INCYTE CORP INCY
COM · Common Stock · CUSIP 45337C102 · ISIN US45337C1027
American pharmaceutical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, DE
- Founded2001
- Websiteincyte.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($32.5m this quarter). Holder counts are more reliable. Shares outstanding: 224.1m as of 2023-07-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $62.24. Options: 15 managers hold calls ($36.7m notional), 16 hold puts ($38.6m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 537 |
| Q4 2022 | 558 |
| Q1 2023 | 552 |
| Q2 2023 | 529 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 265 | 251 |
| Q1 2023 | 313 | 230 |
| Q2 2023 | 238 | 287 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $43.1m | $48.3m | 1.12 |
| Q4 2022 | $78.5m | $70.9m | 0.90 |
| Q1 2023 | $45.5m | $24.5m | 0.54 |
| Q2 2023 | $36.7m | $38.6m | 1.05 |
Biggest buyers
| BlackRock Inc. | Added | +3.2m |
| CITADEL ADVISORS LLC | Added | +1.8m |
| TWO SIGMA INVESTMENTS, LP | Added | +1.5m |
| Man Group plc | New | +1.4m |
| D. E. Shaw & Co., Inc. | Added | +931.6k |
| TWO SIGMA ADVISERS, LP | Added | +897.9k |
| MILLENNIUM MANAGEMENT LLC | Added | +760.8k |
| STATE STREET CORP | Added | +527.4k |
| Squarepoint Ops LLC | Added | +505.1k |
| Balyasny Asset Management L.P. | New | +384.7k |
Biggest sellers
| ROYAL BANK OF CANADA | Reduced | -12.1m |
| FIRST TRUST ADVISORS LP | Reduced | -2.5m |
| FMR LLC | Reduced | -1.3m |
| Man Group plc | Sold out | -820.2k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -774.2k |
| Pacer Advisors, Inc. | Reduced | -743.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -622.6k |
| Allianz Asset Management GmbH | Reduced | -592.5k |
| AVIVA PLC | Reduced | -503.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Reduced | -480.4k |
Biggest calls
| GOLDMAN SACHS GROUP INC | Added | $8.0m128.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $7.7m123.7k shares |
| CITADEL ADVISORS LLC | Added | $6.0m96.3k shares |
| JANE STREET GROUP, LLC | Added | $4.8m77.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.8m44.7k shares |
| Walleye Trading LLC | Added | $2.7m43.2k shares |
| PEAK6 Investments LLC | Reduced | $1.6m25.1k shares |
| MILLENNIUM MANAGEMENT LLC | New | $1.2m20.0k shares |
| IMC-Chicago, LLC | Added | $747.0k12.0k shares |
| Paloma Partners Management Co | New | $647.4k10.4k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $8.3m134.0k shares |
| GOLDMAN SACHS GROUP INC | Added | $8.0m128.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $6.2m99.4k shares |
| PEAK6 Investments LLC | Reduced | $4.3m69.4k shares |
| SIMPLEX TRADING, LLC | Added | $3.3m52.8k shares |
| JANE STREET GROUP, LLC | Added | $2.6m41.3k shares |
| GROUP ONE TRADING LLC | Added | $1.9m31.0k shares |
| CAPSTONE INVESTMENT ADVISORS, LLC | Reduced | $1.2m18.5k shares |
| IMC-Chicago, LLC | Added | $1.0m16.5k shares |
| J. Goldman & Co LP | New | $840.4k13.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-0.1 pts · filed 2026-05-11
Stated purposeItem 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows: On May 8, 2026 the Adviser acquired beneficial ownership of 15,000 shares of common stock ("Common Stock") of Incyte Corporation (the "Issuer"), as a result of the exercise of 15,000 options to purchase Common Stock at $84.53 per share (the "Exercised Stock Options") held directly by Julian C. Baker. Julian C. Baker currently serves on the Issuer's board of directors (the "Board") as a representative of the Funds. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in the Exercised Stock Options. Julian C… Full filing |
15.6% |
| BlackRock, Inc. 13G · institution filed 2025-10-17 | 7.8% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 6.3% |
| DODGE & COX 13G · institution filed 2026-05-14 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 1 | $115.6m | 2 | $467.7k | — |
| Q1 2022 | 1 | $170.8m | 3 | $2.6m | — |
| Q2 2022 | 0 | — | 1 | $3.7m | — |
| Q3 2022 | 0 | — | 3 | $817.4k | — |
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Q1 2023 | 0 | — | 4 | $8.2m | — |
| Q2 2023 | 0 | — | 0 | — | — |
None reported in Q2 2023.
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 13.03% of their portfolio | 36.2m $2.3bn | Added +2.7k |
| BlackRock Inc. 0.04% of their portfolio | 23.9m $1.5bn | Added +3.2m |
| VANGUARD GROUP INC 0.03% of their portfolio | 21.9m $1.4bn | Added +110.9k |
| Dodge & Cox 0.80% of their portfolio | 19.3m $1.2bn | Reduced -54.4k |
| STATE STREET CORP 0.03% of their portfolio | 9.9m $613.2m | Added +527.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.43% of their portfolio | 4.8m $300.6m | Reduced -774.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.03% of their portfolio | 4.1m $253.2m | Added +115.7k |
| Invesco Ltd. 0.06% of their portfolio | 3.8m $236.6m | Reduced -262.5k |
| GOLDMAN SACHS GROUP INC 0.04% of their portfolio | 2.7m $167.4m | Added +264.5k |
| Bellevue Group AG 2.34% of their portfolio | 2.6m $164.4m | Reduced -199.7k |
| PICTET ASSET MANAGEMENT SA 0.16% of their portfolio | 2.1m $131.4m | Reduced -106.1k |
| TWO SIGMA INVESTMENTS, LP 0.35% of their portfolio | 2.1m $131.0m | Added +1.5m |
| TWO SIGMA ADVISERS, LP 0.33% of their portfolio | 2.1m $130.3m | Added +897.9k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 2.0m $125.0m | Reduced -73.5k |
| MORGAN STANLEY 0.01% of their portfolio | 1.9m $120.3m | Added +33.4k |
| NORGES BANK 0.02% of their portfolio | 1.9m $115.7m | Added +44.5k |
| CITADEL ADVISORS LLC 0.13% of their portfolio | 1.8m $113.8m | Added +1.8m |
| D. E. Shaw & Co., Inc. 0.18% of their portfolio | 1.8m $112.4m | Added +931.6k |
| Legal & General Group Plc 0.04% of their portfolio | 1.8m $111.4m | Added +238.0k |
| ARMISTICE CAPITAL, LLC 2.78% of their portfolio | 1.8m $110.6m | Reduced -96.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.64% of their portfolio | 1.8m $110.3m | Added +103.5k |
| ACADIAN ASSET MANAGEMENT LLC 0.44% of their portfolio | 1.7m $106.7m | Added +290.2k |
| Man Group plc 0.27% of their portfolio | 1.4m $86.6m | New |
| MILLENNIUM MANAGEMENT LLC 0.09% of their portfolio | 1.4m $86.2m | Added +760.8k |
| Paradigm Biocapital Advisors LP 6.96% of their portfolio | 1.4m $86.0m | Added +120.0k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 1.4m $86.0m | Reduced -14.5k |
| Amundi 0.04% of their portfolio | 1.4m $85.7m | Reduced -304.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.2m $74.4m | Reduced -622.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 1.2m $74.3m | Added +37.3k |
| LSV ASSET MANAGEMENT 0.16% of their portfolio | 1.2m $73.4m | Reduced -13.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% of their portfolio | 1.2m $84.7m | Unchanged |
| California Public Employees Retirement System 0.06% of their portfolio | 1.2m $72.4m | Reduced -13.5k |
| FMR LLC 0.01% of their portfolio | 1.1m $70.1m | Reduced -1.3m |
| HSBC HOLDINGS PLC 0.07% of their portfolio | 1.1m $69.4m | Added +122.7k |
| Polar Capital Holdings Plc 0.47% of their portfolio | 1.1m $67.9m | Reduced -10.0k |
| Candriam S.C.A. 0.45% of their portfolio | 993.2k $61.8m | Added +156.0k |
| DEUTSCHE BANK AG\ 0.03% of their portfolio | 990.1k $61.6m | Added +101.6k |
| AQR CAPITAL MANAGEMENT LLC 0.12% of their portfolio | 941.8k $58.4m | Added +95.3k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 845.5k $52.6m | Added +92.9k |
| APG Asset Management N.V. 0.10% of their portfolio | 836.8k $47.7m | Reduced -87.4k |
| FIRST TRUST ADVISORS LP 0.05% of their portfolio | 746.8k $46.5m | Reduced -2.5m |
| Squarepoint Ops LLC 0.25% of their portfolio | 736.5k $45.8m | Added +505.1k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.02% of their portfolio | 711.2k $44.3m | Reduced -425.9k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 700.9k $43.6m | Added +92.0k |
| JUPITER ASSET MANAGEMENT LTD 0.47% of their portfolio | 698.2k $43.4m | Added +231.0k |
| Swiss National Bank 0.03% of their portfolio | 684.4k $42.6m | Reduced -66.1k |
| CREDIT SUISSE AG/ 0.04% of their portfolio | 678.4k $42.2m | Reduced -335.3k |
| Hudson Bay Capital Management LP 0.42% of their portfolio | 670.0k $41.7m | Added +349.6k |
| Robeco Institutional Asset Management B.V. 0.11% of their portfolio | 663.1k $41.3m | Added +86.1k |
| Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio | 657.3k $40.9m | Reduced -93.5k |
| Qube Research & Technologies Ltd 0.16% of their portfolio | 644.8k $40.1m | Added +13.1k |
| Russell Investments Group, Ltd. 0.07% of their portfolio | 569.3k $35.4m | Reduced -114.1k |
| Swedbank AB 0.06% of their portfolio | 564.1k $35.1m | Unchanged |
| RHUMBLINE ADVISERS 0.04% of their portfolio | 554.4k $34.5m | Added +2.9k |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 532.6k $33.2m | Reduced -12.1m |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 521.1k $32.4m | Reduced -367.9k |
| Connor, Clark & Lunn Investment Management Ltd. 0.16% of their portfolio | 513.7k $32.0m | Added +372.3k |
| Woodline Partners LP 0.37% of their portfolio | 500.0k $31.1m | Reduced -92.8k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.05% of their portfolio | 495.0k $30.8m | Added +28.7k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 494.5k $30.8m | Reduced -1.1k |
| UBS Group AG 0.01% of their portfolio | 487.1k $30.3m | Added +271.0k |
| ARK Investment Management LLC 0.19% of their portfolio | 467.6k $29.1m | Reduced -260.4k |
| Cubist Systematic Strategies, LLC 0.32% of their portfolio | 459.8k $28.6m | Added +337.7k |
| ASHFORD CAPITAL MANAGEMENT INC 3.99% of their portfolio | 458.8k $28.6m | Added +3.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 442.8k $27.6m | Added +129.0k |
| Skandinaviska Enskilda Banken AB (publ) 0.18% of their portfolio | 438.4k $27.3m | Added +23.7k |
| Grantham, Mayo, Van Otterloo & Co. LLC 0.12% of their portfolio | 420.6k $26.2m | Reduced -7.9k |
| BARCLAYS PLC 0.02% of their portfolio | 410.8k $25.6m | Reduced -54.5k |
| SECTOR GAMMA AS 5.54% of their portfolio | 397.5k $24.7m | Reduced -34.7k |
| Capital World Investors 0.00% of their portfolio | 396.0k $24.7m | Unchanged |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 390.8k $24.7m | Reduced -211.1k |
| Balyasny Asset Management L.P. 0.07% of their portfolio | 384.7k $23.9m | New |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.40% of their portfolio | 378.9k $23.6m | Added +175.8k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.11% of their portfolio | 375.8k $23.4m | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 363.6k $22.6m | Reduced -331.5k |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 6.79% of their portfolio | 358.5k $22.3m | Added +79.5k |
| FEDERATED HERMES, INC. 0.05% of their portfolio | 352.6k $22.0m | Added +312.7k |
| PANAGORA ASSET MANAGEMENT INC 0.13% of their portfolio | 343.3k $21.4m | Reduced -13.5k |
| CITIGROUP INC 0.03% of their portfolio | 340.4k $21.2m | Reduced -159.6k |
| Bridgewater Associates, LP 0.12% of their portfolio | 317.7k $19.8m | Added +41.2k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 314.3k $19.6m | Added +73.6k |
| MACKENZIE FINANCIAL CORP 0.03% of their portfolio | 296.5k $18.4m | Added +53.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio | 295.5k $18.4m | Reduced -21.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.04% of their portfolio | 289.0k $18.0m | Added +34.7k |
| Baird Financial Group, Inc. 0.04% of their portfolio | 268.9k $16.7m | Added +52.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 260.8k $16.2m | Reduced -7.8k |
| Schonfeld Strategic Advisors LLC 0.13% of their portfolio | 249.2k $15.5m | New |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.03% of their portfolio | 233.6k $14.5m | Reduced -5.6k |
| INTECH INVESTMENT MANAGEMENT LLC 0.15% of their portfolio | 231.1k $14.4m | Reduced -13.3k |
| Mitsubishi UFJ Trust & Banking Corp 0.03% of their portfolio | 227.6k $14.2m | Reduced -3.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 227.3k $14.1m | Added +51.9k |
| Summit Global Investments 0.94% of their portfolio | 227.1k $14.1m | Reduced -16.0k |
| CANADA LIFE ASSURANCE Co 0.03% of their portfolio | 226.8k $14.2m | Added +32.8k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.02% of their portfolio | 224.1k $14.0m | Reduced -151.4k |
| Illinois Municipal Retirement Fund 0.27% of their portfolio | 214.9k $13.4m | Added +19.7k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio | 208.2k $13.0m | Reduced -13.9k |
| VOYA INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 202.8k $12.6m | Added +16.3k |
| TORONTO DOMINION BANK 0.01% of their portfolio | 199.2k $12.4m | Added +103.1k |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 197.8k $12.3m | Reduced -358.1k |
| South Dakota Investment Council 0.25% of their portfolio | 189.9k $11.8m | Reduced -12.0k |