HARMONY BIOSCIENCES HLDGS IN HRMY
COM · Common Stock · CUSIP 413197104 · ISIN US4131971040
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersPlymouth Meeting, PA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($854.8k this quarter). Holder counts are more reliable. Shares outstanding: 57.6m as of 2025-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $37.41. Options: 6 managers hold calls ($11.9m notional), 5 hold puts ($7.7m).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 204 |
| Q4 2022 | 242 |
| Q1 2023 | 219 |
| Q2 2023 | 212 |
| Q3 2023 | 207 |
| Q4 2023 | 222 |
| Q1 2024 | 208 |
| Q2 2024 | 220 |
| Q3 2024 | 235 |
| Q4 2024 | 248 |
| Q1 2025 | 273 |
| Q2 2025 | 280 |
| Q3 2025 | 297 |
| Q4 2025 | 325 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 88 | 120 |
| Q2 2024 | 109 | 94 |
| Q3 2024 | 107 | 109 |
| Q4 2024 | 157 | 74 |
| Q1 2025 | 137 | 102 |
| Q2 2025 | 162 | 102 |
| Q3 2025 | 160 | 112 |
| Q4 2025 | 168 | 141 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $4.9m | $1.6m | 0.32 |
| Q2 2025 | $10.5m | $2.3m | 0.21 |
| Q3 2025 | $30.8m | $8.9m | 0.29 |
| Q4 2025 | $11.9m | $7.7m | 0.65 |
Biggest buyers
| SG Americas Securities, LLC | Added | +938.8k |
| ARMISTICE CAPITAL, LLC | New | +500.0k |
| AQR CAPITAL MANAGEMENT LLC | Added | +458.3k |
| CITADEL ADVISORS LLC | Added | +352.4k |
| JANUS HENDERSON GROUP PLC | Added | +305.9k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | New | +203.5k |
| ROYCE & ASSOCIATES LP | Added | +196.4k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | Added | +196.2k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | Added | +193.4k |
| AMERICAN CENTURY COMPANIES INC | Added | +172.1k |
Biggest sellers
| Valor Management LLC | Reduced | -1.2m |
| FMR LLC | Reduced | -734.2k |
| VANGUARD GROUP INC | Reduced | -283.8k |
| MARSHALL WACE, LLP | Reduced | -255.9k |
| UBS Group AG | Reduced | -205.9k |
| Jefferies Financial Group Inc. | Reduced | -173.7k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -157.5k |
| JPMORGAN CHASE & CO | Reduced | -148.7k |
| Atle Fund Management AB | Sold out | -92.1k |
| DEUTSCHE BANK AG\ | Reduced | -81.5k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $5.8m154.8k shares |
| CITADEL ADVISORS LLC | Reduced | $2.3m60.5k shares |
| JANE STREET GROUP, LLC | Added | $2.0m53.9k shares |
| GROUP ONE TRADING LLC | Reduced | $636.1k17.0k shares |
| IMC-Chicago, LLC | Added | $595.0k15.9k shares |
| MILLENNIUM MANAGEMENT LLC | New | $561.3k15.0k shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $3.8m101.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.4m63.4k shares |
| CITADEL ADVISORS LLC | Added | $1.0m27.4k shares |
| IMC-Chicago, LLC | New | $467.8k12.5k shares |
| GROUP ONE TRADING LLC | Unchanged | $3.7k100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.3 pts · filed 2026-10-27 | 12.6% |
| Marshman Fund Trust II 13G · exempt (held before listing) filed 2025-02-10 | 10.6% |
| FMR LLC 13G · institution -1.3 pts · filed 2026-02-05 | 5.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.1% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), Valor IV Pharma Holdings, LLC (3.2%, 2025-11-14)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 1 | $389.5k | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 1 | $1.4m | — |
| Q4 2024 | 0 | — | 2 | $141.5m | $869.9k |
| Q1 2025 | 0 | — | 3 | $4.4m | $4.4m |
| Q2 2025 | 0 | — | 1 | $227.4k | $227.4k |
| Q3 2025 | 0 | — | 1 | $787.4k | $787.4k |
| Q4 2025 | 0 | — | 2 | $2.0m | $2.0m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-12 | Dayno Jeffrey M. PRESIDENT, CEO, director | Sold plan | $1.0m25.9k shares |
| 2025-12-05 | Kapadia Sandip CHIEF FINANCIAL OFFICER | Sold plan | $790.8k20.0k shares |
| 2025-11-21 | Kapadia Sandip CHIEF FINANCIAL OFFICER | Sold plan | $119.9k3.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 7.1m $265.3m | Added +162.7k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.8m $180.1m | Reduced -283.8k |
| FMR LLC 0.01% of their portfolio | 3.1m $116.5m | Reduced -734.2k |
| AMERICAN CENTURY COMPANIES INC 0.03% of their portfolio | 1.8m $68.9m | Added +172.1k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.8m $68.5m | Added +139.1k |
| STATE STREET CORP 0.00% of their portfolio | 1.7m $62.2m | Added +8.2k |
| LSV ASSET MANAGEMENT 0.14% of their portfolio | 1.7m $62.0m | Added +62.2k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.03% of their portfolio | 1.5m $55.8m | Added +196.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $47.6m | Added +12.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.06% of their portfolio | 1.1m $40.1m | Reduced -66.6k |
| SG Americas Securities, LLC 0.05% of their portfolio | 961.7k $36.0m | Added +938.8k |
| MORGAN STANLEY 0.00% of their portfolio | 817.5k $30.6m | Reduced -30.4k |
| AQR CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 813.9k $30.5m | Added +458.3k |
| Boston Partners 0.03% of their portfolio | 708.9k $26.4m | Reduced -45.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 569.4k $21.3m | Reduced -77.3k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 541.3k $20.3m | Reduced -29.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 525.1k $19.7m | Added +130.0k |
| NOMURA HOLDINGS INC 0.05% of their portfolio | 510.0k $19.1m | Added +72.9k |
| ARMISTICE CAPITAL, LLC 0.46% of their portfolio | 500.0k $18.7m | New |
| venBio Partners LLC 8.46% of their portfolio | 489.2k $18.3m | Unchanged |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.02% of their portfolio | 459.1k $17.2m | Added +193.4k |
| Invesco Ltd. 0.00% of their portfolio | 450.8k $16.9m | Added +47.5k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 420.4k $15.7m | Added +352.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 418.9k $15.7m | Reduced -13.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 418.0k $15.6m | Reduced -38.4k |
| 683 Capital Management, LLC 1.29% of their portfolio | 415.0k $15.5m | Added +133.0k |
| ALGERT GLOBAL LLC 0.21% of their portfolio | 359.8k $13.5m | Added +91.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 344.2k $12.9m | Reduced -81.5k |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 322.3k $12.1m | Added +305.9k |
| Man Group plc 0.02% of their portfolio | 306.7k $11.5m | Added +29.7k |
| Trexquant Investment LP 0.10% of their portfolio | 299.4k $11.2m | Added +27.4k |
| UBS Group AG 0.00% of their portfolio | 297.2k $11.1m | Reduced -205.9k |
| Tieton Capital Management, LLC 3.80% of their portfolio | 297.1k $11.1m | Reduced -1.5k |
| Pacer Advisors, Inc. 0.03% of their portfolio | 290.4k $10.9m | Reduced -72.6k |
| TANG CAPITAL MANAGEMENT LLC 0.54% of their portfolio | 290.3k $10.9m | Added +9.1k |
| CAPITAL MANAGEMENT CORP /VA 1.73% of their portfolio | 281.7k $10.5m | Reduced -41.2k |
| ROYCE & ASSOCIATES LP 0.11% of their portfolio | 278.2k $10.4m | Added +196.4k |
| CX Institutional 0.31% of their portfolio | 275.8k $10.3m | Added +45.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 275.1k $10.3m | Added +84.6k |
| VICTORY CAPITAL MANAGEMENT INC 0.01% of their portfolio | 272.6k $10.2m | Added +36.9k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 264.4k $9.9m | Reduced -269 |
| FEDERATED HERMES, INC. 0.02% of their portfolio | 263.8k $9.9m | Reduced -34.4k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 252.6k $9.5m | Added +21.6k |
| Connor, Clark & Lunn Investment Management Ltd. 0.02% of their portfolio | 249.1k $9.3m | Added +17.2k |
| Public Sector Pension Investment Board 0.03% of their portfolio | 248.1k $9.3m | Added +62.3k |
| Bridge City Capital, LLC 2.61% of their portfolio | 237.1k $8.9m | Reduced -22.8k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio | 234.9k $8.8m | Added +116 |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 231.7k $8.7m | Added +27.2k |
| Bridgewater Associates, LP 0.03% of their portfolio | 228.5k $8.6m | Added +17.0k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 221.6k $8.3m | Added +108.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 221.5k $8.3m | Added +127.3k |
| Pictet Asset Management Holding SA 0.01% of their portfolio | 207.4k $7.9m | Reduced -9.9k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 207.0k $7.7m | Reduced -18.3k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 203.5k $7.6m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 199.4k $7.5m | Reduced -148.7k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 169.7k $6.3m | Added +630 |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 155.4k $5.8m | Added +42.1k |
| HRT FINANCIAL LP 0.02% of their portfolio | 155.1k $5.8m | New |
| CITIGROUP INC 0.00% of their portfolio | 154.5k $5.8m | Reduced -23.5k |
| Walleye Capital LLC 0.03% of their portfolio | 141.8k $5.3m | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 139.9k $5.2m | Added +70.1k |
| Hudson Bay Capital Management LP 0.03% of their portfolio | 138.5k $5.2m | New |
| Hillsdale Investment Management Inc. 0.14% of their portfolio | 137.4k $5.1m | Unchanged |
| Timothy G. Youngquist 2020 Irrevocable Trust 4.04% of their portfolio | 125.9k $4.7m | First filing |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 117.2k $4.4m | Added +80.5k |
| Valor Management LLC 7.95% of their portfolio | 117.1k $4.4m | Reduced -1.2m |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 116.9k $4.4m | Reduced -6.1k |
| BARCLAYS PLC 0.00% of their portfolio | 115.5k $4.3m | Added +4.0k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 114.3k $4.3m | Reduced -78.3k |
| Legal & General Group Plc 0.00% of their portfolio | 107.2k $4.0m | Reduced -5.8k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 104.4k $3.9m | Added +64.6k |
| DENALI ADVISORS LLC 0.41% of their portfolio | 97.8k $3.7m | Reduced -4.2k |
| Hennion & Walsh Asset Management, Inc. 0.12% of their portfolio | 96.7k $3.6m | Added +10.3k |
| Edgestream Partners, L.P. 0.10% of their portfolio | 90.8k $3.4m | Added +77.4k |
| WEDGE CAPITAL MANAGEMENT L L P/NC 0.06% of their portfolio | 88.9k $3.3m | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 88.3k $3.3m | Reduced -8.3k |
| Brandywine Global Investment Management, LLC 0.02% of their portfolio | 85.7k $3.2m | Reduced -60.5k |
| Swiss National Bank 0.00% of their portfolio | 85.1k $3.2m | Added +1.6k |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 84.1k $3.1m | Added +57.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 84.0k $3.1m | New |
| Nuveen, LLC 0.00% of their portfolio | 83.1k $3.1m | Reduced -3.1k |
| Tetragon Partners GP Ltd 0.65% of their portfolio | 82.8k $3.1m | New |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 82.3k $3.1m | Reduced -157.5k |
| CAPITAL FUND MANAGEMENT S.A. 0.03% of their portfolio | 78.0k $2.9m | Added +28.1k |
| Zuckerman Investment Group, LLC 0.25% of their portfolio | 75.5k $2.8m | Reduced -47.8k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 73.6k $2.8m | Added +60.5k |
| Hedeker Wealth, LLC 0.58% of their portfolio | 73.6k $2.8m | Reduced -6.7k |
| Pavaki Capital Management LLC 1.91% of their portfolio | 73.0k $2.7m | First filing |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 72.7k $2.7m | Added +16.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 72.7k $2.7m | Reduced -1.9k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 70.1k $2.6m | Added +12.0k |
| CONNORS INVESTOR SERVICES INC 0.22% of their portfolio | 69.7k $2.6m | Reduced -2.0k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 69.5k $2.6m | Added +69.1k |
| Engineers Gate Manager LP 0.03% of their portfolio | 68.3k $2.6m | Reduced -21.8k |
| Cresset Asset Management, LLC 0.01% of their portfolio | 67.4k $2.5m | Added +221 |
| CLARK ESTATES INC/NY 0.61% of their portfolio | 67.3k $2.5m | Unchanged |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 66.6k $1.9m | Reduced -808 |
| Aurora Investment Counsel 1.30% of their portfolio | 66.1k $2.5m | Added +2.5k |
| HUSSMAN STRATEGIC ADVISORS, INC. 0.57% of their portfolio | 63.0k $2.4m | Added +21.0k |
| Quantedge Capital Pte Ltd 1.09% of their portfolio | 61.3k $2.3m | Reduced -3.4k |