $13.3m62.1k shares
Squarepoint Ops LLC Added $11.9m55.5k shares
SIMPLEX TRADING, LLC Added $9.4m43.6k shares
Point72 Asset Management, L.P. New $8.6m40.0k shares
Caption Management, LLC New $5.5m25.8k shares
CAPITAL FUND MANAGEMENT S.A. Reduced $4.8m22.4k shares
WOLVERINE TRADING, LLC Added $3.4m16.0k shares

Biggest puts

CITADEL ADVISORS LLC Added $25.6m119.1k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $22.8m106.2k shares
MILLENNIUM MANAGEMENT LLC Reduced $15.2m70.7k shares
Caption Management, LLC New $14.3m66.7k shares
D. E. Shaw & Co., Inc. Reduced $12.9m60.1k shares
Squarepoint Ops LLC New $12.8m59.6k shares
SIMPLEX TRADING, LLC Added $11.3m52.6k shares
CAPITAL FUND MANAGEMENT S.A. Reduced $9.7m45.2k shares
FIRST SABREPOINT CAPITAL MANAGEMENT LP New $6.9m32.0k shares
Walleye Trading LLC Added $4.5m21.1k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BlackRock, Inc. 13G · institution +3.1 pts · filed 2026-07-28 14.4% +3.1 pts 4.2m≈ $185.7m 2026-07-28
WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.2 pts · filed 2026-05-15 8.8% +1.2 pts 2.5m≈ $113.1m 2026-05-15
VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.7 pts · filed 2026-07-31 7.4% +1.7 pts 2.1m≈ $94.8m 2026-07-31
Soleus Capital Master Fund, L.P. 13G · passive investor +1.6 pts · filed 2026-08-13 6.7% +1.6 pts 1.9m≈ $86.2m 2026-08-13
AQR CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-08-12 6.4% new 1.9m≈ $82.8m 2026-08-12
D. E. SHAW & CO, L.P. 13G · passive investor new · filed 2026-07-02 5.1% new 1.5m≈ $66.2m 2026-07-02
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.1% new 1.5m≈ $65.6m 2026-04-30

Fell to 5% or below in the last year: Flynn James E (4.5%, 2026-05-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), CITADEL ADVISORS LLC (1.8%, 2026-02-17), Dragoneer Investment Group, LLC (0.0%, 2025-11-14)

Insider purchases and sales in Q1 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
505Q2 22: 0 buyingQ2 22: 2 sellingQ3 22: 0 buyingQ3 22: 0 sellingQ3 22Q4 22: 0 buyingQ4 22: 4 sellingQ1 23: 0 buyingQ1 23: 5 sellingQ1 23Q2 23: 0 buyingQ2 23: 2 sellingQ3 23: 0 buyingQ3 23: 2 sellingQ3 23Q4 23: 1 buyingQ4 23: 0 sellingQ1 24: 0 buyingQ1 24: 3 sellingQ1 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20220—2$6.6m—
Q3 20220—0——
Q4 20220—4$10.8m—
Q1 20230—5$21.8m—
Q2 20230—2$5.3m$4.9m
Q3 20230—2$822.5k$822.5k
Q4 20231$15.3k0——
Q1 20240—3$5.6m$2.8m
DateInsiderTradeSharesPrice ValueTheir holding
2024-03-25 Griffin Jerry C Director Sold plan 554 $197.81 $109.6k554 shares -5%
2024-03-22 Rondoni John Chief Technology Officer Sold plan 4,387 $194.40 $852.8k4.4k shares -28%
2024-03-18 Griffin Jerry C Director Sold plan 554 $193.53 $107.2k554 shares -5%
2024-03-11 Griffin Jerry C Director Sold plan 554 $198.05 $109.7k554 shares -5%
2024-03-01 Griffin Jerry C Director Sold plan 554 $179.44 $99.4k554 shares -6%
2024-02-29 Rondoni John Chief Technology Officer Sold plan 8,605 $179.25 $1.5m8.6k shares -36%
2024-02-27 Ban Randy Chief Commercial Officer Sold 3,060 $182.01 $557.0k3.1k shares -50%
2024-02-23 Ban Randy Chief Commercial Officer Sold 12,230 $185.37 $2.3m12.2k shares -80%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q1 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.06% of their portfolio BOSTON, MA 4,437,7654.4m $953.2m $953.2m 0.06% Added +1.2m +1,180,221
2 VANGUARD GROUP INC 0.01% of their portfolio Valley Forge, PA 2,892,4042.9m $621.3m $621.3m 0.01% Reduced -39.1k -39,065
3 WELLINGTON MANAGEMENT GROUP LLP 0.07% of their portfolio Boston, MA 1,952,6582.0m $419.4m $419.4m 0.07% Added +522.4k +522,392
4 BlackRock Inc. 0.01% of their portfolio New York, NY 1,891,0191.9m $406.2m $406.2m 0.01% Added +90.8k +90,812
5 BAILLIE GIFFORD & CO 0.25% of their portfolio EDINBURGH, X0 1,467,6131.5m $315.2m $315.2m 0.25% Added +237.7k +237,734
6 JPMORGAN CHASE & CO 0.01% of their portfolio NEW YORK, NY 1,236,3001.2m $265.5m $265.5m 0.01% Reduced -27.5k -27,462
7 WASATCH ADVISORS LP 1.24% of their portfolio SALT LAKE CITY, UT 1,102,8671.1m $236.9m $236.9m 1.24% Added +5.5k +5,522
8 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.42% of their portfolio CHICAGO, IL 756,811756.8k $162.6m $162.6m 0.42% Reduced -50.1k -50,136
9 FRONTIER CAPITAL MANAGEMENT CO LLC 1.37% of their portfolio Boston, MA 684,740684.7k $147.1m $147.1m 1.37% Reduced -57.3k -57,306
10 Champlain Investment Partners, LLC 0.79% of their portfolio BURLINGTON, VT 641,685641.7k $137.8m $137.8m 0.79% Reduced -6.9k -6,910
11 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.79% of their portfolio SAN FRANCISCO, CA 626,854626.9k $134.6m $134.6m 0.79% Reduced -228.2k -228,242
12 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 595,577595.6k $127.9m $127.9m 0.02% Added +197.1k +197,097
13 MACQUARIE GROUP LTD 0.14% of their portfolio Sydney, NSW 2000, C3 558,485558.5k $120.0m $120.0m 0.14% Added +19.9k +19,910
14 WESTFIELD CAPITAL MANAGEMENT CO LP 0.61% of their portfolio BOSTON, MA 538,294538.3k $115.6m $115.6m 0.61% Reduced -7.3k -7,325
15 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 530,200530.2k $113.9m $113.9m 0.01% Reduced -993 -993
16 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 462,320462.3k $99.3m $99.3m 0.01% Added +17.5k +17,506
17 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 459,766459.8k $98.8m $98.8m 0.01% Added +156.9k +156,893
18 FEDERATED HERMES, INC. 0.22% of their portfolio PITTSBURGH, PA 453,200453.2k $97.3m $97.3m 0.22% Reduced -68 -68
19 AMERIPRISE FINANCIAL INC 0.03% of their portfolio MINNEAPOLIS, MN 431,443431.4k $92.7m $92.7m 0.03% Reduced -59.8k -59,827
20 Eversept Partners, LP 6.75% of their portfolio NEW YORK, NY 420,699420.7k $90.4m $90.4m 6.75% Added +69.6k +69,583
21 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 409,713409.7k $88.0m $88.0m 0.00% Added +62.6k +62,587
22 AMERICAN CENTURY COMPANIES INC 0.05% of their portfolio KANSAS CITY, MO 338,376338.4k $72.7m $72.7m 0.05% Added +335.1k +335,074
23 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 309,929309.9k $66.6m $66.6m 0.02% Reduced -204.1k -204,083
24 Artisan Partners Limited Partnership 0.09% of their portfolio Milwaukee, WI 301,174301.2k $64.7m $64.7m 0.09% New
25 CREDIT SUISSE AG/ 0.06% of their portfolio ZURICH, V8 297,084297.1k $63.8m $63.8m 0.06% Reduced -59.0k -58,975
26 NORGES BANK 0.01% of their portfolio OSLO, Q8 274,536274.5k $59.0m $59.0m 0.01% Added +33.1k +33,096
27 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 268,887268.9k $57.8m $57.8m 0.01% Added +4.9k +4,949
28 Point72 Asset Management, L.P. 0.16% of their portfolio STAMFORD, CT 262,301262.3k $56.3m $56.3m 0.16% Reduced -210.9k -210,894
29 JENNISON ASSOCIATES LLC 0.04% of their portfolio NEW YORK, NY 257,854257.9k $55.4m $55.4m 0.04% Reduced -47.0k -47,032
30 GILDER GAGNON HOWE & CO LLC 0.67% of their portfolio New York, NY 250,723250.7k $53.9m $53.9m 0.67% Reduced -5.2k -5,237
31 VOYA INVESTMENT MANAGEMENT LLC 0.05% of their portfolio ATLANTA, GA 225,747225.7k $48.5m $48.5m 0.05% Added +63.4k +63,417
32 FRED ALGER MANAGEMENT, LLC 0.24% of their portfolio NEW YORK, NY 222,560222.6k $47.8m $47.8m 0.24% Reduced -183.3k -183,347
33 Bellevue Group AG 0.71% of their portfolio ZURICH, V8 217,694217.7k $46.8m $46.8m 0.71% Added +2.1k +2,094
34 BAMCO INC /NY/ 0.12% of their portfolio NEW YORK, NY 210,000210.0k $45.1m $45.1m 0.12% Reduced -1.0k -1,000
35 KEYBANK NATIONAL ASSOCIATION/OH 0.18% of their portfolio BROOKLYN, OH 201,669201.7k $43.3m $43.3m 0.18% Added +332 +332
36 Hood River Capital Management LLC 0.91% of their portfolio PALM BEACH GARDENS, FL 189,237189.2k $40.6m $40.6m 0.91% Added +32.8k +32,796
37 Allspring Global Investments Holdings, LLC 0.06% of their portfolio CHARLOTTE, NC 166,590166.6k $35.8m $35.8m 0.06% Reduced -53.2k -53,245
38 Ensign Peak Advisors, Inc 0.06% of their portfolio SALT LAKE CITY, UT 163,636163.6k $35.1m $35.1m 0.06% Added +92.9k +92,920
39 NORTHERN TRUST CORP 0.01% of their portfolio CHICAGO, IL 154,384154.4k $33.2m $33.2m 0.01% Reduced -839 -839
40 Driehaus Capital Management LLC 0.31% of their portfolio Chicago, IL 142,881142.9k $30.7m $30.7m 0.31% Reduced -59.1k -59,069
41 First Light Asset Management, LLC 2.30% of their portfolio Edina, MN 139,951140.0k $30.1m $30.1m 2.30% Added +51.4k +51,428
42 Nuveen Asset Management, LLC 0.01% of their portfolio CHICAGO, IL 134,951135.0k $29.0m $29.0m 0.01% Added +36.5k +36,458
43 Rock Springs Capital Management LP 0.71% of their portfolio Baltimore, MD 130,500130.5k $28.0m $28.0m 0.71% Added +31.5k +31,500
44 Degroof Petercam Asset Management 0.34% of their portfolio Brussels, C9 130,000130.0k $27.9m $27.9m 0.34% Added +20.0k +20,000
45 Atika Capital Management LLC 3.13% of their portfolio NEW YORK, NY 129,735129.7k $27.9m $27.9m 3.13% Added +8.1k +8,135
46 EVENTIDE ASSET MANAGEMENT, LLC 0.42% of their portfolio Boston, MA 125,090125.1k $26.9m $26.9m 0.42% Unchanged
47 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio Boston, MA 125,000125.0k $26.8m $26.8m 0.05% Reduced -84.9k -84,916
48 Eagle Health Investments LP 5.00% of their portfolio Greenwich, CT 122,203122.2k $26.2m $26.2m 5.00% Added +8.7k +8,700
49 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 120,566120.6k $25.9m $25.9m 0.00% Added +51.3k +51,312
50 RENAISSANCE TECHNOLOGIES LLC 0.04% of their portfolio NEW YORK, NY 109,600109.6k $23.5m $23.5m 0.04% Reduced -4.0k -4,000
51 Thrivent Financial for Lutherans 0.05% of their portfolio Minneapolis, MN 105,040105.0k $22.6m $22.6m 0.05% Reduced -3.9k -3,882
52 VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio San Antonio, TX 104,971105.0k $22.5m $22.5m 0.02% Reduced -37.9k -37,850
53 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 102,721102.7k $22.1m $22.1m 0.00% Added +67.7k +67,701
54 Susquehanna Portfolio Strategies, LLC 0.51% of their portfolio Bala Cynwyd, PA 101,600101.6k $21.8m $21.8m 0.51% Unchanged
55 BRAIDWELL LP 0.70% of their portfolio STAMFORD, CT 101,492101.5k $21.8m $21.8m 0.70% Reduced -83.2k -83,166
56 Mitsubishi UFJ Trust & Banking Corp 0.05% of their portfolio TOKYO, M0 100,880100.9k $21.7m $21.7m 0.05% Reduced -9.1k -9,080
57 SEI INVESTMENTS CO 0.03% of their portfolio OAKS, PA 93,66693.7k $20.1m $20.1m 0.03% Added +8.3k +8,301
58 CITADEL ADVISORS LLC 0.02% of their portfolio MIAMI, FL 92,99193.0k $20.0m $20.0m 0.02% Added +88.7k +88,706
59 Connor, Clark & Lunn Investment Management Ltd. 0.09% of their portfolio VANCOUVER, A1 92,41992.4k $19.9m $19.9m 0.09% Added +13.9k +13,949
60 AQR CAPITAL MANAGEMENT LLC 0.03% of their portfolio Greenwich, CT 91,75591.8k $19.7m $19.7m 0.03% Added +28.3k +28,312
61 Amundi 0.01% of their portfolio Paris, I0 84,59784.6k $20.4m $20.4m 0.01% Added +26.9k +26,858
62 Parkman Healthcare Partners LLC 2.14% of their portfolio STAMFORD, CT 81,18381.2k $17.4m $17.4m 2.14% Reduced -22.6k -22,563
63 ExodusPoint Capital Management, LP 0.21% of their portfolio NEW YORK, NY 79,48879.5k $17.1m $17.1m 0.21% Reduced -9.3k -9,276
64 Rheos Capital Works Inc. 0.82% of their portfolio Tokyo, M0 79,40079.4k $17.1m $17.1m 0.82% Added +16.3k +16,300
65 COMERICA BANK 0.07% of their portfolio DALLAS, TX 79,03079.0k $17.0m $17.0m 0.07% Added +8.5k +8,454
66 BROWN CAPITAL MANAGEMENT LLC 0.30% of their portfolio BALTIMORE, MD 78,39978.4k $16.8m $16.8m 0.30% New
67 Balyasny Asset Management L.P. 0.04% of their portfolio Chicago, IL 76,97577.0k $16.5m $16.5m 0.04% Reduced -23.9k -23,852
68 KORNITZER CAPITAL MANAGEMENT INC /KS 0.28% of their portfolio SHAWNEE MISSION, KS 70,90070.9k $15.2m $15.2m 0.28% Reduced -1.2k -1,250
69 NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio ALBANY, NY 70,21770.2k $15.1m $15.1m 0.02% Added +48.3k +48,317
70 NOVO HOLDINGS A/S 0.97% of their portfolio HELLERUP, G7 65,52465.5k $14.1m $14.1m 0.97% Unchanged
71 NOMURA ASSET MANAGEMENT CO LTD 0.05% of their portfolio TOKYO, M0 64,86864.9k $13.9m $13.9m 0.05% Added +4.7k +4,681
72 LAZARD ASSET MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 63,19663.2k $13.6m $13.6m 0.02% Added +29.0k +29,039
73 Schonfeld Strategic Advisors LLC 0.11% of their portfolio NEW YORK, NY 63,12563.1k $13.6m $13.6m 0.11% Reduced -44.2k -44,217
74 NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio NEW YORK, NY 62,57662.6k $13.4m $13.4m 0.01% Added +11.7k +11,719
75 CANADA PENSION PLAN INVESTMENT BOARD 0.01% of their portfolio TORONTO ONTARIO, A6 61,60061.6k $13.2m $13.2m 0.01% Reduced -8.4k -8,400
76 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 60,97061.0k $13.1m $13.1m 0.00% Added +38.3k +38,287
77 MAIRS & POWER INC 0.12% of their portfolio St Paul, MN 59,18859.2k $12.7m $12.7m 0.12% Reduced -5.4k -5,421
78 Swiss National Bank 0.01% of their portfolio ZURICH, V8 58,30058.3k $12.5m $12.5m 0.01% Added +500 +500
79 STATE OF WISCONSIN INVESTMENT BOARD 0.03% of their portfolio MADISON, WI 55,63255.6k $11.9m $11.9m 0.03% Reduced -6.8k -6,826
80 Stanley-Laman Group, Ltd. 1.52% of their portfolio Berwyn, PA 50,41250.4k $10.8m $10.8m 1.52% Reduced -639 -639
81 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 47,10947.1k $10.1m $10.1m 0.00% Reduced -55.8k -55,847
82 Aberdeen Group plc 0.02% of their portfolio EDINBURGH, X0 45,96146.0k $9.9m $9.9m 0.02% Unchanged
83 CAPITAL FUND MANAGEMENT S.A. 0.12% of their portfolio PARIS, I0 45,44345.4k $9.8m $9.8m 0.12% Added +3.9k +3,927
84 Rhenman & Partners Asset Management AB 0.86% of their portfolio Stockholm, V7 42,00042.0k $9.0m $9.0m 0.86% Added +24.0k +24,000
85 Kopp LeRoy C 5.04% of their portfolio BLOOMINGTON, MN 41,05441.1k $8.8m $8.8m 5.04% First filing
86 Kopp Family Office, LLC 5.04% of their portfolio MINNETONKA, MN 41,05441.1k $8.8m $8.8m 5.04% Added +7.8k +7,829
87 TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.08% of their portfolio FRANKFORT, KY 40,50140.5k $8.7m $8.7m 0.08% Added +8.6k +8,625
88 Man Group plc 0.02% of their portfolio LONDON, X0 40,36440.4k $8.7m $8.7m 0.02% Reduced -106 -106
89 California Public Employees Retirement System 0.01% of their portfolio Sacramento, CA 40,33740.3k $8.7m $8.7m 0.01% Unchanged
90 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 39,41839.4k $8.5m $8.5m 0.00% Added +2.2k +2,249
91 HSBC HOLDINGS PLC 0.01% of their portfolio LONDON, X0 37,30637.3k $8.0m $8.0m 0.01% Added +16.1k +16,121
92 RHUMBLINE ADVISERS 0.01% of their portfolio BOSTON, MA 35,55735.6k $7.6m $7.6m 0.01% Reduced -3.2k -3,224
93 INTRINSIC EDGE CAPITAL MANAGEMENT LLC 0.62% of their portfolio CHICAGO, IL 33,93833.9k $7.3m $7.3m 0.62% Reduced -148.9k -148,908
94 LMCG INVESTMENTS, LLC 0.43% of their portfolio BOSTON, MA 33,89233.9k $7.3m $7.3m 0.43% New
95 ARMISTICE CAPITAL, LLC 0.19% of their portfolio NEW YORK, NY 33,75433.8k $7.3m $7.3m 0.19% Reduced -2.8k -2,768
96 OSTERWEIS CAPITAL MANAGEMENT INC 0.42% of their portfolio SAN FRANCISCO, CA 33,68633.7k $7.2m $7.2m 0.42% Added +4.7k +4,709
97 PFM Health Sciences, LP 0.36% of their portfolio SAN FRANCISCO, CA 33,55733.6k $7.2m $7.2m 0.36% New
98 Integral Health Asset Management, LLC 0.70% of their portfolio New York, NY 33,00033.0k $7.1m $7.1m 0.70% Reduced -27.0k -27,000
99 NEXT CENTURY GROWTH INVESTORS LLC 0.61% of their portfolio PLYMOUTH, MN 32,45732.5k $7.0m $7.0m 0.61% Added +1.1k +1,121
100 UBS Group AG 0.00% of their portfolio ZURICH, V8 32,18732.2k $6.9m $6.9m 0.00% Reduced -986 -986