Vault-13

INSMED INC INSM

COM PAR $.01 · Common Stock · CUSIP 457669307 · ISIN US4576693075

417 institutional holders +37 vs Q2 2024
191,030,309191.0m shares reported held*
106.8% of all shares outstanding*
$14.0bnreported value*
72 new 185 added 114 reduced 38 sold out net bought ≈ $873.4m (+12.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($27.7m this quarter). Holder counts are more reliable. Shares outstanding: 178.9m as of 2024-10-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $73.03. Options: 30 managers hold calls ($175.9m notional), 25 hold puts ($270.0m).

Trends to Q3 2024

Institutional holders

Managers reporting a position, each quarter

0200400600Q3 22: 239Q4 22: 226Q1 23: 232Q2 23: 225Q3 23: 254Q4 23: 273Q1 24: 290Q2 24: 380Q3 24: 417417Q3 22Q1 23Q3 23Q1 24Q3 24
Numbers
QuarterHolders
Q3 2022239
Q4 2022226
Q1 2023232
Q2 2023225
Q3 2023254
Q4 2023273
Q1 2024290
Q2 2024380
Q3 2024417

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q4 22: 132 bought or addedQ4 22: 104 cut or sold outQ1 23: 123 bought or addedQ1 23: 97 cut or sold outQ1 23Q2 23: 103 bought or addedQ2 23: 111 cut or sold outQ3 23: 133 bought or addedQ3 23: 95 cut or sold outQ3 23Q4 23: 131 bought or addedQ4 23: 111 cut or sold outQ1 24: 141 bought or addedQ1 24: 126 cut or sold outQ1 24Q2 24: 257 bought or addedQ2 24: 137 cut or sold outQ3 24: 257 bought or addedQ3 24: 152 cut or sold outQ3 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022132104
Q1 202312397
Q2 2023103111
Q3 202313395
Q4 2023131111
Q1 2024141126
Q2 2024257137
Q3 2024257152

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200m$400m$600mQ4 23 calls: $10.0mQ4 23 puts: $52.2mQ4 23P/C 5.19Q1 24 calls: $68.3mQ1 24 puts: $84.5mQ1 24P/C 1.24Q2 24 calls: $470.9mQ2 24 puts: $343.5mQ2 24P/C 0.73Q3 24 calls: $175.9mQ3 24 puts: $270.0mQ3 24P/C 1.54
Numbers
QuarterCallsPutsP/C
Q4 2023$10.0m$52.2m5.19
Q1 2024$68.3m$84.5m1.24
Q2 2024$470.9m$343.5m0.73
Q3 2024$175.9m$270.0m1.54

Biggest buyers

Darwin Global Management, Ltd. Added +6,956,182+7.0m
STATE STREET CORP Added +1,515,791+1.5m
VANGUARD GROUP INC Added +1,130,167+1.1m
FIL Ltd Added +921,634+921.6k
Vestal Point Capital, LP Added +850,000+850.0k
BAKER BROS. ADVISORS LP Added +839,880+839.9k
JPMORGAN CHASE & CO Added +760,322+760.3k
TWO SIGMA INVESTMENTS, LP Added +693,395+693.4k
Capital International Investors Added +653,903+653.9k
Man Group plc Added +575,513+575.5k

Biggest sellers

Deep Track Capital, LP Sold out -2,000,000-2.0m
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC Reduced -1,048,820-1.0m
VIKING GLOBAL INVESTORS LP Sold out -1,035,970-1.0m
MONTANOVA CAPITAL, LLC Reduced -886,091-886.1k
MILLENNIUM MANAGEMENT LLC Reduced -633,654-633.7k
JANUS HENDERSON GROUP PLC Reduced -602,874-602.9k
FARALLON CAPITAL MANAGEMENT, L.L.C. Reduced -565,000-565.0k
Point72 Asset Management, L.P. Reduced -543,149-543.1k
Bellevue Group AG Reduced -496,266-496.3k
MARSHALL WACE, LLP Reduced -478,140-478.1k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $32.3m441.9k shares
Twin Tree Management, LP Added $26.7m366.1k shares
BOOTHBAY FUND MANAGEMENT, LLC Added $19.3m264.7k shares
JANE STREET GROUP, LLC Added $19.2m263.3k shares
Octagon Capital Advisors LP Unchanged $18.2m250.0k shares
MILLENNIUM MANAGEMENT LLC Added $7.8m107.4k shares
Caption Management, LLC Reduced $6.8m92.8k shares
CITADEL ADVISORS LLC Reduced $6.0m81.6k shares
NOMURA HOLDINGS INC Reduced $5.8m80.0k shares
JPMORGAN CHASE & CO Reduced $5.4m73.6k shares

Biggest puts

JANE STREET GROUP, LLC New $76.1m1.0m shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $38.2m523.6k shares
Caption Management, LLC Reduced $31.1m426.5k shares
Parallax Volatility Advisers, L.P. Reduced $23.6m323.8k shares
CITADEL ADVISORS LLC Reduced $20.4m279.3k shares
GROUP ONE TRADING LLC New $18.4m252.1k shares
SIMPLEX TRADING, LLC New $14.0m191.9k shares
Twin Tree Management, LP Added $12.5m171.2k shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC New $10.9m150.0k shares
UBS Group AG Unchanged $9.4m128.2k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 7.4% +1.3 pts 16.1m≈ $1.7bn 2026-08-06
BlackRock, Inc. 13G · institution +1.5 pts · filed 2026-01-21 6.6% +1.5 pts 14.1m≈ $1.5bn 2026-01-21
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.3% new 11.5m≈ $1.2bn 2026-04-30

Fell to 5% or below in the last year: Darwin Global Management, Ltd. (3.0%, 2026-08-14), JPMORGAN CHASE & CO (4.7%, 2026-07-22), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), PRICE T ROWE ASSOCIATES INC /MD/ (3.3%, 2025-11-14)

Insider purchases and sales in Q3 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q4 22: 2 buyingQ4 22: 2 sellingQ1 23: 0 buyingQ1 23: 7 sellingQ1 23Q2 23: 1 buyingQ2 23: 7 sellingQ3 23: 0 buyingQ3 23: 1 sellingQ3 23Q4 23: 0 buyingQ4 23: 4 sellingQ1 24: 0 buyingQ1 24: 7 sellingQ1 24Q2 24: 0 buyingQ2 24: 7 sellingQ3 24: 0 buyingQ3 24: 3 sellingQ3 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20222$1.3m2$357.7k—
Q1 20230—7$679.5k—
Q2 20231$385.8k7$1.2m$344.4k
Q3 20230—1$14.9k—
Q4 20230—4$4.7m$4.7m
Q1 20240—7$3.7m$3.0m
Q2 20240—7$28.7m$26.9m
Q3 20240—3$25.6m$18.4m
DateInsiderTradeSharesPrice ValueTheir holding
2024-09-16 Flammer Martina M.D. Chief Medical Officer Sold plan 13,436 $74.92 $1.0m13.4k shares -11%
2024-09-13 Smith Michael Alexander Chief Legal Officer Sold plan 27,871 $74.35 $2.1m27.9k shares -29%
2024-09-13 Flammer Martina M.D. Chief Medical Officer Sold plan 26,969 $74.90 $2.0m27.0k shares -20%
2024-09-12 Flammer Martina M.D. Chief Medical Officer Sold plan 635 $74.92 $47.6k635 shares -1%
2024-09-10 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold plan 37,575 $71.50 $2.7m37.6k shares -27%
2024-09-06 Flammer Martina M.D. Chief Medical Officer Sold plan 149,002 $71.23 $10.6m149.0k shares -58%
2024-08-12 Smith Michael Alexander Chief Legal Officer Sold 88,070 $72.96 $6.4m88.1k shares -50%
2024-08-12 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold 9,469 $72.49 $686.4k9.5k shares -9%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q3 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.02% of their portfolio Valley Forge, PA 17,143,17717.1m $1.3bn $1.3bn 0.02% Added +1.1m +1,130,167
2 BlackRock, Inc. 0.02% of their portfolio New York, NY 14,970,15215.0m $1.1bn $1.1bn 0.02% First filing
3 PRICE T ROWE ASSOCIATES INC /MD/ 0.11% of their portfolio BALTIMORE, MD 12,580,98112.6m $918.4m $918.4m 0.11% Added +417.6k +417,613
4 Darwin Global Management, Ltd. 62.31% of their portfolio ST. HELIER, Y9 10,497,27710.5m $766.3m $766.3m 62.31% Added +7.0m +6,956,182
5 FMR LLC 0.03% of their portfolio BOSTON, MA 7,191,5187.2m $525.0m $525.0m 0.03% Reduced -113.6k -113,612
6 JPMORGAN CHASE & CO 0.02% of their portfolio NEW YORK, NY 6,612,6926.6m $482.7m $482.7m 0.02% Added +760.3k +760,322
7 Capital International Investors 0.09% of their portfolio Los Angeles, CA 6,523,7916.5m $476.2m $476.2m 0.09% Added +653.9k +653,903
8 STATE STREET CORP 0.02% of their portfolio BOSTON, MA 6,178,2306.2m $451.0m $451.0m 0.02% Added +1.5m +1,515,791
9 BAKER BROS. ADVISORS LP 3.34% of their portfolio NEW YORK, NY 4,415,9184.4m $322.4m $322.4m 3.34% Added +839.9k +839,880
10 GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio BOSTON, MA 3,813,3843.8m $278.4m $278.4m 0.02% Added +172.7k +172,664
11 RTW INVESTMENTS, LP 3.46% of their portfolio NEW YORK, NY 3,272,0083.3m $238.9m $238.9m 3.46% Reduced -368.1k -368,100
12 Artisan Partners Limited Partnership 0.32% of their portfolio Milwaukee, WI 2,884,0972.9m $210.5m $210.5m 0.32% Added +394.7k +394,666
13 FRANKLIN RESOURCES INC 0.06% of their portfolio San Mateo, CA 2,721,3892.7m $204.3m $204.3m 0.06% Added +3.1k +3,099
14 AMERIPRISE FINANCIAL INC 0.05% of their portfolio MINNEAPOLIS, MN 2,580,4192.6m $188.4m $188.4m 0.05% Added +49.4k +49,425
15 ALLIANCEBERNSTEIN L.P. 0.06% of their portfolio NASHVILLE, TN 2,450,0932.5m $178.9m $178.9m 0.06% Reduced -42.2k -42,182
16 FIL Ltd 0.16% of their portfolio HAMILTON, D0 2,439,7482.4m $178.1m $178.1m 0.16% Added +921.6k +921,634
17 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.44% of their portfolio CHICAGO, IL 2,420,9082.4m $176.7m $176.7m 0.44% Reduced -1.0m -1,048,820
18 MACQUARIE GROUP LTD 0.18% of their portfolio Sydney, NSW 2000, C3 2,285,9212.3m $166.9m $166.9m 0.18% Reduced -460.7k -460,707
19 T. Rowe Price Investment Management, Inc. 0.10% of their portfolio BALTIMORE, MD 2,277,1432.3m $166.2m $166.2m 0.10% Reduced -158.8k -158,819
20 Palo Alto Investors LP 18.40% of their portfolio PALO ALTO, CA 1,940,9931.9m $141.7m $141.7m 18.40% Reduced -198.0k -197,970
21 PRINCIPAL FINANCIAL GROUP INC 0.07% of their portfolio DES MOINES, IA 1,871,8901.9m $136.6m $136.6m 0.07% Added +214.1k +214,130
22 Pictet Asset Management Holding SA 0.15% of their portfolio CAROUGE, V8 1,863,3411.9m $135.9m $135.9m 0.15% Added +372.2k +372,206
23 Clearbridge Investments, LLC 0.10% of their portfolio NEW YORK, NY 1,808,7671.8m $132.0m $132.0m 0.10% Added +163.8k +163,819
24 NORGES BANK 0.02% of their portfolio OSLO, Q8 1,656,7671.7m $120.9m $120.9m 0.02% Reduced -100.7k -100,658
25 MONTANOVA CAPITAL, LLC 4.29% of their portfolio New York, NY 1,635,7091.6m $119.4m $119.4m 4.29% Reduced -886.1k -886,091
26 Vestal Point Capital, LP 9.22% of their portfolio NEW YORK, NY 1,600,0001.6m $116.8m $116.8m 9.22% Added +850.0k +850,000
27 JANUS HENDERSON GROUP PLC 0.06% of their portfolio LONDON, X0 1,488,9041.5m $108.7m $108.7m 0.06% Reduced -602.9k -602,874
28 Hood River Capital Management LLC 1.74% of their portfolio PALM BEACH GARDENS, FL 1,472,5551.5m $107.5m $107.5m 1.74% Added +157.2k +157,163
29 LORD, ABBETT & CO. LLC 0.34% of their portfolio JERSEY CITY, NJ 1,470,9611.5m $107.4m $107.4m 0.34% Added +305.8k +305,807
30 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 1,470,2171.5m $107.3m $107.3m 0.02% Reduced -337.2k -337,153
31 NORTHERN TRUST CORP 0.02% of their portfolio CHICAGO, IL 1,459,9641.5m $106.6m $106.6m 0.02% Added +67.9k +67,857
32 Integral Health Asset Management, LLC 12.46% of their portfolio New York, NY 1,450,0001.4m $105.8m $105.8m 12.46% Reduced -100.0k -100,000
33 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio SAN FRANCISCO, CA 1,444,2661.4m $105.4m $105.4m 0.02% Added +137.7k +137,670
34 GOLDMAN SACHS GROUP INC 0.02% of their portfolio NEW YORK, NY 1,393,0491.4m $101.7m $101.7m 0.02% Added +203.1k +203,148
35 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 1,320,9911.3m $96.4m $96.4m 0.01% Added +498.2k +498,187
36 LOOMIS SAYLES & CO L P 0.12% of their portfolio BOSTON, MA 1,210,1871.2m $88.3m $88.3m 0.12% Reduced -16.5k -16,539
37 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 1,153,8981.2m $84.2m $84.2m 0.01% Added +34.7k +34,690
38 GW&K Investment Management, LLC 0.72% of their portfolio BOSTON, MA 1,153,5151.2m $84.2m $84.2m 0.72% Added +391.8k +391,783
39 Eversept Partners, LP 6.10% of their portfolio NEW YORK, NY 1,089,4041.1m $79.5m $79.5m 6.10% Reduced -66.2k -66,184
40 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 1,062,3951.1m $77.6m $77.6m 0.01% Added +306.2k +306,154
41 Nuveen Asset Management, LLC 0.02% of their portfolio CHICAGO, IL 1,061,1571.1m $77.5m $77.5m 0.02% Reduced -268.8k -268,790
42 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.13% of their portfolio Boston, MA 1,032,5621.0m $75.4m $75.4m 0.13% Reduced -292.4k -292,438
43 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 962,459962.5k $70.3m $70.3m 0.01% Added +24.0k +24,025
44 EVENTIDE ASSET MANAGEMENT, LLC 1.14% of their portfolio Boston, MA 906,395906.4k $66.2m $66.2m 1.14% Added +231.2k +231,210
45 Assenagon Asset Management S.A. 0.13% of their portfolio SENNINGERBERG, N4 857,360857.4k $62.6m $62.6m 0.13% Added +466.3k +466,306
46 TWO SIGMA INVESTMENTS, LP 0.13% of their portfolio NEW YORK, NY 801,139801.1k $58.5m $58.5m 0.13% Added +693.4k +693,395
47 MARSHALL WACE, LLP 0.07% of their portfolio LONDON, X0 771,211771.2k $56.3m $56.3m 0.07% Reduced -478.1k -478,140
48 JENNISON ASSOCIATES LLC 0.03% of their portfolio NEW YORK, NY 769,253769.3k $56.2m $56.2m 0.03% Added +25.0k +24,973
49 Alyeska Investment Group, L.P. 0.28% of their portfolio CHICAGO, IL 747,402747.4k $54.6m $54.6m 0.28% Added +318.6k +318,598
50 VOYA INVESTMENT MANAGEMENT LLC 0.06% of their portfolio ATLANTA, GA 745,794745.8k $54.4m $54.4m 0.06% Added +2.1k +2,069
51 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.20% of their portfolio JUPITER, FL 738,951739.0k $53.9m $53.9m 0.20% Reduced -183.1k -183,051
52 NOVO HOLDINGS A/S 2.63% of their portfolio HELLERUP, G7 724,666724.7k $52.9m $52.9m 2.63% Reduced -75.3k -75,334
53 AMERICAN CENTURY COMPANIES INC 0.03% of their portfolio KANSAS CITY, MO 723,683723.7k $52.8m $52.8m 0.03% Reduced -31.6k -31,588
54 EMERALD ADVISERS, LLC 1.95% of their portfolio LEOLA, PA 689,807689.8k $50.4m $50.4m 1.95% Added +49.5k +49,540
55 First Light Asset Management, LLC 4.18% of their portfolio Edina, MN 688,910688.9k $50.3m $50.3m 4.18% Added +137.6k +137,607
56 Rock Springs Capital Management LP 1.62% of their portfolio Baltimore, MD 683,344683.3k $49.9m $49.9m 1.62% Reduced -125.0k -125,012
57 Polar Capital Holdings Plc 0.28% of their portfolio London, X0 680,000680.0k $49.6m $49.6m 0.28% Added +425.0k +425,000
58 JANE STREET GROUP, LLC 0.08% of their portfolio NEW YORK, NY 659,675659.7k $48.2m $48.2m 0.08% Reduced -180.3k -180,325
59 Long Focus Capital Management, LLC 4.06% of their portfolio SAN JUAN, PR 628,900628.9k $45.9m $45.9m 4.06% Reduced -112.0k -112,000
60 Man Group plc 0.13% of their portfolio LONDON, X0 615,946615.9k $45.0m $45.0m 0.13% Added +575.5k +575,513
61 MPM BIOIMPACT LLC 6.74% of their portfolio BOSTON, MA 615,391615.4k $44.9m $44.9m 6.74% Unchanged
62 FRONTIER CAPITAL MANAGEMENT CO LLC 0.41% of their portfolio Boston, MA 594,106594.1k $43.4m $43.4m 0.41% Reduced -180.3k -180,298
63 Fiera Capital Corp 0.13% of their portfolio MONTREAL, A8 592,415592.4k $43.2m $43.2m 0.13% Reduced -13.1k -13,112
64 Avidity Partners Management LP 2.20% of their portfolio DALLAS, TX 592,000592.0k $43.2m $43.2m 2.20% Added +162.0k +162,000
65 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.90% of their portfolio Boston, MA 578,356578.4k $42.2m $42.2m 1.90% Added +306.8k +306,821
66 MILLENNIUM MANAGEMENT LLC 0.04% of their portfolio NEW YORK, NY 564,856564.9k $41.2m $41.2m 0.04% Reduced -633.7k -633,654
67 Bellevue Group AG 0.62% of their portfolio ZURICH, V8 525,434525.4k $38.4m $38.4m 0.62% Reduced -496.3k -496,266
68 Eagle Health Investments LP 7.23% of their portfolio Greenwich, CT 513,700513.7k $37.5m $37.5m 7.23% Unchanged
69 TD Asset Management Inc 0.03% of their portfolio Toronto, A6 513,082513.1k $37.2m $37.2m 0.03% Reduced -12.6k -12,600
70 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.09% of their portfolio Paris, I0 509,439509.4k $37.2m $37.2m 0.09% Reduced -144.9k -144,909
71 Cormorant Asset Management, LP 1.94% of their portfolio BOSTON, MA 500,000500.0k $36.5m $36.5m 1.94% Reduced -175.0k -175,000
72 Qube Research & Technologies Ltd 0.07% of their portfolio LONDON, X0 489,307489.3k $35.7m $35.7m 0.07% New
73 EMERALD MUTUAL FUND ADVISERS TRUST 1.85% of their portfolio LEOLA, PA 487,664487.7k $35.6m $35.6m 1.85% Reduced -6.2k -6,185
74 Squarepoint Ops LLC 0.12% of their portfolio NEW YORK, NY 485,618485.6k $35.5m $35.5m 0.12% Added +435.1k +435,071
75 Ensign Peak Advisors, Inc 0.06% of their portfolio SALT LAKE CITY, UT 484,121484.1k $35.3m $35.3m 0.06% Added +125.1k +125,092
76 TimesSquare Capital Management, LLC 0.53% of their portfolio NEW YORK, NY 483,869483.9k $35.3m $35.3m 0.53% New
77 SOROS FUND MANAGEMENT LLC 0.70% of their portfolio NEW YORK, NY 478,601478.6k $34.9m $34.9m 0.70% Added +7.9k +7,901
78 Candriam S.C.A. 0.20% of their portfolio STRASSEN, N4 476,494476.5k $34.8m $34.8m 0.20% Reduced -79.4k -79,440
79 VICTORY CAPITAL MANAGEMENT INC 0.03% of their portfolio San Antonio, TX 455,959456.0k $33.3m $33.3m 0.03% Added +308.8k +308,819
80 FRED ALGER MANAGEMENT, LLC 0.16% of their portfolio NEW YORK, NY 452,316452.3k $33.0m $33.0m 0.16% Reduced -46.3k -46,256
81 Octagon Capital Advisors LP 5.10% of their portfolio NEW YORK, NY 436,820436.8k $31.9m $31.9m 5.10% Reduced -213.4k -213,396
82 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 422,936422.9k $30.9m $30.9m 0.01% Reduced -14.3k -14,319
83 KINGDON CAPITAL MANAGEMENT, L.L.C. 4.29% of their portfolio NEW YORK, NY 400,000400.0k $29.2m $29.2m 4.29% Reduced -225.0k -225,000
84 GROUPAMA ASSET MANAGMENT 0.02% of their portfolio PARIS, I0 400,000400.0k $739.4k $739.4k 0.02% New
85 TWO SIGMA ADVISERS, LP 0.07% of their portfolio NEW YORK, NY 392,700392.7k $28.7m $28.7m 0.07% Added +97.3k +97,300
86 Allspring Global Investments Holdings, LLC 0.04% of their portfolio CHARLOTTE, NC 390,134390.1k $28.5m $28.5m 0.04% Added +62.1k +62,061
87 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 367,252367.3k $26.8m $26.8m 0.01% Added +355.2k +355,163
88 First Turn Management, LLC 4.12% of their portfolio DEL MAR, CA 356,451356.5k $26.0m $26.0m 4.12% Added +33.1k +33,091
89 SILVERARC CAPITAL MANAGEMENT, LLC 5.72% of their portfolio BOSTON, MA 347,695347.7k $25.4m $25.4m 5.72% Added +207.7k +207,695
90 C WorldWide Group Holding A/S 0.26% of their portfolio COPENHAGEN, G7 343,110343.1k $25.0m $25.0m 0.26% Unchanged
91 CITADEL ADVISORS LLC 0.03% of their portfolio MIAMI, FL 336,562336.6k $24.6m $24.6m 0.03% Reduced -463.2k -463,184
92 SEI INVESTMENTS CO 0.03% of their portfolio OAKS, PA 333,597333.6k $24.4m $24.4m 0.03% Added +55.9k +55,885
93 BARCLAYS PLC 0.01% of their portfolio LONDON, X0 332,063332.1k $24.2m $24.2m 0.01% Added +223.5k +223,468
94 BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio PARIS, I0 316,876316.9k $23.1m $23.1m 0.02% Added +255.3k +255,268
95 Point72 Asset Management, L.P. 0.08% of their portfolio STAMFORD, CT 315,151315.2k $23.0m $23.0m 0.08% Reduced -543.1k -543,149
96 UBS Group AG 0.01% of their portfolio ZURICH, V8 309,992310.0k $22.6m $22.6m 0.01% Added +76.0k +76,003
97 Swiss National Bank 0.01% of their portfolio ZURICH, V8 302,500302.5k $22.1m $22.1m 0.01% Added +25.0k +25,000
98 NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio ALBANY, NY 292,779292.8k $21.4m $21.4m 0.03% Reduced -29.5k -29,520
99 PANAGORA ASSET MANAGEMENT INC 0.10% of their portfolio BOSTON, MA 290,470290.5k $21.2m $21.2m 0.10% Reduced -65.7k -65,665
100 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.02% of their portfolio Toronto, A6 288,073288.1k $21.0m $21.0m 0.02% Added +5.1k +5,062