Vault-13

INSMED INC INSM

COM PAR $.01 · Common Stock · CUSIP 457669307 · ISIN US4576693075

290 institutional holders +17 vs Q4 2023
152,124,761152.1m shares reported held*
102.4% of all shares outstanding*
$4.1bnreported value*
44 new 97 added 97 reduced 29 sold out net bought ≈ $5.9m (+216.8k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($6.4m this quarter). Holder counts are more reliable. Shares outstanding: 148.6m as of 2024-05-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $27.13. Options: 31 managers hold calls ($68.3m notional), 20 hold puts ($84.5m).

Trends to Q1 2024

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 239Q4 22: 226Q1 23: 232Q2 23: 225Q3 23: 254Q4 23: 273Q1 24: 290290Q3 22Q1 23Q3 23Q1 24
Numbers
QuarterHolders
Q3 2022239
Q4 2022226
Q1 2023232
Q2 2023225
Q3 2023254
Q4 2023273
Q1 2024290

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 132 bought or addedQ4 22: 104 cut or sold outQ4 22Q1 23: 123 bought or addedQ1 23: 97 cut or sold outQ1 23Q2 23: 103 bought or addedQ2 23: 111 cut or sold outQ2 23Q3 23: 133 bought or addedQ3 23: 95 cut or sold outQ3 23Q4 23: 131 bought or addedQ4 23: 111 cut or sold outQ4 23Q1 24: 141 bought or addedQ1 24: 126 cut or sold outQ1 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022132104
Q1 202312397
Q2 2023103111
Q3 202313395
Q4 2023131111
Q1 2024141126

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25m$50m$75m$100mQ2 23 calls: $9.7mQ2 23 puts: $13.7mQ2 23P/C 1.41Q3 23 calls: $9.3mQ3 23 puts: $40.6mQ3 23P/C 4.38Q4 23 calls: $10.0mQ4 23 puts: $52.2mQ4 23P/C 5.19Q1 24 calls: $68.3mQ1 24 puts: $84.5mQ1 24P/C 1.24
Numbers
QuarterCallsPutsP/C
Q2 2023$9.7m$13.7m1.41
Q3 2023$9.3m$40.6m4.38
Q4 2023$10.0m$52.2m5.19
Q1 2024$68.3m$84.5m1.24

Biggest buyers

FMR LLC Added +4,227,280+4.2m
Capital International Investors New +1,620,814+1.6m
FIRST TRUST ADVISORS LP Added +1,341,242+1.3m
Integral Health Asset Management, LLC Added +950,000+950.0k
Clearbridge Investments, LLC New +930,409+930.4k
Assenagon Asset Management S.A. Added +927,040+927.0k
JANUS HENDERSON GROUP PLC Added +826,372+826.4k
FRONTIER CAPITAL MANAGEMENT CO LLC New +747,331+747.3k
GREAT POINT PARTNERS LLC Added +549,673+549.7k
AMERIPRISE FINANCIAL INC Added +452,847+452.8k

Biggest sellers

T. Rowe Price Investment Management, Inc. Reduced -2,399,026-2.4m
Holocene Advisors, LP Sold out -1,614,862-1.6m
MILLENNIUM MANAGEMENT LLC Reduced -1,328,383-1.3m
Palo Alto Investors LP Reduced -1,088,352-1.1m
LOOMIS SAYLES & CO L P Reduced -839,711-839.7k
MACQUARIE GROUP LTD Reduced -751,988-752.0k
SAMLYN CAPITAL, LLC Reduced -699,234-699.2k
MONTANOVA CAPITAL, LLC Reduced -661,487-661.5k
Deep Track Capital, LP Reduced -566,321-566.3k
Balyasny Asset Management L.P. Reduced -493,037-493.0k

Biggest calls

Integral Health Asset Management, LLC New $13.6m500.0k shares
Ikarian Capital, LLC Added $9.4m347.2k shares
KINGDON CAPITAL MANAGEMENT, L.L.C. New $5.4m200.0k shares
JANE STREET GROUP, LLC Added $4.7m174.7k shares
CITIGROUP INC Added $4.2m155.6k shares
BOOTHBAY FUND MANAGEMENT, LLC New $3.8m139.2k shares
LMR Partners LLP Added $3.0m110.4k shares
J. Goldman & Co LP New $2.7m101.0k shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC New $2.7m100.1k shares
Sofinnova Investments, Inc. New $2.7m100.0k shares

Biggest puts

Sio Capital Management, LLC Added $37.0m1.4m shares
Caption Management, LLC Added $16.5m609.7k shares
Balyasny Asset Management L.P. Reduced $14.5m533.1k shares
CITADEL ADVISORS LLC Added $3.5m128.3k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $2.1m76.8k shares
Ikarian Capital, LLC New $1.9m70.9k shares
Point72 Asset Management, L.P. Unchanged $1.6m59.2k shares
Hudson Bay Capital Management LP Unchanged $1.4m50.0k shares
BOOTHBAY FUND MANAGEMENT, LLC New $1.4m49.9k shares
WOLVERINE TRADING, LLC Added $1.1m41.8k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 7.4% +1.3 pts 16.1m≈ $1.7bn 2026-08-06
BlackRock, Inc. 13G · institution +1.5 pts · filed 2026-01-21 6.6% +1.5 pts 14.1m≈ $1.5bn 2026-01-21
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.3% new 11.5m≈ $1.2bn 2026-04-30

Fell to 5% or below in the last year: Darwin Global Management, Ltd. (3.0%, 2026-08-14), JPMORGAN CHASE & CO (4.7%, 2026-07-22), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), PRICE T ROWE ASSOCIATES INC /MD/ (3.3%, 2025-11-14)

Insider purchases and sales in Q1 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q2 22: 1 buyingQ2 22: 6 sellingQ3 22: 0 buyingQ3 22: 3 sellingQ3 22Q4 22: 2 buyingQ4 22: 2 sellingQ1 23: 0 buyingQ1 23: 7 sellingQ1 23Q2 23: 1 buyingQ2 23: 7 sellingQ3 23: 0 buyingQ3 23: 1 sellingQ3 23Q4 23: 0 buyingQ4 23: 4 sellingQ1 24: 0 buyingQ1 24: 7 sellingQ1 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20221$344.0k6$389.7k—
Q3 20220—3$8.3m—
Q4 20222$1.3m2$357.7k—
Q1 20230—7$679.5k—
Q2 20231$385.8k7$1.2m$344.4k
Q3 20230—1$14.9k—
Q4 20230—4$4.7m$4.7m
Q1 20240—7$3.7m$3.0m
DateInsiderTradeSharesPrice ValueTheir holding
2024-01-12 Adsett Roger Chief Operating Officer Sold plan 5,251 $28.63 $150.3k5.3k shares -3%
2024-01-12 Flammer Martina M.D. Chief Medical Officer Sold plan 4,667 $28.63 $133.6k4.7k shares -4%
2024-01-10 Adsett Roger Chief Operating Officer Sold plan 3,536 $28.90 $102.2k3.5k shares -2%
2024-01-10 Flammer Martina M.D. Chief Medical Officer Sold plan 1,245 $28.90 $36.0k1.2k shares -1%
2024-01-09 Lewis William Chair and CEO, director Sold plan 9,887 $28.72 $284.0k9.9k shares -3%
2024-01-09 Flammer Martina M.D. Chief Medical Officer Sold plan 4,715 $29.01 $136.8k4.7k shares -4%
2024-01-09 Bonstein Sara Chief Financial Officer Sold 4,497 $29.18 $131.2k4.5k shares -4%
2024-01-09 Adsett Roger Chief Operating Officer Sold plan 3,837 $29.25 $112.2k3.8k shares -2%
2024-01-09 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold plan 3,668 $28.85 $105.8k3.7k shares -4%
2024-01-09 Smith Michael Alexander General Counsel, Senior VP Sold 2,373 $28.76 $68.2k2.4k shares -3%
2024-01-09 Wise John Drayton Chief Commercial Officer Sold 1,861 $28.78 $53.6k1.9k shares -2%
2024-01-08 Lewis William Chair and CEO, director Sold plan 45,120 $29.45 $1.3m45.1k shares -11%
2024-01-05 Lewis William Chair and CEO, director Sold 6,979 $29.26 $204.2k7.0k shares -2%
2024-01-05 Adsett Roger Chief Operating Officer Sold 3,042 $29.21 $88.9k3.0k shares -2%
2024-01-05 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold 1,457 $29.28 $42.7k1.5k shares -1%
2024-01-05 Flammer Martina M.D. Chief Medical Officer Sold 1,386 $29.21 $40.5k1.4k shares -1%
2024-01-05 Wise John Drayton Chief Commercial Officer Sold plan 1,167 $29.32 $34.2k1.2k shares -1%
2024-01-05 Smith Michael Alexander General Counsel, Senior VP Sold 627 $29.31 $18.4k627 shares -1%
2024-01-03 Wise John Drayton Chief Commercial Officer · Stock Option (right to buy) Sold plan 20,071 $29.19 $585.9k20.1k shares -16%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q1 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.01% of their portfolio Valley Forge, PA 14,509,23514.5m $393.6m $393.6m 0.01% Added +383.7k +383,714
2 BlackRock Inc. 0.01% of their portfolio New York, NY 11,799,70111.8m $320.1m $320.1m 0.01% Added +307.4k +307,419
3 PRICE T ROWE ASSOCIATES INC /MD/ 0.04% of their portfolio BALTIMORE, MD 10,769,36610.8m $292.2m $292.2m 0.04% Added +5.6k +5,595
4 FMR LLC 0.02% of their portfolio BOSTON, MA 9,318,8949.3m $252.8m $252.8m 0.02% Added +4.2m +4,227,280
5 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 5,905,1275.9m $160.2m $160.2m 0.01% Reduced -24.8k -24,806
6 Deep Track Capital, LP 3.73% of their portfolio GREENWICH, CT 4,783,6794.8m $129.8m $129.8m 3.73% Reduced -566.3k -566,321
7 Palo Alto Investors LP 13.53% of their portfolio PALO ALTO, CA 4,423,3694.4m $120.0m $120.0m 13.53% Reduced -1.1m -1,088,352
8 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.30% of their portfolio CHICAGO, IL 4,214,7194.2m $114.3m $114.3m 0.30% Reduced -42.0k -41,968
9 MACQUARIE GROUP LTD 0.12% of their portfolio Sydney, NSW 2000, C3 3,899,5043.9m $105.8m $105.8m 0.12% Reduced -752.0k -751,988
10 FRANKLIN RESOURCES INC 0.03% of their portfolio San Mateo, CA 3,567,0133.6m $96.8m $96.8m 0.03% Added +170.3k +170,286
11 T. Rowe Price Investment Management, Inc. 0.06% of their portfolio BALTIMORE, MD 3,451,5803.5m $93.6m $93.6m 0.06% Reduced -2.4m -2,399,026
12 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 3,163,7513.2m $85.8m $85.8m 0.01% Added +94.4k +94,373
13 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 2,818,8092.8m $76.5m $76.5m 0.00% Reduced -250.7k -250,685
14 AMERIPRISE FINANCIAL INC 0.02% of their portfolio MINNEAPOLIS, MN 2,735,3382.7m $74.2m $74.2m 0.02% Added +452.8k +452,847
15 JANUS HENDERSON GROUP PLC 0.03% of their portfolio LONDON, X0 2,229,4632.2m $60.5m $60.5m 0.03% Added +826.4k +826,372
16 ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio NASHVILLE, TN 2,146,4792.1m $58.2m $58.2m 0.02% Reduced -1.4k -1,423
17 Bellevue Group AG 0.89% of their portfolio ZURICH, V8 2,141,8432.1m $58.1m $58.1m 0.89% Reduced -149.1k -149,115
18 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 2,051,3112.1m $55.7m $55.7m 0.01% Reduced -305.6k -305,551
19 MONTANOVA CAPITAL, LLC 2.32% of their portfolio New York, NY 2,023,0002.0m $54.9m $54.9m 2.32% Reduced -661.5k -661,487
20 RTW INVESTMENTS, LP 0.75% of their portfolio NEW YORK, NY 1,865,1081.9m $50.6m $50.6m 0.75% Unchanged
21 Capital International Investors 0.01% of their portfolio Los Angeles, CA 1,620,8141.6m $44.0m $44.0m 0.01% New
22 NORGES BANK 0.01% of their portfolio OSLO, Q8 1,588,5411.6m $43.1m $43.1m 0.01% Added +135.5k +135,516
23 Pictet Asset Management Holding SA 0.05% of their portfolio CAROUGE, V8 1,530,0081.5m $41.5m $41.5m 0.05% Reduced -431.8k -431,793
24 LOOMIS SAYLES & CO L P 0.06% of their portfolio BOSTON, MA 1,491,7941.5m $40.5m $40.5m 0.06% Reduced -839.7k -839,711
25 PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio DES MOINES, IA 1,439,2801.4m $39.0m $39.0m 0.02% Added +79.7k +79,717
26 FIRST TRUST ADVISORS LP 0.04% of their portfolio Wheaton, IL 1,437,1741.4m $39.0m $39.0m 0.04% Added +1.3m +1,341,242
27 NOVO HOLDINGS A/S 2.51% of their portfolio HELLERUP, G7 1,339,3041.3m $36.3m $36.3m 2.51% Unchanged
28 NORTHERN TRUST CORP 0.01% of their portfolio CHICAGO, IL 1,336,7971.3m $36.3m $36.3m 0.01% Reduced -35.4k -35,448
29 MARSHALL WACE, LLP 0.06% of their portfolio LONDON, X0 1,330,0481.3m $36.1m $36.1m 0.06% Reduced -109.7k -109,721
30 Integral Health Asset Management, LLC 3.46% of their portfolio New York, NY 1,300,0001.3m $35.3m $35.3m 3.46% Added +950.0k +950,000
31 GW&K Investment Management, LLC 0.30% of their portfolio BOSTON, MA 1,269,8981.3m $34.5m $34.5m 0.30% Reduced -21.9k -21,874
32 Assenagon Asset Management S.A. 0.09% of their portfolio SENNINGERBERG, N4 1,211,5601.2m $32.9m $32.9m 0.09% Added +927.0k +927,040
33 Octagon Capital Advisors LP 3.76% of their portfolio NEW YORK, NY 1,140,0001.1m $30.9m $30.9m 3.76% Reduced -144.0k -144,000
34 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 1,126,7671.1m $30.6m $30.6m 0.01% Reduced -1.7k -1,669
35 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 996,128996.1k $27.0m $27.0m 0.00% Reduced -47.7k -47,703
36 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.07% of their portfolio Paris, I0 972,313972.3k $26.4m $26.4m 0.07% Added +76.4k +76,367
37 Hood River Capital Management LLC 0.58% of their portfolio PALM BEACH GARDENS, FL 962,501962.5k $26.1m $26.1m 0.58% Added +56.7k +56,682
38 Clearbridge Investments, LLC 0.02% of their portfolio NEW YORK, NY 930,409930.4k $25.2m $25.2m 0.02% New
39 CITADEL ADVISORS LLC 0.02% of their portfolio MIAMI, FL 927,563927.6k $25.2m $25.2m 0.02% Reduced -118.7k -118,651
40 GREAT POINT PARTNERS LLC 3.28% of their portfolio Greenwich, CT 775,585775.6k $21.0m $21.0m 3.28% Added +549.7k +549,673
41 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 753,610753.6k $20.4m $20.4m 0.00% Reduced -8.2k -8,162
42 Vestal Point Capital, LP 1.68% of their portfolio NEW YORK, NY 750,000750.0k $20.3m $20.3m 1.68% Reduced -150.0k -150,000
43 FRONTIER CAPITAL MANAGEMENT CO LLC 0.19% of their portfolio Boston, MA 747,331747.3k $20.3m $20.3m 0.19% New
44 FIL Ltd 0.02% of their portfolio HAMILTON, D0 720,245720.2k $19.5m $19.5m 0.02% Added +28.8k +28,814
45 TWO SIGMA ADVISERS, LP 0.05% of their portfolio NEW YORK, NY 716,400716.4k $19.4m $19.4m 0.05% Added +87.2k +87,200
46 AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio KANSAS CITY, MO 702,624702.6k $19.1m $19.1m 0.01% Added +40.4k +40,424
47 EVENTIDE ASSET MANAGEMENT, LLC 0.27% of their portfolio Boston, MA 635,185635.2k $17.2m $17.2m 0.27% Unchanged
48 EMERALD ADVISERS, LLC 0.69% of their portfolio LEOLA, PA 630,179630.2k $17.1m $17.1m 0.69% Reduced -300.7k -300,670
49 Hudson Bay Capital Management LP 0.15% of their portfolio STAMFORD, CT 626,810626.8k $17.0m $17.0m 0.15% Added +159.3k +159,310
50 SAMLYN CAPITAL, LLC 0.28% of their portfolio New York, NY 587,634587.6k $15.9m $15.9m 0.28% Reduced -699.2k -699,234
51 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 579,062579.1k $15.7m $15.7m 0.00% Reduced -185.9k -185,926
52 Cormorant Asset Management, LP 0.69% of their portfolio BOSTON, MA 575,000575.0k $15.6m $15.6m 0.69% Unchanged
53 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 537,231537.2k $14.6m $14.6m 0.00% Added +160.0k +160,016
54 MPM BIOIMPACT LLC 2.33% of their portfolio BOSTON, MA 530,794530.8k $14.4m $14.4m 2.33% Added +2.6k +2,644
55 EAGLE ASSET MANAGEMENT INC 0.07% of their portfolio ST PETERSBURG, FL 524,372524.4k $14.0m $14.0m 0.07% Reduced -24.3k -24,261
56 PANAGORA ASSET MANAGEMENT INC 0.07% of their portfolio BOSTON, MA 514,829514.8k $14.0m $14.0m 0.07% Added +85.8k +85,826
57 EMERALD MUTUAL FUND ADVISERS TRUST 0.68% of their portfolio LEOLA, PA 484,714484.7k $13.2m $13.2m 0.68% Reduced -263.6k -263,630
58 VOYA INVESTMENT MANAGEMENT LLC 0.01% of their portfolio ATLANTA, GA 472,006472.0k $12.8m $12.8m 0.01% Reduced -32.2k -32,231
59 TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio NEW YORK, NY 460,173460.2k $12.5m $12.5m 0.03% Added +107.6k +107,561
60 KINGDON CAPITAL MANAGEMENT, L.L.C. 1.63% of their portfolio NEW YORK, NY 455,000455.0k $12.3m $12.3m 1.63% Reduced -355.0k -355,000
61 Cutter Capital Management, LP 2.38% of their portfolio NEW YORK, NY 454,674454.7k $12.3m $12.3m 2.38% Added +41.2k +41,175
62 Balyasny Asset Management L.P. 0.03% of their portfolio Chicago, IL 450,394450.4k $12.2m $12.2m 0.03% Reduced -493.0k -493,037
63 Long Focus Capital Management, LLC 1.35% of their portfolio SAN JUAN, PR 431,649431.6k $11.7m $11.7m 1.35% Added +60.0k +60,000
64 TD Asset Management Inc 0.01% of their portfolio Toronto, A6 427,178427.2k $11.6m $11.6m 0.01% Reduced -36.4k -36,354
65 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 407,025407.0k $11.0m $11.0m 0.00% Reduced -545 -545
66 Candriam S.C.A. 0.07% of their portfolio STRASSEN, N4 390,200390.2k $10.6m $10.6m 0.07% Added +80.0k +80,000
67 UBS Group AG 0.00% of their portfolio ZURICH, V8 381,063381.1k $10.3m $10.3m 0.00% Added +80.9k +80,882
68 Schonfeld Strategic Advisors LLC 0.08% of their portfolio NEW YORK, NY 369,918369.9k $10.0m $10.0m 0.08% Added +290.5k +290,544
69 C WorldWide Group Holding A/S 0.11% of their portfolio COPENHAGEN, G7 343,110343.1k $9.3m $9.3m 0.11% Unchanged
70 BAKER BROS. ADVISORS LP 0.12% of their portfolio NEW YORK, NY 343,000343.0k $9.3m $9.3m 0.12% Unchanged
71 Ensign Peak Advisors, Inc 0.02% of their portfolio SALT LAKE CITY, UT 341,574341.6k $9.3m $9.3m 0.02% Added +271.6k +271,564
72 Rafferty Asset Management, LLC 0.03% of their portfolio New York, NY 329,635329.6k $8.9m $8.9m 0.03% Added +8.5k +8,548
73 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 326,566326.6k $8.9m $8.9m 0.01% Added +183.3k +183,285
74 Bleichroeder LP 2.20% of their portfolio NEW YORK, NY 325,000325.0k $8.8m $8.8m 2.20% Unchanged
75 WCM INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio LAGUNA BEACH, CA 320,001320.0k $8.7m $8.7m 0.02% Added +24.7k +24,673
76 PEREGRINE CAPITAL MANAGEMENT LLC 0.23% of their portfolio MINNEAPOLIS, MN 290,174290.2k $7.9m $7.9m 0.23% Added +86 +86
77 AXA S.A. 0.02% of their portfolio PARIS, I0 288,599288.6k $7.8m $7.8m 0.02% Reduced -415.5k -415,493
78 First Light Asset Management, LLC 0.59% of their portfolio Edina, MN 282,766282.8k $7.7m $7.7m 0.59% Reduced -363.3k -363,291
79 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 276,618276.6k $7.5m $7.5m 0.01% Reduced -1.3m -1,328,383
80 SCOUT INVESTMENTS, INC. 0.18% of their portfolio KANSAS CITY, MO 275,670275.7k $7.4m $7.4m 0.18% Reduced -17.5k -17,527
81 STEMPOINT CAPITAL LP 1.97% of their portfolio NEW YORK, NY 272,448272.4k $7.4m $7.4m 1.97% Added +98.9k +98,869
82 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 270,973271.0k $7.4m $7.4m 0.01% Added +158.0k +157,999
83 Swiss National Bank 0.01% of their portfolio ZURICH, V8 268,400268.4k $7.3m $7.3m 0.01% Reduced -800 -800
84 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 254,560254.6k $6.9m $6.9m 0.00% Added +90.3k +90,328
85 Polar Capital Holdings Plc 0.04% of their portfolio London, X0 251,700251.7k $6.8m $6.8m 0.04% Reduced -252.6k -252,575
86 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 250,000250.0k $6.8m $6.8m 0.01% Reduced -350.0k -350,000
87 Soleus Capital Management, L.P. 0.60% of their portfolio GREENWICH, CT 250,000250.0k $6.8m $6.8m 0.60% Added +82.9k +82,900
88 Ally Bridge Group (NY) LLC 3.77% of their portfolio NEW YORK, NY 250,000250.0k $6.8m $6.8m 3.77% New
89 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 239,984240.0k $6.5m $6.5m 0.01% Added +18.4k +18,412
90 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio Toronto, A6 232,681232.7k $6.3m $6.3m 0.01% Added +20.6k +20,646
91 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 227,936227.9k $6.2m $6.2m 0.00% Reduced -106.6k -106,593
92 RHUMBLINE ADVISERS 0.01% of their portfolio BOSTON, MA 207,662207.7k $5.6m $5.6m 0.01% Added +4.0k +3,966
93 Alyeska Investment Group, L.P. 0.03% of their portfolio CHICAGO, IL 200,000200.0k $5.4m $5.4m 0.03% New
94 Walleye Capital LLC 0.06% of their portfolio NEW YORK, NY 191,142191.1k $5.2m $5.2m 0.06% Added +72.7k +72,731
95 California Public Employees Retirement System 0.00% of their portfolio Sacramento, CA 190,717190.7k $5.2m $5.2m 0.00% Reduced -588 -588
96 RICE HALL JAMES & ASSOCIATES, LLC 0.28% of their portfolio San Diego, CA 179,332179.3k $4.9m $4.9m 0.28% Reduced -41.9k -41,938
97 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 174,022174.0k $4.7m $4.7m 0.01% Reduced -472.9k -472,885
98 NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio NEW YORK, NY 170,917170.9k $4.6m $4.6m 0.00% Added +2.0k +1,989
99 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 167,563167.6k $4.5m $4.5m 0.00% Added +66.0k +66,039
100 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.21% of their portfolio BALA CYNWYD, PA 166,409166.4k $4.5m $4.5m 0.21% New