INCYTE CORP INCY
COM · Common Stock · CUSIP 45337C102 · ISIN US45337C1027
American pharmaceutical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, DE
- Founded2001
- Websiteincyte.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($23.6m this quarter). Holder counts are more reliable. Shares outstanding: 192.7m as of 2024-10-22, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $65.48. Options: 21 managers hold calls ($49.9m notional), 18 hold puts ($43.0m).
Trends to Q3 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 537 |
| Q4 2022 | 558 |
| Q1 2023 | 552 |
| Q2 2023 | 529 |
| Q3 2023 | 531 |
| Q4 2023 | 558 |
| Q1 2024 | 587 |
| Q2 2024 | 586 |
| Q3 2024 | 595 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 265 | 251 |
| Q1 2023 | 313 | 230 |
| Q2 2023 | 238 | 287 |
| Q3 2023 | 298 | 212 |
| Q4 2023 | 268 | 257 |
| Q1 2024 | 295 | 255 |
| Q2 2024 | 292 | 288 |
| Q3 2024 | 244 | 332 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2023 | $57.8m | $27.6m | 0.48 |
| Q1 2024 | $23.6m | $37.9m | 1.61 |
| Q2 2024 | $51.7m | $42.3m | 0.82 |
| Q3 2024 | $49.9m | $43.0m | 0.86 |
Biggest buyers
| Point72 Asset Management, L.P. | New | +2.4m |
| MIZUHO SECURITIES USA LLC | Added | +2.0m |
| MARSHALL WACE, LLP | Added | +1.2m |
| Sofinnova Investments, Inc. | New | +714.2k |
| JUPITER ASSET MANAGEMENT LTD | New | +701.5k |
| Sound Shore Management Inc /CT/ | New | +605.3k |
| ARMISTICE CAPITAL, LLC | Added | +432.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +383.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Added | +364.2k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Added | +352.9k |
Biggest sellers
| Pacer Advisors, Inc. | Reduced | -2.7m |
| ACADIAN ASSET MANAGEMENT LLC | Reduced | -1.6m |
| JANE STREET GROUP, LLC | Reduced | -1.3m |
| Squarepoint Ops LLC | Reduced | -1.3m |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -718.8k |
| APG Asset Management N.V. | Reduced | -636.1k |
| CANADA PENSION PLAN INVESTMENT BOARD | Reduced | -586.9k |
| KBC Group NV | Reduced | -563.4k |
| Connor, Clark & Lunn Investment Management Ltd. | Reduced | -547.9k |
| Candriam S.C.A. | Reduced | -509.9k |
Biggest calls
| LMR Partners LLP | Reduced | $10.7m161.2k shares |
| BANK OF AMERICA CORP /DE/ | New | $9.9m150.0k shares |
| CITADEL ADVISORS LLC | Added | $7.6m114.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $5.6m84.0k shares |
| JANE STREET GROUP, LLC | Added | $3.0m45.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.1m31.7k shares |
| GOLDMAN SACHS GROUP INC | Reduced | $1.8m26.9k shares |
| Parallax Volatility Advisers, L.P. | New | $1.6m24.9k shares |
| GROUP ONE TRADING LLC | Reduced | $1.3m19.7k shares |
| WOLVERINE TRADING, LLC | Added | $1.2m18.4k shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $9.4m142.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $8.8m133.8k shares |
| JANE STREET GROUP, LLC | Added | $5.2m78.0k shares |
| Parallax Volatility Advisers, L.P. | New | $4.7m71.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.5m37.6k shares |
| GROUP ONE TRADING LLC | Added | $2.0m30.6k shares |
| GOLDMAN SACHS GROUP INC | Unchanged | $1.8m26.9k shares |
| WOLVERINE TRADING, LLC | Added | $1.8m26.8k shares |
| IMC-Chicago, LLC | Reduced | $1.7m25.1k shares |
| Squarepoint Ops LLC | New | $1.0m15.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-0.1 pts · filed 2026-05-11
Stated purposeItem 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows: On May 8, 2026 the Adviser acquired beneficial ownership of 15,000 shares of common stock ("Common Stock") of Incyte Corporation (the "Issuer"), as a result of the exercise of 15,000 options to purchase Common Stock at $84.53 per share (the "Exercised Stock Options") held directly by Julian C. Baker. Julian C. Baker currently serves on the Issuer's board of directors (the "Board") as a representative of the Funds. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in the Exercised Stock Options. Julian C… Full filing |
15.6% |
| BlackRock, Inc. 13G · institution filed 2025-10-17 | 7.8% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 6.3% |
| DODGE & COX 13G · institution filed 2026-05-14 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q3 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Q1 2023 | 0 | — | 4 | $8.2m | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 2 | $1.9m | $1.4m |
| Q4 2023 | 0 | — | 1 | $78.6k | $78.6k |
| Q1 2024 | 0 | — | 2 | $525.2k | $525.2k |
| Q2 2024 | 0 | — | 2 | $1.2m | $1.2m |
| Q3 2024 | 0 | — | 5 | $3.0m | $3.0m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-09-13 | Tray Thomas Principal Accounting Officer | Sold plan | $24.2k382 shares |
| 2024-09-12 | Dickinson Jonathan Elliott EVP, General Manager, Europe | Sold plan | $526.9k8.4k shares |
| 2024-09-12 | Tray Thomas Principal Accounting Officer | Sold plan | $36.0k572 shares |
| 2024-08-12 | Stein Steven H EVP & Chief Medical Officer | Sold plan | $703.8k11.6k shares |
| 2024-07-25 | Iyengar Vijay K EVP, GMAPPS | Sold plan | $1.1m15.6k shares |
| 2024-07-16 | Flannelly Barry P EVP & General Manager US | Sold plan | $83.8k1.3k shares |
| 2024-07-09 | Flannelly Barry P EVP & General Manager US | Sold plan | $488.9k8.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2024
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 21.06% of their portfolio | 30.7m $2.0bn | Added +496 |
| VANGUARD GROUP INC 0.02% of their portfolio | 20.4m $1.3bn | Added +7.3k |
| BlackRock, Inc. 0.02% of their portfolio | 17.1m $1.1bn | First filing |
| Dodge & Cox 0.57% of their portfolio | 15.3m $1.0bn | Reduced -3.2k |
| STATE STREET CORP 0.03% of their portfolio | 10.6m $697.4m | Reduced -300.2k |
| RENAISSANCE TECHNOLOGIES LLC 0.45% of their portfolio | 4.5m $297.4m | Reduced -718.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 3.9m $259.3m | Reduced -110.5k |
| Invesco Ltd. 0.05% of their portfolio | 3.6m $236.3m | Added +5.1k |
| LSV ASSET MANAGEMENT 0.41% of their portfolio | 2.9m $193.2m | Added +153.5k |
| AQR CAPITAL MANAGEMENT LLC 0.25% of their portfolio | 2.7m $178.6m | Added +40.0k |
| Point72 Asset Management, L.P. 0.55% of their portfolio | 2.4m $156.6m | New |
| ARMISTICE CAPITAL, LLC 3.80% of their portfolio | 2.2m $145.2m | Added +432.1k |
| Bellevue Group AG 2.30% of their portfolio | 2.2m $142.2m | Reduced -3.0k |
| MORGAN STANLEY 0.01% of their portfolio | 2.1m $141.9m | Reduced -108.2k |
| MIZUHO SECURITIES USA LLC 0.24% of their portfolio | 2.0m $22.1m | Added +2.0m |
| ACADIAN ASSET MANAGEMENT LLC 0.41% of their portfolio | 2.0m $132.3m | Reduced -1.6m |
| NORGES BANK 0.02% of their portfolio | 1.7m $111.3m | Reduced -441.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 1.6m $106.4m | Added +364.2k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 1.5m $102.2m | Reduced -267.7k |
| Legal & General Group Plc 0.03% of their portfolio | 1.5m $98.1m | Reduced -55.1k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 1.4m $93.4m | Added +231.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio | 1.4m $91.2m | Reduced -438.8k |
| FMR LLC 0.01% of their portfolio | 1.3m $87.3m | Reduced -466.9k |
| MARSHALL WACE, LLP 0.11% of their portfolio | 1.3m $84.5m | Added +1.2m |
| Robeco Institutional Asset Management B.V. 0.17% of their portfolio | 1.3m $83.7m | Added +70.6k |
| HSBC HOLDINGS PLC 0.05% of their portfolio | 1.2m $82.4m | Added +6.0k |
| KBC Group NV 0.23% of their portfolio | 1.2m $76.7m | Reduced -563.4k |
| FIRST TRUST ADVISORS LP 0.07% of their portfolio | 1.1m $75.7m | Reduced -99.4k |
| D. E. Shaw & Co., Inc. 0.10% of their portfolio | 1.1m $73.3m | Reduced -124.6k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 1.0m $69.3m | Reduced -99.3k |
| BARCLAYS PLC 0.03% of their portfolio | 1.0m $68.2m | Added +137.5k |
| DEUTSCHE BANK AG\ 0.03% of their portfolio | 959.0k $63.4m | Added +161.0k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 873.5k $57.7m | Reduced -75.3k |
| California Public Employees Retirement System 0.04% of their portfolio | 819.2k $54.1m | Reduced -89.4k |
| Candriam S.C.A. 0.31% of their portfolio | 809.7k $53.5m | Reduced -509.9k |
| Man Group plc 0.15% of their portfolio | 805.0k $53.2m | Added +18.4k |
| Woodline Partners LP 0.44% of their portfolio | 794.8k $52.5m | Reduced -359.4k |
| CITADEL ADVISORS LLC 0.05% of their portfolio | 781.3k $51.6m | Reduced -40.4k |
| Pictet Asset Management Holding SA 0.05% of their portfolio | 757.7k $49.9m | Added +4.9k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 743.0k $49.1m | Reduced -24.1k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.17% of their portfolio | 726.9k $48.0m | Added +352.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 724.9k $47.9m | Added +6.2k |
| Sofinnova Investments, Inc. 3.91% of their portfolio | 714.2k $47.2m | New |
| JUPITER ASSET MANAGEMENT LTD 0.41% of their portfolio | 701.5k $46.4m | New |
| GLENMEDE TRUST CO NA 0.22% of their portfolio | 697.0k $46.1m | Reduced -157.0k |
| Swedbank AB 0.06% of their portfolio | 666.1k $44.0m | Reduced -66 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 608.4k $40.2m | Added +383.3k |
| FEDERATED HERMES, INC. 0.09% of their portfolio | 607.1k $40.1m | Reduced -251.0k |
| Sound Shore Management Inc /CT/ 1.30% of their portfolio | 605.3k $40.0m | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.19% of their portfolio | 582.1k $38.5m | Reduced -547.9k |
| Grantham, Mayo, Van Otterloo & Co. LLC 0.12% of their portfolio | 581.1k $38.4m | Reduced -4.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 570.2k $37.7m | Reduced -418.3k |
| MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio | 565.2k $37.4m | Added +144.9k |
| Russell Investments Group, Ltd. 0.05% of their portfolio | 521.3k $34.4m | Reduced -104.6k |
| Amundi 0.01% of their portfolio | 519.9k $34.2m | Reduced -179.8k |
| UBS Group AG 0.01% of their portfolio | 503.0k $33.3m | Added +52.2k |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 497.5k $32.9m | Reduced -395.2k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 485.9k $32.1m | Added +24.2k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 483.7k $32.0m | Reduced -49.5k |
| Swiss National Bank 0.02% of their portfolio | 483.3k $31.9m | Added +4.5k |
| Applied Finance Capital Management, LLC 1.33% of their portfolio | 471.7k $31.2m | Reduced -28.1k |
| CAPITAL FUND MANAGEMENT S.A. 0.28% of their portfolio | 382.3k $25.3m | Added +147.5k |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.21% of their portfolio | 369.9k $24.5m | Reduced -24.7k |
| TODD ASSET MANAGEMENT LLC 0.55% of their portfolio | 358.7k $23.7m | Reduced -22.1k |
| Schonfeld Strategic Advisors LLC 0.18% of their portfolio | 333.8k $22.1m | Reduced -290.7k |
| HRT FINANCIAL LP 0.12% of their portfolio | 328.1k $21.7m | Reduced -145.2k |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 318.9k $21.1m | Reduced -44.3k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 310.6k $20.5m | Reduced -60.6k |
| Bridgewater Associates, LP 0.12% of their portfolio | 308.6k $20.4m | Added +181.5k |
| Avidity Partners Management LP 1.04% of their portfolio | 308.1k $20.4m | Reduced -220.9k |
| Rafferty Asset Management, LLC 0.06% of their portfolio | 282.6k $18.7m | Reduced -20.5k |
| MACKENZIE FINANCIAL CORP 0.02% of their portfolio | 260.1k $17.2m | Reduced -121.6k |
| SECTOR GAMMA AS 5.19% of their portfolio | 259.0k $17.1m | Added +55.6k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 246.2k $16.3m | Reduced -68.6k |
| ASHFORD CAPITAL MANAGEMENT INC 1.99% of their portfolio | 240.6k $15.9m | Reduced -4.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 239.2k $15.8m | Added +62 |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.02% of their portfolio | 235.8k $15.6m | Reduced -11.4k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.03% of their portfolio | 225.4k $14.9m | Unchanged |
| Hudson Bay Capital Management LP 0.10% of their portfolio | 221.6k $14.6m | Added +2.3k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 220.8k $14.6m | Reduced -27.1k |
| ARK Investment Management LLC 0.13% of their portfolio | 211.5k $14.0m | Reduced -187.1k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.06% of their portfolio | 209.8k $13.9m | Reduced -160.6k |
| HighTower Advisors, LLC 0.02% of their portfolio | 209.7k $13.9m | Reduced -669 |
| Illinois Municipal Retirement Fund 0.19% of their portfolio | 202.1k $13.4m | Reduced -8.3k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 201.7k $13.2m | Reduced -50.2k |
| SEI INVESTMENTS CO 0.02% of their portfolio | 200.0k $13.2m | Added +17.5k |
| Andra AP-fonden 0.19% of their portfolio | 197.0k $13.0m | Reduced -50.8k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 194.7k $12.8m | Reduced -23.1k |
| Mitsubishi UFJ Trust & Banking Corp 0.03% of their portfolio | 192.4k $12.7m | Reduced -21.7k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 184.8k $12.2m | Reduced -15.7k |
| GRIMES & Co WEALTH MANAGEMENT, LLC 0.33% of their portfolio | 183.9k $12.2m | Reduced -8.4k |
| CANADA LIFE ASSURANCE Co 0.02% of their portfolio | 177.3k $11.7m | Reduced -5.3k |
| Engineers Gate Manager LP 0.23% of their portfolio | 175.5k $11.6m | New |
| ROYAL LONDON ASSET MANAGEMENT LTD 0.03% of their portfolio | 174.7k $11.5m | Reduced -8.2k |
| CHURCHILL MANAGEMENT Corp 0.13% of their portfolio | 174.1k $11.5m | Added +6.6k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 173.9k $11.5m | Reduced -38.1k |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 171.1k $11.3m | Reduced -11.6k |
| South Dakota Investment Council 0.22% of their portfolio | 170.7k $11.3m | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 168.4k $11.1m | Added +24.0k |
| SHIKIAR ASSET MANAGEMENT INC 2.90% of their portfolio | 167.2k $11.1m | Added +5.2k |