HERON THERAPEUTICS INC HRTX
COM · Common Stock · CUSIP 427746102
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.9k this quarter). Holder counts are more reliable. Shares outstanding: 118.9m as of 2022-11-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.50. Options: 6 managers hold calls ($2.6m notional), 3 hold puts ($124.2k).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 185 |
| Q4 2022 | 176 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $593.0k | $487.0k | 0.82 |
| Q4 2022 | $2.6m | $124.2k | 0.05 |
Biggest buyers
| Rubric Capital Management LP | Added | +9.2m |
| Velan Capital Investment Management LP | New | +2.5m |
| MILLENNIUM MANAGEMENT LLC | Added | +1.8m |
| Clearline Capital LP | New | +1.0m |
| GREAT POINT PARTNERS LLC | Added | +715.0k |
| PANAGORA ASSET MANAGEMENT INC | Added | +455.9k |
| CITADEL ADVISORS LLC | Added | +441.2k |
| Qube Research & Technologies Ltd | Added | +399.2k |
| PALISADE CAPITAL MANAGEMENT, LP | Added | +397.3k |
| BlackRock Inc. | Added | +392.4k |
Biggest sellers
| STATE STREET CORP | Reduced | -6.3m |
| TANG CAPITAL MANAGEMENT LLC | Reduced | -3.1m |
| MONTANOVA CAPITAL, LLC | Sold out | -2.8m |
| Deep Track Capital, LP | Reduced | -2.1m |
| ArrowMark Colorado Holdings LLC | Reduced | -2.0m |
| GOLDMAN SACHS GROUP INC | Reduced | -1.1m |
| ORBIMED ADVISORS LLC | Sold out | -1.1m |
| VANGUARD GROUP INC | Reduced | -946.6k |
| Graham Capital Management, L.P. | Sold out | -890.6k |
| Integral Health Asset Management, LLC | Sold out | -700.0k |
Biggest calls
| Point72 Asset Management, L.P. | New | $2.5m1.0m shares |
| CITADEL ADVISORS LLC | Reduced | $48.0k19.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $45.8k18.3k shares |
| SIMPLEX TRADING, LLC | Added | $14.0k5.9k shares |
| GROUP ONE TRADING LLC | Reduced | $5.8k2.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $96.8k38.7k shares |
| CITADEL ADVISORS LLC | Reduced | $27.5k11.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Rubric Capital Management LP
13D · may seek influence
-1.6 pts · filed 2025-10-17
Stated purposeOn October 15, 2025, the Issuer filed a Current Report on Form 8-K with the SEC disclosing that it obtained Stockholder Approval, as a result of which, the 94,610 shares of Preferred Stock beneficially owned by the Reporting Persons automatically converted, without any action on the part of the holders thereof, into 946,100 Shares. Additionally, as previously disclosed, on August 8, 2025, a certain Rubric Fund entered into the Note Purchase Agreement with the Issuer, pursuant to which the Issuer issued and sold to such Rubric Fund $35,000,000 aggregate principal amount of Notes for an aggregate purchase price of $33,250,000. The Convertible Note Issuance provided for the issuance of Notes with (i) a maturity date of March 1, 2031, (ii) a 5% original issuance discount, (iii) 5% per annum i… Full filing |
15.9% |
| Clearline Capital LP 13G · institution +1.4 pts · filed 2026-02-17 | 6.7% |
Fell to 5% or below in the last year: Adage Capital Management, L.P. (0.0%, 2026-05-13), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 2 | $5.4k | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 1 | $7.2k | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
None reported in Q4 2022.
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 11.9m $29.7m | Reduced -15.4k |
| Rubric Capital Management LP 1.29% of their portfolio | 11.8m $29.4m | Added +9.2m |
| BlackRock Inc. 0.00% of their portfolio | 9.7m $24.1m | Added +392.4k |
| BAKER BROS. ADVISORS LP 0.12% of their portfolio | 8.1m $20.3m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 7.8m $19.5m | Reduced -946.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 6.8m $16.9m | Added +59.3k |
| Deep Track Capital, LP 0.71% of their portfolio | 6.5m $16.2m | Reduced -2.1m |
| GREAT POINT PARTNERS LLC 3.29% of their portfolio | 6.4m $15.9m | Added +715.0k |
| PALISADE CAPITAL MANAGEMENT, LP 0.25% of their portfolio | 3.8m $9.5m | Added +397.3k |
| TANG CAPITAL MANAGEMENT LLC 1.36% of their portfolio | 3.8m $9.4m | Reduced -3.1m |
| ArrowMark Colorado Holdings LLC 0.11% of their portfolio | 3.6m $8.9m | Reduced -2.0m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 3.5m $8.8m | Added +1.8m |
| STATE STREET CORP 0.00% of their portfolio | 2.6m $6.5m | Reduced -6.3m |
| Velan Capital Investment Management LP 6.64% of their portfolio | 2.5m $6.2m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.0m $4.9m | Added +132.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.5m $3.7m | Added +441.2k |
| Orchard Capital Management, LLC 1.17% of their portfolio | 1.4m $3.5m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.2m $2.9m | Reduced -1.1m |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 1.1m $2.7m | Added +160.7k |
| Clearline Capital LP 0.46% of their portfolio | 1.0m $2.6m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 961.3k $2.4m | Reduced -18.3k |
| Walleye Capital LLC 0.05% of their portfolio | 845.9k $2.1m | Reduced -189.2k |
| MORGAN STANLEY 0.00% of their portfolio | 811.9k $2.0m | Reduced -134.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 798.0k $2.0m | Added +57.0k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 787.1k $2.0m | Reduced -112.5k |
| Pekin Hardy Strauss, Inc. 0.23% of their portfolio | 571.9k $1.4m | Reduced -71.3k |
| Woodline Partners LP 0.02% of their portfolio | 569.2k $1.4m | Reduced -228.7k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 502.8k $1.3m | Added +399.2k |
| NEXPOINT ASSET MANAGEMENT, L.P. 0.10% of their portfolio | 499.1k $1.2m | Unchanged |
| Tejara Capital Ltd 0.72% of their portfolio | 493.6k $1.2m | First filing |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 480.8k $1.2m | Added +455.9k |
| HRT FINANCIAL LP 0.02% of their portfolio | 439.4k $1.1m | Added +58.9k |
| ExodusPoint Capital Management, LP 0.02% of their portfolio | 423.9k $1.1m | Added +10.3k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 403.2k $1.0m | Added +222.3k |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 350.5k $876.2k | Reduced -15.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 349.4k $873.5k | Added +1.8k |
| XTX Topco Ltd 0.18% of their portfolio | 347.0k $867.6k | Added +265.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 335.5k $838.8k | Added +10.3k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 326.7k $816.6k | Reduced -6.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 326.5k $816.0k | New |
| Cheyne Capital Management (UK) LLP 1.40% of their portfolio | 318.0k $795.0k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 301.2k $752.9k | Added +129.7k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 294.1k $735.2k | Added +262.4k |
| KBC Group NV 0.00% of their portfolio | 289.3k $723.0k | Unchanged |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 284.5k $712.0k | Reduced -2.8k |
| NORGES BANK 0.00% of their portfolio | 279.0k $697.5k | Not comparable |
| AXA S.A. 0.00% of their portfolio | 277.7k $694.2k | Reduced -277.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 273.1k $682.7k | Added +120.9k |
| JACOB ASSET MANAGEMENT OF NEW YORK LLC 0.81% of their portfolio | 267.0k $667.6k | Added +27.7k |
| Congress Park Capital LLC 0.41% of their portfolio | 260.1k $650.3k | Added +89.3k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 259.8k $649.5k | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 252.6k $631.0k | Added +3.4k |
| CM Management, LLC 0.75% of their portfolio | 250.0k $625.0k | Reduced -25.0k |
| Swiss National Bank 0.00% of their portfolio | 247.8k $619.5k | Reduced -30.9k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 197.9k $494.8k | Added +157.2k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 176.9k $442.2k | Added +16.1k |
| D.A. DAVIDSON & CO. 0.01% of their portfolio | 173.8k $434.5k | Reduced -23.0k |
| PDT Partners, LLC 0.07% of their portfolio | 167.7k $419.4k | Reduced -136.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 167.7k $419.1k | Reduced -5.4k |
| Weiss Multi-Strategy Advisers LLC 0.01% of their portfolio | 161.3k $403.0k | Reduced -3.7k |
| M&T Bank Corp 0.00% of their portfolio | 148.3k $370.4k | Added +87.8k |
| X-Square Capital, LLC 0.21% of their portfolio | 147.9k $370.0k | Added +95.0k |
| Zweig-DiMenna Associates LLC 0.05% of their portfolio | 140.8k $352.1k | Unchanged |
| FMR LLC 0.00% of their portfolio | 136.1k $340.3k | Reduced -6.1k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 132.9k $332.0k | Added +3.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 130.6k $326.6k | Reduced -12.0k |
| Squarepoint Ops LLC 0.00% of their portfolio | 130.4k $326.0k | Reduced -77.3k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 120.2k $300.5k | Reduced -18.0k |
| Ergoteles LLC 0.01% of their portfolio | 120.0k $299.9k | Reduced -14.0k |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 116.6k $291.0k | Added +30.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 115.6k $289.0k | Reduced -451.3k |
| Laurion Capital Management LP 0.01% of their portfolio | 114.8k $287.0k | Added +496 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 110.8k $276.9k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 87.8k $219.4k | Added +4.1k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 80.8k $202.0k | Added +54.1k |
| Jump Financial, LLC 0.01% of their portfolio | 80.3k $200.7k | Added +13.4k |
| BARCLAYS PLC 0.00% of their portfolio | 74.6k $186.5k | First filing |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 63.4k $158.4k | Reduced -165.2k |
| J.P. Morgan Private Wealth Advisors LLC 0.00% of their portfolio | 60.5k $151.2k | Added +8.4k |
| PIER 88 INVESTMENT PARTNERS LLC 0.04% of their portfolio | 60.0k $150.0k | Added +32.3k |
| J. Goldman & Co LP 0.01% of their portfolio | 54.0k $135.0k | Reduced -320.6k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 53.6k $133.9k | Unchanged |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 51.4k $128.4k | Reduced -1.9k |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 50.8k $126.9k | Reduced -2.9k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 50.7k $126.8k | Added +689 |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 48.7k $121.7k | Reduced -177 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 48.2k $121.0k | Added +2.1k |
| Walleye Trading LLC 0.00% of their portfolio | 44.6k $111.5k | Added +12.1k |
| Legal & General Group Plc 0.00% of their portfolio | 44.3k $110.9k | Reduced -1.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 41.8k $104.4k | Reduced -131 |
| Knights of Columbus Asset Advisors LLC 0.01% of their portfolio | 41.7k $104.4k | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 39.4k $98.6k | Unchanged |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 38.7k $96.8k | Reduced -55.6k |
| UBS Group AG 0.00% of their portfolio | 36.9k $92.2k | Reduced -51.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 35.9k $89.7k | Reduced -11.3k |
| Lido Advisors, LLC 0.00% of their portfolio | 35.3k $88.3k | Unchanged |
| Alpine Global Management, LLC 0.03% of their portfolio | 33.3k $83.0k | New |
| SEARLE & CO. 0.03% of their portfolio | 33.2k $83.1k | Unchanged |
| Quantbot Technologies LP 0.01% of their portfolio | 33.1k $82.8k | Reduced -61.3k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 33.1k $82.7k | Added +6.3k |