INCYTE CORP INCY
COM · Common Stock · CUSIP 45337C102 · ISIN US45337C1027
American pharmaceutical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, DE
- Founded2001
- Websiteincyte.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($72.6m this quarter). Holder counts are more reliable. Shares outstanding: 224.5m as of 2024-04-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $56.91. Options: 17 managers hold calls ($23.6m notional), 18 hold puts ($37.9m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 537 |
| Q4 2022 | 558 |
| Q1 2023 | 552 |
| Q2 2023 | 529 |
| Q3 2023 | 531 |
| Q4 2023 | 558 |
| Q1 2024 | 587 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 265 | 251 |
| Q1 2023 | 313 | 230 |
| Q2 2023 | 238 | 287 |
| Q3 2023 | 298 | 212 |
| Q4 2023 | 268 | 257 |
| Q1 2024 | 295 | 255 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $36.7m | $38.6m | 1.05 |
| Q3 2023 | $30.5m | $26.3m | 0.86 |
| Q4 2023 | $57.8m | $27.6m | 0.48 |
| Q1 2024 | $23.6m | $37.9m | 1.61 |
Biggest buyers
| MORGAN STANLEY | Added | +2.1m |
| ARMISTICE CAPITAL, LLC | Added | +2.0m |
| Sofinnova Investments, Inc. | Added | +1.0m |
| PRUDENTIAL FINANCIAL INC | Added | +642.8k |
| KBC Group NV | Added | +583.1k |
| Candriam S.C.A. | Added | +433.5k |
| Point72 Asset Management, L.P. | New | +380.1k |
| AQR CAPITAL MANAGEMENT LLC | Added | +378.0k |
| BANK OF AMERICA CORP /DE/ | Added | +352.9k |
| Schonfeld Strategic Advisors LLC | Added | +329.8k |
Biggest sellers
| BlackRock Inc. | Reduced | -1.1m |
| Pacer Advisors, Inc. | Reduced | -1.0m |
| TWO SIGMA INVESTMENTS, LP | Reduced | -857.3k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -761.8k |
| Dodge & Cox | Reduced | -674.4k |
| Pictet Asset Management Holding SA | Reduced | -626.3k |
| GOLDMAN SACHS GROUP INC | Reduced | -453.7k |
| WORLDQUANT MILLENNIUM ADVISORS LLC | Reduced | -434.4k |
| TWO SIGMA ADVISERS, LP | Reduced | -426.7k |
| Allspring Global Investments Holdings, LLC | Reduced | -358.3k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $4.0m70.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $3.5m62.2k shares |
| CITIGROUP INC | Added | $3.2m55.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.6m45.5k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $1.8m31.3k shares |
| BARCLAYS PLC | New | $1.7m30.0k shares |
| Walleye Capital LLC | Reduced | $1.2m20.5k shares |
| GROUP ONE TRADING LLC | Reduced | $1.0m18.1k shares |
| Walleye Trading LLC | Reduced | $979.9k17.2k shares |
| NOMURA HOLDINGS INC | New | $803.3k14.1k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $7.1m125.1k shares |
| JANE STREET GROUP, LLC | Added | $6.5m114.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $6.5m113.7k shares |
| SIMPLEX TRADING, LLC | Added | $4.2m72.9k shares |
| CITIGROUP INC | Added | $3.2m55.7k shares |
| IMC-Chicago, LLC | Added | $1.8m32.0k shares |
| BARCLAYS PLC | New | $1.7m30.0k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $1.2m21.1k shares |
| Walleye Capital LLC | Added | $1.2m20.4k shares |
| J. Goldman & Co LP | New | $1.2m20.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-0.1 pts · filed 2026-05-11
Stated purposeItem 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows: On May 8, 2026 the Adviser acquired beneficial ownership of 15,000 shares of common stock ("Common Stock") of Incyte Corporation (the "Issuer"), as a result of the exercise of 15,000 options to purchase Common Stock at $84.53 per share (the "Exercised Stock Options") held directly by Julian C. Baker. Julian C. Baker currently serves on the Issuer's board of directors (the "Board") as a representative of the Funds. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in the Exercised Stock Options. Julian C… Full filing |
15.6% |
| BlackRock, Inc. 13G · institution filed 2025-10-17 | 7.8% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 6.3% |
| DODGE & COX 13G · institution filed 2026-05-14 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 1 | $3.7m | — |
| Q3 2022 | 0 | — | 3 | $817.4k | — |
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Q1 2023 | 0 | — | 4 | $8.2m | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 2 | $1.9m | $1.4m |
| Q4 2023 | 0 | — | 1 | $78.6k | $78.6k |
| Q1 2024 | 0 | — | 2 | $525.2k | $525.2k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-01-03 | Stein Steven H EVP & Chief Medical Officer | Sold plan | $482.5k7.4k shares |
| 2024-01-02 | Iyengar Vijay K EVP, GMAPPS | Sold plan | $42.7k657 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 25.86% of their portfolio | 36.2m $2.1bn | Added +543 |
| BlackRock Inc. 0.03% of their portfolio | 23.2m $1.3bn | Reduced -1.1m |
| VANGUARD GROUP INC 0.03% of their portfolio | 22.7m $1.3bn | Added +196.4k |
| Dodge & Cox 0.51% of their portfolio | 15.4m $878.3m | Reduced -674.4k |
| STATE STREET CORP 0.03% of their portfolio | 9.9m $564.0m | Reduced -220.6k |
| MORGAN STANLEY 0.01% of their portfolio | 8.8m $499.5m | Added +2.1m |
| RENAISSANCE TECHNOLOGIES LLC 0.51% of their portfolio | 5.7m $323.4m | Added +122.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 4.4m $252.3m | Added +166.4k |
| Amundi 0.06% of their portfolio | 2.8m $149.0m | Reduced -231.0k |
| Invesco Ltd. 0.03% of their portfolio | 2.8m $160.6m | Added +82.0k |
| ACADIAN ASSET MANAGEMENT LLC 0.55% of their portfolio | 2.8m $158.4m | Reduced -234.5k |
| LSV ASSET MANAGEMENT 0.32% of their portfolio | 2.8m $156.9m | Added +63.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.64% of their portfolio | 2.5m $143.3m | Added +177.9k |
| ARMISTICE CAPITAL, LLC 3.32% of their portfolio | 2.2m $124.6m | Added +2.0m |
| Bellevue Group AG 1.87% of their portfolio | 2.2m $122.7m | Reduced -3.3k |
| Man Group plc 0.32% of their portfolio | 2.1m $119.6m | Reduced -277.8k |
| NORGES BANK 0.02% of their portfolio | 2.1m $116.9m | Added +89.1k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 1.9m $105.4m | Reduced -130.5k |
| Pictet Asset Management Holding SA 0.11% of their portfolio | 1.7m $97.5m | Reduced -626.3k |
| Legal & General Group Plc 0.03% of their portfolio | 1.7m $96.0m | Reduced -8.9k |
| FMR LLC 0.01% of their portfolio | 1.6m $92.5m | Added +293.8k |
| AQR CAPITAL MANAGEMENT LLC 0.15% of their portfolio | 1.6m $88.9m | Added +378.0k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.30% of their portfolio | 1.5m $87.8m | Reduced -29.8k |
| KBC Group NV 0.28% of their portfolio | 1.5m $87.7m | Added +583.1k |
| Candriam S.C.A. 0.54% of their portfolio | 1.5m $84.0m | Added +433.5k |
| D. E. Shaw & Co., Inc. 0.10% of their portfolio | 1.4m $78.9m | Reduced -115.4k |
| TWO SIGMA ADVISERS, LP 0.18% of their portfolio | 1.3m $76.5m | Reduced -426.7k |
| Sofinnova Investments, Inc. 4.46% of their portfolio | 1.3m $75.6m | Added +1.0m |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 1.3m $75.5m | Reduced -1.9k |
| Qube Research & Technologies Ltd 0.13% of their portfolio | 1.2m $69.7m | Added +264.5k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 1.2m $69.1m | Reduced -53.8k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio | 1.2m $68.7m | Reduced -11.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.29% of their portfolio | 1.2m $67.6m | Added +271.0k |
| HSBC HOLDINGS PLC 0.05% of their portfolio | 1.2m $66.9m | Added +156.9k |
| APG Asset Management N.V. 0.11% of their portfolio | 1.2m $61.4m | Added +95.5k |
| Robeco Institutional Asset Management B.V. 0.14% of their portfolio | 1.2m $65.6m | Added +85.9k |
| Woodline Partners LP 0.60% of their portfolio | 1.1m $64.6m | Added +675 |
| California Public Employees Retirement System 0.04% of their portfolio | 1.1m $63.2m | Reduced -60.7k |
| JUPITER ASSET MANAGEMENT LTD 0.59% of their portfolio | 1.1m $61.6m | Reduced -11.6k |
| TWO SIGMA INVESTMENTS, LP 0.15% of their portfolio | 1.1m $60.1m | Reduced -857.3k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.22% of their portfolio | 1.0m $59.7m | Reduced -212.8k |
| DEUTSCHE BANK AG\ 0.03% of their portfolio | 1.0m $59.5m | Reduced -64.3k |
| Russell Investments Group, Ltd. 0.09% of their portfolio | 1.0m $58.9m | Added +70.5k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 950.6k $54.2m | Reduced -22 |
| FEDERATED HERMES, INC. 0.12% of their portfolio | 935.4k $53.3m | Added +44.3k |
| FIRST TRUST ADVISORS LP 0.05% of their portfolio | 894.0k $50.9m | Reduced -24.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 881.1k $50.2m | Reduced -161.8k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 856.5k $48.8m | Reduced -34.7k |
| MILLENNIUM MANAGEMENT LLC 0.04% of their portfolio | 835.0k $47.6m | Reduced -761.8k |
| PRUDENTIAL FINANCIAL INC 0.06% of their portfolio | 770.4k $43.9m | Added +642.8k |
| CREDIT SUISSE AG/ 0.04% of their portfolio | 742.2k $42.3m | Added +585 |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 724.8k $41.3m | Reduced -453.7k |
| Swedbank AB 0.05% of their portfolio | 657.2k $37.4m | Added +24.3k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 652.8k $37.2m | Added +205.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 643.7k $36.7m | Reduced -246.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 638.6k $36.4m | Added +352.9k |
| Schonfeld Strategic Advisors LLC 0.28% of their portfolio | 629.8k $35.9m | Added +329.8k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 625.5k $35.6m | Reduced -38.4k |
| Assenagon Asset Management S.A. 0.09% of their portfolio | 578.4k $33.0m | Reduced -56.2k |
| Swiss National Bank 0.02% of their portfolio | 570.5k $32.5m | Reduced -25.1k |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.39% of their portfolio | 560.1k $31.9m | Reduced -434.4k |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 546.0k $31.1m | Reduced -137.0k |
| Grantham, Mayo, Van Otterloo & Co. LLC 0.11% of their portfolio | 524.8k $29.9m | Reduced -15.3k |
| PANAGORA ASSET MANAGEMENT INC 0.15% of their portfolio | 501.9k $28.6m | Added +17.5k |
| BARCLAYS PLC 0.01% of their portfolio | 493.3k $28.1m | Added +5.5k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 490.3k $27.9m | Added +122 |
| Squarepoint Ops LLC 0.11% of their portfolio | 463.9k $26.4m | Reduced -185.6k |
| ARK Investment Management LLC 0.17% of their portfolio | 438.7k $25.0m | Reduced -92.9k |
| CITIGROUP INC 0.03% of their portfolio | 426.3k $24.3m | Reduced -62.3k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.03% of their portfolio | 420.4k $23.9m | Reduced -42.3k |
| Cubist Systematic Strategies, LLC 0.27% of their portfolio | 419.2k $23.9m | Added +132.3k |
| UBS Group AG 0.01% of their portfolio | 404.1k $23.0m | Reduced -118.0k |
| Allspring Global Investments Holdings, LLC 0.04% of their portfolio | 402.0k $22.9m | Reduced -358.3k |
| Capital World Investors 0.00% of their portfolio | 396.0k $22.6m | Unchanged |
| MACKENZIE FINANCIAL CORP 0.03% of their portfolio | 393.8k $22.4m | Added +20.0k |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 386.4k $22.0m | Reduced -217.4k |
| Point72 Asset Management, L.P. 0.06% of their portfolio | 380.1k $21.7m | New |
| Bridgewater Associates, LP 0.11% of their portfolio | 366.6k $20.9m | Reduced -1.4k |
| ASHFORD CAPITAL MANAGEMENT INC 2.69% of their portfolio | 348.8k $19.9m | Reduced -23.9k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.06% of their portfolio | 323.3k $18.4m | Reduced -12.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 305.5k $17.4m | Added +2.6k |
| Hudson Bay Capital Management LP 0.15% of their portfolio | 300.4k $17.1m | Reduced -27.1k |
| Applied Finance Capital Management, LLC 1.20% of their portfolio | 298.4k $17.0m | New |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 297.2k $16.9m | Reduced -34.3k |
| Mitsubishi UFJ Trust & Banking Corp 0.04% of their portfolio | 294.5k $16.7m | Reduced -4.5k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 292.8k $16.7m | Reduced -13.6k |
| MARSHALL WACE, LLP 0.03% of their portfolio | 291.7k $16.6m | Added +249.0k |
| DANSKE BANK A/S 0.05% of their portfolio | 280.3k $16.0m | First filing |
| Trexquant Investment LP 0.31% of their portfolio | 272.2k $15.5m | Reduced -23.2k |
| SECTOR GAMMA AS 4.25% of their portfolio | 264.9k $15.1m | Reduced -133.8k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 258.6k $14.7m | Added +204.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 253.4k $14.4m | Reduced -286 |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 245.7k $14.0m | Reduced -15.9k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.04% of their portfolio | 239.1k $17.3m | Added +14.2k |
| Korea Investment CORP 0.03% of their portfolio | 238.1k $13.6m | Added +1.3k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.02% of their portfolio | 234.6k $13.4m | Reduced -133.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio | 228.2k $13.0m | Reduced -76.0k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.02% of their portfolio | 224.1k $12.8m | Added +48.4k |
| Gotham Asset Management, LLC 0.19% of their portfolio | 219.5k $12.5m | Added +61.0k |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 219.2k $12.5m | Reduced -169.0k |