IMMUNOCORE HLDGS PLC IMCR
ADS · ADR · CUSIP 45258D105 · ISIN US45258D1054
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersPhiladelphia, United Kingdom
- Founded2008
- Websiteimmunocore.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $34.69. Options: 5 managers hold calls ($4.6m notional), 6 hold puts ($3.2m).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 86 |
| Q4 2022 | 105 |
| Q1 2023 | 111 |
| Q2 2023 | 122 |
| Q3 2023 | 127 |
| Q4 2023 | 135 |
| Q1 2024 | 151 |
| Q2 2024 | 140 |
| Q3 2024 | 131 |
| Q4 2024 | 117 |
| Q1 2025 | 118 |
| Q2 2025 | 135 |
| Q3 2025 | 133 |
| Q4 2025 | 149 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 93 | 52 |
| Q2 2024 | 82 | 71 |
| Q3 2024 | 65 | 65 |
| Q4 2024 | 47 | 71 |
| Q1 2025 | 58 | 45 |
| Q2 2025 | 75 | 54 |
| Q3 2025 | 58 | 65 |
| Q4 2025 | 73 | 49 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $6.5m | $3.5m | 0.53 |
| Q2 2025 | $9.2m | $36.6m | 3.98 |
| Q3 2025 | $11.7m | $63.0m | 5.39 |
| Q4 2025 | $4.6m | $3.2m | 0.71 |
Biggest buyers
| Vestal Point Capital, LP | New | +585.0k |
| JANUS HENDERSON GROUP PLC | New | +454.4k |
| TANG CAPITAL MANAGEMENT LLC | Added | +322.9k |
| ARMISTICE CAPITAL, LLC | Added | +274.0k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +262.3k |
| Fiera Capital Corp | Added | +249.7k |
| PRINCIPAL FINANCIAL GROUP INC | Added | +247.0k |
| PRIMECAP MANAGEMENT CO/CA/ | Added | +207.3k |
| Deep Track Capital, LP | Added | +204.0k |
| CITADEL ADVISORS LLC | Added | +192.1k |
Biggest sellers
| GROUPAMA ASSET MANAGMENT | Sold out | -600.0k |
| Caption Management, LLC | Reduced | -369.3k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -354.4k |
| T. Rowe Price Investment Management, Inc. | Reduced | -229.0k |
| CITIGROUP INC | Reduced | -218.4k |
| Kynam Capital Management, LP | Reduced | -152.8k |
| Trexquant Investment LP | Sold out | -100.6k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -87.2k |
| BVF INC/IL | Reduced | -85.3k |
| MARSHALL WACE, LLP | Reduced | -62.1k |
Biggest calls
| CANTOR FITZGERALD, L. P. | Reduced | $1.8m50.5k shares |
| CITIGROUP INC | Reduced | $867.8k25.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $867.8k25.0k shares |
| JANE STREET GROUP, LLC | New | $753.2k21.7k shares |
| SIMPLEX TRADING, LLC | Added | $326.3k9.4k shares |
Biggest puts
| CITIGROUP INC | Reduced | $867.8k25.0k shares |
| Caption Management, LLC | Reduced | $867.8k25.0k shares |
| TUDOR INVESTMENT CORP ET AL | New | $763.6k22.0k shares |
| WOLVERINE ASSET MANAGEMENT LLC | Reduced | $444.3k12.8k shares |
| CITADEL ADVISORS LLC | Added | $274.2k7.9k shares |
| SIMPLEX TRADING, LLC | New | $6.9k200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.4 pts · filed 2026-08-13 | 11.6% |
| Jallal Bahija 13G · exempt (held before listing) new · filed 2025-02-14 | 8.2% |
| PRIMECAP MANAGEMENT CO/CA/ 13G · institution +2.2 pts · filed 2025-08-14 | 7.5% |
| Bellevue Group AG 13G · institution new · filed 2025-11-14 | 5.6% |
| TANG CAPITAL MANAGEMENT LLC 13G · passive investor new · filed 2025-10-24 | 5.2% |
Fell to 5% or below in the last year: FMR LLC (3.6%, 2026-10-07), Vestal Point Capital, LP (3.5%, 2026-08-14), T. Rowe Price Investment Management, Inc. (3.7%, 2026-05-15)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 2 | $8.7m | $8.7m |
| Q2 2024 | 0 | — | 1 | $280.3k | $280.3k |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 1 | $24.0m | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 1 | $4.8m | $4.8m |
| Q4 2025 | 0 | — | 1 | $5.0m | $5.0m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-05 | Berman David M HEAD OF R&D | Sold plan | $23.0k572 shares |
| 2025-12-04 | Berman David M HEAD OF R&D | Sold plan | $1.3m31.3k shares |
| 2025-11-28 | Berman David M HEAD OF R&D | Sold plan | $221.3k5.5k shares |
| 2025-11-26 | Berman David M HEAD OF R&D | Sold plan | $2.8m69.4k shares |
| 2025-11-25 | Berman David M HEAD OF R&D | Sold plan | $721.3k18.0k shares |
| 2025-11-24 | Berman David M HEAD OF R&D | Sold plan | $4.0k100 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| T. Rowe Price Investment Management, Inc. 0.09% of their portfolio | 6.8m $237.2m | Reduced -229.0k |
| RTW INVESTMENTS, LP 1.69% of their portfolio | 4.9m $169.0m | Unchanged |
| WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio | 4.7m $162.9m | Reduced -87.2k |
| FMR LLC 0.01% of their portfolio | 4.5m $157.6m | Added +118.8k |
| PRIMECAP MANAGEMENT CO/CA/ 0.10% of their portfolio | 4.0m $137.5m | Added +207.3k |
| Bellevue Group AG 1.84% of their portfolio | 2.8m $97.1m | Unchanged |
| TANG CAPITAL MANAGEMENT LLC 4.51% of their portfolio | 2.6m $91.2m | Added +322.9k |
| BAKER BROS. ADVISORS LP 0.47% of their portfolio | 2.3m $80.6m | Unchanged |
| Deep Track Capital, LP 1.59% of their portfolio | 2.0m $69.6m | Added +204.0k |
| BVF INC/IL 1.69% of their portfolio | 1.5m $50.3m | Reduced -85.3k |
| ARMISTICE CAPITAL, LLC 0.93% of their portfolio | 1.1m $38.1m | Added +274.0k |
| Fiera Capital Corp 0.12% of their portfolio | 1.0m $36.3m | Added +249.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 968.8k $33.6m | Reduced -48.0k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 911.6k $31.6m | Reduced -354.4k |
| Kynam Capital Management, LP 1.94% of their portfolio | 856.5k $29.7m | Reduced -152.8k |
| Logos Global Management LP 1.97% of their portfolio | 850.0k $29.5m | Unchanged |
| Trails Edge Capital Partners, LP 5.85% of their portfolio | 682.6k $23.7m | First filing |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 658.4k $22.9m | Added +247.0k |
| Vestal Point Capital, LP 0.74% of their portfolio | 585.0k $20.3m | New |
| Point72 Asset Management, L.P. 0.03% of their portfolio | 504.2k $17.5m | Reduced -31.7k |
| ACADIAN ASSET MANAGEMENT LLC 0.03% of their portfolio | 461.8k $16.0m | Added +262.3k |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 454.4k $15.7m | New |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 407.4k $14.1m | Reduced -35.0k |
| Frazier Life Sciences Management, L.P. 0.36% of their portfolio | 384.8k $13.4m | Unchanged |
| Hudson Bay Capital Management LP 0.08% of their portfolio | 383.6k $13.3m | Added +50.0k |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 359.3k $12.5m | Added +138.6k |
| BlackRock, Inc. 0.00% of their portfolio | 329.1k $11.4m | Added +83.9k |
| TWO SIGMA ADVISERS, LP 0.02% of their portfolio | 322.3k $11.2m | Reduced -7.7k |
| Woodline Partners LP 0.04% of their portfolio | 316.7k $11.0m | Added +109.2k |
| TD Asset Management Inc 0.01% of their portfolio | 292.8k $10.2m | Added +3.9k |
| MORGAN STANLEY 0.00% of their portfolio | 287.1k $10.0m | Added +17.9k |
| Candriam S.C.A. 0.05% of their portfolio | 269.7k $9.4m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 234.7k $8.1m | Added +22.9k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 234.3k $8.1m | Added +192.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 211.1k $7.3m | Unchanged |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 183.9k $6.4m | New |
| Rhenman & Partners Asset Management AB 0.50% of their portfolio | 153.3k $5.3m | Added +125.0k |
| Legal & General Group Plc 0.00% of their portfolio | 149.3k $5.2m | Added +23.6k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 140.9k $4.9m | Reduced -1.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 135.2k $4.7m | New |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 109.8k $3.8m | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 103.3k $3.6m | Reduced -3.8k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 100.9k $3.5m | Added +60.7k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 95.9k $3.3m | New |
| Caption Management, LLC 0.14% of their portfolio | 94.4k $3.3m | Reduced -369.3k |
| STATE STREET CORP 0.00% of their portfolio | 93.6k $3.2m | Added +2.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 85.2k $2.9m | Added +6.3k |
| Eschler Asset Management LLP 1.89% of their portfolio | 80.0k $2.8m | Added +40.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 77.2k $2.7m | Reduced -6.5k |
| Exome Asset Management LLC 1.32% of their portfolio | 76.8k $2.7m | New |
| DIADEMA PARTNERS LP 1.45% of their portfolio | 70.3k $2.4m | Reduced -54.1k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 61.2k $2.1m | Reduced -62.1k |
| Jump Financial, LLC 0.03% of their portfolio | 61.1k $2.1m | Reduced -9.9k |
| Elmind Capital, LP 0.60% of their portfolio | 58.2k $2.0m | First filing |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 55.2k $1.9m | Reduced -5.2k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 50.3k $1.7m | Added +15.4k |
| Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio | 48.6k $1.7m | Reduced -14.1k |
| Y-Intercept (Hong Kong) Ltd 0.04% of their portfolio | 48.2k $1.7m | Added +2.9k |
| Eagle Health Investments LP 0.35% of their portfolio | 46.3k $1.6m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 43.0k $1.5m | Reduced -2.9k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 42.5k $1.5m | Reduced -3.2k |
| HUSSMAN STRATEGIC ADVISORS, INC. 0.35% of their portfolio | 42.0k $1.5m | New |
| ALPS ADVISORS INC 0.01% of their portfolio | 41.5k $1.4m | Added +17.1k |
| Quadrature Capital Ltd 0.01% of their portfolio | 38.6k $1.3m | Added +19.6k |
| Crossmark Global Holdings, Inc. 0.02% of their portfolio | 36.4k $1.3m | Added +58 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 35.2k $1.2m | Added +25.0k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 33.6k $1.2m | New |
| HighVista Strategies LLC 0.29% of their portfolio | 33.0k $1.1m | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 32.6k $1.1m | Added +23.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 32.4k $1.1m | Reduced -26.6k |
| ASSETMARK, INC 0.00% of their portfolio | 31.7k $1.1m | Reduced -2.4k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.00% of their portfolio | 28.2k $977.6k | New |
| Persistent Asset Partners Ltd 0.47% of their portfolio | 27.9k $969.5k | Reduced -683 |
| State of New Jersey Common Pension Fund D 0.00% of their portfolio | 27.7k $960.2k | Added +1.8k |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 27.6k $959.7k | Added +7.7k |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 27.6k $958.2k | Added +17.1k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 25.2k $873.4k | Unchanged |
| Aquatic Capital Management LLC 0.02% of their portfolio | 25.0k $866.9k | New |
| NEOS Investment Management LLC 0.00% of their portfolio | 22.6k $784.4k | Added +1.2k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 22.2k $771.6k | Added +1.1k |
| Orion Porfolio Solutions, LLC 0.01% of their portfolio | 22.0k $763.6k | Reduced -1.3k |
| XTX Topco Ltd 0.02% of their portfolio | 22.0k $763.3k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 20.2k $700.5k | Added +445 |
| Virtus Investment Advisers, LLC 0.18% of their portfolio | 18.6k $644.5k | Added +6.1k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.04% of their portfolio | 16.5k $573.0k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 15.4k $534.1k | New |
| China Universal Asset Management Co., Ltd. 0.04% of their portfolio | 15.1k $524.4k | Added +8.1k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 15.0k $1.0m | Unchanged |
| PSP Research LLC 0.44% of their portfolio | 14.4k $500.7k | First filing |
| DNB Asset Management AS 0.00% of their portfolio | 13.1k $453.5k | Added +5.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 11.7k $404.8k | Reduced -2.3k |
| Bridgewater Associates, LP 0.00% of their portfolio | 10.0k $345.4k | New |
| Graham Capital Management, L.P. 0.01% of their portfolio | 9.7k $336.8k | Reduced -3.4k |
| R Squared Ltd 0.14% of their portfolio | 8.8k $307.1k | Added +606 |
| SG Americas Securities, LLC 0.00% of their portfolio | 8.7k $301.0k | Added +1.1k |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.00% of their portfolio | 8.2k $283.9k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 7.2k $250.5k | Reduced -34.0k |
| Snowden Capital Advisors LLC 0.01% of their portfolio | 7.0k $241.9k | Reduced -578 |
| CITIGROUP INC 0.00% of their portfolio | 6.9k $239.5k | Reduced -218.4k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 6.8k $237.4k | Unchanged |